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| 1 | Plant abiotic stress response and nutrient use efficiency显示文摘Abiotic stresses and soil nutrient limitations are major environmental conditions that reduce plant growth,productivity and quality.Plants have evolved mechanisms to perceive these environmental challenges,transmit the stress signals within cells as well as between cells and tissues,and make appropriate adjustments in their growth and development in order to survive and reproduce.In recent years,significant progress has been made on many fronts of the stress signaling research,particularly in understanding the downstream signaling events that culminate at the activation of stress-and nutrient limitation-responsive genes,cellular ion homeostasis,and growth adjustment.However,the revelation of the early events of stress signaling,particularly the identification of primary stress sensors,still lags behind.In this review,we summarize recent work on the genetic and molecular mechanisms of plant abiotic stress and nutrient limitation sensing and signaling and discuss new directions for future studies. | Zhizhong Gong Liming Xiong Huazhong Shi Shuhua Yang Luis R.Herrera-Estrella Guohua Xu Dai-Yin Chao Jingrui Li Peng-Yun Wang Feng Qin Jigang Li Yanglin Ding Yiting Shi Yu Wang Yongqing Yang Yan Guo Jian-Kang Zhu | 2020 | Science China(Life Sciences)2020，63，5： | 94 |
| 2 | Asimple andsensitive GCmethod for determination of N-methylpyrrolidine in cefepime and its preparation 显示文摘 | Chen Guiliang Liu Guyu Qin Feng Wang Yiting | 2003 | Journal of Pharmaceutical and Biomedical Analysis2003，33，： | 1 |
| 3 | 4350<ce:hsp sp='0.25'/>W quasi-continuous-wave operation of a diode face-pumped ceramic Nd: YAG slab laser显示文摘 | Junchi Chen Jiang Li Jialin Xu Wenbin Liu Yong Bo Xiqi Feng Yiting Xu Dongliang Jiang Zhongzheng Chen Yubai Pan Yading Guo Biao Yan Chang Guo Lei Yuan Hongtao Yuan Yanyong Lin Yunsheng Xiao Qinjun Peng Wenqiang Lei Dafu Cui Zuyan Xu | 2014 | Optics and Laser Technology2014，，： | 1 |
| 4 | Aquaporin 9 is involved in CRC metastasis through DVL2-dependent Wnt/β-catenin signaling activation显示文摘Background:Aquaporin 9(AQP9)is permeable to water or other small molecules,and plays an important role in various cancers.We previously found that AQP9 was related to the efficacy of chemotherapy in patients with colorectal cancer(CRC).This study aimed to identify the role and regulatory mechanism of AQP9 in CRC metastasis.Methods:The clinical significance of AQP9 was analysed by using bioinformatics and tissue microarray.Transcriptome sequencing,Dual-Luciferase Reporter Assay,Biacore,and co-immunoprecipitation were employed to demonstrate the regulatory mechanism of AQP9 in CRC.The relationship between AQP9 and CRC metastasis was verified in vitro and in vivo by using real-time cell analysis assay,high content screening,and liver metastasis models of nude mice.Results:We found that AQP9 was highly expressed in metastatic CRC.AQP9 overexpression reduced cell roundness and enhanced cell motility in CRC.We further showed that AQP9 interacted with Dishevelled 2(DVL2)via the C-terminal SVIM motif,resulting in DVL2 stabilization and the Wnt/b-catenin pathway activation.Additionally,we identified the E3 ligase neural precursor cell expressed developmentally downregulated 4-like(NEDD4L)as a modulator regulating the ubiquitination and degradation of AQP9.Conclusions:Collectively,our study revealed the important role of AQP9 in regulating DVL2 stabilization and Wnt/β-catenin signaling to promote CRC metastasis.Targeting the NEDD4L–AQP9–DVL2 axis might have therapeutic usefulness in metastatic CRC treatment. | Yiting Liu Qianling Gao Xingzhi Feng Guanxing Chen Xuefei Jiang Daici Chen Zihuan Yang | 2023 | Gastroenterology Report2023，11，1： | 0 |
