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44篇 您的检索式:作者名="xufeng chen"
    题名 作者 年代 出处 被引量
1Prognostic significance of VEGF-C expression in correlation with COX-2, lymphatic microvessel density, and clinicopathologic characteristics in human non-small cell lung cancer显示文摘因为高发生和高死亡,肺癌症是在中国的最致命的癌症之一。Cyclooxygenase-2 (COX-2 ) 和容器 endothelial 生长因素 C (VEGF-C ) 被发现在恶意的肿瘤的 lymphangiogenesis 起一个重要作用。在这研究,我们调查了淋巴的 microvessel 密度(LMVD ) 是否与在非小的房间肺癌症(NSCLC ) 的预后有关是 COX-2 和 VEGF-C 的病人,和表情以便在 NSCLC lymphangiogenesis 决定 COX-2 和 VEGF-C 的可能的角色。嵌入的织物 NSCLC 取样的 65 修理福尔马林的石蜡被染色的 immunohistochemical 为 COX-2 和 VEGF-C 评估。估计肿瘤 lymphangiogenesis, LMVD 被 immunohistochemical 染色 VEGFR-3 polyclonal 决定抗体。在 COX-2 和 VEGF-C 表示, LMVD,和 clinicopathologic 参数之中的关系被分析。在 65 件样品之中,高 LMVD 显著地与淋巴节点转移和差的幸存被联系。Multivariate 幸存分析证明那 LMVD 价值和淋巴节点转移是独立预示的因素。COX-2 和 VEGF-C 的表示水平比邻近的纸巾的那些显著地高。在 NSCLC 的 COX-2 和 VEGF-C 表情显著地与淋巴节点转移,然而并非与耐心的性,年龄,肿瘤尺寸,或肿瘤相关,节点,转移分类舞台。COX-2- 或 VEGF-C-positive 肿瘤的吝啬的 LMVD 价值比 COX-2- 或 VEGF-C-negative 肿瘤的高。重要关联在 COX-2 和 VEGF-C 的表情之间被发现。这研究建议 LMVD 可以是为 NSCLC 病人的重要预示的因素之一。VEGF-C 可能在 COX-2 lymphangiogenic 小径起一个重要作用。COX-2 和 VEGF-C 可以由刺激 lymphangiogenesis 在肿瘤前进起一个重要作用。lymphangiogenesis, COX-2,或 VEGF-C 活动的抑制可以在 NSCLC 的控制有一个重要治疗学的好处。Xufeng Guo Yongbing Chen Zhonghua Xu Zhonghen Xu Yongyue Qian Xueyan Yu 2009Acta Biochimica et Biophysica Sinica2009,41,3:34
2Real-time drogue recognition and 3D locating for UAV autonomous aerial refueling based on monocular machine vision显示文摘Drogue recognition and 3D locating is a key problem during the docking phase of the autonomous aerial refueling(AAR). To solve this problem, a novel and effective method based on monocular vision is presented in this paper. Firstly, by employing computer vision with red-ring-shape feature, a drogue detection and recognition algorithm is proposed to guarantee safety and ensure the robustness to the drogue diversity and the changes in environmental conditions, without using a set of infrared light emitting diodes(LEDs) on the parachute part of the drogue. Secondly, considering camera lens distortion, a monocular vision measurement algorithm for drogue 3D locating is designed to ensure the accuracy and real-time performance of the system,with the drogue attitude provided. Finally, experiments are conducted to demonstrate the effectiveness of the proposed method. Experimental results show the performances of the entire system in contrast with other methods, which validates that the proposed method can recognize and locate the drogue three dimensionally, rapidly and precisely.Wang Xufeng Kong Xingwei Zhi Jianhui Chen Yong Dong Xinmin 2015Chinese Journal of Aeronautics2015,28,6:15
3Risk analysis of snow disaster in the pastoral areas of the Qinghai-Tibet Plateau显示文摘雪灾难是顶之一世界范围的十自然灾难,和最严重的自然灾难到影响 Qinghai 西藏高原的牧剧区域。基于从历史的记录收集的危险伤害数据和从这危险在 2010 影响的实体收集的数据,Qinghai西藏高原上的雪灾难的 18 个索引的全面分析被进行,包含危险伤害,物理暴露的数量忍受危险的实体脸,敏感到危险,和能力到对灾难作出回应。分析显示那:(1 ) 区域在 Qinghai 西藏高原上的雪灾难高风险在 Xinjiang 区域位于 Yecheng 和 Pishan 的县的某些区域;(2 ) 区域在雪中等风险灾难在 Qinghai 西藏高原,和南部的 Qinghai 高原的东南的部分的中央西方的部分在 Gangdise 山和喜马拉雅山脉之间被发现;(3 ) 雪灾难的风险在整个到 30 ‰ ?  ? 的南方的大区域通常是低的 ?????????????  ?? 吗??LIU Fenggui MAO Xufeng ZHANG Yili CHEN Qiong LIU Pei ZHAO Zhilong 2014Journal of Geographical Sciences2014,24,3:13
