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| 1 | Protective actions of salvianolic acid A on hepatocyte injured by peroxidation in vitro显示文摘INTRODUCTION Salvianolic radix,one of the most commonly usedtraditional Chinese herbs,was widely studied aboutits actions against liver injury and fibrosis,and wasone of the focuses of recent research.Salvianolic acid-A(SA-A)was an aqueous solublecomponent of Salvianolic radix.In our | Hu YY Liu CH Wang RP Liu C Liu P Zhu DY | 2000 | World Journal of Gastroenterology2000，6，3： | 15 |
| 2 | Micronuclei in Nasal Mucosa, Oral Mucosa and Lymphocytes in Students Exposed to Formaldehyde Vapor in Anatomy Class显示文摘The frequency of micronuclei (MN) in cells of the nasal mucosa, oral mucosa and in lym-phocytes was evaluated for 25 students in anatomy classes exposed to formaldehyde (FA) overan 8-week period. Each student served as his or her own control. The time-weighted averageconcentration (TWA) of fOrmaldehyde in anatomical laboratories and in students’ dormitorieswas 0. 508 ± 0. 299 mg/m3 and 0. 012 ± 0. 0025mg/m3, respectively. A higher frequency ofmicronuclei was observed in nasal and oral exfoliative cells after formaldehyde exposure (3. 85± 1. 48 vs 1 .20± 0. 676 and 0. 857 ± 0. 558 vs 0. 568 ± 0. 317, paired-t test: P< 0. 001and P < 0. 01, respectively). No significant increase in the frequency of lymphocyte micronu-clei was found after formaldehyde exposure (P >0. 05 ). The present study shows that nasalmucosa cel1s exposed through respiration are the chief target of FA-induced genotoxic | YING CHEN -JlANG YAN WEN-SHENG ZHAO MEI-YING YE XIAO-LEI XIE HONG YIN SHU-YI ZHU XIAN-SHU(Department of Environmental Health, n Dgurtment of Anatomy,Tongji the ical University, Wuhan, China)(Department of Public Health, Wengzhou theical Chllege, Ch | 1997 | Biomedical and Environmental Sciences1997，10，4： | 7 |
| 3 | Capilliposide from Lysimachia capillipes inhibits AKT activation and restores gefitinib sensitivity in human non-small cell lung cancer cells with acquired gefitinib resistance显示文摘有非小的房间肺癌症(NSCLC ) 的最对待 gefitinib 的病人将最后开发抵抗。从 LC Hemsl 的 Lysimachia capillipes (LC ) capilliposide 摘录。在 vitro 并且在 vivo 反癌症效果出现。在这研究,我们调查了在有 gefitinib 的联合的 LC capilliposide 是否能克服 NSCLC 房间的抵抗到 gefitinib 并且识别包含的发信号的小径。有 LC capilliposide 的治疗独自禁止了 NSCLC 房间线(PC-9, H460, H1975, H1299 和 PC-9-GR ) 的一块面板的生长对有在 g/mL 的范围的 IC 50 价值的 gefitinib 敏感或抵抗。在 gefitinib 抵抗的 PC-9-GR 房间(它有一个 T790M EGFR 变化) , LC capilliposide (在 IC30, i.e.1.2 g/mL ) 显著地与它的 IC50 价值提高了 gefitinib 的禁止的效果从 6.80 | Shi-rong ZHANG Ya-si XU Er JIN Lu-cheng ZHU Bing XIA Xu-feng CH EN Fan-zhu LI Sheng-lin MA | 2017 | Acta Pharmacologica Sinica2017，38，1： | 7 |
| 4 | Sonochemical effect of a bifrequency irradiation显示文摘The sonochemical effect of a bifrequency orthogonal ultrasonic irradiation has been studied by using two different detecting methods. It has been shown that the sonochemical yield produced by the bifrequency irradiation appears to be much more than the sum of the yields produced separately by the two irradiations. The bifrequency irradiation, therefore, can be expected to exert a great influence on the development of sonohemical | ZHU Changping, FENG Ruo & ZHAO Yiyun Department of Physics. Jingzhou Normal College, Jingzhou 434100, China State Key Laboratory of Modern Acoustics, Nanjing University, Nanjing 210093, China Chemistry Department of Yunnan University, Kunming 650091, Ch | 2000 | Chinese Science Bulletin2000，45，2： | 7 |
| 5 | Intrahepatic transplantation of hepatic oval cells for fulminant hepatic failure in rats显示文摘AIM:To evaluate the effect of intrahepatic transplantation of hepatic oval cells(HOC)on fulminant hepatic failure(FHF)in rats.METHODS:HOC obtained from rats were labeled with green fluocescent protein(GFP)or 5,6carboxyfluorescein diacetate succinmidyl ester(CFDASE).Cell fluorescence was observed under fluorescent microscope at 6,24,48 and 72 h after labeling.CFDASE labeled HOC(5×10 6 cells each rat)were injected into livers of rats with FHF induced by D-galactosamine.Serum albumin(ALB),alanine aminotransferase(ALT),aspartate aminotransferase(AST)and total bilirubin(TBil)levels were measured at different time points.Liver function of rats was examined on days 3,7,14 and 21 after HOC transplantation.RESULTS:The positive rate