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55篇 您的检索式:作者名="Zhou Xinming"
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1Changes in visibility with PM_(2.5) composition and relative humidity at a background site in the Pearl River Delta region显示文摘In fall–winter, 2007–2013, visibility and light scattering coefficients(b sp) were measured along with PM_(2.5)mass concentrations and chemical compositions at a background site in the Pearl River Delta(PRD) region. The daily average visibility increased significantly(p < 0.01) at a rate of 1.1 km/year, yet its median stabilized at ~13 km. No haze days occurred when the 24-hr mean PM_(2.5)mass concentration was below 75 μg/m^3. By multiple linear regression on the chemical budget of particle scattering coefficient(b sp), we obtained site-specific mass scattering efficiency(MSE) values of 6.5 ± 0.2, 2.6 ± 0.3, 2.4 ± 0.7 and 7.3 ± 1.2 m2/g,respectively, for organic matter(OM), ammonium sulfate(AS), ammonium nitrate(AN) and sea salt(SS). The reconstructed light extinction coefficient(b ext) based on the Interagency Monitoring of Protected Visual Environments(IMPROVE) algorithm with our site-specific MSE revealed that OM, AS, AN, SS and light-absorbing carbon(LAC) on average contributed 45.9% ± 1.6%,25.6% ± 1.2%, 12.0% ± 0.7%, 11.2% ± 0.9% and 5.4% ± 0.3% to light extinction, respectively.Averaged b ext displayed a significant reduction rate of 14.1/Mm·year(p < 0.05); this rate would be 82% higher if it were not counteracted by increasing relative humidity(RH) and hygroscopic growth factor(f(RH)) at rates of 2.5% and 0.16/year-1(p < 0.01), respectively, during the fall–winter, 2007–2013. This growth of RH and f(RH) partly offsets the positive effects of lowered AS in improving visibility, and aggravated the negative effects of increasing AN to impair visibility.Xiaoxin Fu Xinming Wang Qihou Hu Guanghui Li Xiang Ding Yanli Zhang Quanfu He Tengyu Liu Zhou Zhang Qingqing Yu Ruqing Shen Xinhui Bi 2016Journal of Environmental Sciences2016,28,2:18
2TALEN-based generation of a cynomolgus monkey disease model for human microcephaly显示文摘基因在非人类的首领编辑可以为在人探索病原学和遗传上基于的神经病学的混乱的治疗学的策略导致珍贵模型。然而,仔细在人模仿病理学、行为的赤字的神经病学的混乱的一个猴子模型成功地还没被产生了。Microcephalin 1 (MCPH1 ) 在人的大脑,和智力迟钝伴随的 MCPH1 变化原因头小畸型的进化被含有。这里,我们产生了用抄写带 biallelic MCPH1 变化的一只 cynomolgus 猴子(Macaca fascicularis ) 像使活跃之物的受动器核酸酶。猴子概括了大多数在病人观察的重要临床的特征,包括在头圆周,早熟的染色体冷凝作用(PCC ) ,语料库 callosum 的发育不全和上面的手足 spasticity 的显著减小。而且,在变异的真皮的成纤维细胞的 MCPH1 的 overexpression 救了 PCC 症候群。这个猴子模型可以帮助我们阐明在人的头小畸型并且更好的致病的 MCPH1 的角色在首领大脑尺寸的进化理解这蛋白质的功能。Qiong Ke Weiqiang Li Xingqiang Lai Hong Chen Lihua Huang Zhuang Kang Kai Li Jie Ren Xiaofeng Lin Haiqing Zheng Weijun Huang Yunhan Ma Dongdong Xu Zheng Chen Xinming Song Xinyi Lin Min Zhuang Tao Wang Fengfeng Zhuang Jianzhong Xi Frank Fuxiang Mao Huimin Xia Bruce T Lahn Qi Zhou Shihua Yang Andy Peng Xiang 2016Cell Research2016,26,9:13
3A review of fire-extinguishing agent on suppressing lithium-ion batteries fire显示文摘Safety issue of lithium-ion batteries(LIBs)such as fires and explosions is a significant challenge for their large scale applications.Considering the continuously increased battery energy density and wider large-scale battery pack applications,the possibility of LIBs fire significantly increases.Because of the fast burning and the easy re-ignition characteristics of LIBs,achieving an efficient and prompt LIBs fire suppression is critical for minimizing the fire hazards.Different from conventional fire hazards,the LIBs fire shows complicated and comprehensive characteristics,and an effective and suitable fire-extinguishing agent particularly designed for LIBs is highly desirable.Considerable efforts have