4Epidermal growth factor receptor (EGFR) T790M mutation identified in plasma indicates failure sites and predicts clinical prognosis in non-small cell lung cancer progression during first-generation tyrosine kinase inhibitor therapy: a prospective observational study显示文摘Introduction:Plasma circulating tumor DNA(ctDNA)is an ideal approach to detecting the epidermal growth factor receptor(EGFR)T790M mutation,which is a major mechanism of resistance to first-generation EGFR-tyrosine kinase inhibitor(TKI)therapy.The present study aimed to explore the association of ctDNA-identified T790M mutation with disease failure sites and clinical prognosis in non-small cell lung cancer(NSCLC)patients.Methods:Patients who progressed on first-generation TKIs were categorized into failure site groups of chest limited(CF),brain limited(BF)and other(OF).Amplification refractory mutation system(ARMS)and droplet digital PCR(ddPCR)were used to identify the T790M mutation in ctDNA.Prognosis was analyzed with Kaplan-Meier methods.Results:Overall concordance between the two methods was 78.3%.According to both ARMS and ddPCR,patients in the OF group had a significantly higher rate of T790M mutation than did patients in the BF and CF groups(P<0.001),and a significantly higher T790M mutation rate was also observed in OF-group patients than in those in the CF and BF groups(P<0.001).AZD9291 was found to be an excellent treatment option and yielded the longest survival for T790M+patients in all groups who had progressed on EGFR-TKIs;for other treatments,the prognosis of T790M−patient subgroups varied.Conclusions:The present study demonstrates that T790M mutation in ctDNA is associated with failure sites for NSCLC patients after EGFR-TKI therapy and indicates that both failure site and T790M mutational status greatly influ-ence treatment selection and prognosis.Shirong Zhang Lucheng Zhu Bing Xia Enguo Chen Qiong Zhao Xiaochen Zhang Xueqin Chen Xufeng Chen Shenglin Ma 2018Cancer Communications2018,38,1:12
5Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism显示文摘Amycolatopsis mediterranei 被用于 rifamycin 的工业规模生产,它在 antimycobacterial 治疗起一个重要作用。作为类 Amycolatopsis 的首先定序的染色体, 236 715 底配对的包括 10 的紧张 U32 的染色体,最大的原核生物的染色体之一到目前为止曾经被定序。不同于在 streptomycetes 发现的线性拓扑学,这个染色体是圆形的,特别地类似于 Saccharopolyspora erythraea 和奴卡氏菌属 farcinica,在发展史和分类代表他们的靠近的关系。尽管在 A 预言了 9 228 编码蛋白质的基因。mediterranei 染色体 S 与那些分享了 orthologs 的最大的数字。erythraea,它被 Streptomyces coelicolor 而非 N 出人意料地跟随。farcinica,显示不同新陈代谢的特征经由改编演变到多样的生态的壁龛。除类似于那的一个核心区域以外在 streptomycetes 普通,有典型核心特征的一个新奇“伪核心”在非核心区域以内被定义,在 21 从 26 基因为第二等的代谢物生产聚类的总数被定位的地方。位于核心的 rifamycin 生合成基因簇为 rifamycin SV 的变换编码细胞色素 P450 酶必需品到 B,由比作 rifamycin 生产 B 紧张 S699 的高度相应的簇揭示了并且进一步由基因互补证实了。A 的 genomic 信息。mediterranei 表明在看起来复杂的规章的机制的控制下面不仅为各种各样的碳来源和无机的氮混合物的广泛的利用而且为新陈代谢的中介的有效 funneling 安排进第二等的抗菌素合成进程的一个新陈代谢的网络。Wei Zhao Yi Zhong Hua Yuan Jin Wang Huajun Zheng Ying Wang Xufeng Cen Feng Xu Jie Bai Xiaobiao Han Gang Lu Yongqiang Zhu Zhihui Shao Han Yan Chen Li Nanqiu Peng Zilong Zhang Yunyi Zhang Wei Lin Yun Fan Zhongjun Qin Yongfei Hu Baoli Zhu Shengyue Wang Xiaoming Ding Guo-Ping Zbao 2010Cell Research2010,20,10:10
