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3篇 您的检索式:作者名="Yunlong Si"
    题名 作者 年代 出处 被引量
1Safety and Effectiveness of SA58 Nasal Spray Against COVID-19 Infection in Medical Personnel:An Open-Label,Blank-Controlled Study—Hohhot City,Inner Mongolia Autonomous Region,China,2022显示文摘Summary What is already known about this topic?The active ingredient of the SA58 Nasal Spray is a broad-spectrum neutralizing antibody with a high neutralizing capacity against different Omicron subvariants in vitro studies.What is added by this report?This study demonstrated the safety and effectiveness of SA58 Nasal Spray against coronavirus disease 2019(COVID-19)infection in medical personnel for the first time.What are the implications for public health practice?This study provides an effective approach for the public to reduce their risk of COVID-19 infection.The findings of this research have the potential to significantly reduce the risk of infection and limit human-to-human transmission in the event of a COVID-19 outbreak.Shujie Si Canrui Jin Jianping Li Yunlong Cao Biao Kan Feng Xue Xiaoliang Sunney Xie Liang Fang Gang Zeng Shuo Zhang Yaling Hu Xiaoping Dong 2023China CDC weekly2023,5,10:1
2Human galectin-2 interacts with carbohydrates and peptides non-classically: new insight from X-ray crystallography and hemagglutination显示文摘Yunlong Si Shiqiong Feng Jin Gao Yue Wang Zhongyu Zhang Yue Meng Yifa Zhou Guihua Tai Jiyong Su 2016Acta Biochimica et Biophysica Sinica2016,48,10:0
3Biomineralized CO gas-releasing nanoprodrug for endoplasmic reticulum stress mediated cancer therapy显示文摘The anti-tumor effect of therapeutic carbon monoxide(CO)has been considered concerning the electron transport chain on the inner mitochondrial membrane.Herein,a tumor microenvironment and photo-responsive CO nanoplatform Ca-Flav nanoparticles(NPs)were constructed through biomineralizing acryloyl-modified flavonol,which could release CO both in normoxia and hypoxia conditions upon irradiation at tumor lesion.The in vitro experiments demonstrated that the endoplasmic reticulum stress-related signal pathways could be activated through oxidative stress caused by CO mediated mitochondrial biogenesis and calcium ion turbulence induced by Ca_(3)(PO_(4))_(2)acidolysis,resulting in mitochondrial dysfunction and cell apoptosis.In addition,the Ca-Flav NPs exhibited excellent biocompatibility and tumor inhibition effect in vivo.This work provides new insight into the potential characteristics of CO,paving a new way to engineer more efficient treatment based on CO.Rui Gu Wanlan Yang Lifei Han Chao Liu Yatao Xu Yunlong Liu Weili Si Wenjun Wang Xiaochen Dong 2023Nano Research2023,16,5:0
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