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| 1 | The Expression of Manganese Superoxide Dismutase Gene from Nelumbo nucifera Responds Strongly to Chilling and Oxidative Stresses显示文摘A manganese superoxide dismutase(Mn-SOD) gene,NnMSD1,was identified from embryonic axes of the sacred lotus(Nelumbo nucifera Gaertn.) . The NnMSD1 protein contains all conserved residues of the Mn-SOD protein family,including four consensus metal binding domains and a signal peptide for mitochondrial targeting. Southern blot analysis suggests the existence of two Mn-SOD genes in sacred lotus. NnMSD1 was highly expressed in developing embryonic axes during seed development,but appeared in cotyledons only at the early stage of development and became undetectable in the cotyledons during late embryogenesis. The expression of the NnMSD1 gene in germinating embryonic axes,in response to various stresses such as heat shock,chilling,and exposure to stress-related chemicals,was also studied. Heat shock strongly inhibited the expression of the NnMSD1 gene,whereas the NnMSD1 transcript level increased strongly in chilling stress treatment. An increase in expression was also highly induced by H2O2 in germinating embryonic axes. The results suggest that the expression pattern of the NnMSD1 gene differed between developing axes and cotyledons,and that the NnMSD1 gene expression responds strongly to chilling and oxidative stress. | Wen Li Lin Qi Xiaodong Lin Huhui Chen Zhanqi Ma Keqiang Wu Shangzhi Huang | 2009 | Journal of Integrative Plant Biology2009，51，3： | 6 |
| 2 | UV/H2O2 oxidation of tri(2-chloroethyl) phosphate: Intermediate products, degradation pathway and toxicity evaluation显示文摘Tri(2-chloroethyl) phosphate(TCEP) with the initial concentration of 5 mg/L was degraded by UV/H2O2 oxidation process. The removal rate of TCEP in the UV/H2O2 system was 89.1% with the production of Cl-and PO4^3- of 0.23 and 0.64 mg/L. The removal rate of total organic carbon of the reaction was 48.8% and the pH reached 3.3 after the reaction. The oxidative degradation process of TCEP in the UV/H2O2 system obeyed the first order kinetic reaction with the apparent rate constant of 0.0025 min^-1( R^2 = 0.9788). The intermediate products were isolated and identified by gas chromatography-mass spectrometer. The addition reaction of HO · and H2O and the oxidation reaction with H2O2 were found during the degradation pathway of 5 mg/L TCEP in the UV/H2O2 system. For the first time, environment risk was estimated via the 'ecological structure activity relationships' program and acute and chronic toxicity changes of intermediate products were pointed out. The luminescence inhibition rate of photobacterium was used to evaluate the acute toxicity of intermediate products. The results showed that the toxicity of the intermediate products increased with the increase of reaction time, which may be due to the production of chlorine compounds. Some measures should be introduced to the UV/H2O2 system to remove the highly toxic Cl-containing compounds, such as a nanofiltration or reverse osmosis unit. | Qiuyi Ji Huan He Zhanqi Gao Xiaohan Wang Shaogui Yang Cheng Sun Shiyin Li Yong Wang Limin Zhang | 2020 | Journal of Environmental Sciences2020，32，12： | 4 |
| 3 | Occurrence and distribution of geminiviruses in China显示文摘Geminiviruses are a group of plant viruses that cause severe diseases in many economically important crops worldwide, leading to devastating losses to agricultural production. Here we summarize the occurrence and distribution of geminiviruses in China,which provides valuable information for further epidemiological studies and supports the development of effective disease management strategies. | Fangfang Li Rui Qiao Zhanqi Wang Xiuling Yang Xueping Zhou | 2022 | Science China(Life Sciences)2022，65，8： | 3 |
| 4 | GenMuNN: A mutation-based approach to repair deep neural network models显示文摘Deep neural network(DNN)models have been widely used in e-commerce,games,auto-mobiles,manufacturing,and so on.Improper structure,parameters,activation function,or incorrect loss function of the DNN models may cause defects in performance or secu-rity.As a result,there are some researches that focus on repairing DNN such as MODE and Apricot.However,the cost of repairing is high or the repair may lead to overfit-ting.In order to solve this problem,we propose GenMuNN,which is a Mutation-Based Approach to Repair Deep Neural Network Models.First,it analyzes the importance of the weights of the neurons in each layer of the DNN model to the correctness of the final prediction results,and ranks the weights according to the influence on the prediction results of the DNN model.Second,mutation is performed to generate mutants based on the rank of weights,and genetic algorithms are used to select mutants for the next round of mutation until the stop condition is touched.Experiments are carried on a set of DNN models which are trained with the MNIST dataset.The experimental results show that GenMuNN can improve the accuracy of the DNN models. | Huanhuan Wu Zheng Li Zhanqi Cui Jianbin Liu | 2022 | International Journal of Modeling, Simulation, and Scientific Computing2022，13，2： | 1 |
