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33篇 您的检索式:作者名="Zhang Hualei"
    题名 作者 年代 出处 被引量
1Floor stress evolution laws and its effect on stability of floor roadway显示文摘According to the distribution of abutment stress in a stope,this research established the mechanical model of mining abutment pressure transmission in floor base on the theory of semi-infnite plate body in elasticity.This study takes the 762 working face of Haizi Coal Mine as a case in point,and analyzed the dynamic evolution law of seam floor stress during the mining process.With an organic combination of the mining floor stress and surrounding rock stress,the study obtained the change laws of the maximum principle stress and the minimum one for the floor roadway surrounding rock when mining the upper working face.Considering the non-constant pressure force state and the cracks revolution mechanisms of floor roadway surrounding rock,the research built the mechanical model of roadway stress.Simulation results verify the reliability of the above conclusions.Moreover,this model could provide the theoretical basis and technical support for controlling floor roadway surrounding rock.Zhang Hualei Cao Jianjun Tu Min 2013International Journal of Mining Science and Technology2013,23,5:20
2Influence of the post-treatment of HZSM-5 zeolite on catalytic performance for alkylation of benzene with methanol显示文摘The porous material HZSM-5 zeolite with micro-mesopore hierarchical porosity was prepared by post-treatment(combined alkali treatment and acid leaching) of parent zeolite and its catalytic performance for benzene alkylation with methanol was investigated. The effect of post-treatment on the textural properties was characterized by various techniques(including ICP-AES, XRD, nitrogen sorption isotherms, SEM, NH3-TPD, Py-IR and TG). The results indicated that the post-treatment could modify the structural and acidic properties of HZSM-5 zeolite. In this procedure, not only additional mesopores were created by selective extraction of silicon but also the acidity was tuned. Consequently, the modified HZSM-5 zeolite showed larger external surface area with less acid sites as compared to the parent zeolite. It was found out that the modified zeolite exhibited a higher benzene conversion and xylene selectivity for alkylation of benzene with methanol as well as excellent life span of the catalyst than conventional ones. This can be explained by the facts that the presence of additional mesopores improved the diffusion property in the reactions. Furthermore, the modified zeolite showed an appropriate Br?nsted acidity for effective suppression of the side reaction of methanol to olefins, thus reduced the accumulation of coke on the HZSM-5 zeolite, which was favorable for the catalyst stability. In comparison with the parent HZSM-5 zeolite,the modified zeolite by alkali treatment and acid leaching showed better performance for the benzene alkylation with methanol.Qingtao Wang Wenwen Han Hualei Hu Jinghui Lyu Xiaolong Xu Qunfeng Zhang Hongjing Wang Xiaonian Li 2017Chinese Journal of Chemical Engineering2017,25,12:13
3Benzene alkylation with methanol over phosphate modified hierarchical porous ZSM-5 with tailored acidity显示文摘The acidity and acid distribution of hierarchical porous ZSM-5 were tailored via phosphate modification. The catalytic results showed that both benzene conversion and selectivity of toluene and xylene increased with the presence of appropriate amount of phosphorus. Meanwhile, side reactions such as methanol to olefins related with the formation of by-product ethylbenzene formation and isomerization of xylene to meta-xylene were suppressed efficiently. The acid strength and sites amount of Br?nsted acid of the catalyst were crucial for improving benzene conversion and yield of xylene, whereas passivation of external surface acid sites played an important role in breaking thermodynamic equilibrium distribution of xylene isomers.Jinghui Lyu Hualei Hu Carolyn Tait Jiayao Rui Caiyi Lou Qingtao Wang Wenwen Han Qunfeng Zhang Zhiyan Pan Xiaonian Li 2017Chinese Journal of Chemical Engineering2017,25,9:11
4Convolutional neural networks for expert recommendation in community question answering显示文摘Community Question Answering(CQA) is becoming an increasingly important web service for people to search for expertise and to share their own. With lots of questions being solved, CQA have built a massive, freely accessible knowledge repository, which can provide valuable information for the broader society rather than just satisfy the question askers. It is critically important for CQA services to get high quality answers in order to maximize the benefit of this process. However, people are considered as experts only in their own specialized areas. This paper is concerned with the problem of expert recommendation for a newly posed question, which will reduce the questioner's waiting time and improve the quality of the answer, so as to improve the satisfaction of the whole community. We propose an approach based on convolutional neural networks(CNN) to resolve this issue. Experimental analysis over a large real-world dataset from Stack Overflow demonstrates that our approach achieves a significant improvement over several baseline methods.Jian WANG Jiqing SUN Hongfei LIN Hualei DONG Shaowu ZHANG 2017Science China(Information Sciences)2017,60,11:11