6Genome-wide Analysis of Transcriptional Variability in a Large Maize-Teosinte Population显示文摘基因表示规定在控制植物显型和改编起一个重要作用。这里,我们报导对通过 transcriptome 的基因表示变化的一个全面评价大 maize-teosinte 分析试验性的人口。染色体宽的印射识别了 25 ? 660 表示为 17 的量的特点 loci (eQTL )? 311 基因,捕获表示变化的一个崭新的范围。我们发现本地 eQTL 更经常被印射到邻近的基因,显示表示 piggybacking 的一个模式,它因而创造了共同调整的基因簇。在共同调整的基因簇以内的基因趋于有相关功能和分享的染色质修正。远 eQTL 与他们显著地在特定的功能的范畴充实的目标形成了 125 个重要远 eQTL 热点。由集成信息的不同来源,我们为许多新陈代谢的小径识别了通常认为的 trans- 管理者。我们证明 bHLH 抄写因素 R1 和 hexokinase HEX9 可能分别地为 flavonoid 生合成和 glycolysis 充当关键管理者。而且,我们证明驯服或改进显著地影响了全球基因表示,与选择指向的许多基因。特别兴趣,为生合成可能经历了的 benzoxazinoid 的 Bx 基因协调了在玉米和 teosinte 之间的 cis 规章的分叉,并且当玉米与一个不同草食动物社区传播了进适度的环境,使 Bx12 失去活性的 transposon 插入在强壮的选择下面。Xufeng Wang Qiuyue Chen Yaoyao Wu Zachary H. Lemmon Guanghui Xu Cheng Huang Yameng Liang Dingyi Xu Dan Li John F. Doebley Feng Tian 2018Molecular Plant2018,11,3:7
7Scalable microfabrication of three-dimensional porous interconnected graphene scaffolds with carbon spheres for high-performance all carbon-based micro-supercapacitors显示文摘As one of the most important micro energy storage devices(MESDs),graphene-based micro-supercapacitors(G-MSCs)possess the advantages of excellent flexibility,long cycle life,affordability and high reliability.In most cases,constructing three-dimensional(3D)graphene networks is widely utilized to promote the permeation of electrolyte and enhance the utilization of active materials.In this work,conventional freeze-drying process is utilized in the fabrication of G-MSCs to constitute 3D interconnected networks micro-electrodes,and further by regulating the composition of inks,carbon spheres(CSs)at different mass loadings are introduced into the graphene scaffolds to further increase the active sites of the micro-electrodes.The fabricated all carbon-based MSC with the optimal mass loading of CSs(0.406 mg cm^(-2))exhibits a high specific areal capacitance of 17.01mF cm^(-2)at the scan rate of 10mV s^(-1)and a capacitance retention of 93.14%after 10000 cycles at the scan rate of 500 mV s^(-1).The proposed microfabrication process is facile and fully compatible with modern microtechnologies and will be highly suitable for large-scale production and integration.Yiming Chen Minghao Guo Liang He Wei Yang Lin Xu Jiashen Meng Xiaocong Tian Xinyu Ma Qiang Yu Kaichun Yang Xufeng Hong Liqiang Mai 2019Journal of Materiomics2019,5,2:6
8Androgen-deprivation therapy-induced aggressive prostate cancer with neuroendocrine differentiation显示文摘大多数前列腺癌症(PCas ) 作为 acinar 类型被分类(常规) 有包括雄激素受体(AR ) 和前列腺特定的抗原(PSA ) 的表示的钠区别的肿瘤房间镇静的腺癌。在腺癌的每种情况中有也散布的 neuroendocrine (NE ) 房间。NE 房间是 quiesecent,不表示 AR 或 PSA,并且他们的功能仍然保持不清楚。我们证明了那条 IL8-CXCR2-P53 小径提供一个生长禁止的信号并且把 NE 房间放在良性的前列腺和腺癌静止。有趣地,在神经质的治疗,和如此的肿瘤由是的纯 NE 房间组成以后,有腺癌的历史的一些病人与小房间 neuroendocrine 癌(SCNC ) 复发高度 proliferative 并且好攻击,由于 P53 变化和 IL8-CXCR2-P53 小径的 inactivation。SCNC 的发生将多半由于进一步禁止 AR 功能或 intratumoral 雄激素合成的新奇的药的普遍使用增加。阶段 II 试用证明了基于铂的化疗可能为如此的导致治疗的肿瘤是有用的。Julia Lipianskaya Alexa Cohen Clark J Chen Elaine Hsia Jill Squires Zhen Li Yaqun Zhang Wei Li Xufeng Chen Hua Xu Jiaoti Huang 2014Asian Journal of Andrology2014,16,4:6