been devoted to this topic,to the best of our knowledge,a comprehensive review on this regard is still rare.Moreover,in practice,a guidance for the design and selections of a proper fire-extinguishing agent for LIBs is urgently needed.Herein,the special mechanisms and characteristics for LIBs fire and the corresponding design principles for LIBs fire-extinguishing agent were introduced.It is revealed that a fire-extinguishing agent developed for LIBs fire will most likely need a high heat capacity,high wetting,low viscosity and low electrical conductivity.After a comprehensive comparison of these agents in terms of these performances,water-based fire-extinguishing agents show best.Several typical fire-extinguishing agents such as gaseous agents,dry powders,water-based and aerosol fire-extinguishing agents were then introduced,and their fire extinguishment mechanisms were presented.Finally,their effectiveness in suppressing the fire were summarized.Water-based fire-extinguishing agents possess high cooling capacity and excellent anti-reflash performance for the fire.We believe this review could shed light on developing an efficient fire-extinguishing agent particularly designed for LIBs.Shuai Yuan Chongye Chang Shuaishuai Yan Pan Zhou Xinming Qian Mengqi Yuan Kai Liu 2021Journal of Energy Chemistry2021,30,11:13
4Haze insights and mitigation in China: An overview显示文摘The present article provides an overview of the chemical and physical features of haze in China, focusing on the relationship between haze and atmospheric fine particles, and the formation mechanism of haze. It also summarizes several of control technologies and strategies to mitigate the occurrence of haze. The development of instruments and the analysis of measurements of ambient particles and precursor concentrations have provided important information about haze formation. Indeed, the use of new instruments has greatly facilitated current haze research in China. Examples of insightful results include the relationship between fine particles and haze, the chemical compositions and sources of particles, the impacts of the aging process on haze formation, and the application of technologies that control the formation of haze. Based on these results, two relevant issues need to be addressed: understanding the relationship between haze and fine particles and understanding how to control PM2.5.Xuliang Zhuang Yuesi Wang Hong He Jianguo Liu Xinming Wang Tingyu Zhu Maofa Ge Ju Zhou Guiqian Tang Jinzhu Ma 2014Journal of Environmental Sciences2014,26,1:12
5Parameter identification of hysteretic model of rubber-bearing based on sequential nonlinear least-square estimation显示文摘In order to evaluate the nonlinear performance and the possible damage to rubber-bearings (RBs) during their normal operation or under strong earthquakes, a simplified Bouc-Wen model is used to describe the nonlinear hysteretic behavior of RBs in this paper, which has the advantages of being smooth-varying and physically motivated.Further, based on the results from experimental tests performed by using a particular type of RB (GZN110) under different excitation scenarios, including white noise and several earthquakes, a new system identification method, referred to as the sequential nonlinear least-square estimation (SNLSE), is introduced to identify the model parameters.It is shown that the proposed simplified Bouc-Wen model is capable of describing the nonlinear hysteretic behavior of RBs, and that the SNLSE approach is very effective in identifying the model parameters of RBs.Yin Qiang Zhou Li Wang Xinming 2010Earthquake Engineering and Engineering Vibration2010,9,3:9