| 5 | Transcriptome Analysis of Monozygotic Twin Brothers with Childhood Primary Myelofibrosis显示文摘Primary myelofibrosis(PMF) is a chronic myeloproliferative disorder in human bone marrow. Over 50% of patients with myelofibrosis have mutations in JAK2, MPL, or CALR. However, these mutations are rarely detected in children, suggesting a difference in the pathogenesis of childhood PMF. In this study, we investigated the response to drug treatment of a monozygotic twin pair with typical childhood PMF. The twin exhibited different clinical outcomes despite followingthe same treatment regimen. The transcriptomic profiles of patient samples after drug treatment(E2and Y2) were significantly different between the twin pair, which is consistent with the observation that the drug treatment was effective only in the younger brother, despite the twin being genetically identical. Bioinformatics analysis of the drug-responsive genes showed that the JAK-STAT pathway was activated in the cured younger brother, which is opposite to the pathway inhibition observed in adult PMF cases following treatment. Moreover, apoptosis and cell cycle processes were both significantly influenced by drug treatment in the sample of younger brother(Y2), implying their potential association with the pathogenesis of childhood PMF. Gene mutations in JAK2,MPL, or CALR were not observed; however, mutations in genes including SRSF2 and SF3B1 occurred in this twin pair with childhood PMF. Gene fusion events were extensively screened in the twin pair samples and the occurrence of IGLV2-14-IGLL5 gene fusion was confirmed. The current study reported at transcriptomic level the different responses of monozygotic twin brothers with childhood PMF to the same androgen/prednisone treatment regimen providing new insights into the potential pathogenesis of childhood PMF for further research and clinical applications. | Nan Ding Zhaojun Zhang Wenyu Yang Lan Ren Yingchi Zhang Jingliao Zhang Zhanqi Li Peihong Zhang Xiaofan Zhu Xiaojuan Chen Xiangdong Fang | 2017 | Genomics, Proteomics & Bioinformatics2017，15，1： | 1 |
| 6 | Dynamic Fracture Analysis of Functionally Gradient Materials with Two Cracks By Peridynamic Modeling显示文摘In the research,the dynamic fracture failure problem of functionally graded materials(FGMs)containing two pre-cracks was analyzed using a bond-based Peridynamic(PD)method numerical model.The two convergence of decreasing the area of PD horizon(δ-convergence)and uniform mesh refinement(m-convergence)were studied.The effects of both crack position and distance between two cracks on crack propagation pattern in FGMs plate under tensile loads are studied.Furthermore,the effects of different gradient patterns on the dynamic propagation of cracks in FGMs are also investigated.The simulate results suggest that the cracks positions and the distance between them can significantly influence the dynamic propagation of crack in FGMs.Gradient mode also has a certain effect on crack propagation,but the effect of specific gradient variation patterns on dynamic propagation of crack is finite. | Zhanqi Cheng Dongdong Jin Chengfang Yuan Le Li | 2019 | Computer Modeling in Engineering & Sciences2019，，11： | 1 |
| 7 | Strong dual-state emission of unsymmetrical and symmetrical thiazolothiazole-bridged imidazolium salts显示文摘A novel thiazolothiazole-bridged imidazole derivative(1) was found to exhibit blue fluorescence in gaseous state or in methanol and yellow fluorescence in solid state. The N-alkylation of imidazole subunit(s) in 1 using n-propyl iodide generated unsymmetrically or symmetrically alkylated thiazolothiazolebridged imidazolium salts with good water solubility and remarkably strong emission in solution. Furthermore, the replacement of iodide counter-anion by triflate or bis(trifluoromethane sulfonyl)imide achieved remarkably strong emission in solid state and in solution as well as good water solubility. The strong fluorescence of dicationic salts with triflate and NTf_(2)^(-)counter-anions in solid state can be ascribed to their twisted and rigid structures induced by interionic C-H···F hydrogen bonding. | Puhui Xie Ying Zhou Xiaochuan Li Xiaojing Liu Lijie Liu Zhanqi Cao Jianji Wang Xin Zheng | 2023 | Chinese Chemical Letters2023，34，3： | 1 |
| 8 | CAD/CAM ALGORITHM OF RULED SURFACE BASED ON LINE GEOMETRY显示文摘CAD/CAMALGORITHMOFRULEDSURFACEBASEDONLINEGEOMETRY①HuZhanqiCuiYunqiQiaoLeiLiYupengMechanicalEngineeringInstitute,YanshanUniver... | Hu Zhanqi Cui Yunqi Qiao Lei Li Yupeng Mechanical Engineering Institute, Yanshan University | 1998 | Chinese Journal of Mechanical Engineering1998，11，3： | 0 |
