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| 1 | Seasonal variation of snow microbial community structure in the East Rongbuk glacier, Mt. Everest显示文摘The bacterial diversity and abundance in the snow of East Rongbuk glacier, Mt. Everest were examined through 16S rRNA gene clone library and flow cytometry approaches. In total, 35 16S rRNA gene sequences were obtained, which belong to α, β, γ-Proteobacteria, Actinobacteria, Firmicutes, CFB, Cyanobacteria, Eukaryotic chloroplast, and TM7 candidate phylum respectively. γ-Proteobacteria was the dominant bacterial group in this region, while the genera Acinetobacter and Leclercia were domi- nant on the genus level. The community structure varied seasonally. The bacterial abundance in sum- mer snow was higher than that in winter. Moreover, the snow bacterial community structures in both seasons were diverse, with not only common species but season-specific species. The common species most likely originated from the Tibet Plateau. Bacteria in summer snow are affiliated with marine environ- ment, whereas bacteria in winter snow are closely related to more diverse environments and show the feature of resistance to cold. Seasonal variations of abundance and bacterial diversity were most proba- bly due to the seasonal characteristics of climate and atmospheric circulation in Mt. Everest. | LIU Yongqin YAO Tandong KANG Shichang JIAO Nianzhi ZENG Yonghui SHI Yang LUO Tingwei JING Zhefang HUANG Shijun | 2006 | Chinese Science Bulletin2006，51，12： | 7 |
| 2 | Integrated sensor system for monitoring rice growth conditions based on unmanned ground vehicle system显示文摘Ground-based platform systems provide a good tool for monitoring and managing crop conditions in precision agriculture applications and have been widely used for monitoring crop conditions.To develop an unmanned ground vehicle system(UGVS)based multi-sensors and test the feasibility of this system for monitoring rice conditions,an UGVS was developed to collect real-time rice condition information including NDVI values,reflectance measurements and crop canopy temperature in this study.Major components of the integrated system are GreenSeeker R100 system,hyper-spectroradiometer and infrared temperature sensor.The leaf area index(LAI)was measured by the CGMD302 Spectrometer.The Independent Samples T-Test method and the one way ANOVA method were used to determine the best spectral indices and analyze the relationship between the vegetation indices and rice LAI.It was found that the two best spectral indices for estimating LAI were NDVI(860 nm and 750 nm)with the correlation coefficient(R^(2))at 0.745 and RVI(853 nm and 751 nm)with the R^(2)at 0.724.The results show the UGVS can support multi-source information acquisition and is useful for crop management and precision agriculture applications. | Wang Pei Yubin Lan Luo Xiwen Zhou Zhiyan Zhigang Wang Yonghui Wang | 2014 | International Journal of Agricultural and Biological Engineering2014，7，2： | 6 |
| 3 | Enhancement of Aggression Induced by Isolation Rearing is Associated with a Lack of Central Serotonin显示文摘Isolation rearing(IR) enhances aggressive behavior, and the central serotonin(5-hydroxytryptamine,5-HT) system has been linked to IR-induced aggression.However, whether the alteration of central serotonin is the cause or consequence of enhanced aggression is still unknown. In the present study, using mice deficient in central serotonin Tph2-/-and Lmx1 b-/-, we examined the association between central serotonin and aggression with or without social isolation. We demonstrated that central serotonergic neurons are critical for the enhanced aggression after IR. 5-HT depletion in wild-type mice increased aggression. On the other hand, application of 5-HT in Lmx1 b-/-mice inhibited the enhancement of aggression under social isolation conditions. Dopamine was downregulated in Lmx1 b-/-mice. Similar to 5-HT, L-DOPA decreased aggression in Lmx1 b-/-mice. Our results linkthe serotoninergic system directly to aggression and this may have clinical implications for aggression-related human conditions. | Yiqiong Liu Yunong Sun Xiaoyan Zhao Ji-Young Kim Lu Luo Qian Wang Xiaolu Meng Yonghui Li Nan Sui Zhou-Feng Chen Chuxiong Pan Liang Li Yan Zhang | 2019 | Neuroscience Bulletin2019，35，5： | 5 |
