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| 1 | 动脉自旋标记脑灌注MRI技术规范化应用专家共识显示文摘动脉自旋标记(arterial spin labeling, ASL)是利用血液中水分子作为内源性、可自由扩散示踪剂进行颅脑灌注成像的MRI技术。ASL技术提出至今已有20余年[1],经历了多个发展阶段。随着ASL技术的不断进步,尤其是近年来准连续式ASL (pseudo-continuous ASL, pCASL)序列的应用,其图像质量、成像范围、成像速度有了极大的提高,逐渐受到影像学和神经科学工作者的关注,并越来越多地应用于科研和临床工作。 | 无 | 2016 | 中华放射学杂志2016，50，11： | 100 |
| 2 | 肝癌综合介入治疗的现状显示文摘原发性肝癌恶性程度很高,大多数患者就诊时已无外科手术指征,即使能进行外科手术切除,术后肿瘤复发率亦较高.采用肝动脉插管化疗、栓塞方法(transcatheter arterial chemoembolization,TACE)亦称介入疗法,治疗不能手术切除的肝癌和术后复发的肝癌,取得了良好的效果.介入疗法已被公认为治疗不能手术切除和术后复发肝癌的首选方法,但肝癌介入治疗后复发、转移问题仍末解决,影响了其远期生存率.越来越多的学者认识到对肝癌采用综合介入治疗的必要性和重要性. | 王建华 | 2005 | 中华肝脏病杂志2005，13，10： | 80 |
| 3 | 原发性肝细胞癌经导管肝动脉化疗性栓塞治疗技术操作规范专家共识显示文摘原发性肝细胞癌(hepatocellular carcinoma,HCC,以下简称肝癌)是起源于肝细胞的恶性肿瘤。在中国,85%~90%是在肝炎后肝硬化的基础上发生。肝癌是一种富血供肿瘤,90%以上的血供来源于肝动脉。用加入化疗药物的栓塞剂栓塞肿瘤供血动脉,称经导管的肝动脉化疗性栓塞(transcatheter arterial chemoembolization,TACE)。这种治疗方法一方面阻断肿瘤血供,同时在肿瘤局部聚集高浓度的化疗药物, | | 2011 | 中华放射学杂志2011，45，10： | 65 |
| 4 | Regulation of hepatic blood flow:The hepatic arterial buffer response revisited显示文摘The interest in the liver dates back to ancient times when it was considered to be the seat of life processes. The liver is indeed essential to life,not only due to its complex functions in biosynthesis,metabolism and clearance,but also its dramatic role as the blood volume reservoir. Among parenchymal organs,blood flow to the liver is unique due to the dual supply from the portal vein and the hepatic artery. Knowledge of the mutual communication of both the hepatic artery and the portal vein is essential to understand hepatic physiology and pathophysiology. To distinguish the individual importance of each of these inflows in normal and abnormal states is still a challenging task and the subject of on-going research. A central mechanism that controls and allows constancy of hepatic blood flow is the hepatic arterial buffer response. The current paper reviews the relevance of this intimate hepatic blood flow regulatory system in health and disease. We exclusively focus on the endogenous interrelationship between the hepatic arterial and portal venous inflow circuits in liver resection and transplantation,as well as inflammatory and chronic liver diseases. We do not consider the hepatic microvascular anatomy,as this has been the subject of another recent review. | Christian Eipel Kerstin Abshagen Brigitte Vollmar | 2010 | World Journal of Gastroenterology2010，16，48： | 49 |
| 5 | 颅内动脉夹层的影像学诊断中国专家共识显示文摘颅内动脉夹层(intracranial arterial dissection,IAD)是指各种原因使血液成分通过破损的颅内动脉内膜进入血管壁,导致血管壁间剥离分层形成血肿,或颅内动脉壁内自发性血肿,造成血管狭窄、闭塞或破裂的一种疾病。如果形成瘤样突起,则称为颅内夹层动脉瘤(intracranial dissecting aneurysm,IDA)。 | 无 | 2016 | 中华神经外科杂志2016，32，11： | 49 |
| 6 | Radiofrequency ablation of hepatocellular carcinoma:Current status显示文摘Ablation therapy is one of the best curative treatment options for malignant liver tumors,and can be an alternative to resection.Radiofrequency ablation(RFA) of primary and secondary liver cancers can be performed safely using percutaneous,laparoscopic,or open surgical techniques,and RFA has markedly changed the treatment strategy for small hepatocellular carcinoma(HCC).Percutaneous RFA can achieve the same overall and disease-free survival as surgical resection for patients with small HCC.The use of a laparoscopic or open approach allows repeated placements of RFA electrodes at multiple sites to ablate larger tumors.RFA combined with transcatheter arterial chemoembolization will make the treatment of larger tumors a clinically viable