|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Mapping wetland changes in China between 1978 and 2008显示文摘Four wetland maps for all China have been produced,based on Landsat and CBERS-02B remote sensing data between 1978 and 2008 (1978,1990,2000 and 2008).These maps were mainly developed by manual interpretation and validated by substantial field investigation in 2009.Based on these maps,we analyzed the 2008 wetland distribution in China and discussed wetland changes and their drivers over the past 30 years.(i) There were about 324097 km 2 of wetlands in 2008,for which inland marshes or swamps were the most common wetland type (35%),with lakes (26%) second.Most of the wetlands were in Heilongjiang,Inner Mongolia,Qinghai and Tibet,occupying about 55% of the national wetland area.(ii) From 1978 to 2008,China's wetland area continually and significantly decreased,by about 33% based on changes in the wetland map.This was in sharp contrast to the increase in artificial wetlands,which increased by about 122%.Inland marshes accounted for the main loss of total wetlands from 1978 to 2000.From 2000 through 2008,riverine and lacustrine wetlands constituted the main wetland loss.Fortunately however,the rate of wetland loss decreased from 5523 to 831 km 2 /a.(iii) The change ratio of lost natural wetlands (including inland and coastal wetlands) to non-wetlands has decreased slightly over the past 30 years.From 1978 to 1990,nearly all natural wetlands (98%) lost were transformed into non-wetlands.However,the ratio declined to 86% from 1990 to 2000,and to 77% from 2000 to 2008.(iv) All Chinese provinces were divided into three groups according to patterns of wetland changes,which could relate to the driving forces of such changes.Tibet was completely different from other provinces,as it was one representative example in which there was a net wetland increase,because of global warming and decreased human activity since 1990.Increased economic development caused considerable wetland loss in most eastern provinces,and artificial wetlands increased. | NIU ZhenGuo ZHANG HaiYing WANG XianWei YAO WenBo ZHOU DeMin ZHAO KuiYi ZHAO Hui LI NaNa HUANG HuaBing LI CongCong YANG Jun LIU CaiXia LIU Shuang WANG Lin LI Zhan YANG ZhenZhong QIAO Fei ZHENG YaoMin CHEN YanLei SHENG YongWei GAO XiaoHong ZHU WeiHong WANG WenQing WANG Hong WENG YongLing ZHUANG DaFang LIU JiYuan LUO ZhiCai CHENG Xiao GUO ZiQi GONG Peng | 2012 | Chinese Science Bulletin2012，57，22： | 51 |
| 2 | Mortality and Morbidity of Extremely Low Birth Weight Infants in the Mainland of China: A Multi-center Study显示文摘 | Hui-Jia Lin Li-Zhong Du Xiao-Lu Ma Li-Ping Shi Jia-Hua Pan Xiao-Mei Tong Qiu-Ping Li Jian-Guo Zhou Bing Yi Ling Liu Yun-Bing Chen Qiu-Fen Wei Hui-Qing Wu Mei Li Cui-Qing Li Xi-Rong Gao Shi-Wen Xia Wen-Bin Li Chao-Ying Ya Ling He Kun Liang Xiao-Yu Zhou Shu-Ping Han Qin Lyu Yin-Ping Qiu Wen Li Dong-Mei Chen Hong-Ru Lu Xiao-Hong Liu Hong Liu Zhen-Lang Lin Li Liu Jia-Jun Zhu Hong Xiong Shao-Jie Yue Si-Qi Zhuang | 2015 | Chinese Medical Journal2015，，20： | 49 |
| 3 | Construction of a Genome-Wide Mutant Library in Rice Using CRISPR/Cas9显示文摘 | Meng, Xiangbing Yu, Hong Zhang, Yi Zhuang, Fengfeng Song, Xiaoguang Gao, Songsong Gao, Caixia Li, Jiayang | 2017 | Molecular Plant2017，10，9： | 46 |