| 4 | Microbial community structure in major habitats above 6000 m on Mount Everest显示文摘Bacterial abundance in surface snow between 6600 and 8000 m a.s.l. on the northern slope of Mt. Ev- erest was investigated by flow cytometry. Bacterial diversity in serac ice at 6000 m a.s.l., glacier melt- water at 6350 m, and surface snow at 6600 m a.s.l. was examined by constructing a 16S rRNA gene clone library. Bacterial abundance in snow was higher than that in the Antarctic but similar to other mountain regions in the world. Bacterial abundance in surface snow increased with altitude but showed no correlation with chemical parameters. Bacteria in the cryosphere on Mt. Everest were closely related to those isolated from soil, aquatic environments, plants, animals, humans and other frozen environ- ments. Bacterial community structures in major habitats above 6000 m were variable. The Cyto- phaga-Flavobacterium-Bacteroides (CFB) group absolutely dominated in glacial meltwater, while β-Proteobacteria and the CFB group dominated in serac ice, and β-Proteobacteria and Actinobacteria dominated in surface snow. The remarkable differences among the habitats were most likely due to the bacterial post-deposition changes during acclimation processes. | LIU YongQin YAO TanDong KANG ShiChang JIAO NianZhi ZENG YongHui HUANG SiJun LUO TingWei | 2007 | Chinese Science Bulletin2007，52，17： | 5 |
| 5 | Controllable synthesis of highly crystallized mesoporous TiO2/WO3 heterojunctions for acetone gas sensing显示文摘Mesoporous semiconducting metal oxides(SMOs)heterojunctions are appealing sensors for gas detecting.However,due to the different hydrolysis and condensation mechanism of every metal precursor and the contradiction between high crystallinity and high surface area,the synthesis of mesoporous SMOs heterojunctions with highly o rdered mesostructures,highly crystallized frameworks,and high surface area remains a huge challenge.In this work,we develop a novel'acid-base pair'adjusted solvent evaporation induced self-assembly(EISA)strategy to prepare highly crystallized ordered mesoporous TiO2/WO3(OM-TiO2/WO3)heterojunctions.The WCl6 and titanium isopropoxide(TIPO)are used as the precursors,respectively,which function as the'acid-base pair',enabling the coassembly with the structure directing agent(PEO-b-PS)into highly ordered meso structures.In addition,PEO-b-PS can be converted to rigid carbon which can protect the meso structures from collapse during the crystallization process.The resultant OM-TiO2/WO3 heterojunctions possess primitive cubic mesostructures,large pore size(~21.1 nm),highly crystalline frameworks and surface area(~98 m2/g).As a sensor for acetone,the obtained OM-TiO2/WO3 show excellent re sponse/recovery perfo rmance(3 s/5 s),good linear dependence,repeatability,selectivity,and long-term stability(35 days). | Changyao Wang Yuhui Li Pengpeng Qiu Linlin Duan Wei Bi Yan Chen Dingyi Guo Yupu Liu Wei Luo Yonghui Deng | 2020 | Chinese Chemical Letters2020，31，5： | 4 |
| 6 | General synthesis of hollow mesoporous conducting polymers by dual-colloid interface co-assembly for high-energy-density micro-supercapacitors显示文摘Rational design and precise regulation over the morphology, structure, and pore size of functional conducting mesoporous polymers with enriched active sites and shorten electron–ion transport pathway are extremely important for developing high-performance micro-supercapacitors (MSCs), but still remain a great challenge. Herein, a general dual-colloid interface co-assembly strategy is proposed to fabricate hollow mesoporous polypyrrole nano-bowls (mPPy-nbs) for high-energy-density solid-state planar MSCs. By simply adjusting the size of block copolymer micelles, the diameter of polystyrene nanospheres and the amount of pyrrole monomer, mesopore size of the shell, void and shell thickness of mPPy-nbs can be simultaneously controlled. Importantly, this strategy can be further utilized to synthesize other hollow mesoporous polymers, including poly(tris(4-aminophenyl)amine), poly(1,3,5-triaminobenzene) and their copolymers, demonstrative of excellent universality. The structurally optimized mPPy-nb exhibits high specific surface area of 122 m^(2) g^(−1)and large capacitance of 225 F g^(−1) at 1 mV s^(−1). Furthermore, the MSCs assembled by mPPy-nbs deliver impressive volumetric capacitance of 90 F cm^(−3) and energy density of 2.0 mWh cm^(−3), superior to the most reported polymers-based MSCs. Also, the fabricated MSCs present excellent flexibility with almost no capacitance decay under varying bending states, and robust serial/parallel self-integration for boosting voltage and capacitance output. Therefore, this work will inspire the new design of mesoporous conducting polymer materials toward high-performance microscale supercapacitive devices. | Jing Cui Fei-Fei Xing Hao Luo Jie-Qiong Qin Yan Li Yonghui Zhong Facai Wei Jianwei Fu Chengbin Jing Jiangong Cheng Zhong-Shuai Wu Shaohua Liu | 2021 | Journal of Energy Chemistry2021，30，11： | 3 |