9Chiral Spirocyclic Phosphoric Acids and Their Growing Applications显示文摘Chiral spirocyclic phosphoric acids(SPAs)are introduced in 2010 and have been versatile catalysts capable of promoting a wide range of asymmetric organocatalytic reactions,such as multi-component reactions,Friedel–Crafts reactions,Pictet–Spengler reactions,Fischer indolizations,cycloaddition reactions,desymmetrization reactions,dearomatization reactions,conjugate addition reactions and rearrangement reactions,etc.Moreover,a diverse range of applications in metal-organic cooperative catalysis,organic photoredox catalysis,total synthesis,materials science and molecular recognition are beautifully illustrated.This account summarizes the past decade's advances in this field and highlights the selected but not comprehensive significant achievements.Xufeng Lin Lei Wang Zhao Han Zhouli Chen 2021Chinese Journal of Chemistry2021,39,4:5
10The size of cell-free mitochondrial DNA in blood is inversely correlated with tumor burden in cancer patients显示文摘Circulating cell-free DNAs(cfDNAs)are fragmented DNA molecules released into the blood by cells.Previous studies have suggested that mitochondria-originated cfDNA fragments(mt-cfDNAs)in cancer patients are more fragmented than those from healthy controls.However,it is still unknown where these short mtcfDNAs originate,and whether the length of mt-cfDNAs can be correlated with tumor burden and cancer progression.In this study,we first performed whole-genome sequencing analysis(WGS)of cfDNAs from a human tumor cell line-xenotransplantation mouse model and found that mt-cfDNAs released from transplanted tumor cells were shorter than the mouse counterpart.We next analyzed blood cfDNA samples from hepatocellular carcinoma and prostate cancer patients and found that mt-cfDNA lengths were inversely related to tumor size as well as the concentration of circulating tumor DNA.Our study suggested that monitoring the size of mt-cfDNAs in cancer patients would be a useful way to estimate tumor burden and cancer progression.Qin An Youjin Hu Qingjiao Li Xufeng Chen Jiaoti Huang Matteo Pellegrini Xianghong Jasmine Zhou Matthew Rettig Guoping Fan 2019Precision Clinical Medicine2019,2,3:4
11第一代酪氨酸激酶抑制剂治疗中发生进展的非小细胞肺癌血浆表皮生长因子受体(EGFR)T790M突变提示了失败部位并预测了临床预后:一项前瞻性观察研究显示文摘背景与目的血浆循环肿瘤DNA(circulating tumor DNA,ctDNA)是检测表皮生长因子受体(epidermal growth factor receptor,EGFR)T790M突变的理想方法。T790M突变是第一代EGFR酪氨酸激酶抑制剂(tyrosine kinase inhibitor,TKI)耐药的主要机制。本研究旨在探讨ctDNA来源的T790M突变与非小细胞肺癌(non-small cell lung cancer,NSCLC)患者疾病失败部位及临床预后的关系。方法第一代TKI治疗发生进展的患者被分为局限胸内进展(chest limited,CF)、局限颅内进展(brain limited,BF)和其他部位进展(other,OF)组。采用扩增阻滞突变系统(amplification refractory mutation system,ARMS)和微滴式数字PCR(droplet digital PCR,ddPCR)对ctDNA中T790M突变进行了检测。采用Kaplan-Meier法分析了预后。结果 2种方法的总体一致性为78.3%。根据ARMS和ddPCR,OF组患者的T790M突变率明显高于BF组和CF组(P <0.001),OF组的T790M突变丰度也明显高于CF组和BF组(P <0.001)。AZD9291是T790M+患者最佳治疗选择,为EGFR-TKI治疗后进展的所有组中T790M+患者提供了最长的生存期;接受其他治疗的T790M-患者亚组的预后各不相同。结论本研究表明ctDNA中T790M突变与NSCLC患者EGFR-TKI治疗失败部位相关,失败部位和T790M突变状态对治疗选择和预后都有很大影响。Shirong Zhang Lucheng Zhu Bing Xia Enguo Chen Qiong Zhao Xiaochen Zhang Xueqin Chen Xufeng Chen Shenglin Ma 2018癌症2018,37,9:4