| 4 | A national report from China Liver Transplant Registry: steroid avoidance after liver transplantation for hepatocellular carcinoma显示文摘Objective:We aimed to evaluate the efficacy and safety of steroid-free immunosuppression after liver transplantation(LT)for hepatocellular carcinoma(HCC).Methods:We retrospectively analyzed HCC recipients without steroids after LT(SF group,n=368)based on the China Liver Transplant Registry(CLTR)database.These recipients were matched 1:2 with patients using steroids(S group,n=736)for the same period after LT for HCC,according to propensity scores.Results:Multivariate analysis indicates that recipients with younger age[odds ratio(OR),1.053;P=0.011],preoperative hepatitis B virus(HBV)DNA≥1,000 copies/mL(OR,2.597;P=0.004)and beyond Milan criteria(OR,4.255;P<0.001)were identified as the risk factors associated with tumor recurrence in steroid avoidance recipients after LT.The patients fulfilling the Milan criteria in the SF group presented higher overall and tumor-free survival rates than those in the S group(P<0.05).Multivariate analysis revealed that recipient beyond Milan criteria was an independent prognostic factor for overall survival(OR,1.690;P<0.001)and tumor-free survival(OR,2.066;P<0.001).The incidences of new-onset diabetes mellitus(21.20% vs.33.29%,P<0.001),new-onset hypertension(10.05%vs.18.61%,P<0.001)and hyperlipidemia(4.08% vs.7.20%,P=0.042)were significantly lower in the SF group.Conclusions:Steroid-free immunosuppression could be safe and feasible for HBV-related HCC patients in LT.Age,HBV DNA level and Milan criteria maybe risk factors associated with tumor recurrence in steroid avoidance recipients.Recipient beyond Milan criteria was an independent prognostic factor and recipient fulfilling Milan criteria can benefit the most from steroid-free immunosuppression. | Qiang Wei Feng Gao Runzhou Zhuang Qi Ling Qinghong Ke Jian Wu Tian Shen Mangli Zhang Min Zhang Xiao Xu Shusen Zheng | 2017 | Chinese Journal of Cancer Research2017，29，5： | 25 |
| 5 | Impacts of LUCC processes on potential land productivity in China in the 1990s显示文摘Using meteorological data and RS dynamic land-use observation data set, the po-tential land productivity that is limited by solar radiation and temperature is estimated and the impacts of recent LUCC processes on it are analyzed in this paper. The results show that the influence of LUCC processes on potential land productivity change has extensive and unbal-anced characteristics. It generally reduces the productivity in South China and increases it in North China, and the overall effect is increasing the total productivity by 26.22 million tons. The farmland reclamation and original farmlands losses are the primary causes that led potential land productivity to change. The reclamation mostly distributed in arable-pasture and arable-forest transitional zones and oasises in northwestern China has made total productivity increase by 83.35 million tons, accounting for 3.50% of the overall output. The losses of original farmlands driven by built-up areas invading and occupying arable land are mostly distributed in the regions which have rapid economic development, e.g. Huang-Huai-Hai plain, Yangtze River delta, Zhu-jiang delta, central part of Gansu, southeast coastal region, southeast of Sichuan Basin and Urumqi-Shihezi. It has led the total productivity to decrease 57.13 million tons, which is 2.40% of the overall output. | LIU Jiyuan XU Xinliang ZHUANG Dafang GAO Zhiqiang | 2005 | Science China Earth Sciences2005，48，8： | 22 |
