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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020,28,3: | 516 |
| 2 | 外刊拾贝显示文摘1.根据2018年美国糖尿病学会标准诊断中国糖尿病患病率:全国横断面研究目的:评估糖尿病患病率及其危险因素。设计:基于人群的横断面研究。背景:2015-2017年中国大陆31省份全国横断面数据。调查对象:75880名18周岁及以上代表中国大陆人口的成年人样本。主要观察指标:根据2018年美国糖尿病学会和世界卫生组织标准诊断中国成人不同性别、区域和种族的糖尿病患病率。通过问卷的方式记录调查对象的社会人口学信息、生活方式和疾病史。 | 单忠艳 Li Y Teng D Shi X Ba J 王看然 李启富 Wang K Hu J Yang J | 2020 | 国际内分泌代谢杂志2020,40,5: | 42 |
| 3 | 中国社区健康素养与高血压治疗之间的关系:回顾性队列研究显示文摘健康素养较低与临床预后差相关。健康素养与血压之间的关系研究结果不一致。该研究调查了健康素养的决定因素和健康素养与高血压管理之间的潜在关系。方法:对360例高血压患者进行回顾性队列研究。基于标准方案进行测量、体检和实验室检查。 | 刘莉 叶鹏 Shi D Li J Wang Y Wang S Liu K Shi R Zhang Q Chen X | 2017 | 中华高血压杂志2017,25,5: | 14 |
| 4 | Factors predicting survival in patients with proximal gastric carcinoma involving the esophagus显示文摘AIM:To investigate the clinicopathologic features which predict surgical overall survival in patients with proximal gastric carcinoma involving the esophagus (PGCE).METHODS:Electronic pathology database established in the Department of Pathology of the Nanjing Drum Tower Hospital was searched for consecutive resection cases of proximal gastric carcinoma over the period from May 2004 through July 2009.Each retrieved pathology report was reviewed and the cases with tumors crossing the gastroesophageal junction line were selected as PGCE.Each tumor was re-staged,following the guidelines on esophageal adenocarcinoma,according to the 7th edition of the American Joint Commission on Cancer Staging Manual.All histology slides were studied along with the pathology report for a retrospective analysis of 13 clinicopathologic features,i.e.,age,gender,Helicobacter pylori (H.pylori ) infection,surgical modality,Siewert type,tumor Bormann's type,size,differentiation,histology type,surgical margin,lymphovascular and perineural invasion,and pathologic stage in relation to survival after surgical resection.Prognostic factors for overall survival were assessed with uniand multi-variate analyses.RESULTS:Patients' mean age was 65 years (range:47-90 years).The male:female ratio was 3.3.The 1-,3and 5-year overall survival rates were 87%,61% and 32%,respectively.By univariate analysis,age,male gender,H.pylori ,tumor Bormann's type,size,histology type,surgical modality,positive surgical margin,lymphovascular invasion,and pT stage were not predictive for overall survival;in contrast,perineural invasion (P = 0.003),poor differentiation (P = 0.0003),> 15 total lymph nodes retrieved (P = 0.008),positive lymph nodes (P = 0.001),and distant metastasis (P = 0.005) predicted poor post-operative overall survival.Celiac axis nodal metastasis was associated with significantly worse overall survival (P = 0.007).By multivariate analysis,≥ 16 positive nodes (P = 0.018),lymph node ratio > 0.2 (P = 0.003),and overall pathologic stage (P = 0.002) were independent predictors for poor overall survival after resection.CONCLUSION:Patients with PGCE showed worse overall survival in elderly,high nodal burden and advanced pathologic stage.This cancer may be more accurately staged as gastric,than esophageal,cancer. | Yi-Fen Zhang Jiong Shi Hui-Ping Yu An-Ning Feng Xiang-Shan Fan Gregory Y Lauwers Hiroshi Mashimo Jason S Gold Gang Chen Qin Huang | 2012 | World Journal of Gastroenterology2012,18,27: | 12 |
