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| 1 | A QoS Routing Algorithm Based on Ant Algorithm显示文摘 | S Zhang ZLiu | 2001 | IEEE ICC2001，1，5： | 1 |
| 2 | 查看详情显示文摘 | H Jiang ZLiu P Pan | | 0，，： | 1 |
| 3 | Gabor filter approach to joint fea-ture extraction and target recognition 显示文摘 | Zliu F Zhang X Hu Y | 2009 | IEEE Transac-tions on Aerospace and Electronic Systems2009，45，1： | 1 |
| 4 | Assembling colloidal Au nanoparticles with functionalized self-assembled monolayers显示文摘 | TZhu X Zhang J Wang XFu ZLiu | 1998 | Thin Solid Films1998，，： | 1 |
| 5 | Site-Specific Conjugation of Cell Wall Polyrhamnose to Protein SpyAD Envisioning a Safe Universal Group A Streptococcal Vaccine显示文摘Development of an effective vaccine against the leading human bacterial pathogen group A Streptococcus(GAS)is a public health priority.The species defining group A cell wall carbohydrate(GAC,Lancefield antigen)can be engineered to remove its immunodominant N-acetylglucosamine(GlcNAc)side chain,implicated in provoking autoimmune cross-reactivity in rheumatic heart disease,leaving its polyrhamnose core(GACPR).Here we generate a novel protein conjugate of the GACPR and test the utility of this conjugate antigen in active immunization.Instead of conjugation to a standard carrier protein,we selected SpyAD,a highly conserved GAS surface protein containing both B-cell and T-cell epitopes relevant to the bacterium that itself shows promise as a vaccine antigen.SpyAD was synthesized using the XpressTM cell-free protein expression system,incorporating a non-natural amino acid to which GACpr was conjugated by site-specific click chemistry to yield high molecular mass SpyAD-GACPR conjugates and avoid disruption of important T-cell and B-cell immunological epitopes.The conjugated SpyAD-GACPR elicited antibodies that bound the surface of multiple GAS strains of diverse M types and promoted opsonophagocytic killing by human neutrophils.Active immunization of mice with a multivalent vaccine consisting of SpyAD-GACPR,together with candidate vaccine antigens streptolysin O and C5a peptidase,protected against GAS challenge in a systemic infection model and localized skin infection model,without evidence of cross reactivity to human heart or brain tissue epitopes.This general approach may allow GAC to be safely and effectively included in future GAS subunit vaccine formulations with the goal of broad protection without autoreactivity. | Nina J.Gao Satoshi Uchiyama Lucy Pill Samira Dahesh Joshua Olson Leslie Bautista Shilpa Maroju Aym Berges Janet ZLiu Raymond HZurich Nina Mvan Sorge Jeff Fairman Neeraj Kapoor Victor Nizet | 2021 | Infectious Microbes & Diseases2021，3，2： | 0 |
| 6 | Detecting subtle yet fast skeletal muscle contractions with ultrasoft and durable graphene-based cellular materials显示文摘Human bodily movements are primarily controlled by the contractions of skeletal muscles. Unlike joint or skeletal movements that are generally performed in the large displacement range, the contractions of the skeletal muscles that underpin these movements are subtle in intensity yet high in frequency. This subtlety of movement makes it a formidable challenge to develop wearable and durable so?t materials to electrically monitor such motions with high fidelity for the purpose of, for example, muscle/neuromuscular disease diagnosis. Here we report that an intrinsically fragile ultralow-density graphene-based cellular monolith sandwiched between silicone rubbers can exhibit a highly effective stress and strain transfer mechanism at its interface with the rubber, with a remarkable improvement in stretchability(>100%). In particular, this hybrid also exhibits a highly sensitive, broadband-frequency electrical response(up to 180 Hz) for a wide range of strains. By correlating the mechanical signal of muscle movements obtained from this hybrid material with electromyography, we demonstrate that the strain sensor based on this hybrid material may provide a new, so?t and wearable mechanomyography approach for real-time monitoring of complex neuromuscular-skeletal interactions in a broad range of healthcare and human-machine interface applications. This work also provides a new architecture-enabled functional so?t material platform for wearable electronics. | Zijun He Zheng Qi Huichao Liu Kangyan Wang Leslie Roberts Jefferson ZLiu Yilun Liu Stephen JWang Mark JCook George PSimon Ling Qiu Dan Li | 2022 | National Science Review2022，9，4： | 0 |
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