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| 1 | Templated synthesis of Ti02 nanotube macrostructures and their photocatalytic properties显示文摘 | Hongbian Li Qiaoyu Zhou Yuntian Gao Xuchun Gui Long Yang Mingde Du Enzheng Shi Jidong Shi Anyuan Cao Ying Fang | 2015 | Nano Research2015，8，3： | 7 |
| 2 | Methanogenic archaea and sulfate reducing bacteria induce severe corrosion of steel pipelines after hydrostatic testing显示文摘Complex interactions within a microbial consortium can induce severe corrosion in oil pipelines.This study investigated the mechanism of microbiologically influenced corrosion(MIC)that led to failure of X52 steel pipelines after hydrostatic testing.Laboratory hydrostatic testing with untreated lake water and underground water were used to simulate and study the events that led to the actual corrosion.Biofilm analysis,weight loss,and several electrochemical measurements demonstrated rapid corrosion rates after hydrostatic testing.Analysis of microbial community structures revealed that methanogenic archaea and sulfate reducing bacteria(SRB),introduced by the hydrotest water,formed corrosive biofilms on X52 steel coupon surfaces that induced severe pitting. | Enze Zhou Jianjun Wang Masoumeh Moradi Huabing Li Dake Xu Yuntian Lou Jinheng Luo Lifeng Li Yulei Wang Zhenguo Yang Fuhui Wang Jessica A.Smith | 2020 | Journal of Materials Science & Technology2020，47，13： | 5 |
| 3 | Benthic macro red alga:A new possible bio-precursor of Jurassic mudstone source rocks in the northern Qaidam Basin,northwestern China显示文摘Whether benthic macroalga can be an important type of bio-precursor of source rocks is a contentious issue in source-rock studies,and has not been well understood.This paper represents a case study of Jurassic mudstone source rocks from the northern Qaidam Basin,northwestern China,in which the benthic macro red algae were recognized for the first time based on combined organic petrological and biomarker works.We found not only cystocarps in the algae,representative of rhodophyta,but also diahopanes,which are diagnostic biomarkers of such algae.Thus,as many reservoired oils in the northern Qaidam Basin contain abundant diahopanes,it may indicate that the red algae have contributed to hydrocarbon accumulation.This was confirmed by integrated geological and geochemical analyses.Hence,this study provides new evidence for macroalga-generated hydrocarbons. | CAO Jian BIAN LiZeng HU Kai LIU YunTian WANG LiQun YANG ShaoYong CHEN Yan PENG XiaoQun | 2009 | Science China Earth Sciences2009，52，5： | 5 |
| 4 | MicroRNA-7-5p Inhibits Migration,Invasion and Metastasis of Intrahepatic Cholangiocarcinoma by Inhibiting MyD88显示文摘Background and Aims:Intrahepatic cholangiocarcinoma(ICC)is a malignant tumor derived from intrahepatic bile duct epithelial cells.Accumulating studies report that microRNAs are widely involved in tumor migration and metastasis by regulation of target genes.miR-7-5p has been confirmed to inhibit tumor metastasis and to be related to prognosis for several malignant tumors.Our study investigated the underlying functions of miR-7-5p in ICC.Methods:The expression of miR-7-5p in ICC tissues but also in ICC cell lines was analyzed by real-time PCR.By analyzing the relationship between the clinicopathological parameters of 60 ICC patients and the expression level of miR-7-5p,the effect of miR-7-5p on the prognosis was clarified.After transfected with miR-7-5p mimics or miR-7-5p inhibitor,cell counting kit-8 assay was applied to evaluate the cells proliferation,flow cytometry was applied to analyze the cells apoptosis,wound healing assay and transwell chamber assay were applied to analyze the cell invasion and migration.A luciferase reporter assay was identified the relationship of miR-7-5p and myeloid differentiation factor 88(MyD88).Western blotting was used to analyze the proteins expression.And immunochemistry was performed to determine the expression of MYD88 in ICC tissues.Results:Our data showed the expression of miR-7-5p was down-regulated not only in ICC tissues but also in ICC cell lines compared with normal controls.Low expression of miR-7-5p was notably associated with poor prognosis in ICC patients.miR-7-5p negatively regulated cell proliferation,migration,invasion and apoptosis in ICC cells.We further verified that MyD88 was a novel target of miR-7-5p and was significantly overexpressed in ICC tissues.Overexpression of MyD88 counteracted the effects of miR-7-5p in ICC cells.Conclusions:The present findings suggest that miR-7-5p plays a pivotal role in ICC invasion by regulating MyD88.Ampliative insight into the key factors of ICC invasion may result in the development of new treatment options for ICC. | Yi Tang Zhenyong Tang Jianrong Yang Tianqi Liu Yuntian Tang | 2021 | Journal of Clinical and Translational Hepatology2021，9，6： | 3 |
| 5 | Genetic algorithm based on network anomalies in the application of intrusion detection显示文摘 | Fengbing Zhang Yuntian Yang | | 0，，： | 1 |
