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| 1 | Disease profile and plasma neutralizing activity of postvaccination Omicron BA.1 infection in Tianjin,China:a retrospective study显示文摘Dear Editor,SARS-CoV-2 Omicron variant BA.1 first emerged on the Chinese mainland on January 8,2022,in Tianjin and caused a large wave of infections.1 Four rounds of mass testing of its~14 million residents were launched on January 9,12,15,and 20,respectively.As of February 7,2022,a total of 430 individuals were tested positive for Omicron BA.1,with no new infections detected for the following 16 days.In the Chinese mainland,the most delivered vaccines are inactivated vaccines.As of January 8,2022,up to 93.2%of Tianjin’s residents had been vaccinated with at least one dose.2 We investigated the protection conferred by vaccination against Omicron BA.1 by examining the breakthrough infections among vaccinees as compared with unvaccinated cases.Our study population comprised all 430 cases during the outbreak of Omicron BA.1 in Tianjin. | Hong Zheng Yunlong Cao Xiaosu Chen Fengmei Wang Ye Hu Weiliang Song Yangyang Chai Qingqing Gu Yansong Shi Yingmei Feng Shuxun Liu Yan Xie Xiaoliang Sunney Xie Wentao Jiang Zhongyang Shen | 2022 | Cell Research2022，32，8： | 12 |
| 2 | Malus-metasurface-assisted polarization multiplexing显示文摘Polarization optics plays a pivotal role in diffractive,refractive,and emerging flat optics,and has been widely employed in contemporary optical industries and daily life.Advanced polarization manipulation leads to robust control of the polarization direction of light.Nevertheless,polarization control has been studied largely independent of the phase or intensity of light.Here,we propose and experimentally validate a Malus-metasurface-assisted paradigm to enable simultaneous and independent control of the intensity and phase properties of light simply by polarization modulation.The orientation degeneracy of the classical Malus’s law implies a new degree of freedom and enables us to establish a one-to-many mapping strategy for designing anisotropic plasmonic nanostructures to engineer the Pancharatnam–Berry phase profile,while keeping the continuous intensity modulation unchanged.The proposed Malus metadevice can thus generate a near-field greyscale pattern,and project an independent far-field holographic image using an ultrathin and single-sized metasurface.This concept opens up distinct dimensions for conventional polarization optics,which allows one to merge the functionality of phase manipulation into an amplitudemanipulation-assisted optical component to form a multifunctional nano-optical device without increasing the complexity of the nanostructures.It can empower advanced applications in information multiplexing and encryption,anti-counterfeiting,dual-channel display for virtual/augmented reality,and many other related fields. | Liangui Deng Juan Deng Zhiqiang Guan Jin Tao Yang Chen Yan Yang Daxiao Zhang Jibo Tang Zhongyang Li Zile Li Shaohua Yu Guoxing Zheng Hongxing Xu Cheng-Wei Qiu Shuang Zhang | 2020 | Light(Science & Applications)2020，9，1： | 7 |
| 3 | Genetic Types and Metallogenic Model for the Polymetallic Copper–Gold Deposits in the Tongling Ore District, Anhui Province, Eastern China显示文摘The Tongling ore district is one of the most economically important ore areas in the Middle–Lower Yangtze River Metallogenic Belt, eastern China. It contains hundreds of polymetallic copper–gold deposits and occurrences. Those deposits are mainly clustered(from west to east) within the Tongguanshan, Shizishan, Xinqiao, Fenghuangshan, and Shatanjiao orefields. Until recently, the majority of these deposits were thought to be skarn-or porphyry–skarn-type deposits; however there have been recent discoveries of numerous vein-type Au, Ag, and Pb-Zn deposits that do not fall into either of these categories. This indicates that there is some uncertainty over this classification. Here, we present the results of several systematic geological studies of representative deposits in the Tongling ore district. From investigation of the ore-controlling structures, lithology of the host rock, mineral assemblages, and the characteristics of the mineralization and alteration within these deposits, three genetic types of deposits(skarn-, porphyry-, and vein-type deposits) have been identified. The spatial and temporal relationships between the orebodies and Yanshanian intrusions combined with the sources of the ore-forming fluids and metals, as well as the geodynamic setting of this ore district, indicate that all three deposit types are genetically related each other and constitute a magmatic–hydrothermal system. This study outlines a model that relates the polymetallic copper–gold porphyry-, skarn-, and vein-type deposits within the Tongling ore district. This model provides a theoretical basis to guide exploration for deep-seated and concealed porphyry-type Cu(–Mo, –Au) deposits as well as shallow vein-type Au, Ag, and Pb–Zn deposits in this area and elsewhere. | FU Zhongyang XU Xiaochun HE Jun FAN Ziliang XIE Qiaoqin DU Jianguo CHEN Fang | 2019 | Acta Geologica Sinica(English Edition)2019，93，1： | 6 |
