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| 1 | Utilization of longitudinal ultrasound to quantify joint soft-tissue changes in a mouse model of posttraumatic osteoarthritis显示文摘To assess the utility of longitudinal ultrasound(US) to quantify volumetric changes in joint soft tissues during the progression of posttraumatic osteoarthritis(PTOA) in mice, and validate the US results with histological findings. A longitudinal cohort of 3-month-old wild-type C57 BL/6 male mice received the Hulth-Telhag surgical procedure on right knee to induce PTOA, and sham surgery on their left knee as control. US scans were performed on both knees before, 2, 4, 6, and 8 weeks post-surgery. Joint space volume and Power-Doppler(PD) volume were obtained from US images via Amira software. A parallel cross-sectional cohort of mice was killed at each US time point, and knee joints were subjected to histological analysis to obtain synovial soft-tissue area and OARSI scores. The correlation between US joint space volume and histological synovial soft-tissue area or OARSI score was assessed via linear regression analysis. US images indicated increased joint space volume in PTOA joints over time, which was associated with synovial inflammation and cartilage damage by histology. These changes started from 2 weeks post-surgery and gradually became more severe. No change was detected in sham joints. Increased joint space volume was significantly correlated with increased synovial soft-tissue area and the OARSI score(P o 0.001). PD signal was detected in the joint space of PTOA joints at 6 weeks post-surgery, which was consistent with the location of blood vessels that stained positively for CD31 and alpha-smooth muscle actin in the synovium.This study indicates that US is a cost-effective longitudinal outcome measure of volumetric and vascular changes in joint soft tissues during PTOA progression in mice, which positively correlates with synovial inflammation and cartilage damage. | Hao Xu Echoe M Bouta Ronald W Wood Edward M Schwarz Yongjun Wang Lianping Xing | 2017 | Bone Research2017，5，3： | 7 |
| 2 | Electrical pro- perties of SnO2-ZnO-Nb2O3 varistor system显示文摘 | Yongjun W Jinfeng W Hongcun C | 2000 | J Phys D: Appl Phys2000，33，： | 1 |
| 3 | Cervical intervertebral disc degenera- tion induced by unbalanced dynamic and static forces:a novel in vivo rat model显示文摘 | Yongjun W Qi S Lu W | 2006 | Spine2006，31，： | 1 |
| 4 | Low hematocrit worsens cerebral injury after prolonged hypothermic circulatory arrest inrats显示文摘 | Dian-San S Xiang-Rui W Yongjun Z | 2006 | Can JAnaeth2006，53，12： | 1 |
| 5 | Chinese guidelines for the see- ondary prevention of ischemic stroke and transient ischemic attack 2010显示文摘 | Yongjun W Suming Z Liqun Z | 2012 | CNS Neurosc Therapeut2012，18，2： | 1 |
| 6 | Differential expression of perforin in cytotoxic lymphocyte in HIV/AIDS patients of China 显示文摘 | Qi W Yongjun J Yanan W | 2006 | J Clin Immunol2006，26，4： | 1 |
| 7 | Electrochemical behaviors of anodized magnesium ahoy AZ91D in chloride containing aqueous solution 显示文摘 | Yongjun Z Chuanwei Y Fuhui W | 2005 | Corrosion Science2005，11，： | 1 |
| 8 | Interaction of Clay Min- erals in Copper-gold Flotation:Part2-Influence of Some Cal- cium Bearing Gangue Minerals on the Rheological Behavior 显示文摘 | CRUZ N PENG Yongjun ELAINE W | 2015 | International Journal of Mineral Processing2015，141，： | 1 |
| 9 | A review of mechanical drilling for composite laminates review article 显示文摘 | Liu Defu Tang Yongjun ('ng W L | 2012 | Composite Structures2012，94，4： | 1 |
| 10 | Cervical intervertebral disc degeneration induced by unbalanced dynamic and static forces:a novel in vivo rat model显示文摘 | Yongjun W Qi S Lu W | 2006 | Spine2006，31，10： | 1 |
| 11 | Color Image Processing Pipeline显示文摘 | Ramanath R Snydcr W E Yongjun Yoo | 2005 | IEEE Signal Processing Magazine2005，2，1： | 1 |
| 12 | Reliability and validity of a Chinese version of the Quality of Life in Epilepsy Inventory (QOLIE-89) 显示文摘 | YONGQING Z H CHENGYUN D YONGJUN W | 2007 | Epilepsy & Behavior2007，11，： | 1 |
| 13 | Brand Commitment in Consumer-brand Relationships: An Investment Model Approach显示文摘 | Sung Yongjun Campbell W K | 2009 | Journal of Brand Management2009，17，2： | 1 |
| 14 | Signal processing-based direction finder for transient capacitor switching disturbances显示文摘 | Shin YongJune Powers E J Grady W M | 2008 | IEEE Trans on Power Delivery2008，23，4： | 1 |
| 15 | COMPUTATION OF STRESS INTENSITY FACTORS BY THE SUB-REGION MIXED FINITE ELEMENT METHOD OF LINES显示文摘把概括变化原则基于分区,一个分区混合了“线的最新开发的半分析的有限元素方法(FEMOL ) ”的版本为二维的槽口 / 裂缝的压力紧张因素(SIF ) 的精确、有效的计算在这篇论文被建议。包围槽口 / 裂缝尖端的圆形的区域作为压力的单个解决方案的很多个领先的术语在被使用的互补精力区域被拿,与在未知系数之中的寻求的 SIF。任意的领域的休息作为 FEMOL 在被使用获得近似排水量的势能区域被进行。平常的微分方程(颂诗) 和代数学的方程的一个混合系统经由分区被导出概括变化原则。最后从混合方程系统消除压力参数的一种奇特移动技术产出一个标准 FEMOL 颂诗系统,其解决方案不再单个并且简单地并且高效地用一个标准通用颂诗解答者被获得。包括在反飞机和飞机弹性的双性人材料槽口 / 裂缝,很多个数字例子被给显示出建议方法的通常优秀的表演。 | Yuan Si Xu Yongjun WILLIAMS F W | 2007 | Acta Mechanica Solida Sinica2007，20，2： | 0 |
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