| 9 | The Application of Electron-Beam Welding in Pellet Mold Preparation显示文摘This paper provides insight into the application of electron-beam welding in pellet mold preparation,highlighting the importance of the combination of electron-beam welding and pellet mold preparation in the fields of microstructure joining and micro-and nanostructure preparation.Precise material joining and microstructure fabrication can be achieved by the precise control of electron-beam welding and the shape adjustment of pellet molds.These applications hold significant potential in the modern industrial field,providing robust support for the development of new materials and the growth of the petrochemical industry.This paper asserts that in the future,the ongoing development of electron-beam welding and pelletizing template technology will unlock new possibilities in the field of petrochemicals,fostering progress in science and technology. | Zhanqi Liu Mingjiang Bian Kun Li Qianru Lin | 2023 | Journal of Electronic Research and Application2023，7，6： | 0 |
| 10 | GPIBase:A comprehensive resource for geminivirus-plant-insect research显示文摘Dear Editor,As one of the most widespread and destructive families of plant viruses,Geminiviridae,named for the twinned icosahedral particles of virus members in the family,poses a serious threat to agricultural production worldwide.Transmitted by various homopterans insects such as whiteflies,leafhoppers,aphids,and treehoppers,geminiviruses infect,in addition to wild plants,vegetable,root,and fiber crops,thus causing important losses around the globe(Hanley-Bowdoin et al.,2013;Li et al.,2022). | Yaqin Wang Yang Mei Chenlu Su Zuoqi Wang Fangfang Li Tao Hu Zhanqi Wang Shusheng Liu Fei Li Xueping Zhou | 2023 | Molecular Plant2023，16，4： | 0 |
| 11 | An acid-base responsive linear-cyclic polymer rotaxane molecular shuttle with fluorescence signal output显示文摘The preparation of intelligent-responsive materials with controllable topology structure has long been a significant objective for chemists in the field of materials science. In this paper, we designed and prepared a linear-cyclic reversible topological structure polymer based on the bistable [1]rotaxane molecular shuttle. A ferrocene-functionalized [1]rotaxane and naphthalimide fluorophore group are introduced into the both ends of the polymer, which exhibit distance-induced photo-electron transfer effect. The structural transformation between linear and cyclic state of polymer is demonstrated by simple acid-base stimuli, accompanying visual fluorescence changes. The transformation process was characterized by 1H NMR spectra and fluorescence spectra. This work provides a novel strategy to construct functionalized polymers with topological structure. | Zhanqi Cao Dongpu Wu Mengzhen Li Fan Yang Zhikai Li Wankai An Song Jiang Xin Zheng Caoyuan Niu Dahui Qu | 2022 | Chinese Chemical Letters2022，33，3： | 0 |
| 12 | ANALYSIS OF TWO DISSIMILAR FUNCTIONALLY GRADED STRIPS CONTAINING INTERFACE CRACK UNDER PLANE DEFORMATION显示文摘In this paper the plane elasticity problem of two bonded dissimilar functionally graded strips containing an interface crack is studied.The governing equation in terms of Airy stress function is formulated and exact solutions are obtained for several special variations of material properties in Fourier transformation domain.The mixed boundary problem is reduced to a system of singular integral equations that are solved numerically.Numerical results show that fracture toughness of materials can be greatly improved by graded variation of elastic modulus and the influence of the specific form of elastic modulus on the fracture behavior of FGM is limited. | Haiyang Li Xingtao Zhang Zhanqi Cheng Danying Gao Zheng Zhong | 2013 | Acta Mechanica Solida Sinica2013，26，1： | 0 |
| 13 | Primitive Neuroectodermal Tumor as the Second Malignant Neoplasm in a Long-Term Survivor Child of Acute Lymphoblastic Leukemia: A Case Report显示文摘Acute lymphoblastic leukemia(ALL)is a common pediatric cancer.The second malignant neoplasms(SMNs)in long-term survivors of pediatric ALL are relatively rare.Herein we report a 10-year-old girl who was diagnosed as primitive neuroectodermal tumor(PNET)5 years after the initial diagnosis of ALL with radiotherapy・free treatment.PNET is an exceedingly rare neoplasm in SMNs of survivors of childhood ALL.It is predisposed to be misdiagnosed and the pathogenesis is unclear.The outcome is poor.Long-term follow-up is necessary for the survival children of ALL. | Aoli Zhang Xiaojuan Chen Zhanqi Li Xiaofan Zhu | 2020 | Chinese Medical Sciences Journal2020，35，2： | 0 |
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