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| 1 | Fast cooperative trajectory optimization and test verification for close-range satellite formation using Finite Fourier Series method显示文摘The process of formation reconfiguration for close-range satellite formation should take into account the risk of collisions between satellites.To this end,this paper presents a method to rapidly generate low-thrust collision-avoidance trajectories in the formation reconfiguration using Finite Fourier Series(FFS).The FFS method can rapidly generate the collision-avoidance threedimensional trajectory.The results obtained by the FFS method are used as an initial guess in the Gauss Pseudospectral Method(GPM)solver to verify the applicability of the results.Compared with the GPM method,the FFS method needs very little computing time to obtain the results with very little difference in performance index.To verify the effectiveness,the proposed method is tested and validated by a formation control testbed.Three satellite simulators in the testbed are used to simulate two-dimensional satellite formation reconfiguration.The simulation and experimental results show that the FFS method can rapidly generate trajectories and effectively reduce the risk of collision between satellites.This fast trajectory generation method has great significance for on-line,constantly satellite formation reconfiguration. | Mingying HUO Zichen FAN Naiming QI Zhiguo SONG Xin SHI | 2020 | Chinese Journal of Aeronautics2020，33，8： | 3 |
| 2 | The complex multi-symplectic scheme for the generalized sinh-Gordon equation显示文摘In this paper,the complex multi-symplectic method and the implementation of the generalized sinhGordon equation are investigated in detail.The multi-symplectic formulations of the generalized sinh-Gordon equation in Hamiltonian space are presented firstly.The complex method is introduced and a complex semi-implicit scheme with several discrete conservation laws(including a multi-symplectic conservation law(CLS),a local energy conservation law(ECL) as well as a local momentum conservation law(MCL)) is constructed to solve the partial differential equations(PDEs) that are derived from the generalized sinh-Gordon equation numerically.The results of the numerical experiments show that the multi-symplectic scheme has excellent long-time numerical behavior and high accuracy. | HU WeiPeng DENG ZiChen HAN SongMei FAN Wei | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，10： | 2 |
| 3 | Generation of offset surface for tool path in NC machining through level set methods显示文摘 | Hongyao Shen Jianzhong Fu Zichen Chen Yongqiang Fan | 2010 | The International Journal of Advanced Manufacturing Technolo gy2010，46，9： | 1 |
| 4 | Aero-optical effects simulation technique for starlight transmission in boundary layer under high-speed conditions显示文摘Aero-optical effects for starlight transmission in the high-speed flow field will reduce the accuracy of the star sensor on an aircraft.Numerical simulations for aero-optical effects usually require plenty of calculations,which cause difficulties when designing a celestial navigation system for a high-speed aircraft.In this study,an Aero-Optical Simulator For Starlight Transmission(AOSST)in the boundary layer is developed.It effectively reduces the computational burden compared to that of the widely used CFD simulation,and it achieves satisfactory accuracy.In this simulator,gas ellipsoids satisfying certain design rules are used to simulate coherent density structures in boundary layers.Design rules for the gas ellipsoids are found from published experimental and high-fidelity CFD simulation results.The generated wavefront distortion by AOSST is anchored with the scale law for aero-optical distortion in the boundary layer by determining some control parameters,which enables the simulator to output reliable results over a wide range of flight states.Four numerical examples are provided to verify the performance of AOSST.The results demonstrate that AOSST is able to simulate the directional dependence of aero-optical distortions in boundary layers,the variation trend of distorted wavefront shapes with Reynolds number,and the grayscale distribution on the disturbed star map. | Bo YANG Zichen FAN He YU | 2020 | Chinese Journal of Aeronautics2020，33，7： | 1 |
| 5 | Bacteriophages in water pollution control:Advantages and limitations显示文摘Wastewater is a breeding ground for many pathogens,which may pose a threat to human health through various water transmission pathways.Therefore,a simple and effective method is urgently required to monitor and treat wastewater.As bacterial viruses,bacteriophages(phages)are the most widely distributed and abundant organisms in the biosphere.Owing to their capacity to specifically infect bacterial hosts,they have recently been used as novel tools in water pollution control.The purpose of this review is to summarize and evaluate the roles of phages in monitoring pathogens,tracking pollution sources,treating pathogenic bacteria,infecting bloom-forming cyanobacteria,and controlling bulking sludge and biofilm pollution in wastewater treatment systems.We also discuss the limitations of phage usage in water pollution control,including phage-mediated horizontal gene transfer,the evolution of bacterial resistance,and phage concentration decrease.This review provides an integrated outlook on the use of phages in water pollution control. | Mengzhi Ji Zichen Liu Kaili Sun Zhongfang Li Xiangyu Fan Qiang Li | 2021 | Frontiers of Environmental Science & Engineering2021，15，5： | 1 |
