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| 1 | Tectonic subsidence of the Zhu I Sub-basin in the Pearl River Mouth Basin, northern South China Sea显示文摘 | Xiaoyin TANG Shuchun YANG Junzhang ZHU Zulie LONG Guangzheng JIANG Shaopeng HUANG Shengbiao HU | 2017 | Frontiers of Structural and Civil Engineering2017，11，4： | 5 |
| 2 | Preparation and characterization of magnetic P (St-co-MAA-co-AM) microspheres 显示文摘 | Liu Zuli Yang Xiongbo Yao Kailun | 2006 | J Magn Magn Mater2006，302，： | 1 |
| 3 | Bone marrow metastasis from advanced gastric cancer complicated with disseminated intravascular coagulation:a highly aggressive but manageable disease subtype显示文摘Dear Editor,Gastric cancer(GC)is the fifth most commonly diagnosed cancer and the fourth cause of cancer-related death worldwide[1,2].It has a greater prevalence in Eastern Asia,compared to other parts of the world,whereby more than two-thirds of the cases are diagnosed as advanced gastric cancer(AGC)[3].Disseminated intravascular coagulation(DIC)is a clinicopathologic syndrome characterized by laboratory evidence of platelets and clotting factors consumption,and proteolytic degradation. | Xiaohui Zhai Caiqin Wang Shanshan Li Taiyuan Cao Ge Du Yan Zhang Dianke Chen Xinjuan Fan Yan Huang Ping Hu Jian Zheng Zuli Yang Lei Lian Junsheng Peng Ping Lan Jian Xiao | 2022 | Cancer Communications2022，42，4： | 0 |
| 4 | 广州市天河区结直肠癌筛查:基于粪便免疫化学检测和危险因素初步筛选出需要行结肠镜检查者显示文摘目的:探讨联合粪便免疫化学检测(FIT)和高危因素问卷调查(HRFQ)初筛出需行结肠镜检查者的结直肠癌(CRC)筛查方案应用于中国的可行性。方法:2015-2016年间,我们对中国广州市天河区45岁以上居民进行了一项CRC筛查项目。所有筛查对象均接受FIT检测和HRFQ调查,作为初筛。对于FIT阳性和/或HRFQ调查结果考虑存在高危风险的受检者,我们推荐其行进一步结肠镜检查。结果:共计10074名居民纳入CRC筛查项目,其中17.5%的受检者FIT阳性,19.4%经HRFQ调查被认为具有高危风险。经推荐,有773名受检者接受了进一步的结肠镜检查。该筛查方案对非腺瘤性息肉、低危腺瘤、高危腺瘤和CRC的总体阳性预测值分别为4.9%、11.4%、15.9%和1.6%。其中,FIT阳性结果对上述四种病变的阳性预测值分别为5.2%、15.9%、22.5%和2.5%,HRFQ阳性结果分别为4.1%、10.2%、14.3%和1.4%,FIT和HRFQ均为阳性结果的阳性预测值分别为4.5%、16.4%、23.7%和2.8%。结论:我们的两步法CRC筛查策略(FIT和HRFQ阳性者行进一步结肠镜检查)可有效发现早期CRC。鉴于对CRC和腺瘤较的高检出率和阳性预测值,该筛查方案可继续用于我们这项大规模CRC筛查项目的后续研究。 | Yi Liao Senmao Li Chunyu Chen Xuan He Feng Lin Jianping Wang Zuli Yang Ping Lan | 2018 | Gastroenterology Report2018，6，2： | 0 |
| 5 | The cross-talk between methylation and phosphorylation in lymphoid-specific helicase drives cancer stem-like properties显示文摘Posttranslational modifications(PTMs)of proteins,including chromatin modifiers,play crucial roles in the dynamic alteration of various protein properties and functions including stem-cell properties.However,the roles of Lymphoid-specific helicase(LSH),a DNA methylation modifier,in modulating stem-like properties in cancer are still not clearly clarified.Therefore,exploring PTMs modulation of LSH activity will be of great significance to further understand the function and activity of LSH.Here,we demonstrate that LSH is capable to undergo PTMs,including methylation and phosphorylation.The arginine methyltransferase PRMT5 can methylate LSH at R309 residue,meanwhile,LSH could as well be phosphorylated by MAPK1 kinase at S503 residue.We further show that the accumulation of phosphorylation of LSH at S503 site exhibits downregulation of LSH methylation at R309 residue,which eventually promoting stem-like properties in lung cancer.Whereas,phosphorylation-deficient LSH S503A mutant promotes the accumulation of LSH methylation at R309 residue and attenuates stem-like properties,indicating the critical roles of LSH PTMs in modulating stem-like properties.Thus,our study highlights the importance of the crosstalk between LSH PTMs in determining its activity and function in lung cancer stem-cell maintenance. | Na Liu Rui Yang Ying Shi Ling Chen Yating Liu Zuli Wang Shouping Liu Lianlian Ouyang Haiyan Wang Weiwei Lai Chao Mao Min Wang Yan Cheng Shuang Liu Xiang Wang Hu Zhou Ya Cao Desheng Xiao Yongguang Tao | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
| 6 | La-doped Copper Nitride Films Prepared by Reactive Magnetron Sputtering显示文摘Copper nitride film (Cu3N) and La-doped copper nitride films (LaxCu3N) were prepared on glass substrates by reactive magnetron sputtering of a pure Cu and a pure La targets under N2 atmosphere. The results show that La-free film was composed of Cu3N crystallites with anti-ReO3 structure with (111) texture. The formation of the LaxCu3N films is affected strongly by La, and the peak intensity of the preferred crystalline [111]-orientation decreases with increasing the concentration of La. High concentration of La may prevent the formation of the Cu3N from crystallization. Compared with the Cu3N films, the resistivity of the LaxCu3N films have been decreased. | Xinn'ao Li Jianping Yang Anyou Zuo Zuobin Yuan Zuli Liu Kailun Yao | 2009 | Journal of Materials Science & Technology2009，25，2： | 0 |
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