6Compositions and sources of organic acids in fine particles(PM_(2.5)) over the Pearl River Delta region, south China显示文摘Organic acids as important constituents of organic aerosols not only influence the aerosols' hygroscopic property, but also enhance the formation of new particles and secondary organic aerosols. This study reported organic acids including C14–C32fatty acids, C4–C9dicarboxylic acids and aromatic acids in PM2.5collected during winter 2009 at six typical urban, suburban and rural sites in the Pearl River Delta region. Averaged concentrations of C14–C32fatty acids, aromatic acids and C4– C9 dicarboxylic acids were 157, 72.5 and 50.7 ng/m3, respectively. They totally accounted for 1.7% of measured organic carbon. C20–C32fatty acids mainly deriving from higher plant wax showed the highest concentration at the upwind rural site with more vegetation around, while C14–C18fatty acids were more abundant at urban and suburban sites, and dicarboxylic acids and aromatic acids except 1,4-phthalic acid peaked at the downwind rural site. Succinic and azelaic acid were the most abundant among C4–C9dicarboxylic acids, and 1,2-phthalic and 1,4-phthalic acid were dominant aromatic acids. Dicarboxylic acids and aromatic acids exhibited significant mutual correlations except for 1,4-phthalic acid, which was probably primarily emitted from combustion of solid wastes containing polyethylene terephthalate plastics. Spatial patterns and correlations with typical source tracers suggested that C14–C32fatty acids were mainly primary while dicarboxylic and aromatic acids were largely secondary. Principal component analysis resolved six sources including biomass burning, natural higher plant wax, two mixed anthropogenic and two secondary sources; further multiple linear regression revealed their contributions to individual organic acids. It turned out that more than 70% of C14–C18fatty acids were attributed to anthropogenic sources, about 50%–85% of the C20–C32fatty acids were attributed to natural sources, 80%–95% of dicarboxylic acids and 1,2-phthalic acid were secondary in contrast with that 81% of 1,4-phthalic acid was primary.Xiuying Zhao Xinming Wang Xiang Ding Quanfu He Zhou Zhang Tengyu Liu Xiaoxin Fu Bo Gao Yunpeng Wang Yanli Zhang Xuejiao Deng Dui Wu 2014Journal of Environmental Sciences2014,26,1:6
7Source apportionment of VOCs in a typical medium-sized city in North China Plain and implications on control policy显示文摘Characteristics of atmospheric VOCs(volatile organic compounds) have been extensively studied in megacities in China, however, they are scarcely investigated in medium/smallsized cities in North China Plain(NCP).A comprehensive research on possible sources of VOCs was conducted in a medium-sized city of NCP, from May to September 2019.A total of 143 canister samples of 8 sites in Xuchang city were collected, and 57 VOC species were detected.The average VOC concentrations were 42.6 ± 31.6 μg/m3, with 53.7 ± 31.0 μg/m3 and 32.1 ± 27.8 μg/m^(3), in the morning and afternoon, respectively.Alkenes and aromatics contributed 80% of the total ozone formation potential(OFP).Aromatics accounted for more than 95% of secondary organic aerosol potential(SOAP).VOCs were dominated by the local emission with significant transport from the southeast direction.PMF analysis extracted 6 sources, which were combustion(33.1%), LPG usage(19.3%), vehicular exhaust & fuel evaporation(15.8%), solvent usage(15.2%), industrial(9.11%) and biogenic(7.51%), respectively and they contributed 33.4%, 17.6%, 12.9%, 18.6%, 9.28% and 8.22% to the OFP, respectively.Combustion and LPG usage were the dominant VOC sources;and combustion, solvent usage and LPG usage were the main sources of OFP in Xuchang city, which were different to megacities in China with a high contribution from vehicular exhaust, solvent usage and industry,suggesting specific control strategies on VOCs need to be implemented in medium-sized city such as Xuchang city.Juanjuan Qin Xiaobo Wang Yanrong Yang Yuanyuan Qin Shaoxuan Shi Peihua Xu Rongzhi Chen Xueming Zhou Jihua Tan Xinming Wang 2021Journal of Environmental Sciences2021,33,9:6