| 6 | Effects of inhaled nitric oxide in neonatal hypoxemic respiratory failure from a multicenter controlled trial显示文摘背景血氧不足的呼吸失败(HRF ) 是为要求好攻击的呼吸支持的新生的婴儿的最普通的原因之一。吸入的氮的氧化物(iNO ) 在发达国家作为附属物习惯性地被建立了到常规呼吸支持。学习是在资源与 HRF 在出生不满一月的婴儿调查 iNO 的效果的这的目的限制了状况没有或限制了表面活化剂的使用,高频率摆动的通风(HFOV ) 和身体外的膜 oxygenation.Methods A iNO 的功效的非使随机化的、开的、控制学习在 18 个月被进行。来自有 HRF (氧化索引 15 ) 的 28 所医院的合格术语和近期的出生不满一月的婴儿作为 iNO 或控制有希望地被注册进二个组。主要端点与 dosing 在关系被决定并且 iNO,内在的疾病的严厉,复杂并发症和负担预定的氧化改进和死亡。Intention-to-treat 原则为结果评价被采用。( ppm )对在 10 或 20 部分的 iNO 的反应被氧化在控制(在组之间)和比作 93 控制的基线(在内组) .Results 的参考每百万决定,在在 107 个对待的婴儿的 10 ppm 的 iNO 的起始的剂量显著地从第一个小时( P=0.046 )改进了氧化,与部分应答者的更多,非应答者不与随后的 20ppm 改进了氧化( P=0.018 )。在天坚持的这效果 1 和 3,并且而少数与表面活化剂(10% 对 27%) 被对待,导致了相对更低的死亡(11.2% 对 15%) , HFOV (5%) 或在两个的出生后的 corticosteroids (10%) 组织。在 28 天在的出生后的生活的全面结果对待 iNO 不与 perinatal 窒息,内在的疾病,血氧不足的严厉,或复杂并发症有关,但是到 iNO 的早使用。医院停留的费用不在新生的 HRF 在有表面活化剂或 HFOV 的相对有限的使用的两 groups.Conclusions 是显著地不同的,显著地,更多的应答者在在基线水平上在开始的三天内由改进氧化思考了的对待 iNO 的病人被发现。它为对适当预定和 iNO 的长期的结果的评价保证使随机化的、控制试用。 | WANG Yi-fei LIU Cui-qing GAO Xi-rong YANG Chang-yi SHAN Ruo-bing ZHUANG De-yi CHEN Dong-mei NI Li-ming WANG Hua XIA Shi-wen CHEN Chao | 2011 | Chinese Medical Journal2011，，8： | 16 |
| 7 | Bioactive hydrogels for bone regeneration显示文摘Bone self-healing is limited and generally requires external intervention to augment bone repair and regeneration.While traditional methods for repairing bone defects such as autografts,allografts,and xenografts have been widely used,they all have corresponding disadvantages,thus limiting their clinical use.Despite the development of a variety of biomaterials,including metal implants,calcium phosphate cements(CPC),hydroxyapatite,etc.,the desired therapeutic effect is not fully achieved.Currently,polymeric scaffolds,particularly hydrogels,are of interest and their unique configurations and tunable physicochemical properties have been extensively studied.This review will focus on the applications of various cutting-edge bioactive hydrogels systems in bone regeneration,as well as their advantages and limitations.We will examine the composition and defects of the bone,discuss the current biomaterials for bone regeneration,and classify recently developed polymeric materials for hydrogel synthesis.We will also elaborate on the properties of desirable hydrogels as well as the fabrication techniques and different delivery strategies.Finally,the existing challenges,considerations,and the future prospective of hydrogels in bone regeneration will be outlined. | Xin Bai Mingzhu Gao Sahla Syed Jerry Zhuang Xiaoyang Xu Xue-Qing Zhang | 2018 | Bioactive Materials2018，3，4： | 15 |
