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| 1 | Capecitabine treatment patterns in patients with gastroesophageal cancer in the United States显示文摘AIM:To assess the use of capecitabine-based therapy and associated complication rates in patients with gastroesophageal cancer(GEC)in a real-world treatment setting. METHODS:Patients with claims between 2004 and 2005 were identified from the Thomson Reuters MarketScan databases.Capecitabine regimens were compared with 5-fluorouracil(5-FU)and other chemotherapy regimens,and were stratified by treatment setting. RESULTS:We identified 1013 patients with GEC:approximately half had treatment initiated with a 5-FU regimen,whereas 11%had therapy initiated with a capecitabine regimen.The mean capecitabine dose overall was 2382±1118 mg/d,and capecitabine was used as monotherapy more often than in combination. Overall,5-FU regimens were the most common treatment option in neoadjuvant and adjuvant settings, while other non-capecitabine regimens were used more widely in first-and second-line settings.The overall unadjusted complication rate for capecitabine regimens was about half of that seen with 5-FU regimens.In multivariate analyses,capecitabine recipients had a 51%(95%CI:26%-81%)lower risk of developing any complication than 5-FU recipients did.The risk of developing bone marrow,constitutional,gastrointestinal tract,infectious,or skin complications was lowerwith capecitabine therapy than with 5-FU.CONCLUSION:Capecitabine appeared to have a favorable side effect profile compared with 5-FU,which indicates that it may be a treatment option for GEC. | Muhammad Wasif Saif Nianwen Shi Susan Zelt | 2009 | World Journal of Gastroenterology2009，15，35： | 3 |
| 2 | The risk of rupture in untreated aneurysms: The impact of size, gender, and expansion rate显示文摘 | Peter M. Brown David T. Zelt Boris Sobolev | 2003 | Journal of Vascular Surgery2003，，2： | 2 |
| 3 | Three-Dimensional Seismic Re- fraction Tomography: A Comparison of Two Methods Applied to Data from the Faeroe Basin显示文摘 | Zelt C A Barton P J | 1998 | Geophys Res1998，103，： | 1 |
| 4 | The run-up of nonbreaking and breaking solitary waves显示文摘 | ZELT J A | 1991 | Coastal Engineering1991，15，3： | 1 |
| 5 | Lithospheric structure of the southern Canadian Cordillera from a network of seismic refraction lines显示文摘 | CLOWES R M ZELT C A AMOR J R | 1995 | Can J Earth Sciences1995，32，： | 1 |
| 6 | 3 D finite-difference reflection trav- eltimes显示文摘 | Hole J B Zelt | 1995 | Geophysical Journal International1995，121，5： | 1 |
| 7 | Seismic characterization of a gas hydrate system in the Gulf of Mexico using wide-aperture data显示文摘 | Jaiswal Priyank Zelt | 2006 | Geophysical Journal International2006，165，1： | 1 |
| 8 | Seismic traveltime inversion for 2-D crustal velocity structure 显示文摘 | Zelt C A Smith R B | 1992 | Geophysical Journal Interna- tional1992，108，1： | 1 |
| 9 | A Lagrangian model for water induced harbor oscillations显示文摘 | ZELT J A RAICHLEN F | 1990 | Journal of Fluid Mechanics1990，213，： | 1 |
| 10 | Seismic traveltime inversion for 2-D crustal velocity structure显示文摘 | ZELT C A SMITH R B | 1992 | Geophys J Int1992，108，： | 1 |
| 11 | 3-D finite-difference reflection travel times显示文摘 | Zelt B C | 1995 | Geophys J Int1995，121，： | 1 |
| 12 | The run-up of non-breaking and breaking solitary waves 显示文摘 | ZELT J A | 1991 | Coastal Engineering1991，15，3： | 1 |
| 13 | Seismic traveltime inversion for 2-D crustal velocity structure显示文摘 | Zelt C A Smith R B | 1992 | Geophys1992，108，： | 1 |
| 14 | The runup of nonbreaking and breaking solitary waves显示文摘 | ZELT J A | 1991 | Coastal Engineering1991，15，： | 1 |
| 15 | Three--dimensional seismic refraction tomography: a comparison of two methods applied to data from the FaeroeBasin显示文摘 | Zelt C A Barton P J | 1998 | J Geophys Res1998，103，： | 1 |
| 16 | Inversion of three- dimentional wide--angle seismic data from the southwestern Canadia Cordillera显示文摘 | Zelt B C Ellis R M Clowes R M | 1996 | J Geophys Res1996，286，209： | 1 |
| 17 | 3D simultaneous seismic refraction and reflection tomography of wide--angle data from the central Chilean margin显示文摘 | Zelt C A Hojka A M Flueh E R | 1999 | J Geophys Res Lett1999，26，： | 1 |
| 18 | 3--D velocity structure from simultaneous traveltime inversion of in--line seismic data along intersecting profiles显示文摘 | Zelt C A | 1994 | J Geophys Int1994，118，795： | 1 |
| 19 | Seismic traveltime inversion for 2--D crustal velocity structure显示文摘 | Zelt C A Smith R B | 1994 | J C eophys Int1994，108，16： | 1 |
| 20 | Seismic traveltime inversion for 2-D crustal velocity structure显示文摘 | Zelt C A Smith R B | 1992 | Geophys J Int1992，108，： | 1 |
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