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| 1 | Analyses on the tectonic thermal evolution and influence factors in the deep-water Qiongdongnan Basin显示文摘To reveal the tectonic thermal evolution and influence factors on the present heat flow distribution, based on 154 heat flow data, the present heat flow distribution features of the main tectonic units are first analyzed in detail, then the tectonic thermal evolution histories of 20 profiles are reestablished crossing the main deep-water sags with a structural, thermal and sedimentary coupled numerical model. On the basis of the present geothermal features, the Qiongdongnan Basin could be divided into three regions: the northern shelf and upper slope region with a heat flow of 50–70 m W/m2, most of the central depression zone of 70–85 m W/m2, and a NE trending high heat flow zone of 85–105 m W/m2 lying in the eastern basin. Numerical modeling shows that during the syn-rift phase, the heat flow increases generally with time, and is higher in basement high area than in its adjacent sags. At the end of the syn-rift phase, the heat flow in the deepwater sags was in a range of 60–85 m W/m2, while in the basement high area, it was in a range of 75–100 m W/m2. During the post-rift phase, the heat flow decreased gradually, and tended to be more uniform in the basement highs and sags. However, an extensive magmatism, which equivalently happened at around 5 Ma, has greatly increased the heat flow values, and the relict heat still contributes about 10–25 m W/m2 to the present surface heat flow in the central depression zone and the southern uplift zone. Further analyses suggested that the present high heat flow in the deep-water Qiongdongnan Basin is a combined result of the thermal anomaly in the upper mantle, highly thinning of the lithosphere, and the recent extensive magmatism. Other secondary factors might have affected the heat flow distribution features in some local regions. These factors include basement and seafloor topography, sediment heat generation, thermal blanketing, local magmatic injecting and hydrothermal activities related to faulting and overpressure. | WANG Zhenfeng SHI Xiaobin YANG Jun HUANG Baojia SUN Zhen WANG Yahui JIANG Haiyan YU Chuanhai YANG Xiaoqiu | 2014 | Acta Oceanologica Sinica2014，33，12： | 22 |
| 2 | Enhancing Photocatalytic Performance of NH 2-UIO66 by Defective Structural Engineering显示文摘NH_(2)-UIO66(NU)is a promising photocatalyst for the reduction of Cr(VI)to low-toxic Cr(III)driven by visible light under ambient conditions.However,the main limitation in this process is the ineffi cient ligand to metal charge transfer(LMCT)of photo-excited electrons,which is caused by inherent energy gap(ΔE_(LMCT)).This study synthesized the defective NU(NUXH,where X is the molar equivalent of the modulator)with reducedΔE_(LMCT)through linkers removal via acid treatment.The electronic structure of NUX-H was systematically investigated,and the results indicated that the structural defects in NUX-H strongly altered the environment of the Zr atoms.Furthermore,they substantially lowered the energy of the unoccupied d orbitals(LUMO),which was benefi cial to effi cient LMCT,resulting in an improved photocatalytic activity of NUX-H toward high-concentration(100 mg/L)Cr(VI)reduction.Compared to NU with defect-free structure,the reducing rate of Cr(VI)was increased by 47 times.This work introduced an alternative strategy in terms of designing effi cient photocatalysts for reducing Cr(VI)under ambient conditions. | Zhenmin Xu Jiazhen Cao Xiang Chen Liyi Shi Zhenfeng Bian | 2021 | Transactions of Tianjin University2021，27，2： | 2 |
| 3 | Changes of immunocytic phenotypes and functions from human colorectal adenomatous stage to cancerous stage: Update显示文摘 | Yanhong Shi Zhenfeng Li Wei Zheng Xia Liu Chenyi Sun Jann-Birger Laugsand Zhanju Liu Guanglin Cui | 2015 | Immunobiology2015，，10： | 1 |