12Abscisic acid receptors maintain abscisic acid homeostasis by modulating UGT71C5 glycosylation activity显示文摘Uridine diphosphate-glucosyltransferases(UGTs)maintain abscisic acid(ABA)homeostasis in Arabidopsis thaliana by converting ABA to abscisic acid-glucose ester(ABA-GE).UGT71C5 plays an important role in the generation of ABA-GE.Abscisic acid receptors are crucial upstream components of the ABA signaling pathway,but how UGTs and ABA receptors function together to modulate ABA levels is unknown.Here,we demonstrated that the ABA receptors RCAR12/13 and UGT71 C5 maintain ABA homeostasis in Arabidopsis following rehydration under drought stress.Biochemical analyses show that UGT71C5 directly interacted with RCAR8/12/13 in yeast cells,and the interactions between UGT-71C5 and RCAR12/13 were enhanced by ABA treatment.Enzyme activity analysis showed that ABA-GE contents were significantly elevated in the presence of RCAR12 or RCAR13,suggesting that these ABA receptors enhance the activity of UGT71C5.Determination of the content of ABA and ABA-GE in Arabidopsis following rehydration under drought stress revealed that ABA-GE contents were significantly higher in Arabidopsis plants overexpressing RCAR12 and RCAR13 than in nontransformed plants and plants overexpressing RCAR11 following rehydration under drought stress.These observations suggest that RCAR12 and RCAR13 enhance the activity of UGT71C5 to glycosylate excess ABA into ABA-GE following rehydration under drought stress,representing a rapid mechanism for regulating plant growth and development.Yanlin Ma Jing Cao Qiaoqiao Chen Jiahan He Zhibin Liu Jianmei Wang Xufeng Li Yi Yang 2021Journal of Integrative Plant Biology2021,63,3:3
13Rare earth elements and yttrium in ferromanganese deposits from the South China Sea:distribution,composition and resource considerations显示文摘Ferromanganese nodules and crusts contain relatively high concentration of rare earth elements(REE) and yttrium(REY),with a growing interest in exploitation as an alternative to land-based REY resources.On the basis of comprehensive geochemical approach,the abundance and distribution of REY in the ferromanganese nodules from the South China Sea are analyzed.The results indicate that the REY contents in ferromanganese deposits show a clear geographic regularity.Total REY contents range from 69.1×10^(–6) to 2 919.4×10^(–6),with an average value of 1 459.5×10^(–6).Especially,the enrichment rate of Ce content is high,accounting for almost 60% of the total REY.This REE enrichment is controlled mainly by the sorption of ferromanganese oxides and clay minerals in the nodules and crusts.Moreover,the total REY are higher in ferromanganese deposits of hydrogenous origin than of diagenetic origin.Finally,Light REE(LREE) and heavy REE(HREE) oxides of the ferromanganese deposits in the study area can be classified into four grades: non-enriched type,weakly enriched type,enriched type,and extremely enriched type.According to the classification criteria of rare earth resources,the Xisha and Zhongsha platform-central deep basin areas show a great potential for these rare earth metals.ZHONG Yi CHEN Zhong GONZALEZ Francisco Javier ZHENG Xufeng LI Gang LUO Yun MO Aibin XU Antao WANG Shuhong 2018Acta Oceanologica Sinica2018,37,7:3
