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| 1 | Global research trends in the microbiome related to irritable bowel syndrome: A bibliometric and visualized study显示文摘BACKGROUND Irritable bowel syndrome(IBS) is a common functional gastrointestinal disorder. Dysregulation of the gut–brain axis plays a central role in the pathophysiology of IBS. It is increasingly clear that the microbiome plays a key role in the development and normal functioning of the gut–brain axis.AIM To facilitate the identification of specific areas of focus that may be of relevance to future research. This study represents a bibliometric analysis of the literature pertaining to the microbiome in IBS to understand the development of this field.METHODS The data used in our bibliometric analysis were retrieved from the Scopus database. The terms related to IBS and microbiome were searched in titles or abstracts within the period of 2000–2019. VOSviewer software was used for data visualization.RESULTS A total of 13055 documents related to IBS were retrieved at the global level. There were 1872 scientific publications focused on the microbiome in IBS. There was a strong positive correlation between publication productivity related to IBS in all fields and productivity related to the microbiome in IBS(r = 0.951, P < 0.001). The United States was the most prolific country with 449(24%) publications, followed by the United Kingdom(n = 176, 9.4%), China(n = 154, 8.2%), and Italy(n = 151, 8.1%). The h-index for all retrieved publications related to the microbiome in IBS was 138. The hot topics were stratified into four clusters:(1) The gut–brain axis related to IBS;(2) Clinical trials related to IBS and the microbiome;(3) Drugmediated manipulation of the gut microbiome;and(4) The role of the altered composition of intestinal microbiota in IBS prevention.CONCLUSION This is the first study to evaluate and quantify global research productivity pertaining to the microbiome in IBS. The number of publications regarding the gut microbiota in IBS has continuously grown since 2013. This finding suggests that the future outlook for interventions targeting the gut microbiota in IBS remains promising. | Sa'ed H Zyoud Simon Smale W Stephen Waring Waleed Sweileh Samah W Al-Jabi | 2021 | World Journal of Gastroenterology2021，27，13： | 2 |
| 2 | Global research on Clostridium difficile-associated diarrhoea:A visualized study显示文摘BACKGROUND Clostridioides(Clostridium)difficile(C.difficile)is still the most common cause of healthcare-associated diarrhoea and is increasing in prevalence as a communityacquired infection.In addition,the emergence of antibiotic resistance in C.difficile can increase the likelihood of the disease developing and/or spreading.AIM To provide an up-to-date picture of the trends in publications related to C.difficile infection,together with specific insights into hot-button issues in this field.METHODS Publications on C.difficile infections in the field of microbiology between 2001 and 2020 were identified from the Scopus database and Reference Citation Analysis.Bibliometric indicators were determined,including the number and type of publications,countries,affiliations,funding agencies,journals and citation patterns.VOSviewer was used to determine research areas and hot-button issues by identifying recurring terms with a high relative occurrence in the title and abstract.RESULTS A total of 8127 documents on‘C.difficile-associated diarrhoea’published between 2001 and 2020 were retrieved from the Scopus database.In the last decade,there has been a significant almost fourfold increase in the number of published papers on this topic.The United States was among the countries(44.11%)with the most publications,and the most involved institution was the University of Leeds in the United Kingdom(2.50%).Three clusters of research were identified and included‘illness spectrum and severity,as well as the signs,symptoms and clinical pathogenesis of C.difficile’;‘laboratory diagnosis and characterization of C.difficile’and‘risk factors for C.difficile infection’.CONCLUSION This study contains the most up-to-date and comprehensive data ever compiled in this field.More international research and cross-institutional collaborations are needed to address more global C.difficile concerns and to benefit from greater sharing of expertise,which will result in higher quality or more effective studies in the future.Promising research avenues in the near future may draw the attention of relevant scientists and funding organizations and open up novel C.difficile infection–based diagnosis and treatment approaches. | Sa'ed H Zyoud | 2022 | World Journal of Gastroenterology2022，28，28： | 2 |
