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| 1 | Defect engineering of molybdenum disulfide through ion irradiation to boost hydrogen evolution reaction performance显示文摘The inert basal plane of molybdenum disulfide (MoS2) restrains its further hydrogen evolution reaction (HER) performance.This work attempts ion irradiation to activate inert basal plane of MoS2 nanosheet to improve its electrocatalytic performance.Experimental results demonstrate the sulphur vacancies generated by ion irradiation on the basal plane of MoS2 mainly boost the efficiency of HER performance.The moderate fluence of carbon ion irradiation gains the optimum HER performance with an onset potential of 77 mV and Tafel slope of 66 mV/dec. | Cheng Sun Peipei Wang Hao Wang Chuan Xu Juntong Zhu Yanxia Liang Ying Su Yining Jiang Wenqi Wu Engang Fu Guifu Zou | 2019 | Nano Research2019，12，7： | 3 |
| 2 | Color-preserving passive radiative cooling for an actively temperature-regulated enclosure显示文摘Active temperature control devices are widely used for the thermal management of enclosures,including vehicles and buildings.Passive radiative cooling has been extensively studied;however,its integration with existing actively temperature regulated and decorative enclosures has slipped out of the research at status quo.Here,we present a photonic-engineered dual-side thermal management strategy for reducing the active power consumption of the existing temperature-regulated enclosure without sacrificing its aesthetics.By coating the exterior and interior of the enclosure roof with two visible-transparent films with distinctive wavelength-selectivity,simultaneous control over the energy exchange among the enclosure with the hot sun,the cold outer space,the atmosphere,and the active cooler can be implemented.A power-saving of up to 63%for active coolers of the enclosure is experimentally demonstrated by measuring the heat flux compared to the ordinary enclosure when the set temperature is around 26℃.This photonic-engineered dual-side thermal management strategy offers facile integration with the existing enclosures and represents a new paradigm toward carbon neutrality. | Yining Zhu Hao Luo Chenying Yang Bing Qin Pintu Ghosh Sandeep Kaur Weidong Shen Min Qiu Pavel Belov Qiang Lie | 2022 | Light(Science & Applications)2022，11，6： | 2 |
| 3 | Optical Properties and Source Analysis of Aerosols over a Desert Area in Dunhuang,Northwest China显示文摘Aerosol observational data for 2012 obtained from Dunhuang Station of CARE-China(Campaign on Atmospheric Aerosol Research Network of China) were analyzed to achieve in-depth knowledge of aerosol optical properties over Dunhuang region. The results showed that the annual average aerosol optical depth(AOD) at 500 nm was 0.32 ± 0.06, and the ?ngstr?m exponent(α) was 0.73 ± 0.27. Aerosol optical properties revealed significant seasonal characteristics. Frequent sandstorms in MAM(March–April–May) resulted in the seasonal maximum AOD, 0.41 ± 0.04, and a relatively smaller αvalue, 0.44 ± 0.04. The tourism seasons, JJA(June–July–August) and SON(September–October–November) coincide with serious emissions of small anthropogenic aerosols. While in DJF(December–January–February), the composition of the atmosphere was a mixture of dust particles and polluted aerosols released by domestic heating; the average AOD and αwere 0.29 ± 0.02 and 0.66 ± 0.17, respectively. Different air masses exhibited different degrees of influence on the aerosol concentration over Dunhuang in different seasons. During MAM, ranges of AOD(0.11–1.18) and α(0.06–0.82) were the largest under the dust influence of northwest-short-distance air mass in the four trajectories. Urban aerosols transported by northwest-short-distance air mass accounted for a very large proportion in JJA and the mixed aerosols observed in SON were mainly conveyed by air masses from the west. In DJF, the similar ranges of AOD and α under the three air mass demonstrated the analogous diffusion effects on regional pollutants over Dunhuang. | Yongjing MA Jinyuan XIN Yining MA Lingbin KONG Kequan ZHANG Wenyu ZHANG Yuesi WANG Xiuqin WANG Yongfeng ZHU | 2017 | Advances in Atmospheric Sciences2017，34，8： | 2 |
