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| 1 | Spatial-temporal Evolution and Determinants of the Belt and Road Initiative: A Maximum Entropy Gravity Model Approach显示文摘The spatial interaction model is an effective way to explore the geographical disparities inherent in the Belt and Road Initiative(BRI) by simulating spatial flows. The traditional gravity model implies the hypothesis of equilibrium points without any reference to when or how to achieve it. In this paper, a dynamic gravity model was established based on the Maximum Entropy(MaxEnt) theory to estimate and monitor the interconnection intensity and dynamic characters of bilateral relations. In order to detect the determinants of interconnection intensity, a Geodetector method was applied to identify and evaluate the determinants of spatial networks in five dimensions. The empirical study clearly demonstrates a heterogeneous and non-circular spatial structure. The main driving forces of spatial-temporal evolution are foreign direct investment, tourism and railway infrastructure construction, while determinants in different sub-regions show obvious spatial differentiation. Southeast Asian countries are typically multi-island area where aviation infrastructure plays a more important role. North and Central Asian countries regard oil as a pillar industry where power and port facilities have a greater impact on the interconnection. While Western Asian countries are mostly influenced by the railway infrastructure, Eastern European countries already have relatively robust infrastructure where tariff policies provide a greater impetus. | HUANG Qinshi ZHU Xigang LIU Chunhui WU Wei LIU Fengbao ZHANG Xinyi | 2020 | Chinese Geographical Science2020,30,5: | 7 |
| 2 | Micelle or polymersome formation by PCL-PEG-PCL copolymers as drug delivery systems显示文摘Polye-caprolactone)-b-poly(ethylene glycol)-b-poly(e-caprolactone)(PCL-b-PEG-b-PCL,PCEC) triblock copolymers have been widely investigated in last several decades.Here,by altering the weight ratio of monomers in ring-opening polymerization,a series of PCEC triblock copolymers with varying hydrophobicity were synthesized,which were characterized by FTIR,1 H NMR,GPC and DSC.When PCEC copolymers with different weight ratios of PCL/PEG were dispersed in different aqueous solutions,they could self-assemble and form two distinctive nanoparticular structures:micelles or polymersomes.We then chose paclitaxel(PTX) as the model drug and encapsulate PTX into PCEC polymeric micelles and polymersomes.The physicochemical characterizations of the nanoparticles such as morphology,the size and distribution,zeta potential,drug loading content,and encapsulation efficiency were also performed.Our results showed that polymeric micelles or polymersomes from PCEC both displayed narrow size distributions and could achieve high drug loading efficiencies.In vitro cellular uptake results suggested that Nile Red loaded polymeric micelles or polymersomes displayed more internalization after 24 h incubation than those after 4 h incubation.These findings suggest that polymeric micelles and polymersomes based on PCL-b-PEG-b-PCL copolymers have great potential to effectively delivery hydrophobic drugs. | Chunyan Hu Zhuo Chen Shengjie Wu Yanfeng Han Hai Wang Hongfan Sun Deling Kong Xigang Leng Chun Wang Linhua Zhang Dunwan Zhu | 2017 | Chinese Chemical Letters2017,28,9: | 4 |
| 3 | Enhancement of transfection efficiency for HeLa cells via incorporating arginine moiety into chitosan显示文摘Arginine-rich peptides have attracted considerable attention due to their distinct internalization mechanism. It was reported that arginine and guanidino moieties were able to translocate through cell membranes and played a critical role in the process of membrane permeation. In this work, arginine was conjugated to the backbone of chitosan to form a novel chitosan derivative, arginine modified chitosan (Arg-CS). Arg-CS/DNA complexes were prepared according to the method of coacervation process. The physicochemical properties of Arg-CS and Arg-CS/DNA complexes were characterized and the transfection activity and efficiency mediated by Arg-CS/DNA complexes were investigated taking HeLa cells as target cells. Arg-CS was characterized by FTIR and 13C NMR. Arg-CS/DNA polye- lectrolyte complexes were investigated by agarose gel retardation, dynamic light scattering (DLS) and atomic force microscopy (AFM). The results revealed that the Arg-CS/DNA complexes started to form at N/P ratio of 2:1, and the size of particles varied from 100 to 180 nm. The cytotoxicity of Arg-CS and their complexes with plasmid DNA were determined by MTT assay for HeLa cells, and the results suggested that Arg-CS/DNA complexes were slightly less toxic than Arg-CS. Moreover, the derivative alone and their complexes showed significantly lower toxicity than PEI and PEI/DNA complexes, respectively. Taking HeLa cells as target cells and using pGL3-control as reporter gene, the luciferase expression mediated by Arg-CS was greatly enhanced to about 100 folds compared with the luciferase expression mediated by chitosan at different pH media. These results suggest that Arg-CS is a promising candi- date as a safe and efficient vector for gene delivery and transfection. | ZHU DunWan ZHANG HaiLing BAI JinGen LIU WenGuang LENG XiGang SONG CunXian YANG Jian LI XiaoWei JIN Xu SONG LiPing LIU LanXia LI XiuLan ZHANG Yang YAO KangDe | 2007 | Chinese Science Bulletin2007,52,23: | 4 |