| 8 | Land-use induced changes in topsoil organic carbon stock of paddy fields using MODIS and TM/ETM analysis:A case study of Wujiang County,China显示文摘Topsoil soil organic carbon (SOC) that plays an important role in mitigating atmospheric carbon dioxide (CO_2) buildup is greatly affected by human activities.To evaluate the influence of land-use changes on SOC stocks in paddy soils,a new algorithm was developed by integrating MODIS (moderate resolution imaging spectral-radiometer) and TM/ETM data for timely monitoring the land-use change in Wujiang County.Thereafter,the land-use class-maps derived from MODIS and TM/ETM analyses were further used to est... | GAO, Jianfeng PAN, Genxing JIANG, Xiaosan PAN, Jianjun ZHUANG, Dafang | 2008 | Journal of Environmental Sciences2008，20，7： | 15 |
| 9 | A review of heavy-duty legged robots显示文摘Heavy-duty legged robots have been regarded as one of the important developments in the field of legged robots because of their high payload-total mass ratio,terrain adaptability,and multitasking.The problems associated with the development and use of heavy-duty legged robots have motivated researchers to conduct many important studies,covering topics related to the mechanical structure,force distribution,control strategy,energy efficiency,etc.Overall,heavy-duty legged robots have three main characteristics:greater body masses,larger body sizes,and higher payload-total mass ratios.Thus,various heavy-duty legged robots and their performances are reviewed here.This review presents the current developments with regard to heavy-duty legged robots.Also,the main characteristics of high-performance heavy-duty legged robots are determined and conclusions are drawn.Furthermore,the current research of key techniques of heavy-duty legged robots,including the mechanical structure,force distribution,control method,and power source,is described.To assess the transportation capacity of heavy-duty legged robots,performance evaluation parameters are proposed.Finally,problems that need further research are addressed. | ZHUANG HongChao GAO HaiBo DENG ZongQuan DING Liang LIU Zhen | 2014 | Science China(Technological Sciences)2014，57，2： | 15 |
| 10 | SHRIMP U-Pb Dating of Zircons of a Dark Eclogite and a Garnet-bearing Gneissic Granitic Rock from Bixiling,Eastern Dabie Area,Anhui Province:Isotope Chronological Evidence of Neoproterozoic UHP Metamorphism显示文摘The paper reports SHRIMP U-Pb zircon data of a dark eclogite and a post-eclogite garnet-bearing gneissic granitic rock from the Bixiling area, Yuexi County, Anhui Province, in the eastern Dabie Mountains. The eclogite, which is metamorphosed basic tuff, contains very scarce zircons in omphacite or garnet, but more zircons in quartz. They usually exhibit a double-layered texture, as shown clearly in cathodoluminescence images. Their inner main parts give a 206Pb/238U age of 757±7 Ma, representing the approximate age of the high-pressure (HP)- ultrahigh-pressure (UHP) metamorphic event during which the eclogite was formed. The outer peripheral parts of the zircons, which have been modified by late-stage fluids, give an age of 223±3 Ma. The granitic rock contains more zircons of anatectic origin found mostly in feldspar and quartz and usually also showing a similar composite texture. The inner main parts of the anatectic zircons with oscillatory zoning give a 206Pb/238U age of 727±15 Ma for the | CHENG Yuqi LIU Dunyi I.S. WILLIAMS JIAN Ping ZHUANG Yuxun GAO Tianshan | 2000 | Acta Geologica Sinica(English Edition)2000，74，4： | 13 |