| 6 | Active dry yeast supplementation benefits ruminal fermentation,bacterial community,blood immunoglobulins,and growth performance in young dairy goats,but not for intermittent supplementation显示文摘This study evaluated the effects of active dry yeast(ADY)supplementation and supplementation stra-tegies on ruminal fermentation,bacterial community,blood metabolites,and growth performance in young dairy goats.Sixty young female Guanzhong dairy goats of similar age(4.00±0.50 months)and BW(19.65±0.41 kg)were randomly divided into 3 groups(n=20):(1)basal diet group(CON);(2)basal diet continuously supplemented with 3.0 g/goat per day commercial ADY(a proprietary strain of Saccharomyces cerevisiae with 5.0×10^(9)cfu/g)group(CSY);(3)basal diet with intermittently supple-mented ADY group(ISY;5 d supplementation with ADY at 4.5 g/goat per day following 5 d of no sup-plementation).The experiment lasted 67 d with the first 7 d as an adaptive period.Rumen fluid and blood samples were collected bi-weekly.Data were analyzed using the MIXED procedure combined with the SLICE option in SAS.Specific orthogonal contrasts of ADY vs.CON and CSY vs.ISY were also analyzed.During the experimental period,ADY supplementation resulted in greater DMI(P=0.03),ruminal ac-etate proportion(P<0.01)and acetylesterase activity(P=0.01),and blood contents of glucose(P=0.01)and IgM(P=0.02)and tended to have greater ADG(P=0.05)and paunch girth(P=0.06)than the CON,despite the propionate proportion(P=0.03)and contents of total protein(P=0.04)and IgA(P=0.03)being lower.The lower ruminal NH_(3)-N(P<0.01)and blood urea nitrogen(P=0.07)contents indicated greater nitrogen utilization with ADY supplementation.ADY supplementation showed persistent effects after it was stopped because the BW at 12 months of age(P=0.03)and birth weight of lambs(P=0.02)were greater than the CON.However,the ISY did not show those benefits and had significantly lower relative abundances of fiber-degrading related bacteria than the CSY.In conclusion,ADY supplementa-tion,especially continuously supplemented,may enhance ADG and ADG:DMI ratio by improving DMI,ruminal cellulolytic bacteria abundance and enzyme activity,nitrogen utilization,and immune status.These findings provide a theoretical basis for the rational application of ADY and have important practical implications for the design of nutritional strategies in growing dairy goats. | Jun Zhang Yuntian Yang Xinjian Lei Yannan Wang Yanhua Li Zhiqiang Yang Junhu Yao | 2023 | Animal Nutrition2023，，2： | 1 |
| 7 | Mechanically durable antibacterial nanocoatings based on zwitterionic copolymers containing dopamine segments显示文摘Developing an effective and durable antibacterial surface is important for surgical tools and biomedical implants.In this work,a zwitterionic copolymer containing catechol groups as biomimetic anchoring segments was coated onto 316 L stainless steel via drop-casting.Energy-dispersive X-ray spectroscopy(EDS)and water contact angle(WCA)measurements indicated that the coatings made of the copolymers containing zwitterionic and dopamine segments at the molar ratios of 8:2 and 6:4 exhibited stronger stability and mechanical durability than the one at 9:1 after inducing tape-peeling and ultrasonication damage.The mechanically durable nanocoatings exhibited excellent antibacterial performance against Staphylococcus aureus and Escherichia coli in a period of 3 days.The nanocoatings with zwitterionic and dopamine segments at the molar ratio of 8:2 were further evaluated and demonstrated durable antibacterial performance after tape-peeling and ultrasonication treatments. | Jingzhi Yang Hongchang Qian Junpeng Wang Pengfei Ju Yuntian Lou Guoliang Li Dawei Zhang | 2021 | Journal of Materials Science & Technology2021，，30： | 1 |
| 8 | Genetic algorithm based on network anomalies in the application of intrusion detection显示文摘 | Fengbing Zhang Yuntian Yang | | 0，，： | 1 |
| 9 | Protonic recognition and assembly for the creation of porous Bronsted acid catalysts with enhanced catalytic efficiency显示文摘Due to the high local concentration of substrates in confined space, porous solid Bronsted acids have been extensively explored for efficient acid-catalyzed reaction. However, the porous structures with strong Bronsted acids lack long-term stability due to chemical hydrolysis. Moreover, the products inhibition effect in confined rigid cavities severely obstructs subsequent catalysis. Here, tubular Bronsted acid catalyst with unique recognition of protons was presented by self-assembly of p H-responsive aromatic amphiphiles. The responsive assembly could mechanically transfer hydrogen ions from low-concentration acidic solution into tubular defined pores, thereby producing effective catalytic activity for Mannich reactions in mildly acidic solution. Notably, the tubular catalyst unfolded into flat sheets upon addition of triethylamine for efficient release of products, which could be recovered by subsequent acidification and the catalytic activity still remained. Therefore, the porous Bronsted acid with reversible assembly provides a new strategy for mass synthesis through increasing conversion times. | Liping Huang Mingyun Liang Yajun Fang Jehan Kim Yuntian Yang Zhegang Huang | 2023 | Chinese Chemical Letters2023，34，8： | 0 |