of GFP and CFDA-SE labeled HOC was 10%and 90%,respectively,with no significant change in cell viabilities.The survival rate was higher in HOC transplantation group than in control group,especially 48(9/15 vs 6/15)and 72 h(9/15 vs 4/15)after HOC transplantation.The serum ALT,AST and TBil levels were decreased while the serum Alb level was increased after HOC transplantation.Fluorescence became faded and diffused in liver tissues,suggesting that proliferation and differentiation occur in transplanted HOC.CONCLUSION:CFDA-SE is superior to GFP in labeling HOC,although fluorescence intensity is decreased progressively with cell division.HOC transplantation can improve the liver function and increase the survival rate of recipients. | Chen-Xuan Wu,Qi Zou,Zheng-Yan Zhu,Ying-Tang Gao,Yi-Jun Wang,Department of Hepatobiliary,The Third Center of Affiliated Hospital of Tianjin Medical University Key Laboratory of Artificial Cells of Tianjin,Tianjin 300170,China Author contributions:Wang YJ,Wu CH and Zou Q designed the research Zou Q,Zhu ZY,Gao YT performed the research Zou Q analyzed the data Wang YJ and Wu CX wrote the paper.Supported by Tianjin Science Committee,Grant No.05SYSYJC02600 and Tianjin Health Bureau,Grant No.05KYR01 | 2009 | World Journal of Gastroenterology2009，15，12： | 7 |
| 6 | Targeting single-nucleotide polymorphisms in the 16S rRNAgene to detect and differentiate Legionella pneumophila and non-Legionella pneumophila species 显示文摘 | Zhan XY Hu CH Zhu QY | 2016 | Arch Microbiol2016，198，6： | 1 |
| 7 | Photo-induced cytotoxicity of malonic acid (C60)fullerene derivatives and its mechanism显示文摘 | Yang XL Fan CH Zhu HS | 2002 | Toxicol In Vitro2002，16，1： | 1 |
| 8 | The origin of oxidative stress in neurodegenerative disease: Mark Anthony Smith 1965-2010 显示文摘 | Zhu XW Rudy J Lee CH | 2011 | Free Radical Bio Med2011，51，2： | 1 |
| 9 | Oxidation resistant SiC coating for graphite materials显示文摘 | ZHU Q SH QIU X L MA CH W | 1999 | Carbon1999，37，： | 1 |
| 10 | PTEN induces G1 cell cycle arrest and decreases cyclin D3 levels in endometrial carcinoma cells显示文摘 | Zhu X Kwon CH Schlosshauer PW | 2001 | Cancer Res2001，61，： | 1 |
| 11 | Germline stem cells anchored by adherens junctions in the Drosophila ovary niches显示文摘 | Song X Zhu CH Doan C | 2002 | Science2002，296，5574： | 1 |
| 12 | a4b2neuronal nicotinic re- ceptor positive allosteric modulation,, an approach for impro- ving the therapeutic index of a4b2 nAChR agonists in pain 显示文摘 | Lee CH Zhu C Malysz J etal | 2011 | Bioehem Pharmacol2011，82，8： | 1 |
| 13 | An imbalance of esophageal effector and regulatory T cell subsets in experimental eosinophilic esophagitis in mice 显示文摘 | Zhu X Wang M Cramp CH | 2009 | Am J Physiol Gastroinlest Liver Physiol2009，297，3： | 1 |
| 14 | Construction of a three-dimensional pharmacophore for Bcl-2 inhibitors by flexible docking and the multiple copy simultaneous search method 显示文摘 | ZHENG CH ZHOU YJ ZHU J | 2007 | Bioorg Med Chem2007，15，19： | 1 |
| 15 | Comparison of a commercial ELISA with the modified agglutination test for detection of toxoplasma gondii antibodies in sera of naturally infected dogs and cats 显示文摘 | Zhu Ch Cui L Zhang L | 2012 | Iran J Parasitol2012，7，3： | 1 |
| 16 | SVEP and compact perturbation显示文摘 | ZHU S LI CH G | 2011 | Journal of Mathematical Analysis and Applications2011，380，： | 1 |
| 17 | Dependence of temperature coefficient of frequency (TCF) on crystallog- raphy and eigenmode in N-doped silicon contour mode micromechanical resonators显示文摘 | ZHU H SH TU CH SHAN G C | 2014 | Sensors and Actuators A : Physical2014，215，： | 1 |
| 18 | Effects of aqueous chlorine dioxide treatment on nutritional components and shelf-life of mulberry fruit显示文摘 | Chen Z Zhu CH Han ZQ | 2011 | Journal of Bioscience and Bioengineering2011，111，6： | 1 |
| 19 | Analysis of VH genes in follicular and diffuse lymphoma shows ongoing somatic mutation and multiple isotype transcripts in early diseae with changes during disease progression显示文摘 | Ottensmeier CH Thompsett AR Zhu D | 1998 | Blood1998，91，： | 1 |
| 20 | Electrical capacitance tomography measurements on vertical and inclined pneumatic conveying of granular solids显示文摘 | ZHU K RAO M WANG CH H | 2003 | Chemical Engineering Science2003，58，18： | 1 |
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