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7篇 您的检索式:作者名="Zhenjie Fu"
    题名 作者 年代 出处 被引量
1Skeletal muscle mitochondrial remodeling in exercise and diseases显示文摘Zhenji Gan Tingting Fu Daniel R Kelly Rick B. Vega 2018Cell Research2018,28,10:25
2Sacrificial microgel‑laden bioink‑enabled 3D bioprinting of mesoscale pore networks显示文摘Three-dimensional(3D)bioprinting is a powerful approach that enables the fabrication of 3D tissue constructs that retain complex biological functions.However,the dense hydrogel networks that form after the gelation of bioinks often restrict the migration and proliferation of encapsulated cells.Herein,a sacrificial microgel-laden bioink strategy was designed for directly bioprinting constructs with mesoscale pore networks(MPNs)for enhancing nutrient delivery and cell growth.The sacrificial microgel-laden bioink,which contains cell/gelatin methacryloyl(GelMA)mixture and gelled gelatin microgel,is first thermo-crosslinked to fabricate temporary predesigned cell-laden constructs by extrusion bioprinting onto a cold platform.Then,the construct is permanently stabilized through photo-crosslinking of GelMA.The MPNs inside the printed constructs are formed after subsequent dissolution of the gelatin microgel.These MPNs allowed for effective oxygen/nutrient diffusion,facilitating the generation of bioactive tissues.Specifically,osteoblast and human umbilical vein endothelial cells encapsulated in the bioprinted large-scale constructs(≥1 cm)with MPNs showed enhanced bioactivity during culture.The 3D bioprinting strategy based on the sacrificial microgel-laden bioink provided a facile method to facilitate formation of complex tissue constructs with MPNs and set a foundation for future optimization of MPN-based tissue constructs with applications in diverse areas of tissue engineering.Lei Shao Qing Gao Chaoqi Xie Jianzhong Fu Meixiang Xiang Zhenjie Liu Liulin Xiang Yong He 2020Bio-Design and Manufacturing2020,3,1:3
3Carotid Artery Stenting Versus Carotid Endarterectomy: Systematic Review and Meta-Analysis显示文摘Zhenjie Liu Zhenyu Shi Yuqi Wang Bin Chen Ting Zhu Yi Si Weiguo Fu 2009World Journal of Surgery2009,,3:1
4The antithrombotic effect of a novel hirudin derivative after reconstruction of carotid artery in rabbits显示文摘Wei Feng Lu Wei Mo Zhenjie Liu Wei Guo Fu Da Qiao Guo Yu Qi Wang Hou Yan Song 2010Thrombosis Research2010,,4:1
5Fluorous Metal–Organic Frameworks with Unique Cage-in-Cage Structures Featuring Fluorophilic Pore Surfaces for Efficient C_(2)H_(2)/CO_(2)Separation显示文摘The similarities in molecular size and physical properties of acetylene(C_(2)H_(2))and carbon dioxide(CO_(2))produce a formidable challenge for their separation.Herein,we report two isoreticular fluorinated metal–organic frameworks(MOFs),labeled as JXNU-11(Fe2M)(M=Ni and Co),featuring unique octahedral cages encapsulated by cuboctahedral cages.JXNU-11(Fe_(2)Ni)shows a record high C_(2)H_(2)-capture amount of 4.8mmol g−1 and a long C_(2)H_(2)/CO_(2)breakthrough interval time of 55 min g^(−1)in an actual breakthrough experiment based on the equimolar C_(2)H_(2)/CO_(2)mixture under ambient conditions,indicating a high-performance material for C_(2)H_(2)capture andC_(2)H_(2)/CO_(2)separation.Xing-Ping Fu Yu-Ling Wang Xue-Feng Zhang Zhenjie Zhang Chun-Ting He Qing-Yan Liu 2022CCS Chemistry2022,4,10:1
6pPeOp inhibits HGC-27 cell proliferation,migration and invasion by upregulating miR-30b-5p and down-regulating the Rac1/Cdc42 pathway显示文摘Gastric cancer is the fifth most frequently occurring and the fourth most lethal malignant cancer worldwide.A bioactive protein(pPeOp)from Omphalia lapidescens exhibits significant inhibitory effects on gastric cancer cells.miRNA deep sequencing analysis shows that miR-30b-5p is significantly upregulated in HGC-27 cells treated with pPeOp.Verification results show that the expression level of miR-30b-5p is significantly increased in HGC-27 cells after pPeOp treatment.Additionally,miR-30b-5p is significantly downregulated in clinical gastric cancer tissues compared to that in adjacent normal tissues.Following pPeOp treatment and/or transfection with miR-30b-5p mimic,the proliferation,migration,and invasion of HGC-27 cells are significantly impaired.Immunofluorescence microscopy shows that pPeOp and/or miR-30b-5p destroy(s)microfilaments and microstructures and inhibit(s)the formation of pseudopodia.Bioinformatics analysis,dual-luciferase reporter assay,and western blot analysis confirm that miR-30b-5p downregulates Rac1/Cdc42 expression and activation by targeting RAB22A.Available data indicate that miR-30b-5p plays an anti-gastric cancer role in mediating pPeOp.pPeOp upregulates miR-30b-5p expression,which in turn inhibits RAB22A expression,resulting in a reduction in the expression and activation of Rac1 and Cdc42 and their downstream targets,thus destroying the cytoskeletal structure and inhibiting the proliferation,migration,and invasion of cancer cells.Wenjun Xu Zhenjie Fu Yuqin Xu Man Hei Cheung Yan Chen Meiai Lin Hang Wen Hang Lv Chun Liang Jianshu Lou Yitao Chen 2022Acta Biochimica et Biophysica Sinica2022,54,12:0
7Recent Advancements in Photoelectrochemical Water Splitting for Hydrogen Production显示文摘Sunlight is the most abundant and inexhaustible energy source on earth.However,its low energy density,dispersibility and intermittent nature make its direct utilization with industrial relevance challenging,suggesting that converting sunlight into chemical energy and storing it is a valuable measure to achieve global sustainable development.Carbon–neutral,clean and secondary pollution-free solar-driven water splitting to produce hydrogen is one of the most attractive avenues among all the current options and is expected to realize the transformation from dependence on fossil fuels to zero-pollution hydrogen.Artificial photosynthetic systems(APSs)based on photoelectrochemical(PEC)devices appear to be an ideal avenue to efficiently achieve solar-to-hydrogen conversion.In this review,we comprehensively highlight the recent developments in photocathodes,including architectures,semiconductor photoabsorbers and performance optimization strategies.In particular,frontier research cases of organic semiconductors,dye sensitization and surface grafted molecular catalysts applied to APSs based on frontier(molecular)orbital theory and semiconductor energy band theory are discussed.Moreover,research advances in typical photoelectrodes with the metal–insulator–semiconductor(MIS)architecture based on quantum tunnelling are also introduced.Finally,we discuss the benchmarks and protocols for designing integrated tandem photoelectrodes and PEC systems that conform to the solar spectrum to achieve high-efficiency and cost-effective solar-to-hydrogen conversion at an industrial scale in the near future.Yibo Zhao Zhenjie Niu Jiwu Zhao Lan Xue Xianzhi Fu Jinlin Long 2023Electrochemical Energy Reviews2023,6,1:0
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