14Glossy15 Plays an Important Role in the Divergence of the Vegetative Transition between Maize and Its Progenitor, Teosinte显示文摘Dingyi Xu Xufeng Wang Cheng Huang Guanghui Xu Yameng Liang Qiuyue Chen Chenglong Wang Dan Li Jinge Tian Lishuan Wu Yaoyao Wu Li Guo Xuehan Wang Weihao Wu Weiqiang Zhang Xiaohong Yang Feng Tian 2017Molecular Plant2017,10,12:3
15Thermal and luminescent properties of 2 μm emission in thulium-sensitized holmium-doped silicate-germanate glass显示文摘In this paper, we present the luminescent properties of Tm^(3+)∕Ho^(3+)co-doped new glass. A series of silicategermanate glass was prepared by the conventional melt-quenching method. In the Tm^(3+)∕Ho^(3+)co-doped silicategermanate glass, a strong emission of 2 μm originating from the Ho^(3+):~5I_7→~5I_8transition can be observed under conventional 808 nm pumping. The characteristic temperatures, structure, and absorption spectra have been measured. The radiative properties of Ho^(3+)in the prepared glass were calculated. The emission cross section of Ho^(3+)ions transition can reach 4.78 × 10^(-21)cm^2 around 2 μm, and the FWHM is as high as 153 nm. The energy transfer efficiency between Ho^(3+)and Tm^(3+)has a large value(52%), which indicates the Tm^(3+)∕Ho^(3+)co-doped silicategermanate glass is a suitable candidate for the 2 μm laser. Moreover, the energy transfer mechanism between Tm^(3+)and Ho^(3+)ions was investigated.Rong Chen Ying Tian Bingpeng Li Xufeng Jing Junjie Zhang Shiqing Xu Hellmut Eckert Xianghua Zhang 2016Photonics Research2016,4,6:2
16Microstructuring of carbon/tin quantum dots via a novel photolithography and pyrolysis-reduction process显示文摘Xufeng Hong Liang He Xinyu Ma Wei Yang Yiming Chen Lei Zhang Haowu Yan Zhaohuai Li Liqiang Mai 2017Nano Research2017,10,11:2
17Micro-and nano-structured conducting polymeric materials显示文摘Conducting polymeric materials with micro-/ nano-structures have potential applications in fabrication of various optical, electronic, sensing and electrochemical de-vices. This is mainly because these materials not only possess the characteristics of conducting polymers, but also have special functions based on their micro- or nano-structures. In this review, we summarize the recent work on “soft” and “hard” template-guided syntheses of micro-/nano-structured conducting polymers and open up the prospects of the main trends in this field.LU Gewu CHEN Feng'en WU Xufeng QU Liangti ZHANG Jiaxin SHI Gaoquan 2005Chinese Science Bulletin2005,50,16:2
18Preparation and properties of hollow fibre nanofiltration membrane with continuous coffee-ring structure显示文摘Polyamide(PA)hollow fibre composite nanofiltration(NF)membranes with a coffee-ring structure and beneficial properties were prepared by adding graphene oxide(GO)into the interfacial polymerization process.The presentation of the coffee-ring structure was attributed to the heterogeneous,finely dispersed multiphase reaction system and the“coffee-stain”effect of the GO solution.When the piperazine concentration was 0.4 wt-%,the trimesoyl chloride concentration was 0.3 wt-%,and the GO concentration was 0.025 wt-%,the prepared NF membranes showed the best separation properties.The permeate flux was 76 L·m^(−2)·h^(−1),and the rejection rate for MgSO4 was 98.6%at 0.4 MPa.Scanning electron microscopy,atomic force