| 6 | Jupiter system exploration trajectory design: Summary of the winning solution at CTOC10显示文摘This paper presents the methods and results submitted by the winning team from Harbin Institute of Technology of the 10th China Trajectory Optimization Competition(CTOC10).The problem posed by CTOC10 requires exploring the Jupiter system using a combined spacecraft.The exploration mission consists of the detection of Jupiter’s magnetic field and an exploration of the Galilean moons.The mission is completed through three steps:problem analysis,orbital design process,and data processing.The orbital design process is mainly divided into four parts,namely,repeating groundtrack orbit design,gravity-assisted orbit design,initial orbit parameter selection,and local optimization adjustment.The designed orbit is then evaluated using a heuristic optimization algorithm applied during the data processing.Finally,six full-coverage observations of Jupiter’s magnetic field are realized under the constraints of fuel and time.The final index of the submitted result is 357.8067. | Haiyang Zhang Yabo Hu Zichen Fan Jie Lv Huidong Ma Ze Yu Mingying Huo Gang Zhang | 2021 | Astrodynamics2021，5，1： | 1 |
| 7 | Progresses of mycobacteriophage-based Mycobacterium tuberculosis detection显示文摘Tuberculosis(TB)remains a major cause of morbidity and mortality worldwide,particularly in developing countries.A rapid and efficient method for TB diagnosis is indispensable to check the trend of tuberculosis expansion.The emergence of drug-resistant bacteria has increased the challenge of rapid drug resistance tests.Due to its high specificity and sensitivity,bacteriophage-based diagnosis is intensively pursued.In this review,we mainly described mycobacteriophage-based diagnosis in TB detection,especially two prevalent approaches:fluorescent reporter phage and phage amplified biologically assay(PhaB).The rationale of reporter phage is that phage carrying fluorescent genes can infect host bacteria specifically.Phage amplified biological assay based on the principle that phages can infect the live Mycobacterium tuberculosis in the specimen under suitable conditions and produce plaques.Other phage-based diagnostic methods,such as a combination of the amplified biologically assay and nucleic acid amplification or lateral flow assays,are also actively explored.This review will help us improve the understanding of mycobacteriophages in TB detection and better promote the development of the rapid diagnosis of M.tuberculosis. | ZICHEN LIU SIYAO GUO MENGZHI JI KAILI SUN ZHONGFANG LI XIANGYU FAN | 2020 | BIOCELL2020，44，4： | 0 |
| 8 | Targeting LncRNA LLNLR-299G3.1 with antisense oligonucleotide inhibits malignancy of esophageal squamous cell carcinoma cells in vitro and in vivo显示文摘Accumulating evidence has indicated that long non-coding RNAs(lncRNAs)play critical roles in the development and progression of cancers,including esophageal squamous cell carcinoma(ESCC).However,the mechanisms of lncRNAs in ESCC are still incompletely understood and therapeutic attempts for in vivo targeting cancer-associated lncRNA remain a challenge.By RNA-sequencing analysis,we identified that LLNLR-299G3.1 was a novel ESCC-associated lncRNA.LLNLR-299G3.1 was up-regulated in ESCC tissues and cells and promoted ESCC cell proliferation and invasion.Silencing of LLNLR-299G3.1 with ASO(antisense oligonucleotide)resulted in opposite effects.Mechanistically,LLNLR-299G3.1 bound to cancerassociated RNA binding proteins and regulated the expression of cancer-related genes,including OSM,TNFRSF4,HRH3,and SSTR3.ChIRP-seq(chromatin isolation by RNA purification and sequencing)revealed that these genes contained enriched chromatin binding sites for LLNLR-299G3.1.Rescue experiments confirmed that the effects of LLNLR-299G3.1 on ESCC cell proliferation were dependent on interaction with HRH3 and TNFRSF4.Therapeutically,intravenous delivery of placental chondroitin sulfate A binding peptide-coated nanoparticles containing antisense oligonucleotide(pICSA-BP-ANPs)strongly inhibited ESCC tumor growth and significantly improved animal survival in vivo.Overall,our results suggest that LLNLR-299G3.1 promotes ESCC malignancy through regulating gene-chromatin interactions and targeting ESCC by pICSA-BP-ANPs may be an effective strategy for the treatment of lncRNA-associated ESCC. | LI TIAN YONGYI HUANG BAOZHEN ZHANG YI SONG LIN YANG QIANQIAN CHEN ZHENG WANG YILING WANG QIHAN HE WENHAN YANG SHUYONG YU TIANYU LU ZICHEN LIU KAIPING GAO XIUJUN FAN JIAN SONG RIHONG ZHAI | 2023 | Oncology Research2023，31，4： | 0 |
