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32篇 您的检索式:作者名="Zhen D C"
    题名 作者 年代 出处 被引量
1Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency显示文摘Pluripotency,一个细胞的能力区分并且产生所有胚胎的系,定义象胚胎的茎(ES ) 那样的哺乳动物的细胞类型的一个小数字细胞。当它通常被保持了时,那 pluripotency 是 transcriptional 的产品激活并且维持关键干细胞基因的表达式的规章的网络,积累的证据在建立并且保卫 ES 房间的 pluripotency 为 epigenetic 进程正在指向一个关键角色,象维持区分的房间类型的身份一样。以便更好在 pluripotency 理解 epigenetic 机制的角色,我们检验了在经历区别进一个 mesendodermal 系的人的 ES 房间(hESCs ) 染色体宽的染色质修正的动力学。我们发现在倡导者的染色质修正在区别期间仍然保持大部分不变,除了在在在 H3K27 的 acetylation 和 methylation 之间的一个动态开关标记在基因表示的激活和 silencing 之间的转变的倡导者的一个小数字,建议在在大多数差别上的房间命运承诺的一个层次表示了基因。我们也在 50 000 潜在的 enhancers 上印射,并且在染色质修正,特别 H3K4me1 和 H3K27ac 观察了大得多的动力学,它与他们的潜在的目标基因的表示相关。这些 enhancers 的进一步的分析揭示了 pluripotency 和可以在 hESCs 授与发展胜任的一个平衡状态的一口染色质签名陈述语气的潜在地关键的 transcriptional 管理者。我们的结果提供在定义 enhancers 和 pluripotency 支持染色质修正的角色的新证据。R David Hawkins Gary C Hon Chuhu Yang Jessica E Antosiewicz-Bourget Leonard K Lee Que-Minh Ngo Sarit Klugman Keith A Ching Lee E Edsall Zhen Ye Samantha Kuan Pengzhi Yu Hui Liu Xinmin Zhang Roland D Green Victor V Lobanenkov Ron Stewart James A Thomson Bing Ren 2011Cell Research2011,21,10:6
2Preparation of Ir/IrOx pH eleetrode based on melt-oxidation and its response mechanism investigation 显示文摘Chen D C Zhen J S Fu C Y 2003Transactions Nonferrous Metals2003,13,1:1
3Physicochemical and antioxidant properties of buckwheatFagopyrum esculentum Moench) protein hydroIysates显示文摘Tang C H Peng J Zhen D W 2009Food Chemistry2009,115,:1
4Dynamics analysis of the Baiyun sag in the Pearl River Mouth Basin, north of the South China sea显示文摘ZHEN S ZHIHONG Z DI Z ZHOU D PANG X HUAN C CHEN C HE M XU H 2008Aeta Geologica Sinica (EnglishEdition)2008,82,1:1
5Devel- opment and application of a muhimodal contrast ggent for SPECT/CT hybrid imaging 显示文摘Jason M C Lawrence W D Zhen W Z etal 2011Bioconjug Chem2011,22,:1
6Physicochemical and antioxidant properties of buckwheat (Fagopyrum esculentum Moench) protein hydrolysates显示文摘Tang C H Peng J Zhen D W 2009Food Chemistry2009,115,:1
7Arrhythmia caused by intravenous infusion of octreotide显示文摘ZHEN Y C XIE D X 2001ADRJ2001,3,2:1
8Physicochemical and antioxidant properties of buckwheat (Fagopyrum esculentum Moench) protein hydrolysates 显示文摘TANG C H PENG J ZHEN D W 2009Food Chemistry2009,,115:1
9Microstructure evolution of adiabatic shear bands in AM60B magnesium alloy under ballistic impact显示文摘Zhen L Zou D L Xu C Y 2010Mater Sci Eng A2010,527,2122:1
10Mesozoic tectonic evolution of the Yanshan fold and thrust belt with emphasis on Hebei and Liaoning Provinces,northern China显示文摘Davis G A Zhen Y D Wang C 2001Geological Society of America Memoir2001,194,:1
11Physieochemieal and antioxidant properties of buckwheat (Fagopyrum esculentum Moench) protein hydrolysates显示文摘Tang C H Peng J Zhen D W 2009115 : 672-6782009,115,:1
12Applying value transfer method for eco-service valuation in China 显示文摘XIE G D ZHEN L LU C X 2010Journal of Resource and Ecology2010,1,1:1
13A New Adaptive Muhiresolution Noise-filtering Approach for SAR Interferometric Phase Images 显示文摘Bin C Diannong L Zhen D 2008IEEE Trans on GRSL2008,5,2:1
14Reliability analysis for the consecutive-k-out- of-n: F system with repairmen taking multiple vacations显示文摘Li Y Zhen D C 2012Applied Mathematical Modeling2012,37,9:1
15Multiple Outbreaks of Acute Hemorrhagic Conjunctivitis due to a Variant of Coxsackievirus A24:Guangdong,China,2007显示文摘Wu D Ke C W Mo Y L Sun L M Li H Chen Q X Zou L R Fang L Huang P Zhen H Y 2008J Med Virol2008,80,10:1
16Preparation of free-standing nanowire arrays on conductive substrates显示文摘LIANG Y Q ZHEN C G ZOU D C 2004J Am Chem Soc2004,126,16:1
17The metabolic respon- ses and acid base status after feeding, exhaustive exer- cise ,and both feeding and exhaustive exercise in Chinese catfish (Silurus asotus Linnaeus) 显示文摘Ke G L Zhen D C Jiang L P 2010Journal Comparative Physiology B2010,180,5:1
18Physieochemical and antioxi- dant properties of buekwheat (Fagopyrum esculentum Moench)protein hydrolysates显示文摘Tang C H Peng J Zhen D W 2009Food Chemistry2009,115,:1
19Fluorene-based oligomers for highly efficient and stable organic blue-light-emitting diodes 显示文摘ZHEN C G CHEN Z K LIU Q D 2009Advanced Materials2009,21,23:1
20Physicochemical and antioxidant properties of buckwheat Fagopyrum esculentum Moench) protein hydrolysates显示文摘Tang C H Peng J Zhen D W 2009Food Chemistry2009,115,:1
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