| 4 | Influence of torrefaction pretreatment on biomass gasification technology显示文摘Torrefaction is a slow pyrolysis process that is carried out in the relatively low temperature range of 220-300°C.The influence of torrefaction as a pretreatment on biomass gasification technology was investigated using a bench-scale torrefaction unit,a bench-scale laminar entrained-flow gasifier,and the analysis techniques TGA-FTIR and low temperature nitrogen adsorption.A series of experiments were performed to examine the characteristics of the torrefaction process,the properties of torrefaction products,and the effects of torrefaction on gas composition,cold gas efficiency and gasification efficiency.The results showed that during the torrefaction process the moisture content of biomass were reduced,and the wood fiber structure of the material was destroyed.This was beneficial to storage,transport and subsequent treatments of biomass in large scale.For solid products,torrefaction increased the energy density,decreased the oxygen/carbon ratio,and created a more complex pore structure.These improved the syngas quality and cold gas efficiency.Combustible gases accounted for about 50% of non-condensable gaseous torrefaction products.Effective use of the torrefaction gases can save energy and improve efficiency.Overall,biomass torrefaction technology has good application prospects in gasification processes. | CHEN Qing ZHOU JinSong LIU BingJun MEI QinFeng LUO ZhongYang | 2011 | Chinese Science Bulletin2011，56，14： | 6 |
| 5 | Spatial calculating analysis model research of land-use change in urban fringe districts显示文摘The spatial calculating analysis model is based on GIS overlay. It compartmental-izes the research district land into three spatial parts: unchanged part,converted part and increased part. By this method we can evaluate the numerical model and dynamic degree model for existing calculating changing speed of land-use. Fur-thermore the paper raises reviving the calculating analysis model of spatial infor-mation in order to predict the dynamic changing level of all sorts of land. More concretely speaking,the model is mainly to know the changing area and changing speed (increased or decreased) of different land classifications from the micro-cosmic angle and to clearly show the spatial distribution and spatio-temporal law for changing urban lands. We discover why the situation has taken place by com-bining social and economic conditions. The result indicates that the calculating analysis model of spatial information can derive more accurate procedure of spatial transference and increase of all kinds of land from the microcosmic angle. By this model and technology,we can make the research of spatio-temporal structure evolution in land-use be more systematical and deeper. The result will benefit the planning management of urban land-use of developed districts in China in the fu-ture. | ZHANG XinChang,PAN Qiong,WANG ZhongYang & CHEN XinXiang Department of Remote Sensing and GIS Engineering,Sun Yat-sen University,Guangzhou 510275,China | 2008 | Science China(Technological Sciences)2008，51，S1： | 5 |
| 6 | The distribution of chlorophyll a in the tropical eastern Indian Ocean in austral summer显示文摘To study the effect of hydrographic factors on the spatial distributions of chlorophyll a (Chl a), an investigation was carried out in the tropical eastern Indian Ocean (80 -100 E along 7 S, and 7 -18 S along 80 E) in December 2010. The fluorescent method was used to obtain total Chl a and size-fractioned Chl a at the 26 stations. The results show that surface Chl a concentration averaged at (0.168 ± 0.095) mg/m 3 s.d. (range: 0.034-0.475 mg/m 3 ), concentrations appeared to be higher in the west for longitudinal variations, and higher in the north for latitudinal variations. Furthermore, the surface Chl a concentration was lower (0.034-0.066 mg/m 3 ) in the region to the south of 16 S. There was a strong subsurface Chl a maximum layer at all stations and the depth of the Chl a maximum increased towards to the east and south along with the respective nitracline. The spatial variation of Chl a was significant: correlation and regression analysis suggests that it was primarily affected by PO 3 4 , N(NO 3 -N+NO 2 -N) and temperature. Size-fractionated Chl a concentration clearly showed that the study area was a typical oligotrophic open ocean, in which picophytoplankton dominated, accounting for approximately 67.8% of total Chl a, followed by nanophytoplankton (24.5%) and microphytoplankton (7.6%). The two larger fractions were sensitive to the limitation of P, while picophytoplankton was primarily affected by temperature. | HONG Lisha WANG Chunsheng ZHOU Yadong CHEN Mianrun LIU Hongbin LIN Zhongyang SONG Xunshu | 2012 | Acta Oceanologica Sinica2012，31，5： | 3 |
