|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Laparoscopic 肝切除术: 当前的角色和限制显示文摘 Laparoscopic liver resection (LLR) for the treatment of benign and malignant liver lesions is often performed at specialized centers. Technological advances, such as laparoscopic ultrasonography and electrosurgical tools, have afforded surgeons simultaneous improvements in surgical technique. The utilization of minimally invasive techniques for liver resection has been reported to reduce operative time, decrease blood loss, and shorten length of hospital stay with equivalent postoperative mortality and morbidity rates compared to open liver resection (OLR). Non-anatomic liver resection and left lateral sectionectomy are now routinely performed laparoscopically at many institutions. Furthermore, major hepatic resections are performed by pure laparoscopy, hand-assisted technique, and the hybrid method. In addition, robotic surgery and single port surgery are revealing early promising results. The consensus recommendation for the treatment of benign liver disease and malignant lesions remains unchanged when considering a laparoscopic approach, except when comorbidities and anatomic limitations of the liver lesion preclude this technique. Disease free and survival rates after LLR for hepatocellular carcinoma and metastatic colon cancer correspond to OLR. Patient selection is a significant factor for these favorable outcomes. The limitations include LLR of superior and posterior liver lesions; however, adjustments in technique may now consider a laparoscopic approach as a viable option. As growing data continue to reveal the feasibility and efficacy of laparoscopic liver surgery, this skill is increasingly being adopted by hepatobiliary surgeons. Although the full scope of laparoscopic liver surgery remains infrequently used by many general surgeons, this technique will become a standard in the treatment of liver diseases as studies continue to show favorable outcomes. | Rouzbeh Mostaedi Zoran Milosevic Ho-Seong Han Vijay P Khatri | 2012 | World Journal of Gastrointestinal Oncology2012，4，8： | 8 |
| 2 | Adenosquamous carcinoma of the pancreas: Molecular characterization of 23 patients along with a literature review显示文摘Adenosquamous carcinoma of the pancreas(ASCP)is a rare entity. Like adenocarcinoma of the pancreas,overall survival is poor. Characteristics of ASCP include central tumor necrosis, along with osteoclasts and hypercalcemia. Various theories exist as to why this histological subtype exists, as normal pancreas tissue has no benign squamous epithelium. Due to the rarity of this disease, limited molecular analysis has been performed, and those reports indicate unique molecular features of ASCP. In this paper, we characterize 23 patients diagnosed with ASCP through molecular profiling using immunohistochemistry staining, fluorescent in situ hybridization, chromogenic in situ hybridization, and gene sequencing, Additionally, we provide a comprehensive literature review of what is known to date of ASCP.Molecular characterization revealed overexpression in MRP1(80%), MGMT(79%), TOP2A(75), RRM1(42%),TOPO1(42%), PTEN(45%), CMET(40%), and C-KIT(10%) among others. One hundred percent of samples tested were positive for KRAS mutations. This analysis shows heretofore unsuspected leads to be considered for treatments of this rare type of exocrine pancreas cancer. Molecular profiling may be appropriate to provide maximum information regarding the patient's tumor. Further work should be pursued to better characterize this disease. | Erkut Borazanci Sherri Z Millis Ron Korn Haiyong Han Clifford J Whatcott Zoran Gatalica Michael T Barrett Derek Cridebring Daniel D Von Hoff | 2015 | World Journal of Gastrointestinal Oncology2015，7，9： | 6 |
