| 1 | Involvement of Ghrelin-Growth Hormone Secretagogue Receptor System in Pathoclinical Profiles of Digestive System Cancer显示文摘Ghrelin 受体被显示了沿着人的胃肠的道被表示。最近的研究证明 ghrelin 和合成 ghrelin 受体收缩筋改进了重量获得和瘦身体质量在由对 ghrelin 受体起作用的癌症极度瘦弱的一个老鼠模型的保留,也就是说生长荷尔蒙促泌素受体(GHS-R ) 。这研究试图在人的胃肠的道癌症探索表示和 ghrelin 受体的分发并且在人的消化癌症调查 ghrelin-GHS-R 系统的可能的参与。外科的人的消化癌症标本从不同病人从胃肠的道的各种各样的部分被获得。在这些纸巾的 ghrelin 受体的表达式被织物检测微数组技术。我们的结果证明那 ghrelin 受体在整个胃肠的道在癌症被表示,主要在 mucosal 层房间的细胞质。它的表示水平可能与病人的机关类型,组织学的等级, tumor-nodes-metastases 阶段,和营养地位(重量损失) 相关。第一次,我们在消化系统癌症识别了 ghrelin 受体的分发。我们的结果暗示 ghrelin-GHS-R 系统可能涉及消化癌症的 pathoclinical 侧面。 | Zhigang WANG Weigang WANG Wencai QIU Youben FAN Jun ZHAO Yu WANG Qi ZHENG | 2007 | Acta Biochimica et Biophysica Sinica2007，39，12： | 3 |
| 2 | Identification and profile of phenolamides with anthracnose resistance potential in tea(Camellia sinensis)显示文摘Tea anthracnose is a prevalent disease in China that can lead to reduced tea production and lower quality,yet there is currently a lack of effective means for controlling this disease.In this study,we identified 46 phenolamides(including 27 isomers)in different tissues and organs of tea plants based on a developed workflow,and the secondary mass spectra of all these compounds have been documented.It was revealed that tea plants predominantly accumulate protonated aliphatic phenolamides,rather than aromatic phenolamides.The profile of phenolamides indicate that their buildup in tea plants is specific to certain tissues and acyl-acceptors,and this distribution is associated with the extent of phenolamide acyl-modification.Additionally,it was observed that N-Feruloylputrescine(Fer-Put,a type of phenolamides)was responsive to the stimulated accumulation of the tea anthracnose pathogen.The findings of anti-anthracnose experiments in vitro and on tea leaf demonstrated that Fer-Put was capable of significantly inhibiting the growth of anthracnose pathogen colony,effectively prevented tea leaf disease.Furthermore,it was observed that Fer-Put treatment can enhance the antioxidant enzyme activity of tea leaves.TEA002780.1 and TEA013165.1 gene may be responsible for the biosynthesis of Fer-Put in the disease resistance process in tea plants.Through these studies,the types and distribution of phenolamides in tea plants have been elucidated,and Fer-Put’s ability to resist anthracnose has been established,providing new insights into the resistance of tea anthracnose. | Wenzhao Wang Xingcui Xie Yuanyuan Lv Haonan Guan Lu Liu Qian Huang Yumeng Bao Jie Zhou Lu Bao Chunmei Gong Youben Yu | 2023 | Horticulture Research2023，10，9： | 0 |
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