8Relationship between P-glycoprotein and CD44 expression in esophageal carcinoma显示文摘Objective: To investigate the relationship between P-glycoprotein (P-gp) and adhesion molecule CD44 expression as well as their clinical significance in esophageal carcinoma. Methods: To examine the expressed level of P-gp and CD44 by flow cytometry (FCM) in the operated samples of 70 cases with esophageal carcinoma and their normal mucosa of esophageal incision, and to evaluate their relationship with clinicopathological factors. Results: Among the 70 cases with esophageal car- cinoma, the expression of P-gp in the 27 cases (38.6%) was negative (positive cells <25%); 11 cases (15.7%) were 25%–40% expression of P-gp positive cells; 14 cases (20%) were 41%–60% expression of P-gp positive cells; 18 cases (25.7%) were the high expression (positive cells >60%) of P-gp. Of the cases with the tumor sizes being more than 4 cm, the expression of CD44 showed a significant difference (P<0.05) in 25 cases with P-gp positive, compared with 19 cases with P-gp negative. Of the cases with high-mild differentiated esophageal carcinoma, the expression of CD44 showed a significant difference (P<0.05) in 22 cases with P-gp positive, compared with 17 cases with P-gp negative. Of the cases with clinical III--IV stage, the expression of CD44 showed a significant difference (P<0.05) in 26 cases with P-gp positive, compared with 10 cases with P-gp negative. Of the cases with lymph node metastasis, the CD44 expression showed a significant difference (P=0.050) in 27 cases with P-gp positive, compared with 11 cases with P-gp negative. Of the cases of the patients’ age being more than 56 years, the expression of CD44 showed a significant difference (P<0.01) in 27 cases with P-gp positive, compared with 12 cases with P-gp negative. When the P-gp and CD44 expression were positive, the clinical II stage and III–IV stage in esophageal carcinoma was showed a significant difference (P<0.05). Conclusion: When the CD44 and P-gp both have the positive high expression, it will be signifi- cantly associated with the esophageal carcinoma progression and metastasis, so both were a positive expression in esophageal carcinoma, it might suggest a poor and unfavorable prognosis result.Shenhua Xu Yutian Ling Chihong Zhu Dan Su Xinming Zhou Xianglin Liu 2006The Chinese-German Journal of Clinical Oncology2006,5,5:5
9Histogram analysis of apparent diffusion coefficient predicts response to radiofrequency ablation in hepatocellular carcinoma显示文摘Objective: The aim of this study was to predict tumor progression in patients with hepatocellular carcinoma(HCC) treated with radiofrequency ablation(RFA) using histogram analysis of apparent diffusion coefficients(ADC).Methods: Breath-hold diffusion weighted imaging(DWI) was performed in 64 patients(33 progressive and 31 stable) with biopsy-proven HCC prior to RFA. All patients had pre-treatment magnetic resonance imaging(MRI)and follow-up computed tomography(CT) or MRI. The ADC values(ADC_(10), ADC_(30_, ADC_(median) and ADC_(max))were obtained from the histogram's 10 th, 30 th, 50 th and 100 th percentiles. The ratios of ADC_(10), ADC_(30_,ADCmedian and ADCmax to the mean non-lesion area-ADC(RADC_(10), RADC_(30_, RADC_(median), and