| 7 | Genetic architecture of maize yield traits dissected by QTL mapping and GWAS in maize显示文摘The study of yield traits can reveal the genetic architecture of grain yield for improving maize production.In this study, an association panel comprising 362 inbred lines and a recombinant inbred line population derived from X178 × 9782 were used to identify candidate genes for nine yield traits. High-priority overlap(HPO) genes, which are genes prioritized in a genome-wide association study(GWAS), were investigated using coexpression networks. The GWAS identified 51 environmentally stable SNPs in two environments and 36 pleiotropic SNPs, including three SNPs with both attributes. Seven hotspots containing 41 trait-associated SNPs were identified on six chromosomes by permutation. Pyramiding of superior alleles showed a highly positive effect on all traits, and the phenotypic values of ear diameter and ear weight consistently corresponded with the number of superior alleles in tropical and temperate germplasm. A total of 61 HPO genes were detected after trait-associated SNPs were combined with the coexpression networks. Linkage mapping identified 16 environmentally stable and 16 pleiotropic QTL.Seven SNPs that were located in QTL intervals were assigned as consensus SNPs for the yield traits.Among the candidate genes predicted by our study, some genes were confirmed to function in seed development. The gene Zm00001 d016656 encoding a serine/threonine protein kinase was associated with five different traits across multiple environments. Some genes were uniquely expressed in specific tissues and at certain stages of seed development. These findings will provide genetic information and resources for molecular breeding of maize grain yield. | Xiao Zhang Zhiyong Ren Bowen Luo Haixu Zhong Peng Ma Hongkai Zhang Hongmei Hu Yikai Wang Haiying Zhang Dan Liu Ling Wu Zhi Nie Yonghui Zhu Wenzhu He Suzhi Zhang Shunzong Su Yaou Shen Shibin Gao | 2022 | The Crop Journal2022，10，2： | 2 |
| 8 | Dynamics of local extreme rainfall of super Typhoon Soudelor (2015) in East China显示文摘The characteristics and dynamics associated with the distribution, intensity, and triggering factors of local severe precipitation in Zhejiang Province induced by Super Typhoon Soudelor(2015) were investigated using mesoscale surface observations, radar reflectivity, satellite nephograms, and the final(FNL) analyses of the Global Forecasting System(GFS) of the National Center for Environmental Prediction(NCEP). The rainfall processes during Soudelor's landfall and translation over East China could be separated into four stages based on rainfall characteristics such as distribution, intensity, and corresponding dynamics. The relatively less precipitation in the first stage resulted from interaction between the easterly wind to the north flank of this tropical cyclone(TC) and the coastal topography along the southeast of Zhejiang Province, China. With landfall of the TC in East China during the second stage, precipitation maxima occurred because of interaction between the TC's principal rainbands and the local topography from northeastern Fujian Province to southwestern Zhejiang Province. The distribution of precipitation presented significant asymmetric features in the third stage with maximal rainfall bands in the northeast quadrant of the TC when Soudelor's track turned from westward to northward as the TC decayed rapidly. Finally, during the northward to northeastward translation of the TC in the fourth stage, the interaction between a mid-latitude weather system and the northern part of the TC resulted in transfer of the maximum rainfall from the north of Zhejiang Province to the north of Jiangsu Province,which represented the end of rainfall in Zhejiang Province. Further quantitative calculations of the rainfall rate induced by the interaction between local topography and TC circulation(defined as 'orographic effects') in the context of a one-dimensional simplified model showed that orographic effects were the primary factor determining the intensity of precipitation in this case,and accounted for over 50% of the total precipitation. The asymmetric distribution of the