| 4 | Whole-infrared-band camouflage with dual-band radiative heat dissipation显示文摘Advanced multispectral detection technologies have emerged as a significant threat to objects,necessitating the use of multiband camouflage.However,achieving effective camouflage and thermal management across the entire infrared spectrum,especially the short-wave infrared(SWIR)band,remains challenging.This paper proposes a multilayer wavelength-selective emitter that achieves effective camouflage across the entire infrared spectrum,including the near-infrared(NIR),SWIR,mid-wave infrared(MWIR),and long-wave infrared(LWIR)bands,as well as the visible(VIS)band.Furthermore,the emitter enables radiative heat dissipation in two non-atmospheric windows(2.5-3μm and 5-8μm).The emitter’s properties are characterized by low emittance of 0.270/0.042/0.218 in the SWIR/MWIR/LWIR bands,and low reflectance of 0.129/0.281 in the VIS/NIR bands.Moreover,the high emittance of 0.742/0.473 in the two non-atmospheric windows ensures efficient radiative heat dissipation,which results in a temperature decrement of 14.4℃ compared to the Cr reference at 2000Wm^(−2) input power density.This work highlights the role of solar radiance in camouflage,and provides a comprehensive guideline for developing multiband camouflage compatible with radiative heat dissipation,from the visible to LWIR. | Bing Qin Yining Zhu Yiwei Zhou Min Qiu Qiang Li | 2023 | Light(Science & Applications)2023，12，11： | 1 |
| 5 | Noise re- duction with low-dose CT data based on a modified ROF model 显示文摘 | Zhu Yining Zhao Mengliu Zhao Yunsong | 2012 | Optics Express2012，20，17： | 1 |
| 6 | A corona modulation device structure and mechanism based on perovskite quantum dots random laser pumped using an electron beam显示文摘Although laser pumping using electron beam(EB)has high transient power output and easy modulation based on perovskite quantum dot(PQD)film,its lasing emitting direction is the same as the pumped EB's direction.Thus,realizing the conventional direct device structure through the film lasing mechanism is extremely difficult.Therefore,using the random lasing principle,herein,we proposed a corona modulation device structure based on PQDs random laser pumped using an EB.We discussed and stimulated the optimized designed method of the device in terms of parameters of the electronic optical device and the utilization ratio of output power and its modulation extinction ratio,respectively.According to the simulation results,this type of device structure can effectively satisfy the new random lasing mechanism in terms of high-speed and high-power modulation. | Yan ZHU Yining MU Fanqi TANG Peng DU Hang REN | 2020 | Frontiers of Optoelectronics2020，13，3： | 1 |
| 7 | Characterization of homoisoflavonoidsin different cultivation regions of Ophiopogon japonicusand related antioxidant activity显示文摘 | Yining Lin Danni Zhu Jin Qi | 2010 | J Pharm BiomedAnal2010，52，： | 1 |
| 8 | An approach to increasing the resolution of industrial CT images based on an aperture collimator显示文摘 | Yining Zhu Defeng Chen Yunsong 2hao Hongwei Li Peng Zhang | 2013 | Optics Express2013，21，27： | 1 |
| 9 | Night-time radiative warming using the atmosphere显示文摘Night-time warming is vital for human production and daily life.Conventional methods like active heaters are energy-intensive,while passive insulating films possess restrictions regarding space consumption and the lack of heat gain.In this work,a nanophotonic-based night-time warming strategy that passively inhibits thermal radiation of objects while actively harnessing that of atmosphere is proposed.By using a photonic-engineered thin film that exhibits high reflectivity(~0.91)in the atmospheric transparent band(8-14μm)and high absorptivity(~0.7)in the atmospheric radiative band(5-8 and 14-16μm),temperature rise of 2.1℃/4.4℃compared to typical low-e film and broadband absorber is achieved.Moreover,net heat loss as low as 9Wm-2 is experimentally observed,compared to 16 and 39Wm-2 for low-e film and broadband absorber,respectively.This strategy suggests an innovative way for sustainable warming,thus contributes to addressing the challenges of climate change and promoting global carbon neutrality. | Yining Zhu Yiwei Zhou Bing Qin Rui Qin Min Qiu Qiang Li | 2023 | Light(Science & Applications)2023，12，12： | 0 |
