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您的检索式：作者名="Yuqiao Ding"
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| 1 | Pharmacokinetic evaluation of Shenfu Injection in beagle dogs after intravenous drip administration显示文摘Shenfu Injection(SFI) is a well-defined Chinese herbal formulation that is obtained from red ginseng and processed aconite root. The main active constituents in SFI are ginsenosides and aconitum alkaloids. In this work, ginsenosides(ginsenoside Rg1, ginsenoside Rb1 and ginsenoside Rc) and aconitum alkaloids(benzoylmesaconine and fuziline) were used as the index components to explore the pharmacokinetic behavior of SFI. A selective and sensitive HPLC–MS/MS method was developed for the quantification of ginsenosides and aconitum alkaloids in dog plasma and was used to characterize the pharmacokinetics of the five index components after intravenous drip of three different dosages of SFI in beagle dogs. The pharmacokinetic properties of the index components were linear over the dose range of2–8 m L/kg. | Yuqiao Zhang Dali Tian Yuyou Huang Ling Li Juan Mao Juan Tian Jinsong Ding | 2016 | Acta Pharmaceutica Sinica B2016，6，6： | 12 |
| 2 | Preparation of Photo-responsive DNA Supramolecular Hydrogels and Their Application as UV Radiometers显示文摘Ultraviolet light(UV)is an essential component of ambient light,but high dose UV would damage genome DNA.While semiconductors and soft materials have been employed to detect the UV,the complex process and the instrumental requirement have limited the application in daily life.In this study,taking advantage of sequence designability,a series of hydrogels with different gel-sol transition rates was constructed under the same UV intensity by introducing competing hybridization to tune the stability of the molecular network.Through estimating the transition time between each system under UV light irradiation,the intensity of UV could be roughly estimated,which provided a convenient method for the visual detection of UV. | DING Yuqiao LI Yujie YANG Bo PAN Yufan CHENG Jiafeng MENG Siwen LIU Dongsheng XU Lijin DONG Yuanchen | 2023 | Chemical Research in Chinese Universities2023，39，1： | 0 |
| 3 | Reinforcing DNA Supramolecular Hydrogel with Polymeric Multiple-Unit Linker显示文摘While supramolecular hydrogels have received growing interest due to their unique dynamic features,their relatively weak mechanical properties have largely limited their biomedical applications.In this study,we propose and demonstrate a strategy to reinforce the mechanical properties of supramolecular hydrogel by introducing polymeric multiple-unit linker(PMUL),which incorporates multiple supramolecular units into a polymeric backbone to crosslink supramolecular hydrogel.We demonstrated that PMUL can effectively improve the kinetic stability of supramolecular crosslinkers through multiple-unit interaction in a DNA supramolecular hydrogel model system,thus leading to higher mechanical strength.Meanwhile,the dynamic features of the supramolecular hydrogels have been well preserved,including shear-thinning,self-healing properties,and reversible thermal responsiveness.This strategy offers a simple but effective way for mechanical reinforcement of supramolecular hydrogels to construct novel biomaterials. | Yujie Li Yuqiao Ding Bo Yang Tianyang Cao Jiangfei Xu Yuanchen Dong Quan Chen Lijin Xu Dongsheng Liu | 2023 | CCS Chemistry2023，5，2： | 0 |
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