| 5 | Dehydrogenation Based Asymmetric Epoxidation of Arylalkanes to Chiral Epoxides显示文摘We report herein a formal asymmetric epoxidation of arylalkanes enabled by a one-pot dual-catalysts system comprising a pincer Ir catalyst for alkane dehydrogenation-alkene isomerization(AD-ISO)and a chiral ketone catalyst for asymmetric alkene epoxidation.This protocol provides a catalytic method for the synthesis of aryl epoxides in useful yields with high regio-and stereoselectivity directly from readily available alkyl arenes.Stereospecific derivatizations of the epoxidation product allow access to various enantioenriched compounds. | Yiting Su Feng Yu Guixia Liu Zheng Huang | 2022 | Chinese Journal of Chemistry2022，40，19： | 0 |
| 6 | Damage quantitative assessment of spacecraft in a large-size inspection显示文摘To ensure the safety and reliability of spacecraft during multiple space missions,it is necessary to conduct in-situ nondestructive detection of the spacecraft to judge the damage caused by the hypervelocity impact of micrometeoroids and orbital debris(MMOD).In this paper,we propose an innovative quantitative assessment method based on damage reconstructed image mosaic technology.First,a Gaussian mixture model clustering algorithm is applied to extract images that highlight damage characteristics.Then,a mosaicking scheme based on the ORB feature extraction algorithm and an improved M-estimator SAmple Consensus(MSAC)algorithm with an adaptive threshold selection method is proposed which can create large-scale mosaicked images for damage detection.Eventually,to create the mosaicked images,the damage characteristic regions are segmented and extracted.The location of the damage area is determined and the degree of damage is judged by calculating the centroid position and the perimeter quantitative parameters.The efficiency and applicability of the proposed method are verified by the experimental results. | Kuo ZHANG Jianliang HUO Shengzhe WANG Xiao ZHANG Yiting FENG | 2022 | Frontiers of Information Technology & Electronic Engineering2022，23，4： | 0 |
| 7 | An Analysis of the English Translation of Chinese External Propaganda Texts in the Ecological Translation Perspective:A Case Study of the Written Speech“Harmony in Unity,Jointly Facing Challenges,Composing a New Chapter of Asia-Pacific Cooperation”显示文摘The paper,taking“Harmony in Unity,Jointly Facing Challenges,Composing a New Chapter of Asia-Pacific Cooperation”as the case,focuses on the English translation of Chinese external propaganda texts from the perspective of three-dimensions theory of ecological translation.The analysis aims to contribute to a better English version of the written speech and help achieve effective communication on the international stage,fostering a positive dissemination effect that enhances global understanding of China and,in turn,promotes internationally friendly exchanges and cooperation. | BAO Yiting CHEN Yu FENG Ya | 2024 | US-China Foreign Language2024，22，3： | 0 |
| 8 | Genetic and molecular exploration of maize environmental stress resilience:Toward sustainable agriculture显示文摘Global climate change exacerbates the effects of environmental stressors,such as drought,flooding,extreme temperatures,salinity,and alkalinity,on crop growth and grain yield,threatening the sustainability of the food supply.Maize(Zea mays)is one of the most widely cultivated crops and the most abundant grain crop in production worldwide.However,the stability of maize yield is highly dependent on environmental conditions.Recently,great progress has been made in understanding the molecular mechanisms underlying maize responses to environmental stresses and in developing stress-resilient varieties due to advances in high-throughput sequencing technologies,multi-omics analysis platforms,and automated phenotyping facilities.In this review,we summarize recent advances in dissecting the genetic factors and networks that contribute to maize abiotic stress tolerance through diverse strategies.We also discuss future challenges and opportunities for the development of climate-resilient maize varieties. | Zhirui Yang Yibo Cao Yiting Shi Feng Qin Caifu Jiang Shuhua Yang | 2023 | Molecular Plant2023，16，10： | 0 |