| 7 | Integrative analysis of prognostic long non-coding RNAs with copy number variation in bladder cancer显示文摘Copy number variations(CNVs), which can affect the role of long non-coding RNAs(lncRNAs), are important genetic changes seen in some malignant tumors. We analyzed lncRNAs with CNV to explore the relationship between lncRNAs and prognosis in bladder cancer(BLCA). Messenger RNA(mRNA) expression levels, DNA methylation, and DNA copy number data of 408 BLCA patients were subjected to integrative bioinformatics analysis. Cluster analysis was performed to obtain different subtypes and differently expressed lncRNAs and coding genes. Weighted gene co-expression network analysis(WGCNA) was performed to identify the co-expression gene and lncRNA modules. CNV-associated lncRNA data and their influence on cancer prognosis were assessed with Kaplan-Meier survival curve. Multi-omics integration analysis revealed five prognostic lncRNAs with CNV, namely NR2 F1-AS1, LINC01138, THUMPD3-AS1, LOC101928489, and TMEM147-AS1, and a risk-score signature related to overall survival in BLCA was identified. Moreover, validated results in another independent Gene Expression Omnibus(GEO) dataset, GSE31684, were consistent with these results. Kyoto Encyclopedia of Genes and Genomes(KEGG) enrichment analysis revealed that the mitogen-activated protein kinase(MAPK) signaling pathway, focal adhesion pathway, and Janus kinase-signal transducers and activators of transcription(JAK-STAT) signaling pathway were enriched in a high-risk score pattern, suggesting that imbalance in these pathways is closely related to tumor development. We revealed the prognosis-related lncRNAs by analyzing the expression profiles of lncRNAs and CNVs, which can be used as prognostic biomarkers for BLCA. | Wenwen ZHONG Dejuan WANG Bing YAO Xiaoxia CHEN Zhongyang WANG Hu QU Bo MA Lei YE Jianguang QIU | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021，22，8： | 2 |
| 8 | Similar distribution of simple sequence repeats in diverse completed Human lmmunodeficiency Virus Type 1 genomes显示文摘 | Ming Chen Zhongyang Tan Jianhui Jiang Mingfu Li Hongjun Chen and Ruqin Yu | 2009 | Federation of European Biochemical Societies2009，583，： | 1 |
| 9 | Scheduling algorithm for MPEG-2 TS multiplexers in CATV networks显示文摘 | Du Jianghong Xu Zhongyang Chen Hao and Ding Hui | 2000 | IEEE Transactions on Broadcasting2000，46，4： | 1 |
| 10 | F3 peptide-functionalized PEG-PLA nanoparticles co-administrated with tLyp-1 peptide for anti-glioma drug delivery显示文摘 | Quanyin Hu Guangzhi Gu Zhongyang Liu Mengyin Jiang Ting Kang Deyu Miao Yifan Tu Zhiqing Pang Qingxiang Song Lei Yao Huimin Xia Hongzhan Chen Xinguo Jiang Xiaoling Gao Jun Chen | 2013 | Biomaterials2013，，4： | 1 |
| 11 | Catalytic transformations of acids, aldehydes, and phenols in bio-oil to alcohols and esters显示文摘 | Chen Wen Luo Zhongyang Yu Chunjiang | 2014 | Fuel2014，135，： | 1 |
| 12 | Transformer Winding I)eformation Diagn(stie System U- sing Online High Frequency Signal Injection by Capacitive Coupling 显示文摘 | Yao Chenguo Zhao Zhongyang Chen Yn Zhao Xiaozhen Li Zhao- jiong | 2014 | IEEE Transaetion on Dielectrics and Electrical Insulation2014，21，4： | 1 |
| 13 | Variational Inference Based Kernel Dynamic Bayesian Networks for Construction of Prediction Intervals for Industrial Time Series With Incomplete Input显示文摘Prediction intervals(PIs)for industrial time series can provide useful guidance for workers.Given that the failure of industrial sensors may cause the missing point in inputs,the existing kernel dynamic Bayesian networks(KDBN),serving as an effective method for PIs construction,suffer from high computational load using the stochastic algorithm for inference.This study proposes a variational inference method for the KDBN for the purpose of fast inference,which avoids the timeconsuming stochastic sampling.The proposed algorithm contains two stages.The first stage involves the inference of the missing inputs by using a local linearization based variational inference,and based on the computed posterior distributions over the missing inputs the second stage sees a Gaussian approximation for probability over the nodes in future time slices.To verify the effectiveness of the proposed method,a synthetic dataset and a practical dataset of generation flow of blast furnace gas(BFG)are employed with different ratios of missing inputs.The experimental results indicate that the proposed method can provide reliable PIs for the generation flow of BFG and it exhibits shorter computing time than the stochastic based one. | Long Chen Linqing Wang Zhongyang Han Jun Zhao Wei Wang | 2020 | IEEE/CAA Journal of Automatica Sinica2020，7，5： | 1 |
