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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | 显示文摘 | Lima M D de Andrade M J Bergmann C P | 2008 | J Mater Chem2008，18，： | 1 |
| 3 | Ultrasound guided core needle biopsy of breast masses: How many cores are necessary to diagnose cancer? 显示文摘 | De Lucena C E Dos Santos Junior J L De Lima Resende C A | 2007 | J Clin Ultrasound2007，35，7： | 1 |
| 4 | Memantine reduces oxidative damage and enhances long-term recognition memory in aged rats显示文摘 | Pietá Dias C Martins de Lima MN Presti-Torres J | | 0，，04： | 1 |
| 5 | The use of response surface methodology in optimization of lactic acid production: focus on medium supplementation, temperature and pH control显示文摘 | de LIMA C J B COELHO L F CONTIERO J | 2010 | Food Technology and Biotechnology2010，48，2： | 1 |
| 6 | Benefits of soy isoflavone therapeutic regimen on menopausal symptoms显示文摘 | Han K K Soares J M Haidar M A Rodrigues de Lima G Baracat E C | 2002 | Obstet Gynecol2002，99，3： | 1 |
| 7 | Eu3+ en-trapped in alumina matrix obtained by hydrolytic and non-hydrolytic sol-gel Routes显示文摘 | Ciuffi K J de Lima O J Sacco H C | 2002 | Journal of Non-Crystalline Solids2002，304，： | 1 |
| 8 | The Effect of Glutamine Supplementation on the Function of Neutrophils from Exercised Rats显示文摘 | Lagranha C J de Lima T M Senna S M | | 0，，： | 1 |
| 9 | Heart rate monitoring in soccer:interest and limits during competitive match play and training, practical applica- tion显示文摘 | Alexandre D da Silva C D Hill-Haas S Wong del P Natali A J De Lima J R Bara Filho M G Matins J J Garcia E S Karim C | 2012 | J Strength Cond Res2012，26，10： | 1 |
| 10 | Nonlinear dynamic analysis of steel portal frames with semi rigid connections 显示文摘 | da Silva J G S de Lima L R O da S Vellasco P C G | 2008 | Engineering Structures2008，30，9： | 1 |
| 11 | Heart rate monitoring in soccer: interest and limits during competitive match play and training, practical applica- tion显示文摘 | Alexandre D da Silva C D Hill-Haas S Wong del P Natali A J De Lima J R Bars Filho M G Matins J J Garcia E S Karim C | 2012 | J Strength C ond Res2012，26，10： | 1 |
| 12 | Production of rennet in submerged fermentation with the filamentous fungus Mucor miehei NRRL 3420显示文摘 | DE LIMA C J B CORTEZI M LOVAGLIO R B | 2008 | World Applied Science Journal2008，4，： | 1 |
| 13 | D( - )-lac- tic acid production by Leuconostoc mesenteroides B512 using different carbon and nitrogen sources 显示文摘 | Coelho L F de Lima C J Bernardo M P | 2011 | Applied Bio- chemistry and Biotechnology2011，164，7： | 1 |
| 14 | On the use of PCA in GMM and AR-Vector models for text independ spreaker verification显示文摘 | DE LIMA C B ABRAHAM A AOPLINARIO J A Jr | 1997 | Proceedings of the IEEE1997，85，9： | 1 |
| 15 | Human papillomavirus genotype attribution in invasive cervical cancer:a retrospective cross-sectional worldwide study显示文摘 | de Sanjose S Quint WG Alemany L Geraets DT Klaustermeier JE Lloveras B Tous S Felix A Bravo LE Shin HR Vallejos CS de Ruiz PA Lima MA Guimera N Clavero O Alejo M Llombart-Bosch A Cheng-Yang C Tatti SA Kasamatsu E Iljazovic E Odida M Prado R Seoud M Grce M Usubutun A Jain A Suarez GA Lombardi LE Banjo A Menéndez C Domingo EJ Velasco J Nessa A Chichareon SC Qiao YL Lerma E Garland SM Sasagawa T Ferrera A Hammouda D Mariani L Pelayo A Steiner I Oliva E Meijer CJ AlJassar WF Cruz E Wright TC Puras A Llave CL Tzardi M Agorastos T Garcia-Barriola V Clavel C Ordi J Andújar M Castellsagué X Sánchez GI Nowakowsld AM Bornstein J Mu(n)oz N Bosch FX Retrospective International Survey and HPV Time Trends Study Group | 2010 | Lancet Oncol2010，11，11： | 1 |
| 16 | XRF applications in archaeometry:Analysis of Marajoara pubic covers and pigments from the sarcophagus cartonage of an Egyptian mummy显示文摘 | Calza C Anjos M J Bueno M I M S de Souza S M Brancaglion Jr A Lima T A Lopes R T | | 0，，05： | 1 |
| 17 | Matrix effect in guava multiresidue analysis by QuEChERS method and gas chromatography coupled to quadrupole mass spectrometry显示文摘 | GUEDES J A C DE OLIVEIRA SILVA R LIMA C G | 2016 | Food Chem2016，199，： | 1 |
| 18 | The primary chilling of poultry carcassesd-a review显示文摘 | James C Vincent C T I de Andrade Lima James S J | 2006 | International Journal of Refrigeration2006，29，： | 1 |
| 19 | Impact of taurine supplementation on blood pressure in gestational protein-re- stricted offspring: Effect on the medial solitary tract nucleus cell numbers, angiotensin receptors, and renal sodium han- dling显示文摘 | Scabora J E de Lima M C Lopes A | 2015 | J Renin Angiotensin Aldosterone Syst2015，16，1： | 1 |
| 20 | Tunable fre- quency selective surface using liquid substrates显示文摘 | Lima A C de C Parker E A Langley R J | 1994 | Electron Lett1994，30，4： | 1 |
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