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| 1 | Insights into the role of gut microbiota in obesity: pathogenesis, mechanisms, and therapeutic perspectives显示文摘 | Lijuan Sun Lanjing Ma Yubo Ma Faming Zhang Changhai Zhao Yongzhan Nie | 2018 | Protein & Cell2018，9，5： | 29 |
| 2 | Ultraselective carbon molecular sieve membrane for hydrogen purification显示文摘Hydrogen is a green clean fuel and chemical feedstock. Its separation and purification from hydrogencontaining mixtures is the key step in the production of hydrogen with high purity(>99.99%). In this work, carbon molecular sieve(CMS) membranes with ultrahigh permselectivity for hydrogen purification were fabricated by high-temperature(700–900 ℃) pyrolysis of polymeric precursor of phenolphthaleinbased cardo poly(arylene ether ketone)(PEK-C). The evolution of the microstructural texture and ultramicroporous structure and gas separation performance of the CMS membrane were characterized via TG-MS, FT-IR, XRD, TEM, CO2 sorption analysis and gas permeation measurements. CMS membranes prepared at 700 ℃ exhibited amorphous turbostratic carbon structures and high H2 permeability of 5260 Barrer with H2/CH4, H2/N2 and H2/CO selectivities of 311, 142, 75, respectively. When carbonized at900 ℃, the CMS membrane with ultrahigh H2/CH4 selectivity of 1859 was derived owing to the formation of the dense and ordered carbon structure. CMS membranes with ultrahigh permselectivity exhibit an attractive application prospect in hydrogen purification. | Ruisong Xu Liu He Lin Li Mengjie Hou Yongzhao Wang Bingsen Zhang Changhai Liang Tonghua Wang | 2020 | Journal of Energy Chemistry2020，29，11： | 8 |
| 3 | Diagnosis and treatment of autoimmune pancreatitis: experience with 100 patients显示文摘BACKGROUND: Autoimmune pancreatitis (AIP) is increasingly recognized as a unique subtype of pancreatitis. This study aimed to analyze the diagnosis and treatment of AIP patients from a tertiary care center in China.METHODS: One hundred patients with AIP who had been treated from January 2005 to December 2012 in our hospital were enrolled in this study. We retrospectively reviewed the data of clinical manifestations, laboratory tests, imaging examinations, pathological examinations, treatment and outcomes of the patients.RESULTS: The median age of the patients at onset was 57 years (range 23-82) with a male to female ratio of 8.1:1. The common manifestations of the patients included obstructive jaundice (49 patients, 49.0%), abdominal pain (30, 30.0%), and acute pancreatitis (11, 11.0%). Biliary involvement was one of the most extrapancreatic manifestations (64, 64.0%). Fifty-six (56.0%) and 43 (43.0%) patients were classified into focaltype and diffuse-type respectively according to the imaging examinations. The levels of serum Ig G and Ig G4 were elevated in 69.4% (43/62) and 92.0% (69/75) patients. Pathological analysis of specimens from 27 patients supported the diagnosis of lymphoplasmacytic sclerosing pancreatitis, and marked (>10 cells/HPF) Ig G4 positive cells were found in 20 (74.1%) patients.Steroid treatment and surgery as the main initial treatments were given to 41 (41.0%) and 28 (28.0%) patients, respectively. The remission rate after the initial treatment was 85.0%. Steroid was given as the treatment after relapse in most of the patients and the total remission rate at the end of follow-up was 96.0%.CONCLUSIONS: Clinical manifestations, laboratory tests, imaging and pathology examinations in combination could increase the diagnostic accuracy of AIP. Steroid treatment with an initial dose of 30 or 40 mg prednisone is effective and safe in most patients with AIP. | Lei Xin Yuan-Xiang He Xiao-Fei Zhu Qun-Hua Zhang Liang-Hao Hu Duo-Wu Zou Zhen-Dong Jin Xue-Jiao Chang Jian-Ming Zheng Changhai Hospital Second Military Medical University Chang-Jing Zuo Cheng-Wei Shao Gang Jin Zhuan Liao Zhao-Shen Li | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，6： | 6 |
| 4 | Efficient Photoelectrochemical Water Splitting by g-C_3N_4/TiO_2 Nanotube Array Heterostructures显示文摘Well-ordered TiO_2 nanotube arrays(TNTAs)decorated with graphitic carbon nitride(g-C_3N_4) were fabricated by anodic oxidization and calcination process.First, TNTAs were prepared via the anodic oxidation of Ti foil in glycerol solution containing fluorinion and 20%deionized water. Subsequently, g-C_3N_4 film was hydrothermally grown on TNTAs via the hydrogen-bonded cyanuric acid melamine supramolecular complex. The results showed that g-C_3N_4 was successfully decorated on the TNTAs and the g-C_3N_4/TNTAs served as an efficient and stable photoanode for photoelectrochemical water splitting. The facile deposition method enables the fabrication of efficient and low-cost photoanodes for renewable energy applications. | Changhai Liu Fang Wang Jin Zhang Ke Wang Yangyang Qiu Qian Liang Zhidong Chen | 2018 | Nano-Micro Letters2018，10，2： | 6 |