TC's rainbands was closely related to the asymmetric distribution of moisture resulted from changes of the TC's structure, and led to asymmetric distribution of local intense precipitation induced by Soudelor. Based on analysis of this TC, it could be concluded that local severe rainfall in the coastal regions of East China is closely related to changes of TC structure and intensity, as well as the outer rainbands. In addition, precipitation intensity and duration will increase correspondingly because of the complex interactions between the TC and local topography, and the particular TC track along large-scale steering flow. The results of this study may be useful for the understanding, prediction, and warning of disasters induced by local extreme rainfall caused by TCs, especially for facilitating forecasting and warning of flooding and mudslides associated with torrential rain caused by interactions between landfalling TCs and coastal topography. | Jinsong PAN Daigao TENG Fuqing ZHANG Lingli ZHOU Ling LUO Yonghui WENG Yunji ZHANG | 2018 | Science China Earth Sciences2018，61，5： | 1 |
| 9 | Cation exchange hybrid membranes based on PVA for alkali recovery through diffusion dialysis显示文摘 | Hui Wang Cuiming Wu Yonghui Wu Jingyi Luo Tongwen Xu | 2011 | Journal of Membrane Science2011，，1： | 1 |
| 10 | 显示文摘 | Jingyi Luo Cuiming Wu Yonghui Wu | 2010 | Journal of Membrane Science2010，，347： | 1 |
| 11 | A novel oscillator based on heterogeneous carbon@ MoS2 nanotubes显示文摘新奇异构的振荡器的摆动的行为碳创作了,铝二硫化物 nanotubes (CNT@MST ) 第一次被调查,由使用古典分子的动力学的方法。在建议振荡器,铝二硫化物 nanotube (山区标准时间) 被放作为一个外部试管,导致与半导体工业标准的更好的相容性。有到达 20 GHz 的频率的一个光滑、稳定的振荡器为大量差距宽度基于双 walled CNT@MST hetero-nanotube 被获得,显示建议振荡器比从双 walled 碳 nanotubes (CNT ) 造的那些更好表现要求差距宽度的一个狭窄的范围。另外,包含不同内部、外部的试管 chirality 的 CNT@MST 振荡器的摆动特征比与一样的 chirality 包含二个试管的 CNT@MST 振荡器的那些显著地好。 | Wugui Jiang Yonghui Zeng Qinghua Qin Qianghui Luo | 2016 | Nano Research2016，9，6： | 1 |
| 12 | Anisotropy of thermal conductivity and mechanical properties in Mg–5Zn–1Mn alloy显示文摘 | Jiawei Yuan Kui Zhang Ting Li Xinggang Li Yongjun Li Minglong Ma Ping Luo Guangqiu Luo Yonghui Hao | 2012 | Materials and Design2012，，： | 1 |
| 13 | Vaccination of Goats with 31 kDa and 32 kDa Schistosoma japonicum Antigens by DNA Priming and Protein Boosting显示文摘Two Schistosoma japonicum vaccine candidate antigens Sj 31 and Sj 32, which have shown particular promise to induce protective immunity in mice, were used to immunize goats by using a DNA priming-protein boosting strategy in present work. DNA vaccine formulations of the two antigens (VRSj31 and VRSj32) were produced and injected intramuscularly twice at a 2-week interval and then recombinant proteins (rSj31 and rSj32) together with Freund Complete Adjuvant (FCA) were used to boost the goats. The experiment was repeated in different batche cercariae. A strong anamnestic antibody response was induced after boost. A significant reduction of liver egg counts and miracidial hatching was showed in both experiments. Significant protections against challenge infection were elicited with 31.6% of percentage reduction for worm recovery in the second experiment and 20.9% in the first experiment, respectively. | Lianfei Tang Zhijun Zhou Yuxiao Chen Yonghui Luo Linqian Wang Liyu Chen Fushen Huang Xianfang Zeng Xinyuan Yi | 2007 | Cellular & Molecular Immunology2007，4，2： | 1 |
| 14 | Social crowding sensitizes high-responding rats to psychomotor stimulant effects of morphine显示文摘 | Zheng Xigeng Li Yonghui Luo Xiaojing | 2004 | Pharmacol Biochem Behav2004，79，2： | 1 |
| 15 | Diffusion dialysis of hydrochloride acid at different temperatures using PPO- SiO2 hybrid anion exchange membranes 显示文摘 | Luo Jingyi Wu Cuiming Wu Yonghui | 2010 | J Membr Sci2010，347，： | 1 |
| 16 | Diffu- sion dialysis of hydrochloric acid with their salts: Effect of co-existence metal ions显示文摘 | Luo Jingyi Wu Cuiming Wu Yonghui | 2013 | Sep Purif Techn- ol2013，118，： | 1 |
