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| 1 | GDNF-Enhanced Axonal Regeneration and Myelination Following Spinal Cord Injury is Mediated by Primary Effects on Neurons显示文摘我们先前研究表明胶质细胞源性神经营养因子(GDNF)联合施万细胞移植能促进脊髓损伤后轴突再生和髓鞘形成。然而,GDNF介导这一过程的细胞靶点尚不清楚。在此,我们报道了GDNF可增加在体再生轴突的数目和直径,并促进体外背根神经节神经元的轴突向外生长,提示GDNF对神经元有直接作用。在施万细胞-背根神经节神经元共培养下,GDNF显著增加施万细胞生成的髓鞘数目;GDNF处理对孤立培养的施万细胞增殖无作用,但可促进已与神经轴突有突触联系的施万细胞增殖;GDNF可增加孤立施万细胞中分子量为140kDa的神经细胞黏附分子(NCAM)的表达,但对黏附分子L1表达或神经营养因子NGF、NT3及BDNF分泌没有影响。总之,这些结果支持假设:GDNF提高轴突再生和施万细胞髓鞘形成主要是通过GDNF对神经元的直接作用介导的,并且提示GDNF联合施万细胞移植可能是促进脊髓损伤后轴突再生和髓鞘形成的有效策略之一。 | LIQUN ZHANG ZHENGWEN MA GEORGE M. SMITH XUEJUN WEN YELENA PRESSMAN PATRICK M. WOOD AND XIAO-MING XU | 2009 | 神经损伤与功能重建2009，4，4： | 25 |
| 2 | Serological diagnosis of nasopharyngeal carcinoma by enzyme linked immunosorbant assay:optimization,standardization and diagnostic criteria显示文摘Serologicaldiagnosisofnasopharyngealcarcinomabyenzymelinkedimmunosorbantasay:optimization,standardizationanddiagnosticcriteri... | M.H. Ng, H.L. Chen, R.X. Luo, K.H. Chan, P.C.Y. Woo, J.S.T. Sham, J. Huang, W.H.Seto P. Smith and B.E. Griffin | 1998 | Chinese Medical Journal1998，，6： | 8 |
| 3 | HIGH-ENERGY IONS PRODUCED IN EXPLOSIONS OF SUPERHEATED ATOMIC CLUSTERS显示文摘 | T Ditmire J W G Tisch E Springate M B Mason N Hay R A Smith J Marangos and M H R Hutchinson | | 0，，： | 4 |
| 4 | Genetic influences on beef longissimus palatability in Charolais-and Limousin-sired steers and heifers显示文摘 | Wulf D M Tatum J D Green R D Morgan J B Golden B L and Smith G C | 1996 | J Anim Sci1996，74，： | 2 |
| 5 | Adverse selection, aggregate uncertainty, and the role for mutual insurance contracts 显示文摘 | Smith Bruce and Stutzer Michael | 1990 | Journal of Business1990，63，： | 1 |
| 6 | Leptin signaling in the hypothalamus of normal rats in vivo显示文摘 | Mccowen K C Chow J C and Smith R J | 1998 | Endocrinology1998，139，11： | 1 |
| 7 | The ASA framework: An update显示文摘 | Schneider B Goldstein H W and Smith D B | 1995 | Personnel Psychology1995，48，4： | 1 |
| 8 | Adverse selection, aggregate uncertainty, and the role for mutual insurance con- tracts 显示文摘 | Smith B D and Stutzer M | 1990 | Journal of Business1990，63，4： | 1 |
| 9 | Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association con- ference on scientific issues related to definition 显示文摘 | Grundy SM Brewer HB Jr Cleeman JI Smith SC Jr Lenfant C American Heart Association National Heart Lung and Blood In- stitute | 2004 | Circulation2004，109，3： | 1 |
| 10 | A finite element model for the shape development of irregular planar cracks显示文摘 | Smith R A and Cooper J F | 1989 | Int J Pres Ves and Piping1989，36，4： | 1 |
| 11 | Monoclonal immunoglobin light chain in urine of patients with B lymphocytic disease:its source and use as a diagnostic aid显示文摘 | Stevenson FK Speelerberg M and Smith JL | 1983 | Br J Cancer1983，47，： | 1 |
| 12 | Closed-form least-squares source location estimation from range-difference measurements 显示文摘 | Smith J O and Abel J S | 1987 | IEEE Transactions on Acoustics Speech and Signal Processing1987，35，12： | 1 |
| 13 | Composite Medium with Simultaneously Negative Permeability and Permittivity 显示文摘 | Smith D R Padilla W J and Vier D C | 2001 | Physical Review Letters2001，84，18： | 1 |
| 14 | The impact of media coverage on the transmission dynamics of human influenza显示文摘 | Tchuenche J M Dube N Bhunu C P Smith R J and Banch C T | 2011 | BMC Public Health2011，，11： | 1 |
| 15 | Instantaneous ca- pacity of OFDM on Rayleigh-Fading channels 显示文摘 | Clark A Smith P J and Taylor D P | 2007 | IEEE Transactions on Information Theory2007，53，1： | 1 |
| 16 | Comparison of parametric and nonparametric models for traffic flow forecasting显示文摘 | Brian L Smith Billy M Williams and R Keith Oswald | 2002 | Transportation Research Part C: Emerging Technologies2002，10，4： | 1 |
| 17 | In search of predatory pricing 显示文摘 | Isaac R Mark and Vernon L Smith | 1985 | Journal of Political Economy1985，93，： | 1 |
| 18 | Phytoremediation of metals:using plants to remove pollutants from the environment 显示文摘 | Raskin l Smith R D and Salt D E | 1997 | Current Opinion in Biotechnology1997，8，： | 1 |
| 19 | Experimental verification of a negative index of refraction显示文摘 | R Shelby D R Smith and S Schultz | 2001 | Science2001，292，： | 1 |
| 20 | Deposition of atmospheric pollutants to the LOIS area显示文摘 | Smith R I Cape J N Binnie J Murray T D Young M and Fowler D | 1997 | Science of the Total Environment1997，，： | 1 |
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