| 4 | Conversion of lignin oil and hemicellulose derivative into high-density jet fuel显示文摘Synthesizing high-density fuel from lignocellulose can not only achieve green and low-carbon development,but also expand the feedstock source of hydrocarbon fuel.Here,we reported a route of producing high-density fuel from lignin oil and hemicellulose derivative cyclopentanol through alkylation and hydrodeoxygenation,HY with SiO_(2)/Al_(2)O_(3) molar ratio of 5.3 was screened as the alkylation catalyst in the reaction of model phenolic compounds and mixtures,and the reaction conditions were optimized to achieve conversion of phenolic compounds higher than 87%and selectivity of bicyclic and tricyclic products higher than 99%.Then two phenolic pools simulating the composition of two typic lignin oils were studied to validate the alkylation and analyze the competition mechanism of phenolic compounds in mixture system.Finally,real lignin oil from depolymerized of beech powder was tested,and notably80%of phenolic monomers in the oil were converted into fuel precursor.After hydrodeoxygenation,the alkylated product was converted to fuel blend with a density of 0.91 g/mL at 20℃and a freezing point lower than-60℃,very promising as high density fuel.This work provides a facile and energyefficient way of synthesizing high-performance jet fuel directly from lignocellulosic derivatives,which decreases processing energy consumption and improve the utilization rate of feedstock. | Sichao Yang Chengxiang Shi Zhensheng Shen Lun Pan Zhenfeng Huang Xiangwen Zhang Ji-Jun Zou | 2023 | Journal of Energy Chemistry2023，，2： | 1 |
| 5 | Direct transformation of dinitrogen:synthesis of N-containing organic compounds via N-C bond formation显示文摘N-containing organic compounds are of vital importance to lives.Practical synthesis of valuable N-containing organic compounds directly from dinitrogen(N2),not through ammonia(NH3),is a holy-grail in chemistry and chemical industry.An essential step for this transformation is the functionalization of the activated N2 units/ligands to generate N-C bonds.Pioneering works of transition metal-mediated direct conversion of N2 into organic compounds via N-C bond formation at metal-dinitrogen[N2-M]complexes have generated diversified coordination modes and laid the foundation of understanding for the N-C bond formation mechanism.This review summarizes those major achievements and is organized by the coordination modes of the[N2-M]complexes(end-on,side-on,end-on-side-on,etc.)that are involved in the N-C bond formation steps,and each part is arranged in terms of reaction types(N-alkylation,N-acylation,cycloaddition,insertion,etc.)between[N2-M]complexes and carbon-based substrates.Additionally,earlier works on one-pot synthesis of organic compounds from N2 via ill-defined intermediates are also briefed.Although almost all of the syntheses of N-containing organic compounds via direct transformation of N2 so far in the literature are realized in homogeneous stoichiometric thermochemical reaction systems and are discussed here in detail,the sporadically reported syntheses involving photochemical,electrochemical,heterogeneous thermo-catalytic reactions,if any,are also mentioned.This review aims to provide readers with an in-depth understanding of the state-of-the-art and perspectives of future research particularly in direct catalytic and efficient conversion of N2 into N-containing organic compounds under mild conditions,and to stimulate more research efforts to tackle this long-standing and grand scientific challenge. | Ze-Jie Lv Junnian Wei Wen-Xiong Zhang Ping Chen Dehui Deng Zhang-Jie Shi Zhenfeng Xi | 2020 | National Science Review2020，7，10： | 1 |