| 10 | Investigation on the Mechanical Properties and Shape Memory Effect of Landing Buffer Structure Based on NiTi Alloy Printing显示文摘With the deepening of human research on deep space exploration,our research on the soft landing methods of landers has gradually deepened.Adding a buffer and energy-absorbing structure to the leg structure of the lander has become an effective design solution.Based on the energy-absorbing structure of the leg of the interstellar lander,this paper studies the appearance characteristics of the predatory feet of the Odontodactylus scyllarus.The predatory feet of the Odontodactylus scyllarus can not only hit the prey highly when preying,but also can easily withstand the huge counter-impact force.The predatory feet structure of the Odontodactylus scyllarus,like a symmetrical cone,shows excellent rigidity and energy absorption capacity.Inspired by this discovery,we used SLM technology to design and manufacture two nickel-titanium samples,which respectively show high elasticity,shape memory,and get better energy absorption capacity.This research provides an effective way to design and manufacture high-mechanical energy-absorbing buffer structures using bionic 3D printing technology and nickel-titanium alloys. | Zhenglei Yu Renlong Xin Zezhou Xu Yining Zhu Xiaolong Zhang Shijie Hao Zhihui Zhang Ping Liang | 2023 | Chinese Journal of Mechanical Engineering2023，36，4： | 0 |
| 11 | Nanoparticles with rough surface improve the therapeutic effect of photothermal immunotherapy against melanoma显示文摘Photothermal therapy has been intensively investigated for treating cancer in recent years.However,the long-term therapeutic outcome remains unsatisfying due to the frequently occurred metastasis and recurrence.To address this challenge,immunotherapy has been combined with photothermal therapy to activate anti-tumor immunity and relieve the immunosuppressive microenvironment within tumor sites.Here,we engineered silica-based core-shell nanoparticles(JQ-1@PSNs-R),in which silica cores were coated with the photothermal agent polydopamine,and a bromodomain-containing protein 4(BRD4) inhibitor JQ-1 was loaded in the polydopamine layer to combine photo thermal and immune therapy for tumor elimination.Importantly,to improve the therapeutic effect,we increased the surface roughness of the nanoparticles by hydrofluoric acid(HF) etching during the fabrication process,and found that the internalization of JQ-1@PSNs-R was significantly improved,leading to a strengthened photothermal killing effect as well as the increased intracellular delivery of JQ-1.In the animal studies,the multifunctional nanoparticles with rough surfaces effectively eradicated melanoma via photothermal therapy,successfully activated tumor-specific immune responses against residual tumor cells,and further prevented tumor metastasis and recurrence.Our results indicated that JQ-1@PSNs-R could serve as an innovative and effective strategy for combined cancer therapy. | Jiao Xue Yining Zhu Shuting Bai Chunting He Guangsheng Du Yuandong Zhang Yao Zhong Wenfei Chen Hairui Wang Xun Sun | 2022 | Acta Pharmaceutica Sinica B2022，12，6： | 0 |
| 12 | Molecular Detection of FGFR2 Rearrangements in Resected Intrahepatic Cholangiocarcinomas:FISH Could Be An Ideal Method in Patients with Histological Small Duct Subtype显示文摘Background and Aims:Intrahepatic cholangiocarcinoma(ICC)is a subtype of primary liver cancer for which effective therapeutic agents are lacking.Fibroblast growth factor receptor 2(FGFR2)has become a promising therapeutic target in ICC;however,its incidence and optimum testing method have not been fully assessed.This study investigated the rearrangement of FGFR2 in intrahepatic cholangiocarcinoma using multiple molecular detection methods.Methods:The samples and clinical data of 167 patients who underwent surgical resection