| 9 | High-Precision Colorimetric Sensing by Dynamic Tracking of Solvent Diffusion in Hollow-Sphere Photonic Crystals显示文摘Expensive instruments and complicated data processing are often required to discriminate solvents with similar structures and properties.Colorimetric sensors with high selectivity,low cost,and good portability are highly desirable to simplify such detection tasks.Herein,we report the fabrication of a photonic crystal sensor based on the self-assembled resorcinol formaldehyde(RF)hollow spheres to realize colorimetric sensing of polar solvents,including homologs and isomers based on the saturated diffusion time.The diffusion of solvent molecules through the photonic crystal film exhibits a unique three-step diffusion profile accompanied by a dynamic color change,as determined by the physicochemical properties of the solvent molecules and their interactions with the polymer shells,making it possible to accurately identify the solvent type based on the dynamic reflection spectra or visual perception.With its superior selectivity and sensitivity,this single-component colorimetric sensor represents a straightforward tool for convenient solvent detection and identification. | Qianqian Fu Jianping Ge Chen Chen Zichen Wang Fan Yang Yadong Yin | 2022 | Research2022，，3： | 0 |
| 10 | Symplectic Analysis on Coupling Behaviors of Spatial Fiexible Damping Beam显示文摘Although the complex structure-preserving method presented in our previous studies can be used to investigate the orbit–attitude–vibration coupled dynamic behaviors of the spatial flexible damping beam,the simulation speed still needs to be improved.In this paper,the infinite-dimensional dynamic model describing the orbit–attitude–vibration coupled dynamic problem of the spatial flexible damping beam is pretreated by the method of separation of variables,and the second-level fourth-order symplectic Runge–Kutta scheme is constructed to investigate the coupling dynamic behaviors of the spatial flexible damping beam quickly.Compared with the simulation speed of the complex structure-preserving method,the simulation speed of the symplectic Runge–Kutta method is faster,which benefits from the pretreatment step.The effect of the initial radial velocity on the transverse vibration as well as on the attitude evolution of the spatial flexible damping beam is presented in the numerical examples.From the numerical results about the effect of the initial radial velocity,it can be found that the appearance of the initial radial velocity can decrease the vibration frequency of the spatial beam and shorten the evolution interval for the attitude angle to tend towards a stable value significantly.In addition,the validity of the numerical results reported in this paper is verified by comparing with some numerical results presented in our previous studies. | Weipeng Hu Xiaojian Xi Zhe Zhai Pengfei Cui Fan Zhang Zichen Deng | 2022 | Acta Mechanica Solida Sinica2022，35，4： | 0 |
| 11 | Prophages domesticated by bacteria promote the adaptability of bacterial cells显示文摘Prophages are temperate phages integrated into the host bacterial genome.They play an important role in the adaptation and the pathogenicity of bacteria,especially pathogenic bacteria.In this review,we described the distribution of prophages in different hosts and different environments,and focused on the significance of prophages.At the singlecell level,prophages can help the host adapt to harsh external environments by directly carrying virulence genes,encoding regulatory factors and activating lysogeny.At the population level,prophages can influence the overall evolutionary direction and ecological function of the host bacterial community.This review will help us understand the important role of prophages as unique organisms in individual bacteria and microbial populations. | ZICHEN LIU YUNFENG DENG MENGZHI JI WENQING SUN XIANGYU FAN | 2020 | BIOCELL2020，44，2： | 0 |
| 12 | Eu^(3+)/Tb^(3+)-doped whitlockite nanocrystals:Controllable synthesis,cell imaging,and the degradation process in the bone reconstruction显示文摘Whitlockite(WH,Ca_(18)Mg_(2)(HPO_(4))_(2)(PO_(4))_(12))is an important inorganic phase in human bones and has positive significance for participating in the bone reconstruction process.In this paper,we report different doping strategies to prepare WH and WH-Ln(Eu/Tb)nanocrystals,and have successfully synthesized WH-Ln(Eu/Tb)nanoparticles(NPs)with bright red or green fluorescence based on ions exchange doping by two-step hydrothermal reaction.WH-5%Ln(Eu/Tb)NPs with the best fluorescence properties were successfully applied to live cell imaging,and WH-5%Eu NPs were implanted into the bone defect site in rabbit femoral condyles to visually observe its degradation process.The related results would help us understand WH nanocrystals and further expand their potential applications in tissue engineering and related fields. | Zichen Yang Tianyu Yao Xiaoyan Zheng Junfeng Hui Daidi Fan | 2022 | Nano Research2022，15，2： | 0 |
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