| 6 | Science with the 2.5-meter Wide Field Survey Telescope(WFST)显示文摘The Wide Field Survey Telescope(WFST) is a dedicated photometric surveying facility being built jointly by University of Science and Technology of China(USTC) and the Purple Mountain Observatory(PMO). It is equipped with a 2.5-meter diameter primary mirror, an active optics system, and a mosaic CCD camera with 0.73 gigapixels on the primary focal plane for highquality image capture over a 6.5-square-degree field of view. The installation of WFST near the summit of Saishiteng mountain in the Lenghu region is scheduled in summer of 2023, and the operation is planned to start three months later. WFST will scan the northern sky in four optical bands(u, g, r and i) at cadences from hourly/daily in the deep high-cadence survey(DHS) program, to semi-weekly in the wide field survey(WFS) program. During a photometric night, a nominal 30 s exposure in the WFS program will reach a depth of 22.27, 23.32, 22.84, and 22.31(AB magnitudes) in these four bands, respectively, allowing for the detection of a tremendous amount of transients in the low-z universe and a systematic investigation of the variability of Galactic and extragalactic objects. In the DHS program, intranight 90 s exposures as deep as 23(u) and 24 mag(g), in combination with target of opportunity follow-ups, will provide a unique opportunity to explore energetic transients in demand for high sensitivities, including the electromagnetic counterparts of gravitational wave events, supernovae within a few hours of their explosions,tidal disruption events and fast, luminous optical transients even beyond redshift of unity. In addition, the final 6-year co-added images, anticipated to reach g■25.8 mag in WFS or 1.5 mags deeper in DHS, will be of fundamental importance to general Galactic and extragalactic science. The highly uniform legacy surveys of WFST will serve as an indispensable complement to those of the Vera C. Rubin Observatory's Legacy Survey of Space and Time(LSST) that monitors the southern sky. | Tinggui Wang Guilin Liu Zhenyi Cai Jinjun Geng Min Fang Haoning He Ji-an Jiang Ning Jiang Xu Kong Bin Li Ye Li Wentao Luo Zhizheng Pan Xuefeng Wu Ji Yang Jiming Yu Xianzhong Zheng Qingfeng Zhu Yi-Fu Cai Yuanyuan Chen Zhiwei Chen Zigao Dai Lulu Fan Yizhong Fan Wenjuan Fang Zhicheng He Lei Hu Maokai Hu Zhiping Jin Zhibo Jiang Guoliang Li Fan Li Xuzhi Li Runduo Liang Zheyu Lin Qingzhong Liu Wenhao Liu Zhengyan Liu Wei Liu Yao Liu Zheng Lou Han Qu Zhenfeng Sheng Jianchun Shi Yiping Shu Zhenbo Su Tianrui Sun Hongchi Wang Huiyuan Wang Jian Wang Junxian Wang Daming Wei Junjie Wei Yongquan Xue Jingzhi Yan Chao Yang Ye Yuan Yefei Yuan Hongxin Zhang Miaomiao Zhang Haibin Zhao Wen Zhao | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，10： | 1 |
| 7 | Characteristics of overpressure distribution and its implication for hydrocarbon exploration in the Qiongdongnan Basin显示文摘 | Wanzhong Shi Yuhong Xie Zhenfeng Wang Xusheng Li Chuanxin Tong | 2013 | Journal of Asian Earth Sciences2013，，： | 1 |
| 8 | Study on the destabilization mixing in the flat plate photobioreactor by means of CFD显示文摘 | Su Zhenfeng Kang Ruijuan Shi Shaoyuan | 2010 | Biomass and Bioenergy2010，34，12： | 1 |
| 9 | Discussion on construction methods and precautions of building water supply and drainage显示文摘As an important construction link in the construction project,the quality of the water supply and drainage directly affects the overall quality of the construction project.Because of the strong function of the water supply and drainage project,the construction quality is easily affected by the construction method.For this reason,construction enterprises should attach importance to the mastery of water supply and drainage construction methods.And further understand the relevant precautions of construction water supply and drainage construction,in order to achieve the purpose of improving the quality of water supply and drainage construction. | Guoliang Yu Fan Yang Li Li Zhenfeng Li Zhenlong Shi | 2018 | Smart Construction Research2018，2，1： | 0 |
| 10 | Optimization of the Open Degree of Key Valves Based on Relative Entropy and Pipeline Leakage显示文摘Based on information entropy theory, the definition of relative entropy, and the relative entropy minimum principle, this study establishes a multi-objective optimization model for a key valve opening of an urban water distribution network(WDN). Each node pressure is taken as the main research object to reduce pipeline leakage. Moreover, genetic algorithm is applied in the proposed model to solve the key valve opening of the actual WDN in a city in southern China. Using the proposed model, the relevant decision variables of a WDN can be optimized to provide a new manner of network dispatching. | Feiyu Li Zhenfeng Shi Chenguang Wu Yixing Yuan Yan Zhu | 2017 | Transactions of Tianjin University2017，23，5： | 0 |