RADC_(max)) were calculated. The two patient groups were compared. Key predictive factors for survival were determined using the univariate and multivariate analysis of the Cox model. The Kaplan-Meier survival analysis was performed, and pairs of survival curves based on the key factors were compared using the log-rank test.Results: The ADC_(30_, ADCmedian, ADCmax, RADC_(30_, RADC_(median), and RADC_(max) were significantly larger in the progressive group than in the stable group(P<0.05). The median progression-free survival(PFS) was 22.9 months for all patients. The mean PFS for the stable and progressive groups were 47.7±1.3 and 9.8±1.3 months,respectively. Univariate analysis indicated that RADC_(10), RADC_(30_, and RADC_(median) were significantly correlated with the PFS [hazard ratio(HR)=31.02, 43.84, and 44.29, respectively, P<0.05 for all]. Multivariate analysis showed that RADCmedian was the only independent predictor of tumor progression(P=0.04). And the cutoff value of RADC_(median) was 0.71.Conclusions: Pre-RFA ADC histogram analysis might serve as a useful biomarker for predicting tumor progression and survival in patients with HCC treated with RFA.Xiaohong Ma Han Ouyang Shuang Wang Meng Wang Chunwu Zhou Xinming Zhao 2019Chinese Journal of Cancer Research2019,31,2:5
10Study on the Relationship between P-glycoprotein and CD44 Expression in Gastric Carcinoma显示文摘客观:在 P-glycoprotein (P-gp ) 和象他们在胃的癌的临床的意义一样的粘附分子 CD44 之间的关系的调查。方法:Toexamine 在有由流动 cytometryand 的胃的癌的 98 种情况中的 P-gp 和 CD44 的表示水平与 clinicopathological 因素评估他们的关系。结果:在 98 胃的癌之中, 40 个盒子(40.8%) 是 P-gp negative (积极房间 < 25%) ;P-gp 积极房间的 14 盒子(14.2%)were25%-40% 表示;17 个盒子(17.3%) 是 P-gp 积极房间的 41%-60% 表示;27 个盒子(27.5%) 是高表示(积极房间 > 60%) 在有胃的癌的所有病人的 P-gp。当肿瘤尺寸是超过 6 厘米时, CD44 积极的 P-gp 显示出有效差量(P < 0.05 ) 在有 P-gp 的 35 种情况中积极,与它相比在 24 情况 withP-gp negative。当肿瘤在低中等的区分的胃的癌时, CD44 的表示显示出有效差量(P < 0.05 ) 在有 P-gp 的 44 种情况中积极,作为与它相比在有 P-gp 的 30 种情况中否定。当病人在临床的Ⅲ - Ⅳ舞台时, CD44 的表示显示出有效差量(P < 0.05 ) 在有 P-gp 的 42 种情况中积极,作为与它相比在有 P-gp 的 30 种情况中否定。什么时候有淋巴节点转移的病人, theirCD44 表示显示出有效差量(P < 0.05 ) 在有 P-gp 的 46 种情况中积极,与它相比在有 P-gp 的 32 种情况中否定。肿瘤 P-gp 什么时候表示了积极,他们的 CD44expression 将是增加。结论:当 CD44 和 P-gp 两个都有积极高表示时,它将显著地与胃的癌前进和转移被联系因此两个是在胃的癌的积极表情,它可能建议差、相反的预后结果。YU Chuanding XU Shenhua LING Yutian ZHU Chihong ZHOU Xinming LIU Xianglin 2006The Chinese-German Journal of Clinical Oncology2006,5,4:3
11A male-ABCD algorithm for hepatocellular carcinoma risk prediction in HBs Ag carriers显示文摘Objective: Hepatocellular carcinoma(HCC) development among hepatitis B surface antigen(HBs Ag) carriers shows gender disparity, influenced by underlying liver diseases that display variations in laboratory tests. We aimed to construct a risk-stratified HCC prediction model for HBs Ag-positive male adults.Methods: HBs Ag-positive males of 35-69 years old(N=6,153) were included from a multi-center populationbased liver cancer screening study. Randomly, three centers were set as training, the other three centers as validation. Within 2 years since initiation, we administrated at least two rounds of HCC screening using Bultrasonography and α-fetoprotein(AFP). We used logistic regression models to determine potential risk factors,built and examined the operating characteristics of a point-based algorithm for HCC risk prediction.Results: With 2 years of follow-up, 302 HCC cases were diagnosed. A male-ABCD algorithm was constructed including participant's age, blood levels of GGT(γ-glutamyl-transpeptidase), counts of platelets, white cells,concentration of DCP(des-γ-carboxy-prothrombin) and AFP, with scores ranging from 0 to 18.3. The area under receiver operating characteristic was 0.91(0.90-0.93), larger than