| 4 | A Novel,Amorphous,Non-equiatomic FeCrAlCuNiSi High-Entropy Alloy with Exceptional Corrosion Resistance and Mechanical Properties显示文摘The exceptional corrosion resistance and mechanical properties of high-entropy metallic glasses(HE-MGs)are highly desirable for diverse critical applications.However,a long-standing problem of these alloys is that their alloy design approaches are based on limited equiatomic or near-equiatomic ratios.In this study,a novel senary alloy(non-equiatomic Fe3 Cr2 Al2 CuNi4 Si5)with amorphous structure was prepared.This alloy exhibited exceptional corrosion resistance and Vickers hardness as high as^1150 Hv at room temperature.The processing route involved amorphous powder molding via a mechanical alloying and ultrahigh pressure consolidation technique,resulting in an optimal microstructure of amorphous structure with nanoparticles uniformly distributed in the matrix alloy.This approach can effectively inhibit the crystallization of amorphous structure,thus providing a general pathway for manufacturing next-generation non-equiatomic HE-MGs with both exceptional corrosion resistance and strength. | Xigang Yang Yun Zhou Ruihua Zhu Shengqi Xi Cheng He Hongjing Wu Yuan Gao | 2020 | Acta Metallurgica Sinica(English Letters)2020,33,8: | 2 |
| 5 | Study on longitudinal wind load calculation method of cables for cable-stayed bridge显示文摘Along with the expanding of span of cable-stayed bridge,wind load becomes a more and more important controlling factor for bridge the design.A very large proportion of the wind load acting on cables has exceeded that acting on deck.There was not any detailed prescript in Chinese code for calculation of longitudinal wind load on cables due to lack of theoretical research and experiment,and conservative simplified calculation was adopted during design,which leads to conservative and uneconomical design of structures.To resolve this problem,cable force experiment was carried out during the design of Sutong Bridge.By comparing with international research results,the calculation formula of longitudinal wind drag coefficient for cables was advanced to fill the blank of bridge wind resistant code of China,and has already been adopted in the Highway Bridge Wind Resistant Design Code(JTG/T D60-01-2004)with great significance for bridge engineering. | Pei Minshan Zhang Xigang Zhu Bin Hou Bin Liu Changpeng | 2009 | Engineering Sciences2009,7,1: | 2 |
| 6 | Gentrification marion显示文摘 | Sorg Wixuan Zhu Xigang | 2010 | Internationl Journal ofurban Sciences2010,,2: | 1 |
| 7 | Poverty Decentralization or Reconcentration: An Empirical Study of the Effects of Collected Public Rental Housing in Changzhou, Jiangsu Province显示文摘Based on the supply-side reform objective, it is a great transformation of housing welfare measures in China to collect private unoccupied houses as public rental housing instead of building new ones. Through an empirical study of the Collecting Houses as Public Rental Housing Program in Changzhou, this paper finds that the collected houses is relatively scattered in the city, which is beneficial to avoiding over-centralization and marginalization of the poor families. However, it has resulted in poverty reconcentration in some old communities, probably further leading to spatial solidification of the poor as well as a further decline of old communities. Therefore it may not effectively solve the housing problems of the poor population by providing this alternative public rental housing, which is collected according to economic efficiency. Accordingly, the paper argues that it is necessary to reinforce community development and to renovate the declined communities in time, as an important supplement to housing welfare improvement. | Sun Jie Zhu Xigang Song Weixuan Liu Fengbao Li Min | 2018 | China City Planning Review2018,27,2: | 0 |
| 8 | Study on structural system of Sutong Bridge显示文摘Sutong Bridge,whose layout is [(100+100+300)+1 088 +(300+100+100)] m,marks the largest span of cable-stayed bridges in the world.The complex natural condition at the bridge site and the strict requirements for resistance of wind and seismic action make it crucial to choose a favorable structural system to assure the function and safety of the bridge.The comparison among several optional structural systems for Sutong Bridge is illustrated.After detailed analysis is carried out for viscous damper and hydraulic buffer,super liquid viscous damper with additional displacement limitation is designed for the first application in bridge engineering.The parameters for the damper is analyzed and studied and the dampers are installed successfully after quality tests. | Zhang Xigang Pei Minshan Yuan Hong Xu Liping Zhu Bin | 2009 | Engineering Sciences2009,7,1: | 0 |