| 3 | Pristine and supported ZnO-based catalysts for phenazopyridine degradation with direct solar light 显示文摘 | Hilal H S A1-Nour G Y M Zyoud A | 2010 | Solid State Sciences2010，12，4： | 1 |
| 4 | Reliability of the reported inges- ted dose of acetaminophen for predicting the risk of toxicity in acet- aminophen overdose patients 显示文摘 | Zyoud SH Awang R Sulaiman SA | 2012 | Pharmacoepidemiol Drug Saf2012，21，2： | 1 |
| 5 | Alternative natural dyes in water purification: Anthocyanin as TiO 2 -sensitizer in methyl orange photo-degradation显示文摘 | Ahed Zyoud Nidal Zaatar Iyad Saadeddin Muath H. Helal Guy Campet Moulki Hakim DaeHoon Park Hikmat S. Hilal | 2011 | Solid State Sciences2011，，6： | 1 |
| 6 | Diabetes mellitus in patients with schizophrenia in West-Bank,Palestine显示文摘 | Sweileh WM Dalal SA Zyoud SH | 2013 | Diabetes Res Clin Pract2013，99，3： | 1 |
| 7 | Pristine and supported ZnO-based catalysts for phenazopyridine degradation with direct solar light显示文摘 | HILAL H S AL-NOUR G Y M ZYOUD A | 2010 | Solid State Sciences2010，12，4： | 1 |
| 8 | Alter- native natural dyes in water purification: Anthocyanin as TiO2-sensitizer in methyl orange photo-degradation 显示文摘 | ZYOUD A ZAATAR N SAADEDDIN L | 2011 | Solid State Sci2011，13，6： | 1 |
| 9 | Availability of treatment resources for the management of acute toxic exposures and poisonings in emergency departments among various types of hospitals in Palestine:a cross-sectional study显示文摘 | Zyoud SH Al-Jabi SW Bali YI | 2014 | Scand J Trauma Resusc Emerg Med2014，21，22： | 1 |
| 10 | Global research production in neonatal abstinence syndrome: A bibliometric analysis显示文摘BACKGROUND Recently,neonatal abstinence syndrome(NAS)emerged as a significant global concern with a dramatic increase in healthcare expenditures.The incidence of the NAS has increased notably in the past decade and emergence as a global public health problem.AIM To evaluate the development and trend of global NAS research from 1958 to 2019 by bibliometric analysis.METHODS Analyzed aspects included publication output per year,language,document types,journals,countries/territories,h-index,authors,and top research priorities.The VOSviewer was used to determine the top research priorities,and trends,and to present bibliometric networks concerning various dimensions,such as coauthorship,authors,and countries.RESULTS A total of 1738 articles were retrieved in the Scopus database from 1958 to 2019.It was found that the great majority of the total NAS documents(n=1295)were original articles followed by reviews(n=268)and letters(n=48).The most productive countries in the NAS field were the United States(n=833),Canada(n=112),the United Kingdom(n=111),and Germany(n=77).Treatment and hospital outcomes in NAS,evidence-based nurse-driven interventions for the care of newborns with NAS,and a systematic reviews and network meta-analysis for therapeutic approaches of NAS were found in recent years(after 2010),compared with terms such as pathophysiology,mechanisms of NAS,and signs and symptoms in the early years.CONCLUSION Treatment and pediatric outcomes and the effectiveness of pharmacological treatment may be frontiers in the NAS field,and continued efforts from researchers are needed in those topics. | Sa'ed H Zyoud Samah W Al-Jabi Moyad Jamal Shahwan Ammar Abdulrahman Jairoun | 2022 | World Journal of Clinical Pediatrics2022，11，3： | 1 |
| 11 | Discharge medications among ischemic stroke survivors显示文摘 | Sweileh W M Sawalha A F Zyoud S H | 2009 | J Stroke Cerebrovasc Dis2009，18，2： | 1 |
| 12 | Parental knowledge, attitudes and practices regarding antibiotic use for acute upper respiratory tract infections in children: a cross - sectional study in palestine 显示文摘 | Zyoud SH Abu Taha A Araj KF | 2015 | BMC Pediatr2015，1，15： | 1 |
| 13 | 显示文摘 | Zyoud A Zaatar N Saadeddin I | 2011 | Solid State Sciences2011，13，： | 1 |
| 14 | Alternative natural dyes in water purifi- cation: Anthocyanin as TiO2-sensitizer in methyl orange photo-degradation显示文摘 | Zyoud A H | 2011 | Solid State Sci2011，13，6： | 1 |
| 15 | Bronchial asthma and chronic obstructive pubnonary disease: research activity in Arab countries 显示文摘 | Sweileh WM A1 -Jabi SW Zyoud SH | 2014 | Multidiscip Respir Med2014，9，1： | 1 |
| 16 | Pristine and supported ZnO-based catalysts for phenazopyridine degra- dation with direct solar lig)tt 显示文摘 | Hilal H S A1-Nour G Y M Zyoud A | 2010 | Solid State Sciences2010，12，4： | 1 |
