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| 1 | Hepatitis B virus is degraded by autophagosome-lysosome fusion mediated by Rab7 and related components显示文摘Dear Editor,With an estimated 240 million chronically infected people worldwide,hepatitis B virus(HBV)infection is a major public health problem(Schweitzer et al.,2015).Despite more than 30 years of in tense research,many aspects of the HBV life cycle still remain unknown. | Yong Lin Chunchen Wu Xueyu Wang Thekla Kemper Anthony Squire Matthias Gunzer Jiming Zhang Xinwen Chen Mengji Lu | 2019 | Protein & Cell2019，10，1： | 5 |
| 2 | 中医干预类临床证据分级系统构建思路探讨显示文摘证据分级水平是进行临床决策的重要考虑因素。中医药领域完全照搬国际常用证据评价体系存在一定局限性,故提出中医临床证据分级思路,即在遵循国际证据分级标准基础上,充分考虑中医药临床实践特点,以GRADE(Grades of Recommendation,Assessment,Development,and Evaluation)证据评价系统为基础,结合中医古籍证据及现代名医经验证据分级标准,进而整合形成中医干预类临床证据分级系统,其中古籍证据从医案来源、诊疗内容的全面性和传承性三方面进行评价,现代名医经验证据根据名医的资质、经验内容完整性、经验传承性进行评价。针对中医古籍、现代名医经验及现代研究多来源证据的整合,以定性综合为主,多来源证据的分级水平与现代研究GRADE证据评价保持一致,而中医古籍及现代名医经验作为辅助证据呈现,以期更加客观、全面地评价中医临床证据,进而指导临床实践。 | 刘少南 郭新峰 吴大嵘 ZHANG Anthony Lin XUE Charlie Changli 温泽淮 | 2023 | 中医杂志2023，64，18： | 2 |
| 3 | Complementary and alternative medicine use in Australia: a national population- based survey显示文摘 | Charlie CL Xue Anthony L Zhang Vivian Lin | 2007 | The Journal of Alternative and Complementary Medicine2007，13，6： | 1 |
| 4 | Assessment of basal heave stability for braced excavations in anisotropic clay using extreme gradient boosting and random forest regression显示文摘A finite-element analysis considering the anisotropy for the undrained shear strength was performed to examine the effects of the total stress-based anisotropic model NGI-ADP(developed by Norwegian Geotechnical Institute based on the Active-Direct simple shear-Passive concept)parameters on the base stability of deep braced excavations in clays.These parameters included the ratio of the plane strain passive shear strength to the plane strain active shear strength s_(u)^(P)=s_(u)^(A),the ratio of the unloading/reloading shear modulus to the plane strain active shear strength G_(ur)=s_(u)^(A),the plane strain active shear strength s_(u)^(A),the unit weight c,the excavation width B,the wall thickness b,and the wall penetration depth D.According to the numerical results for 1778 hypothetical cases,extreme gradient boosting(XGBoost)and random forest regression(RFR)were adopted to predict the factor of safety(FS)against basal heave for deep braced excavations.The results indicated that the anisotropic characteristics of soil parameters need to be considered when determining the FS against basal heave for braced excavation.XGBoost and RFR can yield a reasonable prediction of the FS.This paper presents a cuttingedge application of ensemble learning methods in geotechnical engineering. | Wengang Zhang Runhong Zhang Chongzhi Wu Anthony T.C.Goh Lin Wang | 2022 | Underground Space2022，7，2： | 1 |
| 5 | Effects of arginine replacement with L-citrulline on the arginine/nitric oxide metabolism in chickens:An animal model without urea cycle显示文摘Background This study examined the efficacy of L-citrulline supplementation on the arginine/nitric oxide metabolism,and intestinal functions of broilers during arginine deficiency.A total of 288 day-old Arbor Acre broilers were randomly assigned to either an arginine deficient basal diet(NC diet),NC diet+0.50%L-arginine(PC diet),or NC diet+0.50%L-citrulline(NCL diet).Production performance was recorded,and at 21 days old,chickens were euthanized for tissue collection.Results The dietary treatments did not affect the growth performance of broilers(P>0.05),although NC diet increased the plasma alanine aminotransferase,urate,and several amino acids,except arginine(P<0.05).In contrast,NCL