| 17 | Eupalinolide B inhibits hepatic carcinoma by inducing ferroptosis and ROS-ER-JNK pathway显示文摘Primary hepatic carcinoma is a common malignant tumor.The classic molecular targeted drug sorafenib is costly and is only effective for some patients.Therefore,it is of great clinical significance to search for new molecular targeted drugs.Eupalinolide B(EB)from Eupatorium lindleyanum DC.is used to treat chronic tracheitis in clinical practice.However,the role of EB in hepatic carcinoma is unknown.In this study,we first measure the effect of EB on tumor growth in a xenograft model and PDX model.The cell proliferation and migration are also detected in human hepatocarcinoma cell lines(SMMC-7721 and HCCLM3).Then,we investigate cell cycle,cell apoptosis,cell necrosis,cell autophagy,and ferroptosis by flow cytometry,western blot analysis and electron microscopy.The results demonstrate that EB exerts anti-proliferative activity in hepatic carcinoma by blocking cell cycle arrest at S phase and inducing ferroptosis mediated by endoplasmic reticulum(ER)stress,as well as HO-1 activation.When HO-1 is inhibited,EB-induced cell death and ER protein expression are rescued.The migration-related mechanism consists of activation of the ROS-ER-JNK signaling pathway and is not connected to ferroptosis.In summary,we first discover that EB inhibits cell proliferation and migration in hepatic carcinoma,and thus EB is a promising anti-tumor compound that can be used for hepatic carcinoma. | Yonghui Zhang Haoyang Zhang Jinage Mu Meiyue Han Zhihao Cao Feng Dong Tingting Wang Lian Pan Wujing Luo Jiaxin Li Huan Liu Lishan Jin Wenxuan Ding Yong Wei Xuesong Deng Dan Liu Xiuzhen He Yi Pang Xiao Mu Zhongjun Wu Dilong Chen | 2022 | Acta Biochimica et Biophysica Sinica2022，54，7： | 1 |
| 18 | Diffusion dialysis-concept, principle and applications显示文摘 | Jingyi Luo Cuiming Wu Tongwen Xu Yonghui Wu | 2010 | Journal of Membrane Science2010，，1： | 1 |
| 19 | Undescribed Meroterpenoids from Hypericum japonicum with Neuroprotective Effects on H_(2)O_(2) Insult SH-SY5Y Cells Targeting Keap1-Nrf2显示文摘Unreported tautomeric/enantiomeric meroterpenoids,(±)-hyperjaponols I—K(1-3),were discovered from Hypericum japonicum.Comprehensive chemical investigations established the absolute characteristics of these stereoisomers.The TS calculation demon-strated that 1a and 2a easily occur enol-keto tautomerism with steady configurations individually.Amongst isolates,1b showed the strongest neuroprotective activity with the concentration at 25μmol/L on H_(2)O_(2) insult SH-SY5Y cells.In vitro molecular biological ex-periments manifested that 1b activated the Keap1-Nrf2-ARE pathway,leading to the promotion of Nrf2 nuclear translocation,down-regulation of the expression level of Keap1,and upregulation of the levels of Nrf2,NQO-1,and HO-1.The results of in silico simulation showed that 1b possessed good binding features with Keap1(5FNQ)via forming multiple typical hydrogen and hydrophobic bonds as well as less fluctuation of RMSD and RMSF during a natural physiological condition. | Linzhen Hu Zhenzhen Wang Zhou Tong Ping Hu Luqi Kong Mengying Luo Xiao-Nian Li Yuexing Zhang Zhiyong Huang Yonghui zhang | 2022 | Chinese Journal of Chemistry2022，40，11： | 1 |
| 20 | Amphiphilic block copolymers directed synthesis of mesoporous nickel-based oxides with bimodal mesopores and nanocrystal-assembled walls显示文摘Mesoporous late-transition metal oxides have great potential in applications of energy,catalysis and chemical sensing due to their unique physical and chemical properties.However,their synthesis via the flexible and scalable soft-template method remain a great challenge,due to the weak organic-inorganic interaction between the frequently used surfactants(e.g.,Pluronic-type block copolymers) and metal oxide precursors,and the low crystallization temperature of metal oxides.In this study,ordered mesoporous NiO with dual mesopores,high surface area and well-interconnected crystalline porous frameworks have been successfully synthesized via the facile solvent evaporation-induced co-assembly(EICA) method,by using lab-made amphiphilic diblock copolymer polystyrene-b-poly(4-vinylpyridine)(PS-b-P4 VP) as both the structure-directing agent(the soft template) and macromolecular chelating agents for nickel species,THF as the solvent,and nickel acetylacetonate(Ni(acac)2) as inorganic precursor.Similarly,by using Ni(acac)2 and Fe(acac)3 as the binary precursors,ordered mesoporous Fedoped NiO materials can be obtained,which have bimodal mesopores of large mesopores(32.5 nm) and secondary mesopores(4.0-11.5 nm) in the nanocrystal-assembled walls,high specific surface areas(~74.8 m^2/g) and large pore value(~0.167 cm^3/g).The obtained mesoporous Fe-doped NiO based gas sensor showed superior ethanol sensing performances with good sensitivity,high selectivity and fast response-recovery dynamics. | Yuan Ren Xuanyu Yang Xinran Zhou Wei Luo Yi Zhang Xiaowei Cheng Yonghui Deng | 2019 | Chinese Chemical Letters2019，30，12： | 0 |
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