| 5 | Effects of Changtai granules, a traditional compound Chinese medicine, on chronic trinitrobenzene sulfonic acid-induced colitis in rats显示文摘AIM: To study the effects of Changtai granules (CTG), a traditional compound Chinese medicine, on chronic trinitrobenzene sulfonic acid-induced colitis in rats. METHODS: Healthy adult Sprague-Dawley (SD) rats of both sexes, weighing 250-300 g, were employed in the present study. The rat colitis models were induced by 2, 4,6-trinitrobenzene sulfonic acid (TNBS) enemas at a concentration of 100 mg/kg in 50% ethanol. The experimental animals were randomly divided into dexamethasone (DX) treatment, CTG treatment, and model control groups, which were intracolicly treated daily with DX (0.2 mg/kg), CTG at doses of 2.9, 5.7 and 11.4 g crude drug/kg, and the equal amount of saline respectively from 6 h following induction of the colitis in rats inflicted with TNBS to the end of study. A normal control group of rats treated without TNBS but saline enema was also included in the study. After 3 wk of treatment, the animals were assessed for colonal inflammatory and ulcerative responses with respect to mortality, frequency of diarrhea, histology and myeloperoxidase activity (MPO).RESULTS: The therapeutic effect of CTG on ulcerative colitis (UC) was better than DX. CTG effectively inhibited the activity of granulocytes, macrophages and monocytes in a dosedependent manner. Also it reduced MPO and formation of inflammation in colonic mucosal tissue. Furthermore, administration of CTG significantly prevented body mass loss and death, and decreased frequency of diarrhea in UC rats, when compared with the model control group rats.CONCLUSION: CTG would prove to be an ideal drug for chronic UC, and is warranted to be studied further. | Yong-Bing Cao,Jun-Dong Zhang,Lan Yan,De-Jun Wang,Xin-Ming Jia,Ping-Hui Gao,Ming-He Cheng,Zheng Xu,Yan Wang,Yuan-Ying Jiang,Department of Pharmacology,School of Pharmacy,Second Military Medical University,Shanghai 200433,China Ya-Ying Diao,Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China | 2005 | World Journal of Gastroenterology2005，11，23： | 5 |
| 6 | Tectonic Evolution of Southeast Central Asian Orogenic Belt: Evidence from Geochronological Data and Paleontology of the Early Paleozoic Deposits in Inner Mongolia显示文摘In this study, we present detrital zircon U-Pb dating and paleontological data for the newly identified Ayadeng Formation in the northern margin of the North China Block(NCB) and Xibiehe Formation(molasse) in the Bainaimiao arc belt(BAB), which could provide strong evidence indicating the affinity of the BAB and the evolution of the southeast Central Asian orogenic belt(CAOB). Zircon U-Pb data of siltstone samples and paleontological data indicate the Ayadeng Formation dates back to the Early Ordovician. Although its location is near the NCB, its zircon age spectra and paleontology share a closer affinity with those of Tarim and NE Gondwana, as the U-Pb data suggest an age range of 490–2 192 Ma(peak age=629, 788, 965 and 1 935 Ma), and similar gastropod fossils are found in Tarim and NE Gondwana. The U-Pb ages of meta-sandstone samples in the Xuniwusu Formation indicate a shared inheritance with the Ayadeng Formation(before 440 Ma), and the U-Pb ages of sandstone samples in the Xibiehe Formation are concentrated, with age peaks centered at ca. 420 Ma. Fossil corals occur in these two formations, and their age components also indicate a collisional setting. Therefore, it is speculated that the BAB drifted away from Tarim or NE Gondwana during the Ordovician and became attached to northern NCB between 440–420 Ma as an exotic terrane. During the Early Paleozoic, there may have occurred a collision between an arc and a continental block. | Shijie Wang Shichao Li Wenjie Li Zhongyuan Xu Jinfeng Zhang Changhai Li Qiang Shi Yang Liu Wenlong Wang Qingbin Guan | 2020 | Journal of Earth Science2020，31，4： | 4 |