| 9 | Identification and validation of cardiac nonconserved human-specific enhancers显示文摘Congenital heart disease(CHD)is one of the most common causes of neonatal mortality.The worldwide morbidity of CHD is 9.410%o,while the proportion of CHD patients who are reported to carry mutations in coding regions is<50%.Enhancers play an important role in the spatio-temporal expression of target genes,and a lot of related variations are associated with CHD.There are conserved and nonconserved enhancers. | Yawen Zhang Yiting Gui Xudong Chen Feng Wang Fang Wu Youhua Wang Xu Wang Yonghao Gui Qiang Li | 2023 | Genes & Diseases2023，10，1： | 0 |
| 10 | Targeting macrophagic 17β-HSD7 by fenretinide for the treatment of nonalcoholic fatty liver disease显示文摘Nonalcoholic fatty liver disease(NAFLD)is the most common chronic liver disease worldwide and macrophage polarization plays an important role in its pathogenesis.However,which molecule regulates macrophage polarization in NAFLD remains unclear.Herein,we showed NAFLD mice exhibited increased 17β-hydroxysteroid dehydrogenase type 7(17β-HSD7)expression in hepatic macrophages concomitantly with elevated M1 polarization.Single-cell RNA sequencing on hepatic non-parenchymal cells isolated from wild-type littermates and macrophage-17β-HSD7 knockout mice fed with high fat diet(HFD)for 6 weeks revealed that lipid metabolism pathways were notably changed.Furthermore,17β-HSD7 deficiency in macrophages attenuated HFD-induced hepatic steatosis,insulin resistance and liver injury.Mechanistically,17β-HSD7 triggered NLRP3 inflammasome activation by increasing free cholesterol content,thereby promoting M1 polarization of macrophages and the secretion of pro-inflammatory cytokines.In addition,to help demonstrate that 17β-HSD7 is a potential drug target for NAFLD,fenretinide was screened out from an FDA-approved drug library based on its 17β-HSD7 dehydrogenase inhibitory activity.Fenretinide dose-dependently abrogated macrophage polarization and pro-inflammatory cytokines production,and subsequently inhibited fat deposition in hepatocytes co-cultured with macrophages.In conclusion,our findings suggest that blockade of 17β-HSD7 signaling by fenretinide would be a drug repurposing strategy for NAFLD treatment. | Xiaoyu Dong Yiting Feng Dongqin Xu Mengya Zhang Xiao Wen Wenhao Zhao Qintong Hu Qinyong Zhang Hui Fu Jie Ping | 2023 | Acta Pharmaceutica Sinica B2023，13，1： | 0 |
| 11 | Mo5+ doping induced interface polarization for improving performance of planar perovskite solar cells显示文摘In this paper,we investigate how interface-induced polarization affects the photovoltaic performance of hybrid perovskite solar cell(PSC)devices.The polarization of the hole transport layer(HTL)is regulated through incorporating metalliclike Mo Ox into PEDOT:PSS.The common Mo O3 doped into PEDOT:PSS is used as a reference,and the device that used PEDOT:PSS-Mo Ox as the HTL shows an enhanced Jsc and FF compared to the reference device.The open-circuit photovoltage decay and impedance spectroscopy measurements indicate that trap-assisted recombination is effectively suppressed at the interface between the hybrid perovskite and the PEDOT:PSS-Mo Ox HTL,while severe trap assisted recombination takes place at the perovskite/PEDOT:PSS and perovskite/PEDOT:PSS-Mo O3 interface.We attribute these experimental findings to the fact that the incorporation of metallic-like Mo5+into PEDOT:PSS enhances the conductivity of HTL and the interface polarization between PEDTOT:PSS layer and perovskite,which helps to induce an interface polarization electric field to facilitate separation of charges and screen the recombination between the traps and free charges. | Yurong Jiang Yue Yang Yiting Liu Shan Yan Yanxing Feng Congxin Xia | 2020 | Journal of Semiconductors2020，41，5： | 0 |
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