| 3 | 三维推挽式顺变柱体干涉型加速度传感系统显示文摘应用单质量块推挽式顺变柱体和迈克尔逊干涉仪双光路检测进行三维加速度传感器设计;采用DSP和Cygnal51双核设计技术,实现实时信号采集、光相位调制、加速度信号解调等;嵌入TCP/IP协议实现Internet高速网络接口,从而构成实用型实时加速度传感器系统。传感器灵敏度为1.94×103rad/g,交叉灵敏度接近于零。实际测量时系统可以实时、线性地跟踪到加速度信号,三个分量有较好的一致性。 | 王金海 陈才和 Zoran Salcic 丁桂兰 唐东林 | 2006 | 光电工程2006，33，6： | 5 |
| 4 | Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia显示文摘Natural killer(NK)cells are innate cytotoxic lymphoid cells(ILCs)involved in the killing of infected and tumor cells.Among human and mouse NK cells from the spleen and blood,we previously identified by single-cell RNA sequencing(scRNAseq)two similar major subsets,NK1 and NK2.Using the same technology,we report here the identification,by single-cell RNA sequencing(scRNAseq),of three NK cell subpopulations in human bone marrow.Pseudotime analysis identified a subset of resident CD56^(bright) NK cells,NK0 cells,as the precursor of both circulating CD56dim NK1-like NK cells and CD56^(bright) NK2-like NK cells in human bone marrow and spleen under physiological conditions.Transcriptomic profiles of bone marrow NK cells from patients with acute myeloid leukemia(AML)exhibited stress-induced repression of NK cell effector functions,highlighting the profound impact of this disease on NK cell heterogeneity.Bone marrow NK cells from AML patients exhibited reduced levels of CD160,but the CD160high group had a significantly higher survival rate. | Adeline Crinier Pierre-Yves Dumas Bertrand Escalière Christelle Piperoglou Laurine Gil Arnaud Villacreces Frédéric Vély Zoran Ivanovic Pierre Milpied Émilie Narni-Mancinelli Éric Vivier | 2021 | Cellular & Molecular Immunology2021，18，5： | 5 |
| 5 | Monoclonal immunoscintigraphy for detection of metastasis and recurrence of colorectal cancer显示文摘AIM:To assess the clinical role of monoclonal immunoscintigraphy for the detection of metastasis and recurrence of colorectal cancer.METHODS:Monoclonal immunoscintigraphy was performed in patients operated on for colorectal adenocar-cinoma suspected of local recurrence and metastatic disease.The results were compared with conventional diagnostics.RESULTS:Immunoscintigraphic investigation was done in 53 patients.Tumor recurrence occurred in 38 patients,and was confirmed by other diagnostic modalities in 35.In 15 patients,immunoscintigraphic findings were negative,and confirmed in 14 with other diagnostic methods.Comparative analysis confirmed good correlation of immunoscintigraphic findings and the results of conventional diagnostics and the level of tumor marker carcinoembryonic antigen.Statistical analysis of parameters of radiopharmaceutical groups imacis,indimacis and oncoscint presented homogenous characteristics all of three radiopharmaceuticals.The analysis of immunoscintigraphic target focus was clearly improved using tomography.CONCLUSION:Immunoscintigraphy is highly specific and has a good predictive value in local recurrence of colorectal cancer. | Vera Artiko Ana Koljevic Markovi Dragana obi-aranovi Milorad Petrovi Andrija Anti Mirjana Stojkovi Marinko Zuvela Djordjije aranovi Milica Stojkovi Neboja Radovanovi Danijel Galun Aleksandar Milovanovi Jovica Milovanovi Anica Bobi-Radovanovi Zoran Krivokapic Vladimir Obradovi | 2011 | World Journal of Gastroenterology2011，17，19： | 4 |
| 6 | Four-dimensional flow magnetic resonance imaging incirrhosis显示文摘Since its introduction in the 1970’s,magnetic resonance imaging(MRI)has become a standard imaging modality.With its broad and standardized application,it is firmly established in the clinical routine and an essential element in cardiovascular and abdominal imaging.In addition to sonography and computer tomography,MRI is a valuable tool for diagnosing cardiovascular and abdominal diseases,for determining disease severity,and for assessing therapeutic success.MRI techniques have improved over the last few decades,revealing not just morphologic information,but functional information about