| 14 | Characterization of pyrolytic lignins with different activities obtained from bio-oil显示文摘Pyrolytic lignin, the water-insoluble fraction in bio-oil, often shows a high content and has strong intermolecular interactions with other compounds in bio-oil. In order to obtain pure pyrolytic lignin and facilitate the utilization of aqueous phase obtained from water extraction of bio-oil, methanol–water extraction method was employed to further separate the bio-oil water-insoluble phase in this paper. Different technologies, including Fourier transform infrared spectroscopy, gel permeation chromatography, and nuclear magnetic resonance, were adopted to characterize the structures of pyrolytic lignins with different activities obtained through this method. Both the heating value and the polymerization degree of high-molecular-weight pyrolytic lignin were higher than those of low-molecular-weight pyrolytic lignin. The molecular weight distribution of high-molecular-weight pyrolytic lignin was relatively wider, among which the contents of dimers to pentamers all accounted for 12% –18%,while the low-molecular-weight pyrolytic lignin mainly consisted of trimers(75.38%). The pyrolytic lignins had similar basic structures, both of which contained syringyl and guaiacyl units, whereas the low-molecular-weight pyrolytic lignin had more abundant syringyl units, reactive carbonyl groups and hydroxyl groups. Meanwhile,thermogravimetric study revealed that the final char residue yield of low-molecular-weight pyrolytic lignin was lower than that of high-molecular-weight pyrolytic lignin. | Furong Leng Yurong Wang Junhao Chen Shurong Wang Jinsong Zhou Zhongyang Luo | 2017 | Chinese Journal of Chemical Engineering2017，25，3： | 1 |
| 15 | F3 peptide-functionalized PEG-PLA nanoparticles co-administrated with tLyp-1 peptide for anti-glioma drug delivery显示文摘 | Quanyin Hu Guangzhi Gu Zhongyang Liu Mengyin Jiang Ting Kang Deyu Miao Yifan Tu Zhiqing Pang Qingxiang Song Lei Yao Huimin Xia Hongzhan Chen Xinguo Jiang Xiaoling Gao Jun Chen | 2013 | Biomaterials2013，，4： | 1 |
| 16 | Biomass/Gasification for product gas production: The overall investigation of parametric effects显示文摘 | Chen Guanyi Andries J Luo Zhongyang | 2003 | Energy Conversion and Management2003，44，11： | 1 |
| 17 | Similar distribution of simple sequence repeats in diverse completed Human Immunodeficiency Virus Type 1 genomes显示文摘 | Ming Chen Zhongyang Tan Jianhui Jiang Mingfu Li Hongjun Chen Guoli Shen Ruqin Yu | 2009 | FEBS Letters2009，，17： | 1 |
| 18 | The focal mechanism of the 1966 Xingtai earthquake as inferred from the ground deformation observations 显示文摘 | Chen Yuntai Lin Banghui Lin Zhongyang | 1975 | Acta Geophysica Sinica1975，28，3： | 1 |
| 19 | Scheduling algorithm for MPEG-2TS multiplexers in CATV networks 显示文摘 | DU Jianghong XU Zhongyang CHEN Hao | 2000 | IEEE Transactions on Broadcasting2000，46，4： | 1 |
| 20 | Experimental study on DX pile performance in frozen soils under lateral loading显示文摘Experiments about working mechanism and mechanical characteristics of the DX model pile foundation under lateral dynamic and static loading were conducted by using a model system of the dynamic frozen soil-pile interaction. The horizontal displacement-force relationship of the pile head and bending moment distribution along the body in frozen soils of different temperatures were discussed. According to test results, both the horizontal displacement-force relationship of the DX pile head and bending moment distribution of the DX pile body are smaller than that of equal-diameter piles under same lateral loads. The piles with different plate positions show different displacements and bending moments. This phenomenon is mainly related to the soil temperature and bearing plates locations. Thus, dynamic response analysis of the pile foundation should be taken into account. | XiaoBing Liu LiHong Chen ZhongYang Yu JianXiao Hu Wen Peng | 2013 | Research in Cold and Arid Regions2013，5，5： | 0 |
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