| 5 | Microstructure of Laser Remelted Ni-base Alloy Coating on Stainless Steel显示文摘A 5 kW CW CO2 gas laser was used to produce NiCrBSi superalloy coatings. Powders were preplaced by plasma-spraying. The microstructure and chemical composition of the coating have been studied by SEM, XRD and HREM. The results show the coating microstructure is fine dendrites, composed of γ matrix, γ’ and boride (NiB) eutectic, the lattice parameter of the γ matrix is 0.3572 nm and there is a metallurgical bonding in interface. | Gao, Y Liang, Y Shi, CX | 1998 | Journal of Materials Science & Technology1998,14,1: | 11 |
| 6 | 胡萝卜软腐果胶杆菌巴西亚种(Pectobacterium carotovorum subsp.brasiliense)引起的黄瓜细菌性软腐病在中国发生显示文摘2014—2015年,在中国山东、山西、河北、河南、辽宁等省的黄瓜茎叶上发生了毁灭性的细菌性软腐病,造成了黄瓜产业严重的经济损失。黄瓜叶片、茎、叶柄和果实表面出现流胶;茎基部呈深褐色进而出现湿腐。受侵染的黄瓜叶边缘出现黄斑和湿腐症状,并逐渐扩散至叶片中心。从受侵染组织中分离出45个细菌菌株,在形态学特性鉴定、生理学、生物化学和16Sr RNA基因序列分析的基础上,将病原体鉴定为胡萝卜软腐果胶杆菌(Pectobacterium carotovorum)。多位点序列分析(MLSA)证实,分离菌株是胡萝卜软腐果胶杆菌巴西亚种[Pectobacterium carotovorum subsp.brasiliensis(Pcb)],病原菌归入进化枝II。重新分离获得与原始菌株相同的菌株,证实了分离菌株的致病力。寄主范围测试表明,该菌株具有广泛的寄主范围。目前为止,这是对Pcb引起的黄瓜软腐病——这一对黄瓜生产具有重要经济影响的病害在中国乃至全球范围内的首次报道。 | 冯志琴(译) meng x l chai a l shi y x xie x w ma z h li b j | 2017 | 中国植保导刊2017,37,7: | 10 |
| 7 | Anatomic structural study of cerebellopontine angle via endoscope显示文摘在颅骨底依靠寻找内视镜的技术的可能的解剖基础的背景最低限度地侵略的外科是争论的。这研究的目的是在 cerebellopontine 角度区域观察在主要的血容器和神经之间的空间关系并且为侧面、以后的颅骨底提供解剖基础经由内视镜的 retrosigmoid 锁眼 approach.Methods 的最低限度地侵略的外科这研究在三十个弄干的成年颅骨上被进行测量空间关系在之中出现以后的头部的窝的多骨的标记,并且为 retrosigmoid 锁眼 ap 定位最适当的钻区域在直径与 2.0 厘米在这个点上集中的一个洞对在 cerebellopontine 角度暴露相关结构合适。 Retrosigmoid 锁眼途径罐头减少小脑上的压力并且有效地暴露相关结构它包括面部神经, vestibulocochlear 神经,三叉的神经,舌与喉的神经,迷走神经神经,附件神经,舌下神经神经,前面的劣等的小脑的动脉,以后的劣等的小脑的动脉和迷宫的动脉,内诊镜 retrosigmoid 途径上的准确地点能避免在最低限度地侵略的外科期间拖小脑的 etc.Conclusions 。retrosigmoid 锁眼途径的申请将扩大内视镜的技术的申请。 | XIA Yin LI Xi-ping HAN De-min ZHENG Jun LONG Hai-shan SHI Jin-feng Department of Otolaryngology,Beijing Tongren Hospital,Capital Medical University Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University),Ministry of Education,Beijing 100730,China (Xia Y,Li XP,Han DM,Zheng J,Long HS and Shi JF) | 2007 | Chinese Medical Journal2007,,20: | 7 |
| 8 | Thyrotoxicosis and concomitant hypercalcemia显示文摘 | Zhang Y GaffY Zhang JQ Gao Yaing Guo XH Shi BY | 2014 | Chinese Medical Journal2014,,4: | 4 |
| 9 | Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid显示文摘 | Shi Y Hou L Tang F Jiang W Wang P Ding M Deng H | 2006 | 中国生物学文摘2006,20,7: | 4 |