of intrahepatic cholangiocarcinoma in Zhongshan hospital,Fudan university were collected.The presence of FGFR2 gene rearrangement was confirmed using fluorescence in situ hybridization(FISH)and targeted next-generation sequencing(NGS).FGFR2 protein expression was determined using immunohistochemistry(IHC).The concordance between the methods was statistically compared.PD-L1 expression was also assessed in this cohort.The clinicopathological characteristics and genomic profile related to FGFR2 rearrangements were also analyzed to assist candidatescreening for targeted therapies.Results:FGFR2 rearrangement was detected in 21 of the 167 ICC cases(12.5%)using FISH.NGS analysis revealed that FGFR2 rearrangement was present in 16 of the 20 FISH-positive cases,which was consistent with the FISH results(kappa value=0.696,p<0.01).IHC showed that 80 of the 167 cases(48%)were positive for FGFR2 expression,which was discordant with both FISH and NGS results.By comparison,FGFR2-positivity tended to correlate with unique clinicopathological subgroups,featuring early clinical stage,histologically small duct subtype,and reduced mucus production(P<0.05),with improved overall survival(p<0.05).FGFR2-positivity was not associated with PD-L1 expression in ICCs.In genome research,we identified eight partner genes fused with FGFR2,among which FGFR2-BICC1 was the most common fusion type.BAP1,CDKN2A,and CDKN2B were the most common concomitant genetic alterations of FGFR2,whereas KRAS and IDH1 mutations were mutually exclusive to FGFR2 rearrangements.Conclusions:FISH achieved satisfactory concordance with NGS,has potential value for FGFR2 screening for targeted therapies.FGFR2 detection should be prioritized for unique clinical subgroups in ICC,which features a histological small duct subtype,early clinical stage,and reduced mucus production. | Yining Zou Kun Zhu Yanrui Pang Jing Han Xin Zhang Zhengzeng Jiang Yufeng Huang Wenyi Gu Yuan Ji | 2023 | Journal of Clinical and Translational Hepatology2023，11，6： | 0 |
| 13 | Rh(Ⅲ)-Catalyzed annulative aldehydic C-H functionalization for accessing ring-fluorinated benzo[b]azepin-5-ones显示文摘A new Rh(Ⅲ)-catalyzed aldehydic C-H activation/[4+3]annulation cascade of N-sulfonyl-2-aminobenzaldehydes with gem-difluorocyclopropenes is reported for the first time,and used to produce a range of hitherto unreported precedentedβ-monofluorinated benzo[b]azepin-5-ones with good yields and complete regioselectivity.This approach features a broad substrate scope,good functional group tolerance,and high regioselectivity,which may include Rh(Ⅲ)-catalyzed aldehydic C-H activation,tandem site-/regioselective insertion,defluorinated ring-scission,and 1,2-elimination. | Qiuyun Li Kelu Yan Yannan Zhu Gang Qi Yining Wang Wen-Juan Hao Bo Jiang | 2023 | Chinese Chemical Letters2023，34，6： | 0 |
| 14 | Association between exposure to particulate matter during pregnancy and birthweight:a systematic review and a metaanalysis of birth cohort studies显示文摘Studies of the associations between maternal exposure to particulate matter(PM) and risk of adverse effects on fetal growth are inconsistent and inconclusive. This question can be well answered by carefully designed birth cohort studies; however, so far the evidence from such studies has not come to the same conclusion. We sought to evaluate the association between maternal exposures to PM and low birthweight(LBW) enrolling 14 studies from 11 centers,and to explore the influence of trimester and exposure assessment methods on between-center heterogeneity in this association. Data were derived from PubMed, Embase, Google Scholar, CNKI, and WanFang database, references from relevant articles, and results from published studies until March 2017. Using a random-effects meta-analysis, we combined the coefficient and odds ratios(OR) of individual studies conducted among 14 birth cohort studies.Random-effect meta-analysis results suggested that a 17% and 6% increase in risk of LBW was relevant to a 10 μg/m^3 rise in PM_(2.5) and PM_(10) exposure concentrations at the 3 rd trimester(pooled odds ratios(OR), 1.17 and 1.06; 95%confidence interval(CI), 0.94-1.46 and 0.97-1.15, respectively), but the null value was included in our 95% CI. Our results showed that exposure to PM_(2.5) and PM_(10) during pregnancy has a positive relevance to LBW based on birth cohort studies. However, neither reached formal statistical significance. Negative impacts on outcomes of birth is implied by maternal exposure to PM. Further mechanistic researches are needed to explain the connection between PM pollution and LBW. | Yinwen Ji Fei Song Bo Xu Yining Zhu Chuncheng Lu Yankai Xia | 2019 | The Journal of Biomedical Research2019，33，1： | 0 |