| 17 | Mapping the landscape and structure of global research on binge eating disorder:Visualization and bibliometric analysis显示文摘BACKGROUND Binge-eating disorder(BED)is a clinical syndrome and is considered the most common type of eating disorder.However,our understanding of the global performance and progress of BED research is limited.AIM To describe and perform a bibliometric analysis of the state of BED research.METHODS The term‘Binge eating’was searched in the title throughout the previous year’s up to December 31,2020.We searched the Scopus and Reference Citation Analysis for publications on Binge eating.The VOSviewer software version 1.6.17 was used to produce the network visualization map of the most frequent author,collaborative relationships between countries/regions,and to determine the hotspots related to binge eating research.In addition,conventional bibliometric indicators were generated.RESULTS The search strategy found 2713 total articles and an average of 62 articles per year.Among them,‘Article’represented 82.49%of the publications(n=2238 articles)and was the most frequent type,followed by reviews(n=243;8.96%).The number of publications increased steadily during the last decade of the study period.One hundred and thirty-two countries contributed to binge eating research,with 1495(55.11%)articles published in the United States,followed by Italy with 256(9.44%),the United Kingdom with 183(6.75%),and Germany with 182(6.71%).Currently,the main hot topics related to BED are‘type of treatment and management and treatment provided to BED”;“processes and pathways to binge eating”;and‘diagnosis,signs and symptoms,comorbidities and prevalence and associated factors with BED’.CONCLUSION The number of publications has increased noticeably during the previous decade.There are indeed relatively few publications on BED from low-and middle-income nations,so much is to be learned from the experience of all countries.Studies on this topic are critical in all countries to discover risk factors and effective intervention measures.Although our findings are preliminary,they imply that the future prospects for interventions aimed at BED management are bright,focusing on complex models of care and long-term maintenance of therapeutic gains. | Sa'ed H Zyoud Muna Shakhshir Amani S Abushanab Amer Koni Moyad Shahwan Ammar AbdulrahmanJairoun Samah W Al-Jabi | 2022 | World Journal of Psychiatry2022，12，7： | 0 |
| 18 | Global trends in research related to sleeve gastrectomy:A bibliometric and visualized study显示文摘BACKGROUND One of the most popular bariatric procedures is sleeve gastrectomy,and it has become significantly more common in recent years.AIM To evaluate the research activity in sleeve gastrectomy over the last two decades,and to visualize the hot spots and emerging trends in this type of bariatric surgeryusing bibliometric methods.METHODS The Scopus database was used to search for publications related to sleeve gastrectomy.The retrieved publications were reviewed in terms of year of publication,type of study,country of origin,institutions,journals,and citation patterns by using descriptive analysis.Collaboration network and term cooccurrence analysis were visualized by using VOSviewer software.RESULTS The search strategy yielded a total of 6508 publications on sleeve gastrectomy from 2001 to 2020.As regards the document type,the majority were articles(n=5230;80.36%),followed by reviews(n=544;8.36%).The top three countries are the United States,with 1983 publications(30.47%),followed by France(600;9.22%)and Italy(417;6.71%).The most cited publication was published in 2012 by Schauer et al in the New England Journal of Medicine(n=1435 citations).This publication found that weight loss was greater in the sleeve gastrectomy group than in the medical therapy group.Furthermore,this study demonstrated that 12 mo of medical therapy plus bariatric surgery greatly improved glycemic regulation in obese patients with uncontrolled type 2 diabetes compared with medical therapy alone.The focus of the current literature on sleeve gastrectomy was directed toward several themes such as morbidity and potential complications,the complexity of the procedure and different surgical approaches,and diabetes and body mass index in correlation to sleeve gastrectomy.CONCLUSION The number of sleeve gastrectomy publications has gradually grown over the last 20 years.This bibliometric analysis could help researchers better understand the knowledge base and research frontiers surrounding sleeve gastrectomy.In addition,future studies may focus on emerging research hotspots. | Abdulkarim Barqawi Faris AK Abushamma Maha Akkawi Samah W Al-Jabi Moyad Jamal Shahwan Ammar Abdulrahman Jairoun Sa'ed H Zyoud | 2021 | World Journal of Gastrointestinal Surgery2021，13，11： | 0 |