perfusion,diffusion and hemodynamics as well.Four-dimensional(4D)flow MRI,a time-resolved phase contrast-MRI with three-dimensional(3D)anatomic coverage and velocity encoding along all three flow directions has been used to comprehensively assess complex cardiovascular hemodynamics in multiple regions of the body.The technique enables visualization of 3D blood flow patterns and retrospective quantification of blood flow parameters in a region of interest.Over the last few years,4D flow MRI has been increasingly performed in the abdominal region.By applying different acceleration techniques,taking 4D flow MRI measurements has dropped to a reasonable scanning time of 8 to 12 min.These new developments have encouraged a growing number of patient studies in the literature validating the technique’s potential for enhanced evaluation of blood flow parameters within the liver’s complex vascular system.The purpose of this review article is to broaden our understanding of 4D flow MRI for the assessment of liver hemodynamics by providing insights into acquisition,data analysis,visualization and quantification.Furthermore,in this article we highlight its development,focussing on the clinical application of the technique. | Zoran Stankovic | 2016 | World Journal of Gastroenterology2016，22，1： | 4 |
| 7 | Pyrite Formation in Organic-rich Clay, Calcitic and Coal-Forming Environments显示文摘在与连续褐煤层轮流出现的混合沉积(在泥土,沙岩或页岩的煤碎片) 的一个中新世的淡水序列的黄铁矿形成过程的早 dlagenetic 特征被调查。基于丰富的矿物质,下列主要沉积环境被区分:illite-montmorillonitic (I-M ) , calcitic (Ct ) 和形成煤的环境(CL ) 。为这些 hydrogeochemically 不同的环境,黄铁矿形成上的限制因子的效果处理(硫酸盐和 Fe 的可获得性,有机物的数量和器官的硫的参予) 被相关分析估计。在在特别环境的这些限制因子的效果的重要差别被观察。这些差别被解释在报道进行不同氧化活动, Fe 复杂并且环境和许多吸着的氢指数的腐殖的物质独立的表面建筑群形成性质结盟活跃粘土矿物。有一个相对低的氢指数并且包含黄铁矿先锋上的腐殖的物质(H ) 的氧化活动是的粘土矿物(I-M-and CL 环境) 的 Inenvironments 极大地阻止了黄铁矿形成不管多么作为复杂形成的后果取决于反应 Fe 可获得性。在矛盾在有一个相对高的氢指数的环境,因为它是 calcitic, H 的氧化活动极大地被提高,因此氧化黄铁矿的硫先锋。有机物的氧化度可能也是 humicelectron 领受人的不同活动的后果。 | Gordana DEVI Petar PFENDT Branimir JOVANIEVI Zoran POPOVIC | 2006 | Acta Geologica Sinica(English Edition)2006，80，4： | 4 |
| 8 | Young Genes out of the Male: An Insight from Evolutionary Age Analysis of the Pollen Transcriptome显示文摘 | Xiao Cui Yang Lv Miaolin Chen Zoran Nikoloski David Twell Dabing Zhang | 2015 | Molecular Plant2015，8，6： | 4 |
| 9 | Hematopoietic stem cells in research and clinical applications:The“CD34 issue”显示文摘In this paper,experimental findings concerning the kinetics of hematopoietic reconstitution are compared to corresponding clinical data.Although not clearly apparent,the transplantation practice seems to confirm the basic proposals of experimental hematology concerning hematopoietic reconstitution resulting from successive waves of repopulation stemming from different subpopulations of progenitor and stem cells.One of the 'f irst rate' parameters in clinical transplantations in hematology;i.e.the CD34+ positive cell dose,has been discussed with respect to the functional heterogeneity and variability of cell populations endowed by expression of CD34.This parameter is useful only if the relative proportion of stem and progenitor cells in the CD34+ cell population is more or less maintained in a series of patients or donors.This proportion could vary with respect to the source,pathology,treatment,processing procedure,the graft ex vivo treatment and so on.Therefore,a universal dose of CD34+ cells cannot be def ined.In addition,to avoid further confusion,the CD34+ cells should not be named 'stem cells' or 'progenitor cells' since these denominations only concern functionally characterized cell entities. | Zoran Ivanovic | 2010 | World Journal of Stem Cells2010，2，2： | 3 |
