|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Macrobenthic assemblage characteristics under stressed waters and ecological health assessment using AMBI and M-AMBI:a case study at the Xin'an River Estuary,Yantai,China显示文摘To understand the ecological status and macrobenthic assemblages of the Xin'an River Estuary and its adjacent waters, a survey was conducted for environmental variables and macrobenthic assemblage structure in September 2012(Yantai, China). Several methods are adopted in the data analysis process: dominance index,diversity indices, cluster analysis, non-metric multi-dimentional scaling ordination, AMBI and M-AMBI. The dissolved inorganic nitrogen and soluble reactive phosphorus of six out of eight sampling stations were in a good condition with low concentration. The average value of DO((2.89±0.60) mg/L) and p H(4.28±0.43) indicated that the research area faced with the risk of ocean acidification and underlying hypoxia. A total of 62 species were identified, of which the dominant species group was polychaetes. The average abundance and biomass was577.50 ind./m2 and 6.01 g/m2, respectively. Compared with historical data, the macrobenthic assemblage structure at waters around the Xin'an River Estuary was in a relatively stable status from 2009 to 2012.Contaminant indicator species Capitella capitata appeared at Sta. Y1, indicating the animals here suffered from hypoxia and acidification. AMBI and M-AMBI results showed that most sampling stations were slightly disturbed,which were coincided with the abiotic measurement on evaluating the health conditions. Macrobenthic communities suffered pressures from ocean acidification and hypoxia at the research waters, particularly those at Stas Y1, Y2 and Y5, which displays negative results in benthic health evaluation. | ZHOU Zhengquan LI Xiaojing CHEN Linlin LI Baoquan LIU Tiantian AI Binghua YANG Lufei LIU Bo CHEN Qiao | 2018 | Acta Oceanologica Sinica2018，37，5： | 4 |
| 2 | Sin- tering of limestone in calcination/carbonation cycles 显示文摘 | WANG Chunbo ZHOU Xing JIA Lufei etal | 2014 | Industrial & Engineering Chemistry Research2014，53，16： | 1 |
| 3 | Zeeman-birefringence He-Ne dual-frequency lasers based on hole-drilling birefringence in a cavity mirror 显示文摘 | ZHOU Lufei ZHANG Shulian | 2008 | Laser Physics2008，18，12： | 1 |
| 4 | Spatio-temporal variation of subtidal macrobenthic fauna and the ecological assessment of Longkou Artificial Island construction in Bohai Sea, China显示文摘To evaluate the status and changes of macrobenthic communities related to the construction of the Longkou Artificial Island(LAI)in the Bohai Sea,China,four annual surveys were conducted from 2010 to 2013.Significant changes on environmental variations and macrobenthic communities were observed in 2013 after the LAI construction a couple of years later.The changing environment was primarily presented by lower values of pH,dissolved oxygen(DO),organic material(OM)percentage,and higher salinity,suspended particulate matter(SPM)concentration and oil concentration.The main dominant species shifted from Polychaeta taxa in 2010 to Mollusca taxa in 2013 due to the changes of environmental variables.An apparent miniaturization tendency in body size of macrobenthic species was presented from 2010 to 2013.The biodiversity indices increased yearly from 2010 to 2013.However,inter-site homogenization was observed in both the community structure and health status.Multivariate AZTI Marine Biotic Index(M-AMBI)analysis showed that the health status of stations changed depending on its original status and distance to the LAI.However,no significant differences were found in the spatial distribution of either environmental variables or abundance,biomass and biodiversity of macrobenthic communities.All the results will provide a basis for the long-term ecological assessment of reclamation. | LI Xiaojing CHEN Linlin ZHOU Zhengquan LI Baoquan LIU Xin YANG Lufei LIU Bo SONG Bo | 2020 | Journal of Oceanology and Limnology2020，38，6： | 1 |
| 5 | Glioblastoma cell-derived exosomes functionalized with peptides as efficient nanocarriers for synergistic chemotherapy of glioblastoma with improved biosafety显示文摘Glioblastoma(GBM)has been regarded as one of the most deadly and challenging cancers to treat with extremely poor prognosis.The limited efficacy of current chemotherapies might be attributed to the presence of glioma stem cells(GSCs)as well as the difficulties in passing through the blood–brain barrier(BBB)and targeting tumor cells.Tumor-derived exosomes are emerging as novel and promising drug delivery systems.However,great concerns regarding the biosafety and BBB penetrability remain to be addressed.Herein,we have developed a simple and feasible strategy to engineer GBM cell-derived exosomes with improved biosafety termed“Exo@TDPs”to deliver the cargos of chemotherapeutic agents temozolomide(TMZ)and doxorubicin(DOX)into GBM tissues.Exo@TDPs decorated with angiopep-2(Ang-2)and CD133-targeted peptides improve the capacity to penetrate the BBB and target tumor cells.Both in vitro and in vivo studies demonstrate that Exo@TDPs can cross the BBB,target GBM cells,penetrate into deep tumor parenchyma,and release the therapeutic cargos effectively.Synergistic delivery of TMZ and DOX by Exo@TDPs exerts therapeutic effects to suppress the tumor growth and prolong the survival time of orthotopic syngeneic mouse GBM models.These findings suggest that our developed Exo@TDPs loaded with chemotherapeutic drugs may bring new possibilities for the application of tumor cell-derived exosomes for brain tumor treatment. | Ying Zhou Long Wang Lufei Chen Wei Wu Zhimin Yang Yuanzhuo Wang Anqi Wang Sujun Jiang Xuzhen Qin Zucheng Ye Zhiyuan Hu Zihua Wang | 2023 | Nano Research2023，16，12： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员