| 11 | Physiological and biomass partitioning shifts to water stress under distinct soil types in Populus deltoides saplings显示文摘土壤类型是影响植物分布和生产力的重要环境因素,但有关土壤环境异质性对植物抗逆性效应的研究非常缺乏。本研究以美洲黑杨(Populus deltoids)为对象,以3种典型土壤类型(红壤、黄壤和黄棕壤)为栽培基质,在控制实验条件下,经过三个月的干旱胁迫(25%田间持水量)处理,测定了不同处理条件下美洲黑杨的气体交换速率、抗氧化能力、氮代谢特征、生物量积累与分配特征。研究结果表明,在红壤和黄壤条件下,与对照(75%田间持水量)相比,干旱胁迫显著降低了美洲黑杨各器官的生物量、光合速率、叶片氮同化酶的活性,显著增加了叶片中过氧化氢、丙二醛和无机氮的含量。在黄棕壤条件下,干旱对美洲黑杨总生物量、光合速率、氮同化酶以及质膜完整性的负面影响较小,这与其维持较高的超氧化物歧化酶,过氧化物酶和过氧化氢酶的活性相关,也与其生物量分配模式(如提高根冠比)密切相关。由此可见,生长在黄棕壤条件下的美洲黑杨表现出较强的抗旱能力,这可能与其土壤母质中较高的土壤养分和良好的通气状况相关。因此,就土壤类型而言,与红壤和黄壤相比,黄棕壤提供的土壤环境条件有利于美洲黑杨的抗逆表现和栽培利用。 | Senlin Yang Jian Shi Lianghua Chen Jian Zhang Danju Zhang Zhenfeng Xu Jiujin Xiao Peng Zhu Yang Liu Tiantian Lin Li Zhang Hanbo Yang Yu Zhong | 2020 | Journal of Plant Ecology2020，13，5： | 0 |
| 12 | Supramolecular assembly of chloroplast NADH dehydrogenase-like complex with photosystem Ⅰfrom Arabidopsis thaliana显示文摘Cyclic electron transport/flow(CET/CEF)in chloroplasts is a regulatory process essential for the optimization of plant photosynthetic efficiency.A crucial CEF pathway is catalyzed by a membrane-embedded NADH dehydrogenase-like(NDH)complex that contains at least 29 protein subunits and associates with photosystem I(PSI)to form the NDH-PSI supercomplex.Here,we report the 3.9Åresolution structure of the Arabidopsis thaliana NDH-PSI(AtNDH-PSI)supercomplex.We constructed structural models for 26 AtNDH subunits,among which 11 are unique to chloroplasts and stabilize the core part of the NDH complex.In the supercomplex,one NDH can bind up to two PSI-light-harvesting complex I(PSI-LHCI)complexes at both sides of its membrane arm.Two minor LHCIs,Lhca5 and Lhca6,each present in one PSI-LHCI,interact with NDH and contribute to supercomplex formation and stabilization.Collectively,our study reveals the structural details of the AtNDH-PSI supercomplex assembly and provides a molecular basis for further investigation of the regulatory mechanism of CEF in plants. | Xiaodong Su Duanfang Cao Xiaowei Pan Lifang Shi Zhenfeng Liu Luca Dall’Osto Roberto Bassi Xinzheng Zhang Mei Li | 2022 | Molecular Plant2022，15，3： | 0 |
| 13 | Glutamine metabolic microenvironment drives M2 macrophage polarization tomediate trastuzumab resistance in HER2-positive gastric cancer显示文摘Background:Trastuzumab is a first-line targeted therapy for human epidermal growth factor receptor-2(HER2)-positive gastric cancer.However,the inevitable occurrence of acquired trastuzumab resistance limits the drug benefit,and there is currently no effective reversal measure.Existing researches on the mechanism of trastuzumab resistance mainly focused on tumor cells themselves,while the understanding of the mechanisms of environment-mediated drug resistance is relatively lacking.This study aimed to further explore the mechanisms of trastuzumab resistance to identify strategies to promote survival in these patients.Methods:Trastuzumab-sensitive and trastuzumab-resistant HER2-positive tumor tissues and cells were collected for transcriptome sequencing.Bioinformatics were used to analyze cell subtypes,metabolic pathways,and molecular signaling pathways.Changes in microenvironmental indicators(such as macrophage,angiogenesis,and metabolism)were verified by immunofluorescence(IF)and immunohistochemical(IHC)analyses.Finally,a multi-scale agent-based model(ABM)was constructed.The effects of combination treatment were further validated in nude mice to verify these effects predicted by the ABM.Results:Based on transcriptome sequencing,molecular biology,and in vivo experiments,we found that the level of glutamine metabolism in trastuzumabresistant HER2-positive cells was increased,and glutaminase 1(GLS1)was significantly overexpressed.Meanwhile,tumor-derived GLS1 microvesicles drove M2macrophage polarization.Furthermore,angiogenesis promoted trastuzumab