microscopy,and attenuated total reflectance-Fourier transform infrared spectroscopy were used to characterize the chemical structure and morphology of the PA/GO NF membrane.The results showed that GO was successfully entrapped into the PA functional layer.Under neutral operating conditions,the PA/GO membrane showed typical negatively charged NF membrane separation characteristics,and the rejection rate decreased in the order of Na2SO_(4)>MgSO_(4)>MgCl_(2)>NaCl.The PA/GO NF membrane showed better antifouling performance than the PA membrane.Xiuzhen Wei Xufeng Xu Yi Chen Qian Zhang Lu Liu Ruiyuan Yang Jinyuan Chen Bosheng Lv 2021Frontiers of Chemical Science and Engineering2021,15,2:2
19Nano-channel-based physical and chemical synergic regulation for dendrite-free lithium plating显示文摘Uncontrollable dendrite growth resulting from the non-uniform lithium ion(Li^(+))flux and volume expansion in lithium metal(Li)negative electrode leads to rapid performance degradation and serious safety problems of lithium metal batteries.Although N-containing functional groups in carbon materials are reported to be effective to homogenize the Li^(+)flux,the effective interaction distance between lithium ions and N-containing groups should be relatively small(down to nanometer scale)according to the Debye length law.Thus,it is necessary to carefully design the microstructure of N-containing carbon materials to make the most of their roles in regulating the Li^(+)flux.In this work,porous carbon nitride microspheres(PCNMs)with abundant nanopores have been synthesized and utilized to fabricate a uniform lithiophilic coating layer having hybrid pores of both the nano-and micrometer scales on the Cu/Li foil.Physically,the three-dimensional(3D)porous framework is favorable for absorbing volume changes and guiding Li growth.Chemically,this coating layer can render a suitable interaction distance to effectively homogenize the Li^(+)flux and contribute to establishing a robust and stable solid electrolyte interphase(SEI)layer with Li-F,Li-N,and Li-O-rich contents based on the Debye length law.Such a physical-chemical synergic regulation strategy using PCNMs can lead to dendrite-free Li plating,resulting in a low nucleation overpotential and stable Li plating/stripping cycling performance in both the Li||Cu and the Li||Li symmetric cells.Meanwhile,a full cell using the PCNM coated Li foil negative electrode and a LiFePO4 positive electrode has delivered a high capacity retention of~80%after more than 200 cycles at 1 C and achieved a remarkable rate capability.The pouch cell fabricated by pairing the PCNM coated Li foil negative electrode with a NCM 811 positive electrode has retained~73%of the initial capacity after 150 cycles at 0.2 C.Qiang Guo Wei Deng Shengjie Xia Zibo Zhang Fei Zhao Binjie Hu Sasa Zhang Xufeng Zhou George Zheng Chen Zhaoping Liu 2021Nano Research2021,14,10:1
20Clinical efficacy of modified preoperative neoadjuvant chemotherapy in the treatment of locally advanced (stage IB2 to IIB) cervical cancer: A randomized study显示文摘Huijun Chen Chuan Liang Lei Zhang Shuang Huang Xufeng Wu 2008Gynecologic Oncology2008,,:1
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