5Numerical simulation study on the influence of the ground stress field on the stability of roadways显示文摘We adopt the concept of generalized plane strain to model a roadway in a stress field.This can avoid limitations caused by simplifying the stress analysis as plane strain.FLAC3D was used to investigate the maximum tensile stress and displacement of a roadway in a known stress field for angles,α,between the roadway axial direction and the maximum principal stress of 0°,30°,45°,60° and 90°.This theory was applied to the analysis of an engineering case.The results indicate that stress and displacement of the surrounding rock increase as the angle,α,increases.This provides some significant guidance for a reasonable layout of roadways in a known stress field.ZHANG Hualei 2010Mining Science and Technology2010,20,5:7
6Synthesized high-silica hierarchical porous ZSM-5 and optimization of its reaction conditions in benzene alkylation with methanol显示文摘In our present work, the high-silica hierarchical porous ZSM-5 with appropriate Br(o|¨)nsted acidity and hierarchical porous structure was synthesized by sol-gel method for continuously catalytic conversion of benzene alkylation with methanol to xylene. The effects of temperature, pressure, benzene/methanol molar ratio and weight hour space velocity(WHSV) on the catalytic performance of the catalyst were investigated as well. As a result, the high-silica hierarchical porous ZSM-5 showed great performance as the yield of xylene was up to 41.1% under the optimum reaction conditions(500 ℃,0.1 MPa,M_(benzene)/M_(methanol)= 1:1.5 and WHSV=4 h 1), while the selectivity to by-product, ethylbenzene, was well suppressed(below 0.1%). In addition, the catalyst structure and properties were characterized by the means of XRD, IR, TPD,SEM, TEM and N_2 physical adsorption technologies.Jiayao Rui Jinghui Lyu Hualei Hu Qunfeng Zhang Qingtao Wang Xiaonian Li 2019Chinese Chemical Letters2019,30,3:5
7Breaking mechanism and control technology of sandstone straight roof in thin bedrock stope显示文摘The key problem to be solved urgently is how to avoid the occurrence of support break-off and water inrush in the stoping of sandstone straight roof under the action of load transfer in unconsolidated aquifer.For this reason,taking the thin bedrock 1602(3)working face of Huainan(the middle part of Anhui Province)Panyi Coal Mine as the engineering background,this study establishes the stope mining model by using the discrete element UDEC software and the mathematics mechanical model of the support load,and analyzes the reason of support crushing and decides to re-mining the working face by using the compulsive roof caving method.It is concluded that when the working face of sandstone straight roof is broken,the'voussoir beam'structure cannot be formed and acts on the support in the form of cantilever beam,but only when it falls to the high key stratum can the'voussoir beam'structure be formed and at this point,at this time,the bracket bears the weight of the rock layer in the range from the fractured sandstone layer to the lower critical layer.The working resistance of the support increases with the increase of the thickness and the breaking length of straight sandstone roof.When the breaking length of the roof reaches a certain extreme value,the support crushing accidents will occur.Managing roof with compulsive roof caving method can reduce the intensity of rock pressure in the stope,and the working face can be safely stoped,which provides a certain reference for similar conditions.Hualei Zhang Min Tu Hua Cheng Yongzhi Tang 2020International Journal of Mining Science and Technology2020,30,2:4
