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| 1 | Endoscopic ultrasound-guided vs endoscopic retrograde cholangiopancreatography biliary drainage for obstructed distal malignant biliary strictures: A systematic review and meta-analysis显示文摘BACKGROUND For palliation of malignant biliary obstruction(MBO), the gold-standard method of biliary drainage is endoscopic retrograde cholangiopancreatography(ERCP)with the placement of metallic stents. Endoscopic ultrasound(EUS)-guided drainage is an alternative that is typically reserved for cases of ERCP failure.Recently, however, there have been robust randomized clinical trials(RCTs)comparing EUS-guided drainage and ERCP as primary approaches to MBO.AIM To compare EUS guidance and ERCP in terms of their effectiveness and safety in palliative biliary drainage for MBO.METHODS This was a systematic review and meta-analysis, in which we searched the MEDLINE, Excerpta Medica, and Cochrane Central Register of Controlled Trials databases. Only RCTs comparing EUS and ERCP for primary drainage of MBO were eligible. All of the studies selected provided data regarding the rates of technical and clinical success, as well as the duration of the procedure, adverse events, and stent patency. We assessed the risk of biases using the Jadad score and the quality of evidence using the Grading of Recommendations Assessment,Development and Evaluation criteria.RESULTS The database searches yielded 5920 records, from which we selected 3 RCTs involving a total of 222 patients(112 submitted to EUS and 110 submitted to ERCP). In the EUS and ERCP groups, the rate of technical success was 91.96%n and 91.81%, respectively, with a risk difference(RD) of 0.00%(95%CI:-0.07, 0.07;P = 0.97; I^2 = 0%). The clinical success was 84.81% and 85.53% in the EUS and ERCP groups, respectively, with an RD of-0.01%(95%CI:-0.12, 0.10; P = 0.90; I^2 =0%). The mean difference(MD) for the duration of the procedure was-0.12%(95%CI:-8.20, 7.97; P = 0.98; I^2 = 84%). In the EUS and ERCP groups, there were14 and 25 adverse events, respectively, with an RD of-0.06%(95%CI:-0.23, 0.12; P= 0.54; I^2 = 77%). The MD for stent patency was 9.32%(95%CI:-4.53, 23.18; P =0.19; I^2 = 44%). The stent dysfunction rate was significantly lower in the EUS t group(MD =-0.22%; 95 CI:-0.35,-0.08; P = 0.001; I^2 = 0%).CONCLUSION EUS represents an interesting alternative to ERCP for MBO drainage,demonstrating lower stent dysfunction rates compared with ERCP. Technical and clinical success, duration, adverse events and patency rates were similar. | Fernanda P Logiudice Wanderlei M Bernardo Facundo Galetti Vitor M Sagae Carolina O Matsubayashi Antonio C Madruga Neto Vitor O Brunaldi Diogo T H de Moura Tomazo Franzini Spencer Cheng Sergio E Matuguma Eduardo G H de Moura | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，4： | 6 |
| 2 | Clinical significance of'anti-HBc alone'in human immunodeficiency virus-positive patients显示文摘AIM:To determine the prevalence and clinical relevance of isolated antibodies to hepatitis B core antigen as the only marker of infection('anti-HBc alone')among human immunodeficiency virus(HIV) type-1 infected patients.Occult hepatitis B infection frequency was also evaluated. METHODS:Three hundred and forty eight histories from 2388 HIV-positive patients were randomly reviewed.Patients with serological markers of hepatitis B virus(HBV)infection were classified into three groups:past hepatitis,'anti-HBc alone'and chronic hepatitis.Determination of DNA from HBV,and RNA and genotype from hepatitis C virus(HCV)were performed on'anti-HBc alone'patients. RESULTS:One hundred and eighty seven(53.7%) HIV-positive patients had markers of HBV infection: 118 past infection(63.1%),14 chronic hepatitis (7.5%)and 55'anti-HBc alone'(29.4%).Younger age[2.3-fold higher per every 10 years younger;95% confidence intervals(CI)1.33-4.00]and antibodies to HCV infection[odds ratio(OR)2.87;95%CI 1.10-7.48]were factors independently associated with the'anti-HBc alone'pattern.No differences in liver disease frequency were detected between both groups. Serum levels of anti-HBs were not associated with HCV infection(nor