resistance.IHC showed high glutamine metabolism,M2 macrophage polarization,and angiogenesis in trastuzumab-resistant HER2-positive tumor tissues from patients and nudemice.Mechanistically,the cell division cycle 42(CDC42)promoted GLS1 expression in tumor cells by activating nuclear factor kappa-B(NF-κB)p65 and drove GLS1microvesicle secretion through IQmotif-containing GTPase-activating protein 1(IQGAP1).Based on the ABM and in vivo experiments,we confirmed that the combination of anti-glutamine metabolism,anti-angiogenesis,and pro-M1 polarization therapy had the best effect in reversing trastuzumab resistance in HER2-positive gastric cancer.Conclusions:This study revealed that tumor cells secrete GLS1 microvesicles via CDC42 to promote glutamine metabolism,M2 macrophage polarization,and pro-angiogenic function of macrophages,leading to acquired trastuzumab resistance in HER2-positive gastric cancer.A combination of anti-glutamine metabolism,anti-angiogenesis,and pro-M1 polarization therapy may provide a new insight into reversing trastuzumab resistance. | Xingbin Hu Zhenfeng Ma Beibei Xu Shulong Li Zhiqi Yao Bishan Liang Jiao Wang Wangjun Liao Li Lin Chunling Wang Siting Zheng Qijing Wu Qiong Huang Le Yu Fenghua Wang Min Shi | 2023 | Cancer Communications2023，43，8： | 0 |
| 14 | Seismic Inversion Technical Scheme and Application for Tight Clastic Reservoirs显示文摘 | Liu Zhenfeng Dong Ning Zhang Yonggui Wang Jianbo Shi Lei | 2012 | 石油地球物理勘探2012，47，A02： | 0 |
| 15 | Discussion on construction methods and precautions of building water supply and drainage显示文摘As an important construction link in the construction project, the quality of the water supply and drainage directly affects the overall quality of the construction project. Because of the strong function of the water supply and drainage project, the construction quality is easily affected by the construction method. For this reason, construction enterprises should attach importance to the mastery of water supply and drainage construction methods. And further understand the relevant precautions of construction water supply and drainage construction, in order to achieve the purpose of improving the quality of water supply and drainage construction. | Guoliang Yu Fan Yang Li Li Zhenfeng Li Zhenlong Shi | 2018 | Smart Construction Research2018，2，2： | 0 |
| 16 | The expression of miR-155 and miR-181 in gastric cancer and their effects on clinical parameters and prognostic value显示文摘Objective The aim of this study was to investigate the expression and clinical significance of miR-155 and miR-181 in gastric cancer.Methods Sixty-eight patients with gastric cancer and 80 healthy volunteers were selected as subjects.Serum samples of patients and volunteers were collected to detect miR-155 and miR-181 expression levels in serum and tumor tissues.Results miR-155 and miR-181 serum levels were significantly higher in patients with gastric cancer than those in the control group(P<0.05).miR-155 and miR-181 expression levels in gastric cancer tissues were 16.74±4.29 and 12.17±3.26,respectively and 3.42±0.39) and 3.06±0.69 in paracancerous tissues,respectively,and they were 1.22±0.21 and 1.08±0.35 in normal tissues,respectively.miR-155 and miR-181 expression levels in cancer tissues were significantly higher than adjacent tissues,and they were lowest in normal tissues(P<0.05).High miR-155 and miR-181 expression had significant effects on differentiation,T stage,lymph node metastasis,and clinical stage(P<0.05).Cox multivariate analysis showed that onset,T stage,clinical stage,differentiation degree,lymph node metastasis,miR-155,and miR-181 were independent risk factors for prognosis of patients with gastric cancer.Conclusion Serum miR-155 and miR-181 have a diagnostic value in gastric cancer,and they are strong signals of poor prognosis. | Zhenfeng Shi Shuchun Lin Xiaorong Tang Hongli Zheng Fei Wang Wudong Tao | 2019 | Oncology and Translational Medicine2019，5，6： | 0 |
