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1D-二聚体预测稳定型冠状动脉性心脏病患者的长期病因特异性死亡率、心血管事件和癌症显示文摘交联纤维蛋白的降解产物D-二聚体是高凝状态和血栓形成事件的标志。D-二聚体水平中度升高与血管疾病患者静脉和动脉事件的风险相关。在缺血性疾病长期普伐他汀干预(long-term intervention with pravastatin in ischemic disease,LIPID)试验中,研究者在存在其他危险因素的背景下,评估了D-二聚体水平在预测长期血管转归、病因特异性死亡率和新发癌症中的作用。刘青 叶鹏 Simes J Robledo KP White HD Espinoza D Stewart RA Sullivan DR Zeller T Hague W Nestel PJ Glasziou PP Keech AC Elliott J Blankenberg S Tonkin AM LIPID study investigators 2018中华高血压杂志2018,26,3:6
2Self-Healing Concrete with Crystalline Admixture——A Review显示文摘The scope of the present paper is to understand the effects of crystalline admixture on the selfhealing capacity of the cementitious composites. Previous studies were examined and a conclusion was drawn to the effect that different additives to crystalline admixture tend to improve self-healing of concrete for larger cracks. It is recommended that initial treatment with chemical admixture can stimulate and heal further cracks and it has the better repeatability trend in mixing with the concretes and mechanical recovery is possible even under repetitive preloading. Effective self-healing with chemical admixtures even under open-air exposure, leads to study the importance of a service ability design parameter including the maximum allowable crack width by repeatability analysis as a function of the exposure with the concept of sealable crack width.A Ravitheja Dr T Chandra Sekhara Reddy Dr C Sashidhar 2019Journal of Wuhan University of Technology(Materials Science)2019,34,5:6
3Migration of retinal pigment epithelium cells in vitro is regulated by protein kinase C显示文摘Murphy TL Sakamoto T Hinton DR 1995Exp Eye Res1995,60,6:2
4胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
5Tumor necrosis factor and interleukin-6 mRAN expression in neonatal Lewvis rat Schwann cells显示文摘 Zaheer T Zhong W 1991Marcel Dekker Ink1991,72,1:1
6Lamotrigine:a review of its use in bipolar disorder显示文摘Goldsmith DR Wagstaff AJ Ibbotson T 2003Drugs2003,63,19:1
7The S4-S5 linker directly couples voltage sensor movement to the activation gate in the human ether-a'-go-go-related gene (hERG) K+ channel显示文摘Ferrer T Rupp J Piper DR 2006J Biol Chem2006,281,12:1
8Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor protiens显示文摘Borchelt DR Ratovitski T Van Lare J 1997Neuron1997,19,:1
9A shared chemical basis of avian hostparasite egg colour mimicry显示文摘Igic B Cassey P Grim T Greenwood DR Moskát C Rutila J Hauber ME 0,,:1
10A randomized comparison of a five-minute versus fifteen- minute lockout interval for PCEA during labor显示文摘Stratmann G Gambling DR Moeller-Bertram T 2005Int Ob- stetAnesth2005,14,3:1
11Linked chromosome 16q13 chemokines, macrophage derived chemokine, ractalkine, and thymus and activation regulated ehemokine, are expressed in human atherosclerotic lesions显示文摘Greaves DR Hakkinen T Lucas AD 2001Arterioscler Thromb Vasc Biol2001,21,6:1
12MicroRNAs and the hallmarks of cancer显示文摘Dalmay T Edwards DR 2006Oncogene2006,25,46:1
13Fiber optic sensor technology : An overview 显示文摘Granttan K T V Dr Sun T 2000Sensor and Actuators2000,82,1:1
14Epstein-Barr virus myo- carditis as a cause of sudden death: two autopsy cases显示文摘Ishikawa T Zhu BL Li DR 2005Int J Legal Med2005,119,4:1
15P450 superfamilys update on new sequences,gine mapping,accession number and nomenclature显示文摘Nelson DR Koymaus L Kamataki T 1996Pharmacogenetics1996,6,1:1
16Percutaneous ethanol injection in the treatment of hepatocellular carcinoma in cirrhosis显示文摘Livraghi T Servizio DR Civil O 2001Hepato-Gastroenterology2001,48,1:1
17Caspase functions in cell death and disease显示文摘Mcllwain DR Berger T Mak TW 2013Cold Spring Harbor Perspect Biol2013,5,00:1
18Endotoxin-induced cytokine gene expression and excretion in the liver 显示文摘Luster MI Germolec DR Yoshida T 1994Hepatology1994,19,:1
19Have outcomes of incisional hernia repair improved with time?A populationbased analysis显示文摘Flum DR Horvath K Koepsell T 2003Ann Surg2003,237,1:1
20Japanese-US common-arm analysis of paclitaxel plus carboplatin in advanced non-small-cell lung cancer:a model for assessing population-related pharmacogenomics显示文摘Gandara DR Kawaguchi T Crowley J 2009Clin Oncol2009,27,21:1
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