| 7 | Direct reprogramming of induced neural progenitors: a new promising strategy for AD treatment显示文摘Alzheimer’s disease(AD)is a prominent form of dementia,characterized by aggregation of the amyloidβ-peptide(Aβ)plaques and neurofibrillary tangles,loss of synapses and neurons,and degeneration of cognitive functions.Currently,although a variety of medications can relieve some of the symptoms,there is no cure for AD.Recent breakthroughs in the stem cell field provide promising strategies for AD treatment.Stem cells including embryonic stem cells(ESCs),neural stem cells(NSCs),mesenchymal stem cells(MSCs),and induced pluripotent stem cells(iPSCs)are potentials for AD treatment.However,the limitation of cell sources,safety issues,and ethical issues restrict their applications in AD.Recently,the direct reprogramming of induced neural progenitor cells(iNPCs)has shed light on the treatment of AD.In this review,we will discuss the latest progress,challenges,and potential applications of direct reprogramming in AD treatment. | Siqiang Lai Min Zhang Dongsheng Xu Yiying Zhang Lisha Qiu Changhai Tian Jialin Charlie Zheng | 2015 | Translational Neurodegeneration2015，4，1： | 4 |
| 8 | Effects of 1-MCP on proline,polyamine,and nitric oxide metabolism in postharvest peach fruit under chilling stress显示文摘Peach(Prunus persica Batsch‘Yuhualu’)fruit are sensitive to chilling injury(CI).Proline,polyamine(PA),and nitric oxide(NO)are important small regulators of various metabolic pathways under chilling stress that mitigate CI.Ethylene is known to promote senescence and CI,while 1-methylcyclopropene(1-MCP)is an antagonist that inhibits the effects of ethylene.However,how1-MCP and ethylene affect proline,PA,and NO levels under chilling stress remains unclear.To address these questions,1-MCP(1μL·L^(−1))and ethylene(1μL·L^(−1))treatments were applied to peach fruit.Fruit were stored at 4°C for 28 d,then moved to 25°C for 3 d immediately after cold storage.Peach fruit exhibited CI symptoms after 7 d of cold storage with enhanced electrolyte leakage and malondialdehyde contents.The 1-MCP treatment significantly(P<0.05)restrained peach CI,and fruit did not exhibit CI symptoms until 14 d of cold storage.Proline and PAs in peach under chilling stress weremostly synthesized from glutamate and arginine,which were catalyzed by1-pyrroline-5-carboxylate synthetase and arginine decarboxylase,respectively.1-MCPtreated fruit exhibited higher proline and PA contents and enhanced chilling tolerance compared to the control,while ethylene-treated fruit had lower proline and PA contents and reduced chilling tolerance.Ethylene-treated fruit,which exhibited more severe CI symptoms compared to the control,had significantly(P<0.05)lower NO contents and NO synthase activities.However,NOmay not be a direct acting factor in 1-MCPinduced chilling tolerance,as 1-MCP-treated fruit had lower NO contents and NO synthase activities compared to the control.In conclusion,proline and PA clearly played direct and important roles in 1-MCP-induced peach chilling tolerance,while NO may not be actively involved. | Chunlu Qian Zhengjie Ji Qin Zhu Xiaohua Qi Qianqian Li Jiandong Yin Jun Liu Juan Kan Man Zhang Changhai Jin Lixia Xiao | 2021 | Horticultural Plant Journal2021，7，3： | 4 |
| 9 | Analysis of the Structure of Different Tibetan Plateau Vortex Types显示文摘Knowledge of the structure of the Tibetan Plateau vortex(TPV) is of considerable importance for understanding the generation and development mechanisms of this mesoscale system. However, our understanding of vortex structures and our ability to classify them on a physical basis is limited due to insufficient observations. The highresolution new-generation NCEP-CFSR(Climate Forecast System Reanalysis) dataset is used in the present paper to investigate the general structural features of various types of mature TPV through classification and composite structure analysis. Results indicate that the dynamic and thermodynamic structures show regional and seasonal dependency, as well as being influenced by attributes of translation, associated precipitation, and the South Asian high(SAH). The common precipitating TPV(type I), frequently occurring in the west–east-oriented zonal region between 33°and 36°N, is a notably low-level baroclinic and asymmetric system. It resides within a large-scale confluent zone and preferentially travels eastward, potentially moving out of the plateau. The heavy rain vortex(type II) corresponds to a deep vortex circulation occurring in midsummer. The low-level baroclinic sub-category(type IIa) is associated with a low-level jet and mainly originates in the area 32°–35°N, 86°–94°E, preferentially moving east of 90°E and even away from