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| 1 | Automatic generation of cutting tool path upon freeform surfaces显示文摘 | Yu Daoyuan Duan Zhengcheng | 1993 | Materials and Processing Technology1993，36，4： | 1 |
| 2 | Generation of Gouge-free Cutter Location Paths on Freeform Surface for Non-spherical Cutters显示文摘 | Yu Daoyuan Deng Jianchun Duan Zhengcheng | 1996 | Computer in Industry1996，28，： | 1 |
| 3 | An improved reduction algorithm based on the degree of attribute discernibility显示文摘 | 张铮 Yu Daoyuan Li Peigen | 2007 | High Technology Letters2007，13，3： | 1 |
| 4 | Isogeometric Analysis and Shape Optimization of Holed Structures via the Patch Removing Technique显示文摘In this study,a patch removing based Isogeometric analysis(PR-IGA)method is proposed to conduct the holed structural analysis with only one parametric domain,in which there are also no trimmed elements.The theoretical foundation of this novel patch removing approach is that any holed structure can be obtained by removing sub-patches(i.e.,the holes)from an intact base patch.Since the parametric domains of these patches are all meshed by rectangular grids,the elements in the resulted holed structural parametric domain could all be untrimmed rectangles under certain mapping conditions.To achieve the special condition,a systematic technique consisting of T-spline local refinement and control points substitution/adjustment is provided.Due to the intactness of parametric elements,the analysis procedure of holed structures based on the proposed PRIGA is quite simplified and efficient compared to traditional multi-patch and trimming schemes.Moreover,after the deduction of analytical sensitivities related to structural mass and mechanical responses,the PR-IGA is directly employed in the holed structural shape optimization to successfully eliminate the need for model transformation during modeling,analysis and optimization processes.Numerical examples involving analysis and shape optimization of complex holed structures are presented to demonstrate the effectiveness of the proposed method. | Daoyuan Yu Shouyu Cai Wenya Fan Lan Zhang | 2020 | Computer Modeling in Engineering & Sciences2020，，9： | 1 |
| 5 | Automatic generation of cutting tool path upon freeform surfaces 显示文摘 | Yu Daoyuan Duan Zhengcheng | 1993 | Materials Processing Technology1993，36，4： | 1 |
| 6 | Single-nucleus profiling unveils a geroprotective role of the Foxo3 in primate skeletal muscle aging显示文摘Age-dependent loss of skeletal muscle mass and function is a feature of sarcopenia,and increases the risk of many aging-related metabolic diseases.Here,we report phenotypic and single-nucleus transcriptomic analyses of non-human primate skeletal muscle aging.A higher transcriptional fluctuation was observed in myonuclei relative to other interstitial cell types,indicating a higher susceptibility of skeletal muscle fiber to aging.We found a downregulation of Foxo3 in aged primate skeletal muscle,and identi-fied FOxo3 as a hub transcription factor maintaining skeletal muscle homeostasis.Through the establishment of a complementary experimental pipeline based on a human pluripotent stem cell-derived myotube model,we revealed that silence of Foxo3 accelerates human myotube senescence,whereas genetic activation of endogenous FOxO3 alleviates human myotube aging.Altogether,based on a combination of monkey skeletal muscle and human myotube aging research models,we unraveled the pivotal role of the FOxO3 in safeguarding primate skeletal muscle from aging,providing a comprehensive resource for the development of clinical diagnosis and targeted therapeutic interventions against human skeletal muscle aging and the onset of sarcopenia along with aging-relateddisorders. | Ying Jing Yuesheng Zuo Yang Yu Liang Sun Zhengrong Yu Shuai Ma Qian Zhao Guoqiang Sun Huifang Hu Jingyi Li Daoyuan Huang Lixiao Liu Jiaming Li Zijuan Xin Haoyan Huang Juan Carlos Izpisua Belmonte Weiqi Zhang Si Wang Jing Qu Guang-Hui Liu | 2023 | Protein & Cell2023，14，7： | 0 |