8Conductive Biomaterials as Bioactive Wound Dressing for Wound Healing and Skin Tissue Engineering显示文摘Conductive biomaterials based on conductive polymers,carbon nanomaterials,or conductive inorganic nanomaterials demonstrate great potential in wound healing and skin tissue engineering,owing to the similar conductivity to human skin,good antioxidant and antibacterial activities,electrically controlled drug delivery,and photothermal effect.However,a review highlights the design and application of conductive biomaterials for wound healing and skin tissue engineering is lacking.In this review,the design and fabrication methods of conductive biomaterials with various structural forms including film,nanofiber,membrane,hydrogel,sponge,foam,and acellular dermal matrix for applications in wound healing and skin tissue engineering and the corresponding mechanism in promoting the healing process were summarized.The approaches that conductive biomaterials realize their great value in healing wounds via three main strategies(electrotherapy,wound dressing,and wound assessment)were reviewed.The application of conductive biomaterials as wound dressing when facing different wounds including acute wound and chronic wound(infected wound and diabetic wound)and for wound monitoring is discussed in detail.The challenges and perspectives in designing and developing multifunctional conductive biomaterials are proposed as well.Rui Yu Hualei Zhang Baolin Guo 2022Nano-Micro Letters2022,14,1:4
9Emerging hemostatic materials for non-compressible hemorrhage control显示文摘Non-compressible hemorrhage control is a big challenge in both civilian life and the battlefield,causing a majority of deaths among all traumatic injury mortalities.Unexpected non-compressible bleeding not only happens in pre-hospital situations but also leads to a high risk of death during surgical processes throughout in-hospital treatment.Hemostatic materials for pre-hospital treatment or surgical procedures for non-compressible hemorrhage control have drawn more and more attention in recent years and several commercialized products have been developed.However,these products have all shown non-negligible limitations and researchers are focusing on developing more effective hemostatic materials for non-compressible hemorrhage control.Different hemostatic strategies(physical,chemical and biological)have been proposed and different forms(sponges/foams,sealants/adhesives,microparticles/powders and platelet mimics)of hemostatic materials have been developed based on these strategies.A summary of the requirements,state-of-the-art studies and commercial products of non-compressible hemorrhage-control materials is provided in this review with particular attention on the advantages and limitations of their emerging forms,to give a clear understanding of the progress that has been made in this area and the promising directions for future generations.Ruonan Dong Hualei Zhang Baolin Guo 2022National Science Review2022,9,11:3
10Antibacterial biomaterials for skin wound dressing显示文摘Bacterial infection and the ever-increasing bacterial resistance have imposed severe threat to human health.And bacterial contamination could significantly menace the wound healing process.Considering the sophisticated wound healing process,novel strategies for skin tissue engineering are focused on the integration of bioactive ingredients,antibacterial agents included,into biomaterials with different morphologies to improve cell behaviors and promote wound healing.However,a comprehensive review on antibacterial wound dressing to enhance wound healing has not been reported.In this review,various antibacterial biomaterials as wound dressings will be discussed.Different kinds of antibacterial agents,including antibiotics,nanoparticles(metal and metallic oxides,lightinduced antibacterial agents),cationic organic agents,and others,and their recent advances are summarized.Biomaterial selection and fabrication of biomaterials with different structures and forms,including films,hydrogel,electrospun nanofibers,sponge,foam and three-dimension(3D)printed scaffold for skin regeneration,are elaborated discussed.Current challenges and the future perspectives are presented in thismultidisciplinary field.We envision that this review will provide a general insight to the elegant design and further refinement of wound dressing.Yuqing Liang Yongping Liang Hualei Zhang Baolin Guo 2022Asian Journal of Pharmaceutical Sciences2022,17,3:3
11Regulation of innate immune responses by rabies virus显示文摘Rabies virus(RABV)is an infectious and neurotropic pathogen that causes rabies and infects humans and almost all warm-blooded animals,posing a great threat to people and public safety.It is well known that innate immunity is the critical first line of host defense against viral infection.It monitors the invading pathogens by recognizing the pathogen-associated molecular patterns and danger-associated molecular patterns through pattern-recognition receptors,leading to the production of type I interferons(IFNα/β),inflammatory cytokines,and chemokines,or the activation of autophagy or apoptosis to inhibit virus replication.In the case of RABV,the innate immune response is usually triggered when the skin or muscle is bitten or scratched.However,RABV has evolved many ways to escape or even hijack innate immune response to complete its own replication and eventually invades the central nervous system(CNS).Once RABV reaches the CNS,it cannot be wiped out by the immune system or any drugs.Therefore,a better understanding of the interplay between RABV and innate immu-nity is necessary to develop effective strategies to combat its infection.Here,we review the innate immune responses induced by RABV and illustrate the antagonism mechanisms of RABV to provide new insights for the control of rabies.Haili Zhang Jingbo Huang Yumeng Song Xingqi Liu Meichen Qian Pei Huang Yuanyuan Li Ling Zhao Hualei Wang 2022Animal Models and Experimental Medicine2022,5,5:2
