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| 1 | The operational seasonal forecasting of summer rainfall in China显示文摘 | Zhang Jijia Chen Xingfang | 1987 | Adv Atmos Sci1987，4，4： | 1 |
| 2 | Ginsenoside Rh2 inhibits breast cancer cell growth via ERβ-TNFα pathway显示文摘Ginsenoside Rh2 is one of rare panaxidiols extracted from Panax ginseng and a potential estrogen receptor ligand that exhibits moderate estrogenic activity.However,the effect of Rh2 on growth inhibition and its underlying molecular mechanism in human breast cells are not fully understood.In this study,we tested cell viability by MTT and colony formation assays.Cell growth and cell cycle were determined to investigate the effect of ginsenoside Rh2 by flow cytometry.The expressions of estrogen receptors(ERs),TNFα,and apoptosis-related proteins were detected by qPCR and western blot analysis.The mechanisms of ERαand ERβaction were determined using transfection and inhibitors.Antitumor effect of ginsenoside Rh2 against MCF-7 cells was investigated in xenograft mice.Our results showed that ginsenoside Rh2 induced apoptosis and G1/S phase arrest in MCF-7 cells.Treatment of cells with ginsenoside Rh2 down-regulated protein levels of ERα,and up-regulated mRNA and protein levels of ERβand TNFα.We also found that ginsenoside Rh2-induced TNFαover-expression is through up-regulation of ERβinitiated by ginsenoside Rh2.Furthermore,ginsenoside Rh2 induced MCF-7 cell apoptosis via estrogen receptorβTNFαpathway in vivo.These results demonstrate that ginsenoside Rh2 promotes TNFα-induced apoptosis and G1/S phase arrest via regulation of ERβ. | Kunjian Peng Tiao Luo Jijia Li Jingjia Huang Zizeng Dong Jia Liu Chaoqiong Pi Zizeng Zou Qin Gu Ousheng Liu Jian-Ting Zhang Zhi-Yong Luo | 2022 | Acta Biochimica et Biophysica Sinica2022，54，5： | 1 |
| 3 | Genetic engineering of Streptomyces bingchenggensis to produce milbemycins A3/A4 as main components and eliminate the biosynthesis of nan- ehangmycin显示文摘 | ZHANG Ji AN Jing WANG Jijia | 2013 | Applied Microbiology and Biotechnology2013，97，10： | 1 |
| 4 | Typicality effects in picture-word interferenceparadigm: an evaluation of the response exclusion hypothesis显示文摘 | Yanhong Fang Jijia Zhang Guanhai Yin Senqi Hu & Entao Zhang | 2015 | Scandinavian Journal of Pscyology2015，，3： | 1 |
| 5 | A electro-deposition process for fabrication of biomimetic super-hydrophobic surface and its corrosion resistance on magnesium alloy显示文摘 | Yan Liu Xiaoming Yin Jijia Zhang Sirong Yu Zhiwu Han Luquan Ren | 2014 | Electrochimica Acta2014，，： | 1 |
| 6 | The operational seasonal forecasting of the summer rainfall in China显示文摘 | Jijia Zhang Xingfang Chen | 1987 | Advances in Atmospheric Sciences1987，，3： | 1 |
| 7 | Power analysis for stratified cluster randomisation trials with cluster size being the stratifying factor显示文摘Stratified cluster randomisation trial design is widely employed in biomedical research and cluster size has been frequently used as the stratifying factor.Conventional sample size calculation methods have assumed the cluster sizes to be constant within each stratum,which is rarely true in practice.Ignoring the random variability in cluster size leads to underestimated sample sizes and underpowered clinical trials.In this study,we proposed to directly incorporate the variability in cluster size(represented by coefficient of variability)into sample size calculation.This approach provides closed-form sample size formulas,and is flexible to accommodate arbitrary randomisation ratio and varying numbers of clusters across strata.Simulation study shows that the proposed approach achieves desired power and type I error over a wide spectrum of design configurations,including different distributions of cluster sizes.An application example is presented. | Jijia Wang Song Zhang Chul Ahn | 2017 | Statistical Theory and Related Fields2017，1，1： | 0 |
| 8 | Sample size and power analysis for stepped wedge cluster randomised trials with binary outcomes显示文摘In stepped wedge cluster randomised trials(SW-CRTs),clusters of subjects are randomly assigned to sequences,where they receive a specific order of treatments.Compared to conventional cluster randomised studies,one unique feature of SW-CRTs is that all clusters start from control and gradually transition to intervention according to the randomly assigned sequences.This feature mitigates the ethical concern of withholding an effective treatment and reduces the logistic burden of implementing the intervention at multiple clusters simultaneously.This feature,however,presents challenges that need to be addressed in experimental design and data analysis,i.e.,missing data due to prolonged follow-up and complicated correlation structures that involve between-subject and longitudinal correlations.In this study,based on the generalised estimating equation(GEE)approach,we present a closed-form sample size formula for SW-CRTs with a binary outcome,which offers great flexibility to account for unbalanced randomisation,missing data,and arbitrary correlation structures.We also present a correction approach to address the issue of under-estimated variance by GEE estimator when the sample size is small.Simulation studies and application to a real clinical trial are presented. | Jijia Wang Jing Cao Song Zhang Chul Ahn | 2021 | Statistical Theory and Related Fields2021，5，2： | 0 |
| 9 | Review of teachers’mental health research in China since 1994显示文摘通过对1994–2005年间中国教师心理健康的研究状况的分析,可以发现,以往教师心理健康的研究存在研究类型和研究方法单一、研究工具单一以及研究水平低等问题。比较而言,高校教师心理不健康检出率最高,与幼儿教师和中小学教师间有显著差异;随着时代发展,教师心理不健康的检出率递增,特别是21世纪后增长很快;农村教师心理健康状况总体上比城镇教师差;40岁以上年龄段的教师心理健康状况显著差于其他年龄段,但30岁以下年龄段教师心理健康状况好于普通人群;女教师的心理健康状况总体上差于男教师。应关注教师的心理健康问题,着力提高教师心理健康研究的水平,开展深入的调查研究、严密的实验研究和高质量的质性研究。 | ZHANG Jijia LU Aitao | 2008 | Frontiers of Education in China2008，3，4： | 0 |
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