| 7 | FTO stabilizes MIS12 and counteracts senescence显示文摘Dear Editor, N6-methyladenosine(m6A)is an abundant epitranscriptomic modification that regulates messenger RNA(mRNA)biology.The m6A modification regulates mRNA splicing,transport,stability,and translation through coordinated activities by methyltransferases(writers),binding proteins(readers),and demethylases(erasers)(Huang et al.,2020;Wu et al.,2020).Among m6A regulators,fat mass of obesity-associ-ated protein(FTO),is the first discovered eraser with RNA m6A demethylation activity(Jia et al.,2011).Since then,FTO has been reported to play m6A-dependent roles in a variety of physiological processes including adipogenesis,neuro-genesis and tumorigenesis(Fischer et al.,2009;Li et al.,2017;Huang et al.,2020).Consequently,FTO deficiency in mice leads to dramatic phenotypes,such as decreased fat mass and impaired brain development(Fischer et al.,2009;Li et al.,2017).Similarly,inhibition of FTO reduces tumori-genesis in multiple types of cancer models,while FTO is highly expressed in many cancers(Huang et al.,2020). | Sheng Zhang Zeming Wu Yue Shi Si Wang Jie Ren Zihui Yu Daoyuan Huang Kaowen Yan Yifang He Xiaoqian Liu Qianzhao Ji Beibei Liu Zunpeng Liu Jing Qu Guang-Hui Liu Weimin Ci Xiaoqun Wang Weiqi Zhang | 2022 | Protein & Cell2022，13，12： | 0 |
| 8 | Modeling and Decoupling of Coupling Tasks in Collaborative Development Process of Complicated Electronic Products显示文摘It is important to improve the development efficiency of decoupling a coupling task package according to the information relevancy relation between development tasks in the collaborative development process of complicated electronic products.In order to define the task coupling model in the development process,the weighted directed graph based on the information relevancy is established,and the correspondence between weighted directed graph model and numerical design structure matrix model of coupling tasks is introduced.The task coupling model is quantized,thereby the interactivity matrix of task package is built.A multi-goal task decoupling method based on improved genetic algorithm is proposed to decouple the task coupling model,which transforms the decoupling of task package into a multi-goal optimization issue.Then the improved genetic algorithm is used to solve the interactivity matrix of coupling tasks.Finally,the effectiveness of this decomposition method is proved by using the example of task package decoupling of collaborative development of a radar’s phased array antenna. | WANG Xiaofei LIAO Wenhe GUO Yu WANG Falin PAN Zhihao LIU Daoyuan | 2019 | Transactions of Nanjing University of Aeronautics and Astronautics2019，36，5： | 0 |
| 9 | Fabrication of Ag@Ag_(2)O-MnO_(x) composite nanowires for high-efficient room-temperature removal of formaldehyde显示文摘Efficient removal of pollutant formaldehyde(HCHO) at room temperature using transition-metal oxides remains a huge challenge to date. Manganese oxide can oxidize formaldehyde, however, how to control the valence states of manganese is the key to further improve the removal efficiency. We have successfully prepared porous manganese oxide nanowires(Mn OxNWs) with large surface area and multiple valence states of manganese using simple electrospinning followed by thermal calcination and potassium permanganate solution post-treatment(C/S process). The contents of trivalent and tetravalent manganese increased significantly after C/S process. Moreover, the composition of silver oxide coated silver nanowires(Ag@Ag_(2) O NWs) is realized by assistance with oxygen plasma, which further enhanced high valence manganese. The formaldehyde removal efficiency by Ag@Ag_(2) O–Mn Oxcomposite nanowires can reach 93.7%. The high-efficient catalytic activity is confirmed to attribute to the higher surface area of composite nanowires, the high-valence manganese and the silver oxide for oxidation of formaldehyde. | Hui Fang Chenxi Wang Daoyuan Li Shicheng Zhou Yu Du He Zhang Chunjin Hang Yanhong Tian Tadatomo Suga | 2021 | Journal of Materials Science & Technology2021，，32： | 0 |
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