the plateau; meanwhile, the nearly upright sub-category(type IIb), which has a cold center at low levels and a warm center at mid–upper levels, is a quasi-stationary and quasi-symmetric system favorably occurring west of92°E. A western-pattern SAH exists in the upper troposphere for these two sub-categories. The springtime dry vortex in the western plateau(type III) is warm and shallow(approximately 100 h Pa deep), and zonal circulation dominates the large-scale environmental flows in the middle and upper troposphere. The precipitating vortex in the southern plateau occurring during July–August(type IV) is not affected by northerly flow at low levels. It is vertically aligned and controlled by a banded SAH. | Xinyuan FENG Changhai LIU Guangzhou FAN Jie ZHANG | 2017 | Journal of Meteorological Research2017，31，3： | 4 |
| 10 | Experimental Study on Elevated Fires in a Ceiling Vented Compartment显示文摘The impacts of elevation on fires in a ceiling vented compartment were investigated experimentally. The flame behavior of elevated fires was recorded. Various parameters including the fuel mass loss rate, the light extinction coefficient, the oxygen concentration and the gas temperature were measured. Results indicated that the variations of the flame behavior were consistent with that of the fuel mass loss rate. The fire location significantly impacted the light extinction coefficient, the oxygen concentration and the gas temperature, which all showed distinct stratification phenomena. For a higher elevated fire, the average fuel loss rate and the overall light extinction coefficient were smaller, the oxygen concentration was higher and the gas temperature was lower. In addition, the smoke descending was slower. From the perspective of those parameters the fire was less hazardous if the fire was elevated higher, which was totally different from the elevated fires in closed compartments. | Jiaqing ZHANG Shouxiang LU Qiang LI Changhai LI Man YUAN Richard YUEN | 2013 | Journal of Thermal Science2013，22，4： | 3 |
| 11 | Preliminary experimental results by the prototype of Sanya Incoherent Scatter Radar显示文摘In the past decades,the Incoherent Scatter Radar(ISR)has been demonstrated to be one of the most powerful instruments for ionosphere monitoring.The Institute of Geology and Geophysics at the Chinese Academy of Sciences was founded to build a state-ofthe-art phased-array ISR at Sanya(18.3°N,109.6°E),a low-latitude station on Hainan Island,named the Sanya ISR(SYISR).As a first step,a prototype radar system consisting of eight subarrays(SYISR-8)was built to reduce the technical risk of producing the entire large array.In this work,we have summarized the preliminary experimental results based on the SYISR-8.The amplitude and phase among 256 channels were first calibrated through an embedded internal monitoring network.The mean oscillation of the amplitude and phase after calibration were about 1 dB and 5°,respectively,which met the basic requirements.The beam directivity was confirmed by crossing screen of the International Space Station.The SYISR-8 was further used to detect the tropospheric wind profile and meteors.The derived winds were evaluated by comparison with independent radiosonde and balloon-based GPS measurements.The SYISR-8 was able to observe several typical meteor echoes,such as the meteor head echo,range-spread trail echo,and specular trail echo.These results confirmed the validity and reliability of the SYISR-8 system,thereby reducing the technical risk of producing the entire large array of the SYISR to some extent. | XinAn Yue WeiXing Wan Han Xiao LingQi Zeng ChangHai Ke BaiQi Ning Feng Ding BiQiang Zhao Lin Jin Chen Li MingYuan Li JunYi Wang HongLian Hao Ning Zhang | 2020 | Earth and Planetary Physics2020，4，6： | 3 |
| 12 | Rock roadway complementary support technology in Fengfeng mining district显示文摘This paper takes No.52 return uphill roadway of Yangquhe coal mine as a research project. Based on the research, especially its geological condition, indoor experiments, numerical simulation and theoretical analysis were employed to determine the difficult coefficients of Yangquhe project. By using these means,the difficult coefficients of the deep rock engineering were determined. From a study of the effects of crustal stress and the roof mechanism on roadway stability, the transformation mechanism in Yangquhe coal mine has been determined. As a result of this research, the interactive support technology of prestressed cable mesh was developed and the technology tested in mining engineering, which proved to be feasible. | Zeng Xiantao Jiang Yaodong Jiang Cong Ma Zhenqian Zhan Shaojian Zhang Kexue He Changhai | 2014 | International Journal of Mining Science and Technology2014，24，6： | 3 |
