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| 1 | Role of microbial dysbiosis in the pathogenesis of esophageal mucosal disease:A paradigm shift from acid to bacteria?显示文摘Genomic sequencing,bioinformatics,and initial speciation(e.g.,relative abundance)of the commensal microbiome have revolutionized the way we think about the“human”body in health and disease.The interactions between the gut bacteria and the immune system of the host play a key role in the pathogenesis of gastrointestinal diseases,including those impacting the esophagus.Although relatively stable,there are a number of factors that may disrupt the delicate balance between the luminal esophageal microbiome(EM)and the host.These changes are thought to be a product of age,diet,antibiotic and other medication use,oral hygiene,smoking,and/or expression of antibiotic products(bacteriocins)by other flora.These effects may lead to persistent dysbiosis which in turn increases the risk of local inflammation,systemic inflammation,and ultimately disease progression.Research has suggested that the etiology of gastroesophageal reflux disease-related esophagitis includes a cytokine-mediated inflammatory component and is,therefore,not merely the result of esophageal mucosal exposure to corrosives(i.e.,acid).Emerging evidence also suggests that the EM plays a major role in the pathogenesis of disease by inciting an immunogenic response which ultimately propagates the inflammatory cascade.Here,we discuss the potential role for manipulating the EM as a therapeutic option for treating the root cause of various esophageal disease rather than just providing symptomatic relief(i.e.,acid suppression). | Steve M D'Souza Kevin Houston Lauren Keenan Byung Soo Yoo Parth J Parekh David A Johnson | 2021 | World Journal of Gastroenterology2021，27，18： | 8 |
| 2 | The Impact of Marketing - induced Versus Word - of - mouth Customer Acquisition on Customer Equity Growth 显示文摘 | Villanueva J Yoo S Hanssens D M | 2008 | Journal of Marketing Research2008，45，1： | 1 |
| 3 | Design and operation consid-erations for wastewater treatment of municipal wastewater显示文摘 | Shim J K Yoo I K Lee Y M | 2002 | Water Research2002，36，： | 1 |
| 4 | A cost - efficient WDM - PON architecture supporting dynamic wavelength and time slot allocation显示文摘 | Kim H Hwang J Yoo M | 2007 | ICACT2007，，3： | 1 |
| 5 | Greater and lesser omenta: normal anatomy and pathologic processes 显示文摘 | Yoo E Kim J H Kim M J | 2007 | Radiographics2007，27，3： | 1 |
| 6 | Phylogeny and diversificatoin of B-function MADS-box genes in angiosperms: Evolutionary and functional implications of a 260-million-year-old duplication显示文摘 | Kim S Yoo M J Albert V A | 2004 | Am J Bot2004，91，： | 1 |
| 7 | Doppler shift spectroscopy for the measurement of angular divergence and ion species of ion beam 显示文摘 | Yoo S J YANG H L HWANG S M | 1999 | Journal of the Korean Physics Society1999，35，： | 1 |
| 8 | Nonbasal deformation modes of HCP metals and alloys: Role of dislocation source and mobility显示文摘 | Yoo M H Morris J R Ho K M | 2002 | Metall Mater Trans2002，33，： | 1 |
| 9 | Statistical process monitoring with independent component analysis显示文摘 | Lee J M Yoo C K Lee I B | 2004 | Journal of Process Control2004，14，： | 1 |
| 10 | Selection of microalgae for lipid production under high levels carbon dioxide 显示文摘 | YOO C JUN S Y LEE J Y AHN C Y OH H M | 2010 | Bioresoure Technology2010，101，1： | 1 |
| 11 | Stability characteristics of Pt1Ni1/C as cathode catalysts in membrane electrode assembly of polymer electrolyte membrane fuel cell显示文摘 | CHO Y H JEON T Y YOO S J LEE K S AHN M KIM O H CHO Y H LIM J W JUNG N YOON W S CHOE H SUNG Y E | 2012 | Electrochim Acta2012，59，： | 1 |
| 12 | 查看详情显示文摘 | Kim S D Baek S C Lee Y J Jun K W Kim M J Yoo I S | | 0，，： | 1 |
| 13 | Incidence of dysphagia after anterior cervical spine surgery: a prospective study显示文摘 | Bazaz R Lee M J Yoo JU | 2002 | Spine2002，27，22： | 1 |
| 14 | The control of neural cell-to-cell interactions through non- contact electrical field stimulation using graphene electrodes显示文摘 | Heo C Yoo J Lee S Jo A Jung S Yoo H Lee Y H Suh M | 2011 | Biomaterials2011，32，： | 1 |
| 15 | Properties of textured ZnO:A1 films prepared by RF magnetron sputtering for thin film solar cells显示文摘 | Yoo J Dhungel S K Gowtham M | 2005 | Journal of the Korean Physical Society2005，47，： | 1 |
| 16 | Risk factors for postoperative ile- us after urologic laparoscopic surgery 显示文摘 | Kim M J Min GE Yoo KH | 2011 | J Korean Surg Soc2011，80，6： | 1 |
| 17 | Oxidative stress regulated genes in nigral dopaminergic neuronal cells: correlation with the known pathology in Parkinson' s disease 显示文摘 | Yoo M S Chun H S Son J J | 2003 | Brain Res Mol Brain Res2003，110，1： | 1 |
| 18 | Selection of twenty-four highly informative SNP markers for human identification and paternity analysis in Koreans显示文摘 | LEE H Y PARK M J YOO J E | 2005 | Forensic Sci Int2005，148，23： | 1 |
| 19 | Transfection of differentiated human hepatoms cell line (Huh7) with in vitro - transcribed hepatitis C virus of (HCV)RAN and establishment of a long tern culture persistently in fected with HCV 显示文摘 | Yoo B J Selby M J Choe J | 1995 | Virol1995，69，1： | 1 |
| 20 | Nonlinear Process Monitoring Using Kernel Principal Component Analysis 显示文摘 | LEE J M YOO C K CHOI S W | 2004 | Chemical Engineering Science2004，59，： | 1 |
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