| 15 | Laser capture microdissection for biomedical research: towards high-throughput, multi-omics, and single-cell resolution显示文摘Spatial omics technologies have become powerful methods to provide valuable insights into cells and tissues within a complex context,significantly enhancing our understanding of the intricate and multifaceted biological system.With an increasing focus on spatial heterogeneity,there is a growing need for unbiased,spatially resolved omics technologies.Laser capture microdissection(LCM)is a cutting-edge method for acquiring spatial information that can quickly collect regions of interest(ROIs)from heterogeneous tissues,with resolutions ranging from single cells to cell populations.Thus,LCM has been widely used for studying the cellular and molecular mechanisms of diseases.This review focuses on the differences among four types of commonly used LCM technologies and their applications in omics and disease research.Key attributes of application cases are also highlighted,such as throughput and spatial resolution.In addition,we comprehensively discuss the existing challenges and the great potential of LCM in biomedical research,disease diagnosis,and targeted therapy from the perspective of high-throughput,multi-omics,and single-cell resolution. | Wenbo Guo Yining Hu Jingyang Qian Lidan Zhu Junyun Cheng Jie Liao Xiaohui Fan | 2023 | Journal of Genetics and Genomics2023，50，9： | 0 |
| 16 | Transcriptome characterization and SSR discovery in Squaliobarbus curriculus显示文摘Squaliobarbus curriculus is a eurythermic ?sh found mainly in East Asia. The natural germplasm resources of this species, an organism of potential economic aquacultural importance, have recently been threatened by over?shing and habitat degradation. The objective of this study was to obtain functional genomic resources and candidate microsatellite markers for future genetic observation and germplasm protection of S. curriculus. Illumina paired-end sequencing generated over 22.20 million clean reads, which were assembled into 204 027 transcripts with an average length of 1 457 bp. A total of 112 570 protein-coding sequences(55.17%) were predicted, 111 934 of which had signi?cant matches in the NCBI nonredundant protein database. Overall, 60 450, 34 830, and 77 755 transcripts were assigned to Gene Ontology, Clusters of Orthologous Groups, and Eukaryotic Orthologous Groups categories, respectively.In addition, 44 781 transcripts(21.95%) were mapped to 230 KEGG pathways. A total of 51 426 candidate simple sequence repeat(SSR) markers were identi?ed and used to design 36 149 PCR primer pairs. Fifty of these primer pairs were randomly selected for PCR validation in 32 S. curriculus specimens, which resulted in 25 pairs yielding the expected products. Further analysis revealed that 40%(10) of the 25 ampli?ed loci were polymorphic. The transcriptomic pro?le and SSR repertoire obtained in this study should facilitate population genetic studies and germplasm resource protection of S. curriculus. | LI Caijuan TENG Teng SHEN Fanfan GUO Jinqiang CHEN Yining ZHU Chuankun LING Qufei | 2019 | Journal of Oceanology and Limnology2019，37，1： | 0 |