| 13 | Exergy Analysis of Electric Vehicle Heat Pump Air Conditioning System with Battery Thermal Management System显示文摘The exergy analysis of an electric vehicle heat pump air conditioning system(HPACS) with battery thermal management system was carried out by studying the exergy loss of each component. The results indicate that the compressor is the main source of system exergy loss in all operation conditions. The exergy loss distribution of HPACS is almost the same when the battery thermal management system integrated into the HPACS in cabin and battery mixed cooling mode and the system exergy loss was linearly related to the compressor speed in cooling modes. The performance of the HPACS is better than that of the positive temperature coefficient(PTC) heater in cabin heating mode. The degree of exergy efficiency improvement of the alternative mode was discussed at all operation conditions in cabin heating mode. The results indicate that the optimization effect using the electric vehicle HPACS to replace the PTC heater is obvious at lower compressor speed, surrounding temperature and internal condenser air flow rate. | ZHANG Kexin LI Ming YANG Changhai SHAO Zhiyuan WANG Lihong | 2020 | Journal of Thermal Science2020，29，2： | 3 |
| 14 | Creating mesopores in ZSM-48 zeolite by alkali treatment: Enhanced catalyst for hydroisomerization of hexadecane显示文摘ZSM-48 zeolites with various Si/Al ratios were hydrothermally synthesized in the H_2N(CH_2)_6NH_2(HDA)-containing media. The obtained samples were highly crystallized with minor mixed phases as evidenced by X-ray powder diffraction(XRD). The alkaline treated ZSM-48 zeolites maintained its structure under different concentrations of Na OH aqueous solution. Micropores remained unchanged while mesopores with wide pore size distribution formed after the alkaline treatment. The surface area increased from 228 to 288 m^2/g. The Br?nsted acid sites had little alteration while an obvious increase of Lewis acid sites was observed. The hydroisomerization of hexadecane was performed as the model reaction to test the effects of the alkali treatment. The conversion of hexadecane had almost no change, which was attributed to the preservation of the Br?nsted acid sites. While high selectivity to iso-hexadecane with an improved iso to normal ratio of alkanes was due to the mesopore formation and improved diffusivity. | Miao Zhang Lei Wang Yujing Chen Qiumin Zhang Changhai Liang | 2016 | Journal of Energy Chemistry2016，25，3： | 2 |
| 15 | Preparation and enhanced visible light catalytic activity of TiO 2 sensitized with Benzimidazolone Yellow H3G显示文摘 | Xili Shang Bin Li Changhai Li Xiao Wang Tianyong Zhang Shuang Jiang | 2013 | Dyes and Pigments2013，，3： | 2 |
| 16 | Surgical treatment of hepato-pancreato-biliary disease in China:the Tongji experience显示文摘Hepato-pancreato-biliary(HPB) tumors are common in China. However, these tumors are often diagnosed at intermediate/advanced stages because of the lack of a systemic surveillance program in China. This situation creates many technical challenges for surgeons and increases the incidence of postoperative complications. Therefore, Dr. Xiao-Ping Chen has made many important technical improvements, such as Chen's hepatic portal occlusion method, the anterior approach for liver resection of large HCC tumors, the modified technique of Belghiti's liver-hanging maneuver, inserting biliary-enteric anastomosis technique, and invaginated pancreaticojujunostomy with transpancreatic U-sutures. These techniques are simple, practical, and easy to learn. Owing to these advantages, complicated surgical procedures can be simplified, and the curative effects are greatly improved. These improved techniques have been widely applied in China and will benefit many additional patients. In this review, we introduce our experience of surgically treating intermediate/advanced hepatocellular carcinoma(HCC), hilar cholangiocarcinoma(HC), and pancreatic carcinoma, mainly focusing on technical innovations established by Dr. Chen in HPB surgery. | binhao zhang wei dong hongping luo xuanru zhu lin chen changhai li wei zhang shuai xiang wanguang zhang zhiyong huang xiao-ping chen | 2016 | Science China(Life Sciences)2016，59，10： | 2 |