12Identification of Oblate Band in Odd-odd ^(184)Au显示文摘The high-spin states in 184Au were populated by using the 159Tb( 29Si, 4ng) 184Au reaction at a bombarding energy of 140 MeV. The 29Si beam of 8 pnA was provided by the accelerator complex of the Tandem-XTU and ALPI at the Laroratori Nazionale di Legnero, Italy, and focussed onto a natural metallic 159Tb foilZhang Yuhu Wang Hualei G. de Angelis N. Maiginean A. Gadea D. R. Napoli M. Axiotis C. R.usu T. Martinez Zhou Xiaohong Fang Yongde Guo Wentao Liu Minliang Lei Xiangguo Guo Yingxiang 2004近代物理研究所和兰州重离子加速器实验室年报:英文版2004,,1:2
13Evidence for charge and spin density waves in single crystals of La_(3)Ni_(2)O_(7) and La_(3)Ni_(2)O_(6)显示文摘Charge and spin orders are intimately related to superconductivity in copper oxide superconductors.Elucidation of the competing orders in various nickel oxide compounds is crucial,given the fact that superconductivity has been discovered in Nd_(0.8)Sr_(0.2)NiO_(2)films.Herein,we report structural,electronic transport,magnetic,and thermodynamic characterizations of single crystals of La_(3)Ni_(2)O_(7)and La_(3)Ni_(2)O_(6).La_(3)Ni_(2)O_(7)is metallic with mixed Ni^(2+)and Ni^(3+)valent states.Resistivity measurements yield two transition-like kinks at~110 and 153 K.The kink at 153 K is further revealed from magnetization and specific heat measurements,indicative of the formation of charge and spin density waves.La_(3)Ni_(2)O_(6)single crystals obtained from the topochemical reduction of La_(3)Ni_(2)O_(7)are insulating and show an anomaly at~176 K on magnetic susceptibility.The transition-like behaviors of La_(3)Ni_(2)O_(7)and La_(3)Ni_(2)O_(6)are analogous to those observed in La_(4)Ni_(3)O_(10) and La_(4)Ni_(3)O_(8),suggesting that charge and spin density waves are a common feature in the ternary La-Ni-O system with mixed-valent states of nickel.Zengjia Liu Hualei Sun Mengwu Huo Xiaoyan Ma Yi Ji Enkui Yi Lisi Li Hui Liu Jia Yu Ziyou Zhang Zhiqiang Chen Feixiang Liang Hongliang Dong Hanjie Guo Dingyong Zhong Bing Shen Shiliang Li Meng Wang 2023Science China(Physics,Mechanics & Astronomy)2023,66,1:2
14Association of Sandstone-Type Uranium Mineralization in the Northern China with Tectonic Movements and Hydrocarbons显示文摘In the continental basins of Northern China(NC),a series of energy resources commonly co-exist in the same basin.As the three typical superimposed basins of different genesis in the NC,the Junggar,Ordos,and Songliao basins were chosen as the research objects.The favorable uraniumbearing structures are generally shown as a basin-margin slope or transition belt of uplifts with the development of faults,which are conducive to a fluid circulation system.The Hercynian,Indosinian,and Yanshanian movements resulted in the development of uranium-rich intrusions which acted as the significant uranium sources.The main hydrocarbon source rocks are developed in the Carboniferous,Permian,Jurassic and Cretaceous.The mature stage of source rocks is concentrated in the Jurassic–Cretaceous,followed by the multi-stage expulsion events.Influenced by the India-Eurasian collision and the subduction of the Pacific Plate,the tectonic transformation in the Late Yanshanian and Himalayan periods significantly influenced the sandstone-type uranium mineralization.The hydrocarbon reservoirs are spatially consistent with sandstone-type uranium deposits,while the hydrocarbon expulsion events occur in sequence with sandstone-type uranium mineralization.In the periphery of the faults or the uplifts,both fluids met and formed uranium concentration.The regional tectonic movements motivate the migration of hydrocarbon fluids and uranium mineralization,especially the Himalayan movement.Yin Chen Peisen Miao Jianguo Li Ruoshi Jin Hualei Zhao Lulu Chen CongWang HaoyuYu Xiaoru Zhang 2022Journal of Earth Science2022,33,2:2
