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| 1 | Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism显示文摘Amycolatopsis mediterranei 被用于 rifamycin 的工业规模生产,它在 antimycobacterial 治疗起一个重要作用。作为类 Amycolatopsis 的首先定序的染色体, 236 715 底配对的包括 10 的紧张 U32 的染色体,最大的原核生物的染色体之一到目前为止曾经被定序。不同于在 streptomycetes 发现的线性拓扑学,这个染色体是圆形的,特别地类似于 Saccharopolyspora erythraea 和奴卡氏菌属 farcinica,在发展史和分类代表他们的靠近的关系。尽管在 A 预言了 9 228 编码蛋白质的基因。mediterranei 染色体 S 与那些分享了 orthologs 的最大的数字。erythraea,它被 Streptomyces coelicolor 而非 N 出人意料地跟随。farcinica,显示不同新陈代谢的特征经由改编演变到多样的生态的壁龛。除类似于那的一个核心区域以外在 streptomycetes 普通,有典型核心特征的一个新奇“伪核心”在非核心区域以内被定义,在 21 从 26 基因为第二等的代谢物生产聚类的总数被定位的地方。位于核心的 rifamycin 生合成基因簇为 rifamycin SV 的变换编码细胞色素 P450 酶必需品到 B,由比作 rifamycin 生产 B 紧张 S699 的高度相应的簇揭示了并且进一步由基因互补证实了。A 的 genomic 信息。mediterranei 表明在看起来复杂的规章的机制的控制下面不仅为各种各样的碳来源和无机的氮混合物的广泛的利用而且为新陈代谢的中介的有效 funneling 安排进第二等的抗菌素合成进程的一个新陈代谢的网络。 | Wei Zhao Yi Zhong Hua Yuan Jin Wang Huajun Zheng Ying Wang Xufeng Cen Feng Xu Jie Bai Xiaobiao Han Gang Lu Yongqiang Zhu Zhihui Shao Han Yan Chen Li Nanqiu Peng Zilong Zhang Yunyi Zhang Wei Lin Yun Fan Zhongjun Qin Yongfei Hu Baoli Zhu Shengyue Wang Xiaoming Ding Guo-Ping Zbao | 2010 | Cell Research2010，20，10： | 10 |
| 2 | Behavior of Deformation and Strength of Concrete Under Biaxial Stresses显示文摘The study of the behavior of concrete under biaxial stresses is essential to the design of offshore concrete platforms. Using the multiaxial test apparatus developed by the authors, the deformation and strength of concrete under biaxial stresses are studied experimentally. Based on the test data, an endochronic damage constitutive model and a failure criterion are proposed. According to the above model, an incremental nonlinear iterative programme is developed, and a plate sample in plane stress state is analyzed. | Song, Yupu Zbao, Guofan | 1991 | China Ocean Engineering1991，6，3： | 2 |
| 3 | A developmental view of microRNA function 显示文摘 | Zbao Y Srivastava D | 2007 | Trends Biochem Sci2007，32，4： | 1 |
| 4 | Nanoparticle syn- thesis in microreactors 显示文摘 | Zbao C X He L Z Qiao S Z | 2011 | Chemical Engineering Sclence2011，66，： | 1 |
| 5 | Stability and L2-gain analysis for switched delay systems: A delay-dependent method显示文摘 | Sun X Zbao J Hill D | 2006 | Automatica2006，42，10： | 1 |
| 6 | Aberrant cell cycle regulation in cervical carcinoma显示文摘 | Kim YT Zbao M | 2005 | Yonsei Med J2005，46，5： | 1 |
| 7 | Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control显示文摘 | Zbao B Wei X M Li W Q | 2007 | Genes Dev2007，21，21： | 1 |
| 8 | PDCD5 interacts with p53 and functions as a positive regulator in the p53 pathway 显示文摘 | Xu L Hu J Zbao Y | 2012 | Apoptosis2012，，11： | 1 |
| 9 | Multidimensional non-orthogonal Wavelet-sigmoid basis function neural network for dynamic process fault diagnosis显示文摘 | Zbao J S Cben B Z | 1998 | Computers & Chemical Engineering1998，23，1： | 1 |
| 10 | Vertically aligned car- bon nanotube arrays grown on a lamellar catalyst by fluidized bed catalytic chemical vapor deposition 显示文摘 | Zhang Q Zbao M Q Huang J Q | 2009 | Carbon2009，47，： | 1 |
| 11 | A model of stomatal conductance to quantify the relationship between leaf transpiration, microclimate and soil water stress 显示文摘 | Gao Q Zbao P Zeng X | 2002 | Plant Cell & Environment2002，25，11： | 1 |
| 12 | Generation and analysis of expressed sequence tags from a eDNA library of Moniezia expansa显示文摘 | Zbao W J Zhang H Bo X W | 2009 | Molecular & Biochemical Parasitology2009，164，1： | 1 |
| 13 | Electrochemistry Communications 显示文摘 | Ding S F Wei W Zbao G C | 2007 | 9(9): 22022007，9，9： | 1 |
| 14 | Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity 显示文摘 | Zbao Y Yang J Lao W | 2010 | Nat Cell Bio12010，12，7： | 1 |
| 15 | MiR-130b is a prognostic marker and inhibits cell proliferation and invasion in pancreat- ic cancer through targeting STAT3 显示文摘 | Zbao G Zhang JG Shi Y | 2013 | PLoS One2013，8，73： | 1 |
| 16 | Simulation of upper airway occlusion without and with mandibular advancement in obstructive sleep apnea using fluid-structure interaction 显示文摘 | Zbao M Barber T Cistulli PA | 2013 | J Biomech2013，46，15： | 1 |
| 17 | Neuroprotective properties of eatalpol on transient global cerebral ischemia in gerbils:dose-response,therapeutic time-window and long-term efficacy显示文摘 | Dan Qing Li Yong Ming Bao Jun Jun Zbao | 2004 | Brain Research2004，，1029： | 1 |
| 18 | iPS cells produce viable mice through tetraploid complementation 显示文摘 | Zbao XY Li W Lv Z | 2009 | Nature2009，461，7260： | 1 |
| 19 | Effects of EG-VEGF, VEGF and TGF-β1 on pregnancy outcome in patients un- dergoing IVF-ET treatment 显示文摘 | Gao MZ Zbao XM Lin Y | 2012 | Assist Reprod Genet2012，29，10： | 1 |
| 20 | miR-429 regulation of osmotic stress transcription factor 1 ( OSTF1 ) in tilapia during osmotic stress显示文摘 | Yah B Zbao LH Guo JT | 2012 | Biochem Biophys Res Commun2012，426，3： | 1 |
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