existing models. At 1.5 points of risk score,26.10% of the participants in training cohort and 14.94% in validation cohort were recognized at low risk, with sensitivity of identifying HCC remained 100%. At 2.5 points, 46.51% of the participants in training cohort and 33.68% in validation cohort were recognized at low risk with 99.06% and 97.78% of sensitivity, respectively. At 4.5 points, only 20.86% of participants in training cohort and 23.73% in validation cohort were recognized at high risk,with positive prediction value of 22.85% and 12.35%, respectively.Conclusions: Male-ABCD algorithm identified individual's risk for HCC occurrence within short term for their HCC precision surveillance.Yuting Wang Minjie Wang He Li Kun Chen Hongmei Zeng Xinyu Bi Zheng Zhu Yuchen Jiao Yong Wang Jian Zhu Hui Zhao Xiang Liu Chunyun Dai Chunsun Fan Can Zhao Deyin Guo Hong Zhao Jianguo Zhou Dongmei Wang Zhiyuan Wu Xinming Zhao Wei Cui Xuehong Zhang Jianqiang Cai Wanqing Chen Chunfeng Qu 2021Chinese Journal of Cancer Research2021,33,3:3
12SIMULATION OF ROLLING TEXTURE OF ALUMINUM WITH LATH MODEL显示文摘1INTRODUCTIONItiswelknownthattextureisoneofthemostimportantparameterswhichdescribethepropertiesofmaterials.Thetexturespredict...Chen, Zhiyong Zhang, Xinming Zhou, Zhuoping Li, Saiyi Yang, Yang 1999中国有色金属学会会刊:英文版1999,9,2:3
13Evaluation of CT findings for the differentiation of benign from malignant primary retroperitoneal tumors显示文摘Zhu Zheng Zhao Xinming Zhao Yanfeng Yang Lei Zhao Jing Dai Jingrui Zhou Chunwu 2014Chinese Medical Journal2014,,1:3
14METASTABLE EXTENSION OF SOLID SOLUBILITY OF RARE-EARTH ELEMENTS IN Al显示文摘The splat folis of Al-RE(RE=Y,La,Ce,Pr,Nd,Sm,Eu,Gd,Tb,Dy,Er and Yb)binary alloys of 0.04—0.06 mm thickness were made by are-melting and hammer-anviltechnique,the.cooling rate is in 106 K/s order of magnitude.The metastable extendedsolid solubilities of these RE elements have been evaluated by measurements of the latticespacings of the rapidly solidified(RS)Al-RE alloys,they are 0.4,0.15,0.21,0.21,0.3,0.5,0.1,0.6,0.65,0.7,0.75,0.2 at.-% for above individual RE clements,respectively.Thesecondary phase in RS Al-RE alloys were identified to be Al4RE for alloys containinglight RE and Eu elements and Al3 RE for alloys containing heavy RE and Y elements.Some factors influencing the extension of solid solubility of Al-RE alloy were discussed.NING Yuantao ZHOU Xinming DAI Hong Institute of Precious Metals,Kunming,Yunnan,China 1992Acta Metallurgica Sinica(English Letters)1992,5,11:2
15Effect of pulsatile perfusion during cardiopulmonary bypass in terms of radial artery sphygmogram显示文摘OBJECTIVE: To investigate a quantitative method for using radial artery pulse waveforms to assess the effect of pulsatile flow during cardiopulmonary bypass(CPB).METHODS: A total of 34 adults with heart disease who underwent open-heart surgery between April2010 and January 2011 were randomized into a pulsatile perfusion group(n=17) and a non-pulsatile perfusion group(n=17). Radial arterial pulse waveforms of pulsatile and non-pulsatile perfusion patients were observed and compared before and during CPB.RESULTS: No pulse waveform could be detected at patients' radial artery in both groups when the aorta was cross-clamped. Pulse waveforms could be detected at pulsatile perfusion patients' radial artery, but could not be detected at non-pulsatile perfusion patients' radial artery during CPB. Additionally, patients' pulse waveforms during pulsatile perfusion were lower than those before the operation.CONCLUSION: Our findings indicate that radial artery sphygmogram can be used as a valid indicator to evaluate the effectiveness of pulsatile perfusion during CPB.Zhifeng Zhang Jiatuo Xu Enyuan Zhu Qi Zhang Lu Yu Yongbing Qiu Jianguo Tang Zhaofu Fei Xin Li Liping Tu Chouping Han Ying Liu Zhen Guo Changle Zhou Meiyu Shi Yingxin Qian Yimin Bao Xinming Ji 2014Journal of Traditional Chinese Medicine2014,34,6:2