viral replication or HCV genotype),or with HIV replication or CD4 level.No'anti-HBc alone' patient tested positive for HBV DNA. CONCLUSION:'Anti-HBc alone'prevalence in HIVpositive patients was similar to previously reported data and was associated with a younger age and with antibodies to HCV infection.In clinical practice,HBV DNA determination should be performed only in those patients with clinical or analytical signs of liver injury. | M~aTeresa Pérez-Rodríguez Bernardo Sopea Manuel Crespo Alberto Rivera Teresa González del Blanco Antonio Ocampo César Martínez-Vázquez | 2009 | World Journal of Gastroenterology2009，15，10： | 2 |
| 3 | Usefulness of biodegradable polydioxanone stents in the treatment of postsurgical colorectal strictures and fistulas显示文摘 | F. Pérez Roldán P. González Carro M. Villafá?ez García S. Aoufi Rabih M. Legaz Huidobro N. Sánchez-Manjavacas Mú?oz O. Roncero García-Escribano M. Ynfante Ferrús E. Bernardos Martín F. Ruiz Carrillo | 2012 | Endoscopy2012，，03： | 2 |
| 4 | Bifurcations of dynamical systems with sliding: derivation of normal form mapping显示文摘 | di Bernardo M Kowalczyk P Nordmark A | 2002 | Phys D2002，170，17： | 1 |
| 5 | Architecting families of software systems with process algebras 显示文摘 | Bernardo M Ciancarini P Donatiello L | 2002 | ACM Trans on Software Engineering and Methodology2002，11，4： | 1 |
| 6 | Architecling families of software systems with process algebras 显示文摘 | Bernardo M Ciancarini P Donatiello L | 2002 | ACM Transactions on Software Engineering and Methodology2002，11，4： | 1 |
| 7 | Bifurcations in non-smooth dynamical systems显示文摘 | di Bernardo M Budd C Champneys A R Kowalczyk P Nordmark A B Olivvar G Piiroinen P T | 2008 | SIAM Review2008，50，4： | 1 |
| 8 | Weighted least squares techniques for improved received signal strength based localizatinn显示文摘 | TARRIO P BERNARDOS A M CASAR J R | 2011 | Sensors2011，11，9： | 1 |
| 9 | Theoretical energy performance evaluation of different single stage vapour compression refrigeration configurations using R1234yf and R1234ze(E) as working fluids 显示文摘 | FRANCISCO M JOAQUIN N E BERNARDO P | 2014 | International Journal of Refrigeration2014，44，1： | 1 |
| 10 | Minimal control synthe-sis adaptive control of chaos nonlinear systems:utili-zing the properties of chaos显示文摘 | Bernardo M D Stoten D P | 2006 | Phil Trans R Soc A2006，64，： | 1 |
| 11 | Architecting families of software systems with process algebras显示文摘 | BERNARDO M CIANCARINI P DONATIELLO L | 2002 | ACM Transactions on Software Engineering and Methodology2002，11，4： | 1 |
| 12 | MRI of tumor angiogenesis显示文摘 | Barrett T Brechbiel M Bernardo M Choyke P L | 2007 | J Magn Reson Imaging2007，26，： | 1 |
| 13 | 3-D computational fluiddynamics for gas and gas-particle flows in a cyclone withdifferent inlet section angles显示文摘 | Bernardo S Mori M Peres A P | 2006 | Powder Technology2006，162，3： | 1 |
| 14 | Adaptive synchronization of complex networks显示文摘 | Lellis P D Bernardo M D Sorrentino F | | 0，，08： | 1 |
| 15 | Synchronization of complex networks through local adaptive coupling显示文摘 | Lellis P D Bernardo M D Garofalo F | | 0，，03： | 1 |
| 16 | Novel decentralized adaptive strategies for the synchronization of complex networks显示文摘 | Lellis P D Bernardo M D Garofalo F | | 0，，05： | 1 |
| 17 | Architectingfamilies of software systems with process algebras显示文摘 | BERNARDO M CIANCARINI P DONATIELLO L | 2002 | ACM Transon Software Engineering and Methodology2002，11，4： | 1 |
| 18 | Architecting families of software systems with process algebras显示文摘 | Bernardo M Ciancarini P Lorenzo D | 2002 | ACM Transactions on Software Engineering and Methodology2002，11，4： | 1 |
| 19 | D( - )-lac- tic acid production by Leuconostoc mesenteroides B512 using different carbon and nitrogen sources 显示文摘 | Coelho L F de Lima C J Bernardo M P | 2011 | Applied Bio- chemistry and Biotechnology2011，164，7： | 1 |
| 20 | Antimicrobialresistance in Escherichia coli isolated in wastewater and sludge frompoultry slaughterhouse wastewater plants显示文摘 | DA COSTA P M VAZ-PIRES P BERNARDO F | 2008 | Journal ofEnvironment Health2008，70，45： | 1 |
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