| 10 | 微藻油脂制备生物基多元醇理化性能分析与结构表征显示文摘为了实现有效高值利用非食用、不占耕地的绿色可再生油脂资源,该研究以微藻油脂为原料,采用环氧化-开环法和氢甲酰化-加氢还原法制备了2种生物基多元醇,通过主要理化指标碘值、酸值、环氧基含量、羟值的测定,重要理论理化指标理论双键含量、理论环氧基含量、理论羟值、转化率和选择性的计算,结合气质联用、凝胶渗透色谱、红外光谱、核磁共振等仪器分析手段,对原料和产物的理化性能和结构进行分析与表征。结果表明,微藻油脂的主要脂肪酸是油酸,质量分数为91.10%,碘值为88.46 g/100 g,理论双键含量0.34 mol/100 g,环氧-开环法得到的多元醇碘值降至0.62 g/100 g,羟值为150.35 mg/g,原料转化率和目标产物选择性分别为99.30%和86.74%,结构中引入仲羟基,通过及时除去环氧反应过程中生成的水、开环反应选择适宜的醇用量可提升产品质量。氢甲酰化-加氢还原法得到的多元醇碘值降至2.12 g/100 g,羟值为166.29 mg/g,原料转化率和目标产物选择性分别为97.60%和95.83%,结构中引入伯羟基,该法为非均相反应,催化剂过滤可除,副反应少,溶剂廉价可回收,产品易分离且质量容易控制。2种方法的原料利用率都很高,目标产物选择性好,产品性能可通过简单易行的理化指标测定和理论计算方法进行有效评价,并可利用仪器分析手段快速监测反应进程、保证产品质量、查找质量问题、拓宽应用范围,具有很好的经济性和工业应用前景,研究结果为油脂为原料的生物基多元醇深入研究和工业应用提供了科学可靠的数据基础和技术支持。 | 杨晓琴 喻艳华 谢东 Petrovic Zoran S 洪健 万显美 | 2020 | 农业工程学报2020，36，7： | 3 |
| 11 | Mapping theArabidopsis Metabolic Landscape by Untargeted Metabolomics at Different Environmental Conditions显示文摘新陈代谢的染色体宽的协会研究(mGWAS ) ,因此,代谢物层次被认为是特点,帮助能解开新陈代谢的网络的基因基础。309 Arabidopsis 就职的一个总数在二个独立环境条件(控制和应力) 下面被种并且使遭到到介绍的 untargeted LC-MS-based metabolomic;获得的吸水的代谢物的层次在 GWAS 被使用。我们为超过 3000 半极的代谢物的 two-condition-based GWAS 导致了 123 高度解决的代谢物的察觉量的特点 loci ?(p 1.0E-08 ) 。有趣地,不同地,从在 Arabidopsis 主要代谢物,趋于被很多小效果的 loci 控制,的自然变化,我们在发现几个学生大效果的 loci 控制第二等的代谢物的变化的小效果的 loci 的一个广阔数字。two-condition-based GWAS 被集成用一个时间功课压力实验与导出网络的代谢物抄本关联跟随。通过这条综合途径,我们选择了在结构的基因和代谢物之间的 70 个关键候选人协会,并且试验性地验证了八个新奇协会,他们中的二个在二环境的出现微分基因规定学习了。我们表明联合有 time-course-derived 网络的基于 metabolomics 的 GWAS 两个都为识别代谢物基因协会在不同不能生活的环境下面执行了的大规模 untargeted 的力量,提供进 Arabidopsis 的新陈代谢的风景的新奇全球卓见。 | Si Wu Takayuki Tohge Alvaro Cuadros-lnostroza Hao Tong Hezi Tenenboim Rik Kooke Michael Meret Joost B. Keurentjes Zoran Nikoloski Alisdair R. Fernie Lothar Willmitzer Yariv Brotman | 2018 | Molecular Plant2018，11，1： | 3 |
| 12 | Influence of 1-Methylcyclopropene (1-MCP) on Postharvest Storage Quality in Green Bell Pepper Fruit显示文摘 | Zoran S. Ili? Radmila Trajkovi? Yaacov Perzelan Sharon Alkalai-Tuvia Elazar Fallik | 2012 | Food and Bioprocess Technology2012，，7： | 2 |
| 13 | 下一代无线终端的体系结构显示文摘 | Zoran Zvonar | 2006 | 电子产品世界2006，13，09S： | 2 |
| 14 | Comparison of light absorption and oxidative potential of biodiesel/diesel and chemicals/diesel blends soot particles显示文摘Soot particles,mainly coming from fuel combustion,affect climate forcing through absorbing light and also result in adverse human health outcomes.Though biodiesel or additives blending with diesel was considered environmentally friendly,the understanding on absorbing and oxidative capacity of soot emitted from them are still unclear.The watersoluble organic carbon(WSOC)content,surface chemical structure,light absorption and oxidative potential(OPDTT)of soot from biodiesel/diesel and chemicals/diesel blends were investigated utilizing total organic carbon analyzer,X-ray photoelectron spectrometer,ultraviolet–visible spectrophotometry and dithiothreitol(DTT)assay.The differences and correlations between soot properties were statistically analyzed.Chemicals/diesel blends soot owned significantly higher WSOC content,ratio of mass absorbing efficiency(MAE)in250 and 365 nm(E2/E3),OPDTT,and higher surface carbonyl content.Coconut biodiesel/diesel blends soot contained evidently higher aromatic carbon–oxygen single bond(ArC–O)content,and higher MAE365.The individual comparison of biodiesel/diesel blends showed20%coconut biodiesel blend owned the lowest WSOC,E2/E3 and OPDTT,while highest ArC–O and MAE365,representing strongest absorbing properties.Association analysis showed OPDTTwas significantly positively correlated with WSOC.Further,the evident negative correlation between MAE365 and OPDTT was observed.Our results showed coconut biodiesel/diesel blends soot induced lower levels of oxidative potential,whereas absorption of light was higher,which have far reaching consequences on climate forcing.Therefore,it is important to evaluate the balance point between light-absorbing properties and oxidative potential,under the wide use of biodiesel. | Yu Kuang Yi Guo Jiaqi Chai Jing Shang Jiali Zhu Svetlana Stevanovic Zoran Ristovski | 2020 | Journal of Environmental Sciences2020，32，1： | 2 |