treatment alternative.However,an accurate evaluation of treatment response is very important to secure successful RFA therapy.Since a sufficient safety margin(at least 0.5 cm) can prevent local tumor recurrences,an accurate evaluation of treatment response is very important to secure successful RFA therapy.To minimize complications of RFA,clinicians should be familiar with the imaging features of each type of complication.Appropriate management of complications is essential for successful RFA treatment. | Yasunori Minami Masatoshi Kudo | 2010 | World Journal of Radiology2010，2，11： | 40 |
| 7 | 动脉粥样硬化性肾动脉狭窄诊治中国专家建议(2010)显示文摘动脉粥样硬化性肾动脉狭窄(atherosclerotic renal arterial stenosis,ARAS)是指由于动脉粥样硬化引起的肾动脉管腔狭窄。目前学者们普遍认为,当局限性管腔狭窄程度≥50%时,才是有临床意义的肾动脉狭窄。ARAS可进展至严重的肾动脉狭窄乃至肾动脉闭塞,是缺血性肾病、顽固性心绞痛和心力衰竭的主要病因之一。研究结果表明,ARAS是近年来老年患者终末期肾病(end stage renal disease,ESRD)病因中增长最快的病变。 | 无 | 2010 | 中华老年医学杂志2010，29，4： | 40 |
| 8 | 预见性护理在减少肝癌患者动脉介入化疗栓塞术并发症中的应用效果评价显示文摘肝动脉化疗栓塞术(transcatheter arterial chemoembolization,TACE)是目前中晚期肝细胞癌治疗的首选方法,有临床资料显示,TACE能有效延长患者2年[1]的存活率.但是在多次行TACE术后,容易增加肝脏负担,同时由于形成新生血管,增加了肿瘤转移的可能性,因此,每次治疗要提高治疗的有效性.通过多年的介入护理实践发现,肝癌TACE术后患者具有多种并发症,通过有效的护理干预,在增加治疗有效性、保障护理顺利进行、减少并发症方面具有重要意义.预见性护理即超前护理,是现代护理发展的新理念,是针对患者的危险因素采取针对性的预防措施,通过采取预见性护理,能够降低疾病的恶化率,在预防危重症并发症的过程中已愈来愈受到重视[2].预见性护理的主要方法是对患者进行评估,根据病情确定护理要点,并采取相应的预防措施.我科对肝癌行TACE术患者采取预见性护理措施,取得了良好的护理效果,现报道如下. | 孙敬梅 吕英慧 白丽华 | 2014 | 中国实用护理杂志2014，30，14： | 36 |
| 9 | 双胎妊娠临床处理指南(第二部分)双胎妊娠并发症的诊治显示文摘“双胎妊娠临床处理指南(第二部分)”主要针对双胎妊娠并发症的诊断和处理,包括双绒毛膜性双胎并发症,如双胎生长不一致、一胎结构异常、一胎胎死宫内;单绒毛膜性双胎特殊并发症,如双胎输血综合征(twin-to-twin transfusion syndrome, TTTS)、选择性胎儿宫内生长受限(selective intrauterine growth restriction,sIUGR)、双胎反向动脉灌注序列(twin reversed arterial perfusion sequence,TRAPS)、双胎贫血-多血序列征(twin anemia polycythemia sequence,TAPS)等。由于双胎妊娠并发症,尤其是单绒毛膜性双胎并发症整体发病率较低,缺少大样本的随机对照研究,很多相关的临床研究结论来自于专家共识及经验性结论,对某些并发症的处理仍存在较大的争议。本指南所推荐内容来自于迄今为止所发表的最高级别的文献证据,需要随着临床实践的发展进行不断更新和完善。 | | 2015 | 中华妇产科杂志2015，50，9： | 39 |
| 10 | 子宫肌瘤血管性介入治疗的新进展显示文摘 | 刘萍 陈春林 | 2005 | 实用妇产科杂志2005，21，4： | 31 |
| 11 | 原发性肝癌TACE治疗进展显示文摘原发性肝癌是我国常见的恶性肿瘤之一,目前,最有效且有可能根治的方法仍为手术切除。但大部分病例被发现时已属中晚期,已失去手术切除的治疗机会。经导管动脉化疗栓塞术(transcatheter arterial chemoembolization, TACE)是中晚期肝癌的主要治疗方式之一,可以有效延长患者生存期、改善患者生活质量,是目前公认的肝癌非手术治疗的首选治疗方法。本文就原发性肝癌的TACE治疗及其进展综述如下。 | 兰春虎 王常友 | 2009 | 当代医学2009，15，23： | 31 |
| 12 | 小儿先天性心脏病相关性肺高压诊断和治疗(专家共识)显示文摘前言
肺高压(pulmonary hypertension,PH)是指在海平面安静呼吸时由右心导管检查测得的肺动脉平均压(meanpul—monary arterial pressure,mPAP)≥25mmHg。肺动脉高压(pulmonary arterial hypertension,PAH)是指孤立的肺动脉压力增高,而肺静脉压力正常, | | 2011 | 中华小儿外科杂志2011，32，4： | 34 |
| 13 | Treatment of hepatocellular carcinoma with portal venous tumor thrombosis: A comprehensive review显示文摘The natural history of hepatocellular carcinoma(HCC)with portal vein tumor thrombosis(PVTT)is dismal(approximately 2-4 mo),and PVTT is reportedly found in 10%-40%of HCC patients at diagnosis.According to the Barcelona Clinic Liver Cancer(BCLC)Staging System(which is the most widely adopted HCC management guideline),sorafenib is the standard of care for advanced HCC(i.e.,BCLC stage C)and the presence of PVTT is included in this category.However,sorafenib treatment only marginally prolongs patient survival and,notably,its therapeutic efficacy is reduced in patients with PVTT.In this context,there have been diverse efforts to develop alternatives to current standard systemic chemotherapies or combination treatment options.To date,many studies on transarterial chemoembolization,3-dimensional conformal radiotherapy,hepatic arterial chemotherapy,and transarterial radioembolization