| 11 | Core-shell Au@MnO2 nanoparticles for enhanced radiotherapy via improving the tumor oxygenation显示文摘在稳固的肿瘤的本地组织缺氧经常导致抵抗到放射疗法(RT ) ,在哪个氧为提高 DNA 损坏的一个必要元素被电离引起放射。此处,我们开发了 gold@manganese 二氧化物(有聚乙烯乙二醇(木钉) 的 Au@MnO 2) 核心壳 nanoparticles 是的涂层在癌症治疗期间改进 RT 功效的一个新奇 radiosensitizing 代理人。在这 Au@MnO 2 nanostructure ,当金核心是著名 RT 时,交往与的 sensitizer X光检查为在 RT 下面杀死的改进癌症生产控告的粒子, MnO 2壳可以触发内长的 H 2在肿瘤微型环境到的 O 2产生氧并且克服 hypoxiaassociated RT 抵抗。是示威了由在 vitro 并且在 vivo 实验, Au@MnO 2-PEG nanoparticles 充当了有效 radiosensitizers 显著地在 RT 期间提高癌症治疗功效。而且, Au@MnO 2-PEG 的明显的副作用都没在老鼠被观察。因此,我们的工作为 hypoxic 肿瘤的提高的 RT 治疗与潜力介绍 radiosensitizer 的一种新类型。 | Xuan Yi Lei Chen Xiaoyan Zhong Roulin Gao Yitao Qian Fan Wu Guosheng Song Zhifang Chai Zhuang Liu Kai Yang | 2016 | Nano Research2016，9，11： | 12 |
| 12 | Liposomes co-loaded with metformin and chlorin e6 modulate tumor hypoxia during enhanced photodynamic therapy显示文摘Though photodynamic therapy (PDT) has been widely used in the non-invasive destruction of solid tumors, the therapeutic efficacy of PDT is often limited by the hypoxic tumor environment. Herein, we report the innovative use of metformin, an oral hypoglycemic agent commonly used in the treatment of type II diabetes, to improve tumor oxygenation, and overcome tumor hypoxia-associated resistance to PDT. In our design, hydrophilic metformin and modified hydrophobic chlorin e6 (HCe6) are co-encapsulated within the inner cavity and outer membrane of liposomes, respectively. Due to the high uptake of liposome nanoparticles by tumors, and the sustained release of metformin, the intravenous administration of metformin (Met)-HCe6-Liposome nanoparticles greatly improves tumor oxygenation in several different tumor models, as revealed by in vivo photoacoustic imaging and ex vivo immunofluorescence staining. Systemic administration of Met-HCe6-Liposomes followed by in vivo PDT achieved significantly improved therapeutic effects compared to that of PDT without metformin. Hence, our study represents a new strategy for the improvement of PDT efficacy through the modulation of tumor oxygenation by clinically approved agents. | Xuejiao Song Liangzhu Feng Chao Liang Min Gao Guosheng Song Zhuang Liu | 2017 | Nano Research2017，10，4： | 12 |
| 13 | Locally advanced undifferentiated carcinoma with osteoclast-like giant cells of the pancreas显示文摘Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas(UCOGCP) is an unusual pancreatic neoplasm that represents < 1% of all pancreatic malignancies. Moreover, the giant cells of UCOGCP morphologically resemble the benign giant cells of bone tumors. Due to the rarity of this tumor type, the histogenesis and biologic behavior of UCOGCP remain controversial. Here, we report a case of UCOGCP that exhibited an invasive growth pattern involving infiltration of the adjacent bowel loop and portal vein,as well as superior mesenteric vein thrombosis. The patient underwent a distal pancreatectomy with splenectomy and partial colectomy, followed by four cycles of gemcitabine chemotherapy. No evidence of recurrence was detected after ten years. In addition to this case, clinical information on other UCOGCP cases reported in the English literature is summarized. | Hong-Qiao Gao Yin-Mo Yang Yan Zhuang Ping Liu | 2015 | World Journal of Gastroenterology2015，21，2： | 12 |