| 19 | Current global research landscape on COVID-19 and cancer: Bibliometric and visualization analysis显示文摘BACKGROUND Cancer is a severe public health issue that seriously jeopardizes global health.In individuals with coronavirus disease 2019(COVID-19),cancer is considered an independent risk factor for severe illness and increased mortality.AIM To identify research hotspots and prospects,we used bibliometrics to examine the global production of COVID-19 literature published in the field of oncology.METHODS Data on publication output were identified based on the Scopus database between January 1,2020,and June 21,2022.This study used VOSviewer to analyze collaboration networks among countries and assess the terms most often used in the titles and abstracts of retrieved publications to determine research hotspots linked to cancer and COVID-19.The Impact Index Per Article for the top 10 high-cited papers collected from Reference Citation Analysis(RCA)are presented.RESULTS A total of 7015 publications were retrieved from the database.The United States published the greatest number of articles(2025;28.87%),followed by Italy(964;13.74%),the United Kingdom(839;11.96%),and China(538;7.67%).The University of Texas MD Anderson Cancer Center(n=205,2.92%)ranked first,followed by the Memorial Sloan-Kettering Cancer Center(n=176,2.51%).The European Journal of Cancer(n=106,1.51%)ranked first,followed by the Frontiers in Oncology(n=104,1.48%),Cancers(n=102,1.45%),and Pediatric Blood and Cancer(n=95;1.35%).The hot topics were stratified into“cancer care management during the COVID-19 pandemic”;and“COVID-19 vaccines in cancer patients”.CONCLUSION This is the first bibliometric analysis to determine the present state and upcoming hot themes related to cancer and COVID-19 and vice versa using VOSviewer during the early stages of the pandemic.The emergence of hot themes related to cancer and COVID-19 may aid researchers in identifying new research areas in this field. | Sa'ed H Zyoud Amer Koni Samah W Al-Jabi Riad Amer Muna Shakhshir Rand Al Subu Husam Salameh Razan Odeh Sultan Musleh Faris Abushamma Adham Abu Taha | 2022 | World Journal of Clinical Oncology2022，13，10： | 0 |
| 20 | Mapping the global research landscape on insulin resistance: Visualization and bibliometric analysis显示文摘BACKGROUND Insulin resistance is a risk factor for metabolic syndromes and is associated with a wide variety of metabolic illnesses,including obesity,type 2 diabetes,and cardiovascular disease.AIM To investigate and map global insulin resistance studies.METHODS A bibliometric methodology was applied to the literature retrieved from the Scopus database and Reference Citation Analysis(http://gffzzb1f9d057b5954674svbcppncwvnvv6wqc.ffgz.tsg.suse.edu.cn)by using a validated search strategy.The study period was limited from 2002 to 2021.Bibliometric indicators and mapping were presented.RESULTS A total of 26808 articles on the topic of insulin resistance were included in the Scopus database.The articles included research articles(n=21918;81.76%),review articles(n=2641;9.85%),and letters(n=653;2.44%).During the study period,136 countries contributed to the research on insulin resistance.The highest number of articles was from the United States(n=7360;27.45%),followed by China(n=3713;13.85%),Japan(n=1730,6.45%),Italy(n=1545;5.54%),and the United Kingdom(n=1484;5.54%).The retrieved articles identified two main research themes:“inflammatory mechanisms in the regulation of insulin resistance”and“mechanisms linking obesity to insulin resistance”.CONCLUSION Our data show that insulin resistance has steadily gained interest from researchers,as evidenced by the number of citations and yearly publications.Publications have grown significantly in the last decade,while low-income countries with greater burdens continue to produce fewer publications in this field.This approach might assist researchers in choosing new research areas and recognizing research hotspots and frontiers.In the future,perhaps high-quality clinical evidence will be acquired. | Sa’ed H Zyoud Muna Shakhshir Amer Koni Amani S Abushanab Moyad Shahwan Ammar Abdulrahman Jairoun Rand Al Subu Adham Abu Taha Samah W Al-Jabi | 2022 | World Journal of Diabetes2022，13，9： | 0 |
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