report better overall survival than sorafenib therapy alone,but their outcomes need to be verified in future prospective,randomized controlled studies in order to be incorporated into current treatment guidelines.Additionally,combination strategies have been applied to treat HCC patients with PVTT,with the hope that the possible synergistic actions among different treatment modalities would provide promising results.This narrative review describes the current status of the management options for HCC with PVTT,with a focus on overall survival. | Kichang Han Jin Hyoung Kim Gi-Young Ko Dong Il Gwon Kyu-Bo Sung | 2016 | World Journal of Gastroenterology2016，22，1： | 29 |
| 14 | 2020年中国急性肠系膜缺血诊断与治疗专家共识显示文摘急性肠系膜缺血(acute mesenteric ischemia, AMI)常被定义为小肠部分血液供应的突然中断,引起的局部缺血、细胞损伤和肠道病变。如果未经及时治疗,该过程将迅速进展为危及生命的肠坏死。AMI有非闭塞性(acute non-occlusive mesenteric ischemia, NOMI)和闭塞性两种类型,闭塞性肠系膜缺血又可进一步细分为肠系膜动脉栓塞(acute mesenteric artery embolism, EAMI),肠系膜动脉血栓形成(acute mesenteric arterial thrombosis, TAMI)及肠系膜静脉血栓形成(mesenteric venous thrombosis, VAMI)。该病总体发病率较低,但在全部急诊就诊患者中,其比例仍能达到0.09%~0.2% 。 | 无 金红旭 赵晓东 吕传柱 于学忠 戴晶 姜宏 | 2020 | 中华急诊医学杂志2020，29，10： | 30 |
| 15 | Association between vascular endothelial growth factor and metastasis after transcatheter arterial chemoembolization in patients with hepatocellular carcinoma显示文摘BACKGROUND: Hypoxia up-regulates vascular endothelialgrowth factor (VEGF) and stimulates the growth of hepa-tocellular carcinoma (HCC) cells. This study was designedto investigate the association between changes in plasmaVEGF levels after transcatheter arterial chemoembolization(TACE) and HCC progression, especially in relation tometastasis.METHODS: Plasma VEGF levels were measured by quati-tative sandwich enzyme-linked immunosorbent assay(ELISA R&D system). Plasma VEGF levels were measuredbefore, 3 days and 4 weeks after TACE in 30 patients withHCC. The development of metastasis was evaluated at theend of the third month after TACE.RESULTS: The plasma VEGF levels of the 30 patients withHCC were 154.47±90.17 pg/ml. The total plasma VEGFlevels after TACE increased compared with their basal levels(P<0.05), and the plasma VEGF levels had a tendency toincrease in patients with heterogenous uptake of iodizdoiland portal vein thrombosis. Follow-up for six monthsshowed metastatic foci in 20 patients (74%) with increasedplasma VEGF, but none of the patients with decreased plas-ma VEGF developed metastasis.CONCLUSION: Increased plasma VEGF expression is asso-ciated with the development of metastasis in HCC after TA-CE. | Zheng-Ping Xiong, Shu-Ren Yang, Zhao-Yu Liang, En-Hua Xiao, Xiao-Ping Yu,Shen-Ke Zhou and Zi-Shu Zhang, Department of Radiology , Hunan Provincial TumorHospital. Changsha 410006, China Department of Radiology, Xiangya Second Hospital of Central South Uni-versity, Changsha 410011, China | 2004 | Hepatobiliary & Pancreatic Diseases International2004，3，3： | 27 |
| 16 | Risk factors associated with the development of ischemic colitis显示文摘AIM:To ascertain the role of cardiovascular risk factors,cardiovascular diseases,standard treatments and other diseases in the development of ischemic colitis(IC).METHODS:A retrospective,case-control study was designed,using matched data and covering 161 incident cases of IC who required admission to our hospital from 1998 through 2003.IC was diagnosed on the basis of endoscopic findings and diagnostic or compatible his-tology.Controls were randomly chosen from a cohort of patients who were admitted in the same