| 17 | Soil-Transmitted Helminthiasis--China,2018显示文摘What is already known about this topic?Soil-transmitted helminthiasis(STH)is distributed widely in China and a large number of the population is afflicted.However,trends of STH infections are decreasing.What is added by this report?The most recent data indicates that the overall prevalence of STH was 1.29% in 2018 in China,which was based on the national sentinel surveillance and demonstrates a continuous decline pattern.What are the implications for public health practice?Considering the current prevalence in China and various endemic statuses in different regions,precision control measures should be implemented for the control and elimination of STH in China. | Huihui Zhu Jilei Huang Changhai Zhou Tingjun Zhu Menbao Qian Mizhen Zhang Yingdan Chen Shizhu Li | 2020 | China CDC weekly2020，2，3： | 2 |
| 18 | Complete resection of isolated pancreatic metastatic melanoma:A case report and review of the literature显示文摘Isolated metastatic melanoma of the pancreas is very rare.Currently,there is very limited experience with surgical resection of pancreatic metastasis.The potential benefit of metastasectomy can improve the quality of life and survival time of patients.We present a case of a 39-year-old Chinese male with a solitary pancreatic tumor which was considered a cystic benign lesion for years.Pathology and immunohistochemistry showed that the tumor in pancreatic tail was a metastasis from a malignant melanoma of the eyeball.No other metastastic foci were found in abdomen.The tumor was completely resected with combined distal pancreatectomy and splenectomy.The patient has survived 25 mo without any signs of local recurrence or other metastatic lesions after operation,indicating that complete surgical resection of a solitary metastatic melanoma of the pancreas can prolong the survival time of patients. | Miao-Xia He,Hui Jiang,Jian-Ming Zheng,Department of Pathology,Changhai Hospital,Second Military Medical University,Shanghai 200433,China Bin Song,Xian-Gui Hu,Yi-Jie Zhang,Department of General Surgery,Changhai Hospital,Second Military Medical University,Shanghai 200433,China | 2010 | World Journal of Gastroenterology2010，16，36： | 2 |
| 19 | 3D Geological Modeling with Multi-source Data Integration in Polymetallic Region:A Case Study of Luanchuan,Henan Province,China显示文摘The development of 3D geological models involves the integration of large amounts of geological data,as well as additional accessible proprietary lithological, structural,geochemical,geophysical,and borehole data.Luanchuan,the case study area,southwestern Henan Province,is an important molybdenum-tungsten -lead-zinc polymetallic belt in China. | Gongwen Wang~(1,2),Shouting Zhang~(1,2),Changhai Yan~3,Yaowu Song~3,Limei Wang~1 1.School of Earth Sciences and Resources,China University of Geosciences(Beijing),Beijing 100083,China. 2.State Key laboratory of Geological Processes and Mineral Resources,China University of Geosciences,Beijing 100083,China 3.Henan Institute of Geological Survey,Zhengzhou 450007,China | 2009 | 地学前缘2009，16，S1： | 1 |
| 20 | Probiotic Cocktails Alleviate Heat-induced Intestinal Barrier Dysfunction and Oxidative Stress in Broiler Chickens显示文摘[Objective]To investigate the effect of probiotic cocktails on growth performance,intestinal barrier function and antioxidant status in heat-stressed broilers.[Methods]One thousand 1-day-old broilers were randomly divided into five groups:the thermoneutral(TN),heat stress(HS),heat stress with antibiotic(HS-AB),heat stress with probiotic cocktail 1(HS-P1),and heat stress with probiotic cocktail 2(HS-P2)groups.The broilers in TN and HS groups received a diet without supplements,and those in HS-AB,HS-P1 and HS-P2 groups were fed a diet supplemented with chlortetracycline(300 g/t)or probiotic cocktail 1 or 2(100 g/t),respectively.[Results]The results showed that heat stress reduced growth performance and increased inflammatory factors,NF-κB and Toll-like receptors in jejunal mucosa coinciding with higher expression of jejunal tight junction proteins,mucin and heat stress protein mRNA.[Conclusion]Dietary probiotic cocktails had protective effects against the heat stress-induced changes in the intestine,with increased serum antioxidant capacity and growth performance of broilers.The effect of these cocktails was similar to that of chlortetracycline. | Wang Zheng Zhang Dawei Yu Wenjun Qi Changhai Yuan Jiang | 2019 | Animal Husbandry and Feed Science2019，11，3： | 1 |
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