15Genetically engineered bacterial-like particles induced specific cellular and humoral immunity as effective tick-borne encephalitis virus vaccine显示文摘Tick-borne encephalitis(TBE)is a natural focal disease with fatal encephalitis induced by tick-borne encephalitis virus(TBEV),seriously threatening human and public health.Protection of TBE depends on vaccination with inactivated vaccine,which requires high cost and multiple immunizations.Here,we construct genetically engineered bacterial-like particles(BLPs)as an effective TBEV vaccine with simplified immunizations and improved immune efficacy.The TBEV BLPs involve the combination of the gram-positive enhancer matrix from Lactococcus lactis,and TBEV envelope(E)protein expressed by genetically engineered recombinant baculovirus.The prepared TBEV BLPs can effectively stimulate the activation of dendritic cells to present the TBEV E proteins to T and B cells,leading to strong and durable cellular and humoral immune responses in mice.Surprisingly,the serum levels of specific IgG antibodies in mice remain about 10^(6)at 6 months after the secondary immunization.Overall,the TBEV BLPs can be used as a potent vaccine candidate,laying the foundation for developing novel TBEV genetically engineered vaccines.Mengyao Zhang Hongli Jin Yuanyuan Li Cuicui Jiao Pei Huang Yujie Bai Zhiyuan Gong Haili Zhang Shunjie Liu Hualei Wang 2023Aggregate2023,4,3:1
16Rabies virus glycoprotein is an important determinant for the induction of innate immune responses and the pathogenic mechanisms显示文摘Zhang Hualei Wang Fazal Mahmooda 2013162 (2-4):601-6132013,162,24:1
17Structural and Functional Design of Electrospun Nanofibers for Hemostasis and Wound Healing显示文摘Electrospun nanofibers have been extensively studied in the biomedical field,including the controlled release of drugs,bionics,cell scaffolds,hemostasis,wound healing,and tissue engineering because of their high porosity,large surface area-to-volume ratio,and programmable features.In recent years researchers have continuously broadened the structural design of electrospun nanofibers,which have evolved from one-dimensional to three-dimensional structures,in order to diversify their function.These properties enable nanofibers to structurally and functionally mimic natural extracellular matrix(ECM),thereby obtaining a favorable physiological microenvironment for both wound healing and hemostasis due to improved blood coagulation and concentration.A comprehensive review summarizing the recent research progress of the structural and functional design of electrospun nanofibers for hemostasis and wound healing,on the other hand,is lacking.This review summarizes electrospun nanofibers used for hemostasis and wound healing,with a focus on structural design and modification strategies.The wide application of electrospun nanofibers in hemostasis and wound healing is clarified using a special structural and innovative design for electrospinning.The advantages and limitations of electrospun nanofibers with various structural forms are also discussed,as are the main challenges and future development directions for the development of structurally specific electrospun nanofibers for hemostasis and wound healing.Yutong Yang Yuzhang Du Jie Zhang Hualei Zhang Baolin Guo 2022Advanced Fiber Materials2022,4,5:1
18High suppressionof the formation of ethylbenzene in benzene alkylationwith methanol over ZSM-5 catalyst modified byplatinum显示文摘Hu Hualei Zhang Qunfeng Cen Jie 2014Catalysis Communications2014,57,:1
19High suppression of the formation of ethylbenzene in benzene alkylation with methanol over ZSM-5 catalyst modified by platinum显示文摘Hu Hualei Zhang Qunfeng Cen Jie 2014Catal Commun2014,57,:1
20Incorporation of Escherichia coli heat-labile enterotoxin B subunit into rabies virus particles enhances its immunogenicity in mice and dogs显示文摘Although inactivated vaccines against rabies have the advantage of high safety,effective protection against rabies virus(RABV)infection often requires multiple,high-dose immunization.Incorporating a molecular adjuvant into the viral particles has been found to be a useful strategy to promote the immune effectiveness of inactivated vaccines.In this study,we constructed a recombinant virus,rCVS11-LTB,which chimerically expresses a molecular adjuvant heat-labile enterotoxin B subunit(LTB)protein on the surface of the RABV particles.Immunogenicity in vivo was found to be promoted by rCVS11-LTB through the activation of dendritic cells(DCs).Our results demonstrated that inactivated rCVS11-LTB was able to induce higher levels of virusneutralizing antibodies(VNAs)in both mice and dogs than the parent virus rCVS11,to enhance the cellular immune response and T cell immune memory in mice,and was also able to provide 100%protection in mice from lethal doses of rabies virus,indicating its potential as a safe and effective inactivated rabies vaccine candidate.Zhiyuan Gong Hailun Li Meichen Qian Yujie Bai Hongli Jin Jingxuan Sun Mengyao Zhang Cuicui Jiao Pei Huang Yuanyuan Li Haili Zhang Hualei Wang 2023Biosafety and Health2023,5,5:0
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