| 17 | Synthesis of pyrimidines from dinitrogen and carbon显示文摘The element nitrogen and nitrogenous compounds are vital to life.The synthesis of nitrogen-containing compounds using dinitrogen as the nitrogen source,not through ammonia,is of great interest and great value but remains a grand challenge.Herein,we describe a strategy to realize this transformation by combining the heterogeneous approach with the homogeneous methodology.The N_(2)molecule was first fixed with carbon and LiH through a one-pot heterogeneous process,forming Li_(2)CN_(2)as an’activated’nitrogen source with high efficiency.Then subsequent homogeneous treatments of Li_(2)CN_(2)to construct the organic synthon carbodiimide and the RNA/DNA building block pyrimidines were fulfilled.By using^(15)N_(2)as the feedstock,their corresponding^(15)N-labeled carbodiimide and pyrimidines were readily obtained.This homogeneous-heterogeneous synergy strategy will open a new chapter for N_(2)transformation. | Xianghui Shi Qianru Wang Chao Qin Li-Jun Wu Yuanjin Chen Gao-Xiang Wang Yongli Cai Wenbo Gao Teng He Junnian Wei Jianping Guo Ping Chen Zhenfeng Xi | 2022 | National Science Review2022，9，12： | 0 |
| 18 | Direct conversion of N_(2) and O_(2):status,challenge and perspective显示文摘As key components of air,nitrogen(N_(2))and oxygen(O_(2))are the vital constituents of lives.Synthesis of NO_(2),and C-N-O organics direct from N_(2) and O_(2),rather than from an intermediate NH_(3)(known as the Haber-Bosch process),is tantalizing.However,the extremely strong N≡N triple bond(945 kJ mol-1)and the nonpolar stable electron configuration of dinitrogen lead to its conversion being extensively energy demanding.The further selective synthesis of high-value C-N-O organics directly from N_(2),O_(2) and C-containing molecules is attractive yet greatly challenging from both scientific and engineering perspectives.Enormous efforts have been dedicated to the direct conversion of N2 and O2 via traditional and novel techniques,including thermo chemical,plasma,electrochemical,ultrasonic and photochemical conversion.In this review,we aim to provide a thorough comprehension of the status and challenge of the direct conversion of N2,O2 and C-containing molecules(particularly N2 and O2).Moreover,we will propose some future perspectives to stimulate more inspiration from the scientific community to tackle the scientific and engineering challenges. | Di Li Lingxing Zan Shiming Chen Zhang-Jie Shi Ping Chen Zhenfeng Xi Dehui Deng | 2022 | National Science Review2022，9，12： | 0 |
| 19 | Modeling a stochastic avian influenza model under regime switching and with human-to-human transmission显示文摘In this paper,we investigate the stochastic avian influenza model with human-to-human transmission,which is disturbed by both white and telegraph noises.First,we show that the solution of the stochastic system is positive and global.Furthermore,by using stochastic Lyapunov functions,we establish sufficient conditions for the existence of a unique ergodic stationary distribution.Then we obtain the conditions for extinction.Finally,numerical simulations are employed to demonstrate the analytical results. | Zhenfeng Shi Xinhong Zhang | 2020 | International Journal of Biomathematics2020，13，7： | 0 |
| 20 | Advances in electrochemical transformation of N_(2)using molecular catalysts显示文摘The conversion of N_(2)to NH_(3)holds great importance due to the essential role of NH_(3)in fertilizer production,energy storage and the synthesis of key industrial chemicals.Development of novel methods for N_(2)transformation is a worthwhile goal and researchers have turned their attention to electrochemical N_(2)reduction as a potentially sustainable solution.The development of molecular electrocatalysts has gained considerable momentum over the last decades,and this review focuses on the advances and challenges in the field of molecular electrochemical nitrogen fixation and aims to inspire further research into the realm of nitrogen fixation chemistry from an electrochemical perspective. | Qiong Yuan Junnian Wei Dehui Deng Zhang-Jie Shi Ping Chen Zhenfeng Xi | 2023 | Science China Chemistry2023，66，10： | 0 |
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