| 15 | Efficient adaptive density estimation per image pixel for the task of background subtraction显示文摘 | Zoran Zivkovic Ferdinand van der Heijden | 2005 | Pattern Recognition Letters2005，，7： | 2 |
| 16 | Tracking Groups of People显示文摘 | Stephen J. McKenna Sumer Jabri Zoran Duric Azriel Rosenfeld Harry Wechsler | 2000 | Computer Vision and Image Understanding2000，，1： | 2 |
| 17 | Adenosquamous carcinoma arising within a retrorectal tailgut cyst: Report of a case显示文摘Retrorectal, developmental tail gut cysts, include dermoid cysts, rectal duplication cysts and retrorectal cyst-hamartomas. Retrorectal cyst-hamartomas (RCH) are derived from remnants of the tail gut, the most caudal part of the embryonic hind gut, which normally involutes by the 8th wk of embryonic development (3-8 mm stage). They have specific radiological and histopathological features that distinguish them from other similar formations (dermoid cysts, enteric duplication cysts and teratomas). We report a patient with adenosquamous carcinoma arising within RCH, who underwent complete resection of the cyst through anterior laparotomy, and reached complete (recurrencefree for 14 mo, so far) functional recovery. The cyst was incidentally discovered during hysterectomy 12 years ago.Diagnostic, therapeutic and histopathological aspects of this rare case are discussed. The mentioned period between diagnosis and surgical treatment suggests that RCH, given enough time, can develop malignant degeneration, and should be resected at the time of diagnosis. | Zoran Krivokapic Ivan Dimitrijevic Goran Barisic Velimir Markovic Miodrag Krstic | 2005 | World Journal of Gastroenterology2005，11，39： | 2 |
| 18 | Analysis of Short-Term Metabolic Alterations in Arabidopsis Following Changes in the Prevailing Environmental Conditions显示文摘尽管我们有关到相反的 growthconditions 的新陈代谢的调整的重要性的知识的可观的增加最近被提供了,相对,很少对响应 fluctuationin 发生的调整被知道环境因素。评估发生在这样改变环境条件下面的新陈代谢的调整增加我们在是影响 bysuch 的主要小径之间的串音的当前的理解的好机会调节的 offersa。到这个目的,在正常条件下面成长的植物被转移到不同的光,温度 conditionswhich 被期望影响(在另外的过程之中) 光合作用和 photorespiration 和 characterizedat 的率跟随这转变的生理、分子、新陈代谢的层次。我们的结果揭示了类似的行为 inresponse 到处理并且与植物 metabolism.They 的小径进一步加亮的专业一起暗示 photorespiration 的一个紧密的连接这些小径的规定的多数没在叶新陈代谢是的 transcriptionbut 的水平被调停,这相当预先平衡在这些输入 parameters.Key 适应变化词: | Alexandra Florian Zoran Nikoloski Ronan Sulpice Stefan Timm Wagner L. Araujo Takayuki Tohge Hermann Bauwe Alisdair R. Fernie | 2014 | Molecular Plant2014，7，5： | 2 |
| 19 | Brain–computer interfaces for human gait restoration显示文摘In this review article, we present more than a decade of our work on the development of brain–computer interface (BCI)systems for the restoration of walking following neurological injuries such as spinal cord injury (SCI) or stroke. Most ofthis work has been in the domain of non-invasive electroencephalogram-based BCIs, including interfacing our system witha virtual reality environment and physical prostheses. Real-time online tests are presented to demonstrate the ability ofable-bodied subjects as well as those with SCI to purposefully operate our BCI system. Extensions of this work are alsopresented and include the development of a portable low-cost BCI suitable for at-home use, our ongoing eforts to develop afully implantable BCI for the restoration of walking and leg sensation after SCI, and our novel BCI-based therapy for strokerehabilitation. | Zoran Nenadic | 2021 | Control Theory and Technology2021，19，4： | 2 |
| 20 | 干涉型集成光学加速度计信号处理及SOPC设计显示文摘介绍了集成光学芯片、光纤质量块简谐振子和可编程片上系统(SOPC)混合集成光学加速度计的设计方法。采用迈克尔逊干涉方法实现加速度信号光相位调制,综合交流相位跟踪零差补偿技术(PTAC)和合成外差信号解调技术(SHSD)补偿误差并解调出加速度信号,应用SOPC技术设计和实现数字信号处理(DSP)系统,同时实现DSP和智能化数据传输接口并行工作,使系统实时、线性地跟踪到加速度信号。系统设计灵敏度达4.8902V/g。实际测量灵敏度达4.62V/g,工作频带10~1066Hz。 | 王金海 陈才和 Zoran Salcic 郭维廉 张诚 | 2006 | 固体电子学研究与进展2006，26，3： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员