| 17 | Shock-Resistant and Energy-Absorbing Properties of Bionic NiTi Lattice Structure Manufactured by SLM显示文摘Each specific structure of organisms is the best choice under specific circumstances.The excellent characteristic structures of these organisms have great application potential in the design and multi-functional optimization of energy-absorbing structures such as vehicle collisions,satellite landings,and military equipment.In this paper,using the principle of structural bionics,using the advantages of the honeycomb structure and the light weight and high strength of beetle elytra,four bionic lattice structures are studied:CH,ZPRH,SCH and IBE.Using NiTi shape memory alloy,a unique material as the base material,samples are prepared using selective laser melting(SLM)technology.By comparing the test results of the quasi-static compression test with the results of the numerical simulation,it is found that compared with the other three bionic lattice structures,the SCH structure has the best energy absorption effect in the effective stroke in the test,and the specific energy absorption can reach 6.32 J/g.ZPRH,SCH,and IBE structures not only have good and stable deformation behavior,but also have excellent impact resistance and shape memory properties.The design of these structures provides a reference for the design of anti-shock cushioning structures with self-recovery functions in the future. | Zhenglei Yu Renlong Xin Zezhou Xu Luming Sha Lixin Chen Yining Zhu Ping Liang Zhihui Zhang Zhenze Liu Qing Cao | 2022 | Journal of Bionic Engineering2022，19，6： | 0 |
| 18 | Genetic and histological relationship between pheromone-secreting tissues of the musk gland and skin of juvenile Chinese forest musk deer(Moschus berezovskii Flerov,1929)显示文摘Background The musk glands of adult male Chinese forest musk deer(Moschus berezovskii Flerov,1929)(FMD),which are considered as special skin glands,secrete a mixture of sebum,lipids,and proteins into the musk pod.Together,these components form musk,which plays an important role in attracting females during the breeding season.However,the relationship between the musk glands and skin of Chinese FMD remains undiscovered.Here,the musk gland and skin of Chinese FMD were examined using histological analysis and RNA sequencing(RNA-seq),and the expression of key regulatory genes was evaluated to determine whether the musk gland is derived from the skin.Methods A comparative analysis of musk gland anatomy between juvenile and adult Chinese FMD was conducted.Then,based on the anatomical structure of the musk gland,skin tissues from the abdomen and back as well as musk gland tissues were obtained from three juvenile FMD.These tissues were used for RNA-seq,hematoxylin-eosin(HE)staining,immunohistochemistry(IHC),western blot(WB),and quantitative real-time polymerase chain reaction(qRT-PCR)experiments.Results Anatomical analysis showed that only adult male FMD had a complete glandular organ and musk pod,while juvenile FMD did not have any well-developed musk pods.Transcriptomic data revealed that 88.24%of genes were co-expressed in the skin and musk gland tissues.Kyoto Encyclopedia of Genes and Genomes(KEGG)signaling pathway analysis found that the genes co-expressed in the abdomen skin,back skin,and musk gland were enriched in biological development,endocrine system,lipid metabolism,and other pathways.Gene Ontology(GO)enrichment analysis indicated that the genes expressed in these tissues were enriched in biological processes such as multicellular development and cell division.Moreover,the Metascape predictive analysis tool demonstrated that genes expressed in musk glands were skin tissue-specific.qRT-PCR and WB revealed that sex-determining region Y-box protein 9(Sox9),Caveolin-1(Cav-1),and androgen receptor(AR)were expressed in all three tissues,although the expression levels differed among the tissues.According to the IHC results,Sox9 and AR were expressed in the nuclei of sebaceous gland,hair follicle,and musk gland cells,whereas Cav-1 was expressed in the cell membrane.Conclusions The musk gland of Chinese FMD may be a derivative of skin tissue,and Sox9,Cav-1,and AR may play significant roles in musk gland development. | Long LI Heran CAO Jinmeng YANG Tianqi JIN Yuxuan MA Yang WANG Zhenpeng LI Yining CHEN Huihui GAO Chao ZHU Tianhao YANG Yalong DENG Fangxia YANG Wuzi DONG | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，9： | 0 |
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