diet elevated the arginine and ornithine concentration higher than NC diet,and it increased the plasma citrulline greater than the PC diet(P<0.05).The nitric oxide concentration in the kidney and liver tissues,along with the plasma and liver e NOS activities were promoted by NCL diet higher than PC diet(P<0.05).In the liver,the activities of arginase 1,ASS,and ASL,as well as,the gene expression of i NOS and OTC were induced by PC diet greater than NC diet(P<0.05).In the kidney,the arginase 1,ASS and ASL enzymes were also increased by PC diet significantly higher than the NC and NCL diets.Comparatively,the kidney had higher abundance of n NOS,ASS,ARG2,and OTC genes than the liver tissue(P<0.05).In addition,NCL diet upregulated(P<0.05)the m RNA expression of intestinal nutrient transporters(EAAT3 and PEPT1),tight junction proteins(Claudin 1 and Occludin),and intestinal mucosal defense(MUC2 and p Ig R).The intestinal morphology revealed that both PC and NCL diets improved(P<0.05)the ileal VH/CD ratio and the jejunal VH and VH/CD ratio compared to the NC fed broilers.Conclusion This study revealed that NCL diet supported arginine metabolism,nitric oxide synthesis,and promoted the intestinal function of broilers.Thus,L-citrulline may serve as a partial arginine replacement in broiler’s diet without detrimental impacts on the performance,arginine metabolism and gut health of chickens. | Victoria Anthony Uyanga Lijing Sun Yu Liu Meiming Zhang Jingpeng Zhao Xiaojuan Wang Hongchao Jiao Okanlawon M.Onagbesan Hai Lin | 2023 | Journal of Animal Science and Biotechnology2023，14，3： | 1 |
| 6 | 基于循证医学原则的中医干预类临床证据分级系统的构建显示文摘基于证据推荐等级的评估、制订与评价(GRADE)系统构建符合中医药临床实践特点的中医干预类临床证据分级系统。通过文献调研和核心小组讨论,中医干预类临床证据包括中医古籍、名医经验及现代临床研究证据,采用德尔菲法专家调查,确定该证据分级系统的范围、评价条目及具体的分级水平。其中,中医古籍干预类证据评价因素包括古籍医案的来源、诊疗内容完整性及古籍的传承性三方面;名医经验证据的评价因素包括名医资质、内容完整性、经验传承性三方面;评价条目采用权重赋分,将古籍及名医经验的证据均分为高、中、低3个等级。中医干预类临床证据分级水平与现代临床研究的GRADE分级一致,分为高、中、低、极低4个水平,旨在为中医临床实践和未来的研究提供参考。构建的中医干预类临床证据分级系统既遵从循证医学原则,又体现中医药临床证据特点,期望能更加全面、客观地评估支撑中医药临床实践的多来源证据。 | 刘少南 郭新峰 吴大嵘 Anthony Lin Zhang Charlie Changli Xue 温泽淮 | 2023 | 中国中西医结合杂志2023，43，8： | 1 |
| 7 | The Effect of Tai Chi on Psychosocial Well-being: A Systematic Review of Randomized Controlled Trials显示文摘 | Wei Chun Wang Anthony Lin Zhang Bodil Rasmussen Li-Wei Lin Trisha Dunning Seung Wan Kang Byung-Joo Park Sing Kai Lo | 2009 | Journal of Acupuncture and Meridian Studies2009，，3： | 1 |
| 8 | 小胶质细胞在脊髓背角突触可塑性和慢性疼痛中的重要作用显示文摘文章简介本研究发现,用强度为10 V的强直电刺激作用于小鼠的坐骨神经可引起脊髓背角C纤维突触LTP和持续至少35天的慢性疼痛,但不会引起传入神经元的损伤和炎症。为了排除强直电刺激引起的其他效应可能导致慢性疼痛,研究预先用利多卡因(钠通道阻断剂)阻断传入神经的动作电位,或阻断脊髓背角的NMDA受体。 | Li-Jun Zhou Jiyun Peng Ya-Nan Xu Wei-Jie Zeng Jun Zhang Xiao Wei Chun-Lin Mai Zhen-Jia Lin Yong Liu Madhuvika Murugan Ukpong BEyo Anthony DUmpierre Wen-Jun Xin Tao Chen Mingtao Li Hui Wang Jason RRichardson 谈智 刘先国 Long-Jun Wu | 2020 | 科学新闻2020，，2： | 0 |
| 9 | 沃尔巴克氏菌(Wolbachia)结合放射线的应用现场清除白纹伊蚊种群显示文摘《自然》杂志近期发表论文介绍中国、美国、国际原子能机构和澳大利亚科学家通过合作于2014—2017年在中国广东省广州市南沙区和番禺区2个江中沙洲岛屿,开展清除白纹伊蚊即登革病毒主要传播蚊虫的现场研究。该研究结合昆虫绝育技术(sterile insect technique,SIT),通过释放携带沃尔巴克氏菌(Wolbachia)的白纹伊蚊雄蚊,而达到靶向消灭现场野生白纹伊蚊的目的。研究结果显示,此项技术可年平均消灭现场白纹伊蚊83%~94%雌性成蚊和94%蚊卵,在部分区域实现了野生白纹伊蚊种群的灭绝。 | Xiaoying Zheng Dongjing Zhang Yongjun Li Cui Yang Yu Wu Xiao Liang Yongkang Liang Xiaoling Pan Linchao Hu Qiang Sun Xiaohua Wang Yingyang Wei Jian Zhu Wei Qian Ziqiang Yan Andrew GParker jeremie r.l.Gilles Kostas Bourtzis Jeremy Bouyer Moxun tang Bo Zheng Jianshe Yu Julian Liu Jiajia Zhuang Zhigang Hu Meichun Zhang Juntao Gong Xiaoyue Hong Zhoubing Zhang Lifeng Lin Qiyong Liu Zhiyong Hu Zhongdao Wu Luke Anthony Baton Ary AHoffmann Zhiyong Xi 毛伟(编译) 曾琴(编译) 潘晓玲(编译) 梁国栋(审校) | 2019 | 中华实验和临床病毒学杂志2019，33，5： | 0 |
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