| 10 | Isolation of GIF from porcine brain and studies of its zinc transfer kinetics with apo-carbonic anhydrase显示文摘 | Shi Y B Du L Zheng W J | 2002 | Biometal2002,15,4: | 2 |
| 11 | Drosophila Myc integrates multiple signaling pathways to regulate intestinal stem cell proliferation during midgut regeneration显示文摘在果蝇成年 midgut 的肠的干细胞(ISC ) 为维持织物动态平衡是必要的,并且他们的增长和区别加快以便为填满遇见需求响应损害的失去的房间。包括 JAK-STAT, EGFR 和河马(Hpo ) 小径的几个发信号小径在导致损坏的 ISC 增长被含有,但是集成这些小径的机制留下了逃犯。这里,我们证明 oncoprotein Myc (dMyc ) 的果蝇相当或相同的事物这些下游地工作表明小径调停他们 ISC 增长上的效果。在先锋房间的 dMyc 表示响应织物损坏被刺激,并且 dMyc 为加速的 ISC 增长和 midgut 新生是必要的。我们证明葡聚糖硫酸盐钠喂引起的那织物损坏经由 Hpo 小径刺激 dMyc 表示,而喂的 bleomycin 通过 JAK-STAT 和 EGFR 小径激活 dMyc。我们提供 dMyc 表示是的证据 transcriptionally 由多重发信号的小径的 upregulated,它响应织物为最佳的 ISC 增长被要求损坏。我们也获得了证据那织物损坏罐头 upregulate dMyc 表情 post-transcriptionally。最后,我们证明 dMyc 表示的基础水平在正常织物动态平衡期间为 ISC 维护,增长和系区别被要求。 | Fangfang Ren Qing Shi Yongbin Chen Alice Jiang Y Tony Ip Huaqi Jiang Jin Jiang | 2013 | Cell Research2013,23,9: | 2 |
| 12 | 纳米光子结构软膜紫外光固化纳米压印(英文)显示文摘紫外光固化纳米压印是实现纳米结构批量复制的一种新技术.其特点是低成本和高分辨,而且可以达到极高的套刻精度.为了得到大面积图案的均匀复制,可用聚二甲基硅氧烷(PDMS)制备透光的压印软模板.其母版图案可由高分辨率电子束曝光和反应离子刻蚀的方法在硅片基底上获得,然后用浇注的方法将图案转移到PDMS上.本实验特别发展了紫外光固化纳米压印适用于软膜压印的双层膜图型转移技术.该双层膜由廉价的光胶和聚甲基丙烯酸甲脂(PMMA)构成.对光胶层的压印可用普通的光学曝光仪实现.然后再将图案用反应离子刻蚀的方法转移到PMMA层中.为了证明方案的可行性,在两种不同材料的半导体基片上压印了三角晶格的光子晶体和准晶结构的图案,并用剥离的方法将它们转移到金属薄膜上,最后成功地进行了硅片刻蚀实验.相信这一纳米制做方法对大面积纳米光子结构和光学集成芯片的制造是普遍适用的. | SHI J WANG Z M BAO K PEROZ C BELOTTI M XU L P LUO C X SUN M H ZHANG B JI H OUYANG Q CHEN Y | 2006 | 纳米技术与精密工程2006,4,3: | 2 |
| 13 | Recombinant protein expression in Pichia pastoris 显示文摘 | Cregg J M Cereghino J L Shi J Y | 2000 | Mol Biotechnol2000,16,: | 2 |
| 14 | Response of antioxidative enzymes in cucumber chloroplasts to cadmium toxicity显示文摘 | Zhang F Q Shi W Y Jin Z X | 2003 | J Plant Nutr2003,26,: | 2 |
| 15 | Effect of emodin on proliferation and differentiation of 3T3-L1 preadipocyte and FAS activity 显示文摘 | Zhang C B Teng L Shi Y | 2002 | Chin Med J2002,115,7: | 2 |
| 16 | A DNA vector-based RNAi technology to suppress gene expression in mammalian cells显示文摘 | Sui G Soohoo C Affar el B Gay F Shi Y Forrester W C Shi Y | | 0,,: | 2 |
| 17 | Phycocyanin aggregation:A small angle neutron scattering and size exclusion chromatographic study显示文摘 | Shi Y Y Yun R H Van Gunsteren W F | 1988 | J Mol Biol1988,200,: | 1 |
| 18 | Evaluation of cordierite - ceria composite ceramics with oxygen storage capacity 显示文摘 | Shi Z M Liu Y Yang W Y | 2002 | Journal of the European Ceramic Society2002,22,: | 1 |
| 19 | Side-stream eigarette smoke unduces dose-response in systemic inflammatory, cytokine production and oxidative stress 显示文摘 | Zhang J Liu Y Shi J | 2002 | Exp Biol Med2002,227,9: | 1 |
| 20 | Embedding image watermarks in DC components显示文摘 | Huang J W Shi Y Q Shi Y | 2000 | IEEE Transactions on Circuits and Systems for Video Technology2000,10,6: | 1 |