16Response of coralline algae Porolithon onkodes to elevated seawater temperature and reduced pH显示文摘Coralline algae(CA),a type of primary calcifying producer presented in coastal ecosystems,are considered one of the highly sensitive organisms to marine environmental change.However,experimental studies on coralline algae responses to elevated seawater temperature and reduced pH have documented either contradictory or opposite results.In this study,we analysed the growth and physiological responses of coralline algae Porolithon onkodes to the elevated temperature(30.8°C)and reduced pH(7.8).The aim of this analysis was to observe the direct and combined effects,while elucidating the growth and photosynthesis in this response.It was demonstrated that the algae thallus growth rate and photosynthesis under elevated temperature were depressed by 21.5%and 14.9%respectively.High pCO2 enhanced the growth and photosynthesis of the thallus at ambient temperature,while they were deceased when both temperature and pCO2 were elevated.CA is among the most sensitive organisms to ocean acidification(OA)because of their precipitate high Mg-calcite.We hypothesize that coralline algae could increase their calcification rate in order to counteract the effects of moderate acidification,but offset by the effect of elevated temperature.Accordingly,our results also support the conclusion that global warming(GW)is a stronger threat to algal performance than OA.Our findings are also proposed that coralline algae may be more resilient under OA than GW.Xinming Lei Lei Jiang Yuyang Zhang Guowei Zhou Jiansheng Lian Hui Huang 2020Acta Oceanologica Sinica2020,39,2:2
17Enhanced trimethylamine-containing particles during fog events detected by single particle aerosol mass spectrometry in urban Guangzhou, China显示文摘Guohua Zhang Xinhui Bi Lo Yin Chan Lei Li Xinming Wang Jialiang Feng Guoying Sheng Jiamo Fu Mei Li Zhen Zhou 2012Atmospheric Environment2012,,:2
18Abemaciclib induces apoptosis in cardiomyocytes by activating the Hippo signaling pathway显示文摘Abemaciclib is the newest cyclin-dependent kinase 4/6 inhibitor that has received approval from the US Food and Drug Administration for using in patients with advanced breast cancer. However, its potential adverse effects on cardiomyocytes remain unknown. In this study, we used the cell counting kit-8 assay, western blot analysis, flow cytometry, immunostaining, and quantitative polymerase chain reaction to investigate the role of abemaciclib in inducing apoptosis and in inhibiting the viability and proliferation of AC16 human cardiomyocyte cells. The results revealed that abemaciclib induced apoptosis and inhibited cell proliferation by activating the Hippo signaling pathway. This work demonstrates the molecular basis by which abemaciclib induces cardiac side effects, providing a theoretical basis and effective targets for the treatment of cardiac diseases.Yajie Zhou Yanfei Li Junwei Shen Jue Li Xinming Li 2020Acta Biochimica et Biophysica Sinica2020,52,8:2
19Triple linear-array image geometry model of ZiYuan-3 surveying satellite and its validation显示文摘Xinming Tang Guo Zhang Xiaoyong Zhu Hongbo Pan Yonghua Jiang Ping Zhou Xia Wang 2013International Journal of Image and Data Fusion2013,,1:1
20On reachableity graphs of Petri nets 显示文摘Xinming Ye Jiantao Zhou Xiaoyu Song 2003Computer and Electrical Engineering2003,29,2:1
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