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| 1 | Radical Cation Diels-Alder Reactions of Non-Conjugated Alkenes as Dienophiles by Electrocatalysis显示文摘Radical cation Diels-Alder reactions provide a powerful method for the construction of six-membered ring systems between both electron-rich dienes and dienophiles. However, the most recent examples of this class have been limited to β-methylstyrenes as dienophiles;the use of non-conjugated alkenes remains challenging. The present study describes the serendipitous development of novel radical cation Diels-Alder reactions by electrocatalysis that use non-conjugated alkenes as dienophiles. The key to successful transformation involves highly substituted cyclohexenyl radical cations that are stable enough to be reduced by intermolecular single electron transfer. | Atsushi Ozaki Yusuke Yamaguchi Yohei Okada Kazuhiro Chiba | 2019 | Chinese Journal of Chemistry2019，37，6： | 1 |
| 2 | Effect of Intensive Rehabilitation on Physical Function and Arterial Function in Community-Dwelling Chronic Stroke Survivors显示文摘 | Katsuhiko Takatori Daisuke Matsumoto Yohei Okada Junji Nakamura Koji Shomoto | 2012 | Topics in Stroke Rehabilitation2012，，5： | 1 |
| 3 | Regulation of prostate-specific antigen by activin A in prostate cancer LNCaP cells显示文摘 | Yasuhisa Fujii Satoru Kawakami Yohei Okada | 2004 | Am J Physiol Endocrinol Metab2004，286，： | 1 |
| 4 | Initial 3-month dynamics of dehydroepiandrosterone sulfate can predict responsiveness to primary androgen deprivation therapy in patients with metastatic prostate cancer显示文摘Dear Editor,Intensive treatments such as primary androgen deprivation therapy(pADT)plus docetaxel or abiraterone acetate are reportedly beneficial in metastatic prostate cancer(mPCa)patients with high-volume disease or high-risk features,respectively.1,2 High-volume or high-risk features are determined exclusively via pretreatment parameters.Predicting patient responsiveness to pADT,which is one of the major determinants of survival in these patients,would be advantageous with regard to making primary treatment decisions.If an initial 3-month period is possible,short-term serum parameter dynamics can be used to predict pADT responsiveness.Prostate-specific antigen(PSA)and alkaline phosphatase(ALP)dynamics have been indicated as potential predictors.3,4 Although pADT can reportedly cause a 20%-30%decrease in adrenal androgen levels,5 it is not known whether the dynamics of adrenal androgens shortly after the initiation of pADT can predict pADT responsiveness.The aim of the current study was to identify predictors of pADT responsiveness among pretreatment parameters and 3-month dynamics(D3m)of serum parameters including the adrenal androgen,dehydroepiandrosterone sulfate(DHEAS). | Akihiro Yano Makoto Kagawa Hideki Takeshita Yohei Okada Makoto Morozumi Satoru Kawakami | 2019 | Asian Journal of Andrology2019，21，6： | 1 |
| 5 | Variation in the safety of induced pluripotent stem cell lines显示文摘 | Kyoko Miura Yohei Okada Takashi Ao | 2009 | NATURE BIOTECHNOLOGY2009，27，8： | 1 |
| 6 | Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells显示文摘 | Daisuke Taura Michio Noguchi Masakatsu Sone Kiminori Hosoda Eisaku Mori Yohei Okada Kazutoshi Takahashi Koichiro Homma Naofumi Oyamada Megumi Inuzuka Takuhiro Sonoyama Ken Ebihara Naohisa Tamura Hiroshi Itoh Hirofumi Suemori Norio Nakatsuji Hideyuki Okano | 2009 | FEBS Letters2009，，6： | 1 |
| 7 | A Novel Thermomorphic System for Electrocatalytic Diels-Alder Reactions显示文摘The discovery that lithium bis(trifluoromethane)sulfonamide (LiTFSI)/1-nitropropane (PrNO2) solution functions as a less polar alternative to lithium perchlorate (LiClO4)/nitromethane (MeNO2) solution has led to the development of a novel thermomorphic system for electrocatalytic Diels-Alder reactions. Methyl cyclohexane (Me-c-Hex) can form a monophasic condition with LiTFSI/PrNO2 solution at room temperature, enabling the use of hydrophobic dienophiles. After the electrochemical reaction, a biphasic condition can be formed at –50℃, where the cycloadducts are selectively recovered from the upper Me-c-Hex phase and the remaining lower LiTFSI/PrNO2 solution can be reused. | Yasushi Imada Naoki Shida Yohei Okada Kazuhiro Chiba | 2019 | Chinese Journal of Chemistry2019，37，6： | 0 |
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