| 10 | Differential expression analysis of matrix metallo-proteinase 20(MMP20) in human esophageal cancer显示文摘The aim of this study was to investigate the different expressions of MMP20 in the process of esophageal cancer. RT-PCR, immunohistochemistry and Western blot were employed to detect the mRNA expression and protein expression of MMP20. Compared with the corresponding normal esophagus tissues, results showed the common trend of the dramatical overexpression of MMP20 in the esophageal cancer tissues. The analysis of MMP20 expression in different clinical early stages of esophageal cancer by RT-PCR indicated that MMP20 was much more overexpressed in the esophageal cancer with invasion than in the early stages. This suggested that MMP20 might play an important role in the progression of esophageal cancer. It probably plays a critical role in tumor invasion. | YANG Cuihong LIU Zhihua WANG Qun LUO Aiping SUN Yuntian ZHANG Xun WANG Xiuqin ZHOU Chuannong WU Min | 2001 | Chinese Science Bulletin2001，46，12： | 0 |
| 11 | HDAC4 knockdown alleviates denervation-induced muscle atrophy by inhibiting myogenin-dependent atrogene activation显示文摘Denervation can lead to progressive skeletal muscle atrophy.At present,there is no effective treatment for muscle atrophy.Histone deacetylase 4(HDAC4)has recently been found to be closely related to muscle atrophy,but the underlying mechanism of HDAC4 in denervation-induced muscle atrophy have not been described clearly.In this study,HDAC4 inhibition can effectively delay denervation-induced muscle atrophy,reduce the expression of muscle specific E3 ubiquitin ligase and autophagy related proteins,alleviate muscle fiber type transition and enhance the expression of SIRT1 and PGC1a.Transcriptome sequencing and bioinformatics analysis was performed and suggested that HDAC4 may be involved in denervation induced muscle atrophy by regulating response to denervation involved in regulation of muscle adaptation,cell division,cell cycle,apoptotic process,skeletal muscle atrophy,and cell differentiation. | Shen Yuntian Yang Xiaoming Su Wenfeng Sun Hualin | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 12 | Transient synthesis of carbon-supported high-entropy alloy sulfide nanoparticles via flash Joule heating for efficient electrocatalytic hydrogen evolution显示文摘High entropy alloys(HEA)are frequently employed as catalysts in electrocatalytic hydrogen evolution.However,the traditional high entropy alloy synthesis methods are time-consuming,energy-intensive,and environmentally polluting,which limits their application in the hydrogen evolution reaction(HER).This study leveraged the capabilities of flash Joule heating(FJH)to synthesize carbon-supported high-entropy alloy sulfide nanoparticles(CC-S-HEA)on carbon cloth(CC)with good self-standing properties within 300 ms.The carbon thermal shock generated by the Joule heating could pyrolyze the sulfur source into gas,resulting in numerous pore structures and defects on CC,forming an S-doped carbon substrate(CC-S).Then the S atoms were used to stably anchor the metal atoms on CC-S to form high-density uniformly dispersed HEA particles.The electrochemical test results demonstrated that CC-S-HEA prepared at 60 V flash voltage had HER performance comparable to Pt/C.The density functional theory(DFT)calculation indicated that the S atoms on CC-S accelerated the electron transfer between the carbon substrate and HEA particles.Moreover,the unique electronic structure of CC-S-HEA was beneficial to H*adsorption and promoted catalytic kinetics.The simplicity and versatility of FJH synthesis are of great significance for optimizing the synthesis of HEA and improving the quality of HEA products,which provides a broad application prospect for the synthesis of nanocatalysts with efficient HER performance. | Yuntian Liao Rongtao Zhu Wenjun Zhang Haiyang Zhu Yang Sun Jiale Chen Zhenhua Dong Ronghuan Lv | 2024 | Nano Research2024，17，4： | 0 |
| 13 | Chemical constituents and pharmacological effects of Lonicerae japonicae显示文摘Lonicera japonica,also known as honeysuckle,is an evergreen shrub in the family of Syzygium.By consulting Sciencedirect databases and Web of Science databases,79 related articles were found,of which 22 were related to chemical composition and pharmacological activity.These articles show that L.japonica has a wide range of pharmacological activities,including antiviral,anti-tumor,and antioxidant effects.These activities have important applications in the pharmaceutical,food,and fragrance industries.This review focuses on the chemical composition and pharmacological effects of L.japonicae,which is of great significance to the development of new drugs and therapeutic methods. | Yunpeng Yang Dan Tian Yibo Wang Yi’an Shi Yuntian Xing Yu Chen | 2024 | Asian Journal of Traditional Medicines2024，19，1： | 0 |
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