| 14 | Long-and short-chain AHLs affect AOA and AOB microbial community composition and ammonia oxidation rate in activated sludge显示文摘Quorum sensing(QS)regulation of the composition of ammonia-oxidising archaea(AOA)and ammonia-oxidising bacteria(AOB)communities and functions in wastewater treatment was investigated.Specifically,we explored the role of N-acyl-L-homoserine lactones(AHLs)in microbial community dynamics in activated sludge.On average,the specific ammoniaoxidising-rate increased from 1.6 to 2.8 mg NH_4^+-N/g MLSS/hr after treatment with long-chain AHLs for 16 days,and the addition of AHLs to sludge resulted in an increased number of AOA/AOB amoA genes.Significant differences were observed in the AOA communities of control and AHL-treated cultures,but not the AOB community.Furthermore,the dominant functional AOA strains of the Crenarchaeota altered their ecological niche in response to AHL addition.These results provide evidence that AHLs play an important role in mediating AOA/AOB microbial community parameters and demonstrate the potential for application of QS to the regulation of nitrogen compound metabolism in wastewater treatment. | Jie Gao Yu Duan Ying Liu Xuliang Zhuang Yichen Liu Zhihui Bai Wenlin Ma Guoqiang Zhuang | 2019 | Journal of Environmental Sciences2019，31，4： | 11 |
| 15 | Hemodynamic parameters obtained by transthoracic echocardiography and right heart catheterization: a comparative study in patients with pulmonary hypertension显示文摘背景血液动力学的评估为有肺的 hypertention 的病人的管理是关键的。临床医生们经常比较喜欢一个快速、非侵略的方法。这研究试图与肺的 hypertension.Methods A 在病人为血液动力学的参数的大小检验 transthoracic echocardiography 的可行性未来的单个中心的学习在 42 个病人之中被进行,肺的高血压由不同疾病引起了。Transthoracic echocardiography 和正确心的 catheterization 在 24 个小时以内被执行。收缩、心脏舒张、吝啬的压力(PASP, PADP 和 PAMP ) ,心脏的产量(公司) ,和肺的毛状的楔迫使的肺的动脉(PCWP ) 被两个方法测量。线性关联和 Bland-Altman 分析被执行比较好关联在侵略、非侵略的大小之间被发现为的二组血液动力学的 parameters.Results PASP (r=0.96 ) , PADP (r=0.85 ) , PAMP (r=0.88 ) ,公司(r=0.82 ) ,和 PCWP (r=0.81 ) 。Bland-Altman 方法做的进一步的协议分析证明当大差异为 PAMP 和 PCWP.Conclusions 存在时,为 PASP, PADP,和公司的那偏爱和 95% 信心间隔是临床上可接受的由在有肺的高血压的病人的 PASP, PADP,和公司的非侵略的大小与侵略决心相关很好。Transthoracic echocardiography (TTE ) 为估计 PCWP 和 PAMP 是不恰当的。 | TIAN Zhuang LIU Yong-tai FANG Quan NI Chao CHEN Tai-bo FANG Li-gang GAO Peng JIANG Xiu-chun LI Meng-tao ZENG Xiao-feng | 2011 | Chinese Medical Journal2011，，12： | 11 |
| 16 | Enhancement of acellular cartilage matrix scaffold by Wharton’s jelly mesenchymal stem cell-derived exosomes to promote osteochondral regeneration显示文摘Articular cartilage defect repair is a problem that has long plagued clinicians.Although mesenchymal stem cells(MSCs)have the potential to regenerate articular cartilage,they also have many limitations.Recent studies have found that MSC-derived exosomes(MSC-Exos)play an important role in tissue regeneration.The purpose of this study was to verify whether MSC-Exos can enhance the reparative effect of the acellular cartilage extracellular matrix(ACECM)scaffold and to explore the underlying mechanism.The results of in vitro experiments show that human umbilical cord Wharton’s jelly MSC-Exos(hWJMSC-Exos)can promote the migration and proliferation of bone marrow-derived MSCs(BMSCs)and the proliferation of chondrocytes.We also found that hWJMSC-Exos can promote the polarization of macrophages toward the M2 phenotype.The results of a rabbit knee osteochondral defect repair model confirmed that hWJMSC-Exos can enhance the effect of the ACECM scaffold and promote osteochondral regeneration.We demonstrated that hWJMSC-Exos can regulate the microenvironment of the articular cavity using a rat knee joint osteochondral defect model.This effect was mainly manifested in promoting the polarization of macrophages toward the M2 phenotype and inhibiting the inflammatory response,which may be a promoting factor for osteochondral regeneration.In addition,microRNA(miRNA)sequencing confirmed that hWJMSC-Exos contain many miRNAs that can promote the regeneration of hyaline cartilage.We further clarified the role of hWJMSC-Exos in osteochondral regeneration through target gene prediction and pathway enrichment analysis.In summary,this study confirms that hWJMSC-Exos can enhance the effect of the ACECM scaffold and promote osteochondral regeneration. | Shuangpeng Jiang Guangzhao Tian Zhen Yang Xiang Gao Fuxin Wang Juntan Li Zhuang Tian Bo Huang Fu Wei Xinyu Sang Liuqi Shao Jian Zhou Zhenyong Wang Shuyun Liu Xiang Sui Quanyi Guo Weimin Guo Xu Li | 2021 | Bioactive Materials2021，6，9： | 11 |
| 17 | Ultra-small MoS2 nanodots with rapid body clearance for photothermal cancer therapy显示文摘因为这些 nanomaterials 的长期的保留,许多无机的 nanomaterials 的临床的翻译被毒性问题严重地在身体妨碍。在这研究,我们基于极端小的瞬间 2 nanodots 开发了一个 bio-clearable theranostic 代理人,它被一条灵巧的自底向上的途径通过铵 tetrathiomolybdate 的一步舞 solvothermal 分解综合。在由谷胱甘肽(GSH ) 的修正以后,没有聚集,获得的瞬间 2-GSH nanodots 在各种各样的生理的缓冲区展出了 sub-10-nm 水动力学直径。没有出现在 vitro 毒性可估计,如此的瞬间 2-GSH nanodots 与强壮在红外线附近(NIR ) 吸收度能导致癌症房间的显著 photothermal 脱离。在之上静脉内(i.v ) 注射,瞬间 2-GSH nanodots 的有效肿瘤累积被 photoacoustic 成像观察,并且进一步由瞬间的 biodistribution 的分析证实了。尤其是,与有更大的尺寸的常规瞬间 2 nanoflakes 相对照,瞬间 2-GSH nanodots 经由尿显示出有效身体清理,在注射剂量的多数在就七天以内被清除的地方。老鼠上的肿瘤的 Photothermal 脱离然后与瞬间 2-GSH nanodots 被认识到,完成优秀治疗学的功效。这研究与有效肿瘤 homing/treatment 能力,以及快速的身体清理行为介绍极端小的 nanoparticle 的一种新类型,为没有长期的毒性担心的癌症 theranostics 使它有希望。 | Teng Liu Yu Chao Min Gao Chao Liang Qian Chen Guosheng Song Liang Cheng Zhuang Liu | 2016 | Nano Research2016，9，10： | 10 |
| 18 | Oxygen vacancy enhancing mechanism of nitrogen reduction reaction property in Ru/TiO2显示文摘To search the new effective nitrogen reduction reaction(NRR)electrocatalyst is very important for the ammonia-based industry.Herein,we reported the design of a novel NRR electrocatalyst with Ru NPs loaded on oxygen-vacancy TiO2(Ru/TiO2-Vo).Structural characterizations revealed that oxygen vacancy was loaded in the matrix of Ru/TiO2-Vo.Electrocatalytic results indicated that Ru/TiO2-Vo showed good NRR performance(2.11μg h^-1 cm^-2).Contrast tests showed that NRR property of Ru/TiO2-Vo was much better than those of Ru/TiO-12(B)(0.53μg hcm^-2)and Ru/P25(0.42μg h^-1 cm^-2).Furthermore,density functional theory calculation results indicated catalytic mechanism of NRR and rate-determining step(*N2+1/2 H2→*N+*NH)was the potential-determining step with the overpotential requirement of 0.21 V.A combination of electronic structure analysis and catalytic measurement shed light on the synergistic effect of Ru and oxygen vacancy on the NRR performance. | Shan Cheng Yi-Jing Gao Yi-Long Yan Xu Gao Shao-Hua Zhang Gui-Lin Zhuang Sheng-Wei Deng Zhong-Zhe Wei Xing Zhong Jian-Guo Wang | 2019 | Journal of Energy Chemistry2019，28，12： | 10 |
| 19 | Novel mutation and polymorphism of PRSS1 gene in the Chinese patients with hereditary pancreatitis and chronic pancreatitis显示文摘背景:在猫的变化离子的胰蛋白酶原基因(PRSS1 ) 与世袭胰腺炎(HP ) 在病人被检测了。这研究调查了流行 R122H (c.365 G >
A ) , A121T (c.361 G >
A ) 和 D162D (c.488 C >
T ) 在慢性胰炎的普通、非世袭的形式并且在一个 HP 家庭的变化或多型性。方法:DNA 与慢性胰炎从 54 个病人的血样品被准备(35 酒鬼, 17 自发并且 2 世袭) 并且 120 正常控制。PRSS1 基因被聚合酶链反应(PCR ) 放大,他们的产品被定序分析,相关临床的数据也被收集。结果:PRSS1 的新多型性(c.488 C >
T ) 与慢性胰炎在 25 个病人被发现(包括 HP 家庭的一个影响成员) 并且正常控制的六个成员。C/T 遗传型显著地在慢性胰炎被增加(或:16.379, 95% CI:5.7522 - 52.3663 ) , >
T 改变的 c.488 C 的频率在,与 Hardy-Weinberg,平衡,而是它不影响临床的显型。R122H (c.365 G >
A ) 的通常报导的变化没在任何学习题目被检测。c.361 G >
A 在一个 HP 家庭在 2 个影响成员和一个未受影响的搬运人被发现。一个 HP 家庭的影响成员之一同时在 PRSS1 基因有 c.361 G >
A 变化和多型性(c.488 C >
T ) 。病人的临床的价值(C3, C4, CA19-9 和 HbA1c ) 比有慢性胰炎的另外的病人的那些高。有 HP 的二个病人开发了糖尿病,他们的父亲与胰腺的癌症死了。结论:在 PRSS1 基因的新多型性(c.488 C >
T ) 与慢性胰炎被联系,但是当时,它没影响临床的显型在基因的变化显示出的 A121T (c.361 G >
A ) 在有 HP 的病人的重要关联。 | LIU Qi-cai GAO Feng OU Qi-shui ZHUANG Ze-hao LIN Shou-rong YANG Bin CHENG Zu-jian | 2008 | Chinese Medical Journal2008，，2： | 10 |
| 20 | Method for Analyzing Articulated Torques of Heavy-duty Six-legged Robot显示文摘The accuracy of an articulated torque analysis influences the comprehensive performances of heavy-duty multi-legged robots. Currently, the extremal estimation method and some complex methods are employed to calculate the articulated torques, which results in a large safety margin or a large number of calculations. To quickly obtain accurate articulated torques, an analysis method for the articulated torque is presented for an electrically driven heavy-duty six-legged robot. First, the rearmost leg that experiences the maximum normal contact force is confirmed when the robot transits a slope. Based on the ant-type and crab-type tripod gaits, the formulas of classical mechanics and MATLAB software are employed to theoretically analyze the relevant static torques of the joints. With the changes in the joint angles for the abductor joint, hip joint, and knee joint, variable tendency charts and extreme curves are obtained for the static articulated torques. Meanwhile, the maximum static articulated torques and the corresponding poses of the robot are also obtained. According to the poses of the robot under the maximum static articulated torques, ADAMS software is used to carry out a static simulation analysis. Based on the relevant simulation curves of the articulated torques, the maximum static articulated torques are acquired. A comparative analysis of the maximum static articulated torques shows that the theoretical calculation values are higher than the static simulation values, and the maximum error value is approximately 10%. The proposed method lays a foundation for quickly determining accurate articulated torques to develop heavy-duty six-legged robots. | ZHUANG Hongchao GAO Haibo DING Liang LIU Zhen DENG Zongquan | 2013 | Chinese Journal of Mechanical Engineering2013，26，4： | 9 |
您所在的机构暂未开通此部分的功能，请联系管理员