period and required a colonoscopy,excluding those with diagnosis of colitis.Cases were matched with controls(ratio 1:2),by age and sex.A conditional logistic regression was performed.RESULTS:A total of 483 patients(161 cases,322 con-trols)were included;mean age 75.67±10.03 years,55.9%women.The principal indications for colonos-copy in the control group were lower gastrointestinal hemorrhage(35.4%),anemia(33.9%),abdominal pain(19.9%)and diarrhea(9.6%).The endoscopic findings in this group were hemorrhoids(25.5%),diverticular disease(30.4%),polyps(19.9%)and colorectal cancer(10.2%).The following variables were associated with IC in the univariate analysis:arterial hypertension(P= 0.033);dyslipidemia(P<0.001);diabetes mellitus(P =0.025);peripheral arterial disease(P=0.004);heart failure(P=0.026);treatment with hypotensive drugs(P=0.023);angiotensin-converting enzyme inhibitors;(P=0.018);calcium channel antagonists(P=0.028);and acetylsalicylic acid(ASA)(P<0.001).Finally,the following variables were independently associated with the development of IC:diabetes mellitus[odds ratio(OR)1.76,95%confidence interval(CI):1.001-3.077,P=0.046];dyslipidemia(OR 2.12,95%CI:1.26-3.57,P=0.004);heart failure(OR 3.17,95%CI:1.31-7.68,P=0.01);peripheral arterial disease(OR 4.1,95%CI:1.32-12.72,P=0.015);treatment with digoxin(digitalis)(OR 0.27,95%CI:0.084-0.857,P=0.026);and ASA(OR 1.97,95%CI:1.16-3.36,P=0.012).CONCLUSION:The development of an episode of IC was independently associated with diabetes,dyslipid-emia,presence of heart failure,peripheral arterial dis-ease and treatment with digoxin or ASA. | Joaquín Cubiella Fernández Luisa Núez Calvo Elvira González Vázquez Maria Jesús García García Maria Teresa Alves Pérez Isabel Martínez Silva Javier Fernández Seara | 2010 | World Journal of Gastroenterology2010，16，36： | 27 |
| 17 | Transcatheter arterial chemoembolization followed by immediate radiofrequency ablation for large solitary hepatocellular carcinomas显示文摘AIM: To assess the technical safety and efficacy of transcatheter arterial chemoembolization (TACE) combined with immediate radiofrequency ablation (RFA) for large hepatocellular carcinomas (HCC) (maximum diameter ≥ 5 cm). METHODS: Individual lesions in 18 patients with HCCs (mean maximum diameter: 7.5 cm; range: 5.1-15.5 cm) were treated by TACE combined with percutaneous RFA between January 2010 and June 2012. All of the patients had previously undergone one to four cycles of TACE treatment. Regular imaging and laboratory tests were performed to evaluate the rate of technical success, technique-related complications, local-regional tumor responses, recurrence-free survival time and survival rate after treatment.RESULTS: Technical success was achieved for all 18 visible HCCs. Complete response (CR) was observed in 17 cases, and partial response was observed in 1 case 1 mo after intervention. The CR rate was 94.4%. Local tumors were mainly characterized by coagulative necrosis. During follow-up (2-29 mo), the mean recurrencefree survival time was 16.8 ± 4.0 mo in 17 cases of CR. The estimated overall survival rate at 6, 12, and 18 mo was 100%. No major complications were observed. Levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in the blood of 17 patients transiently increased on the third day after treatment (ALT 200.4 ± 63.4 U/L vs 24.7 ± 9.3 U/L, P < 0.05; AST 228.1 ± 25.4 U/L vs 32.7 ± 6.8 U/L, P < 0.05). Severe pain occurred in three patients, which was controlled with morphine and fentanyl. CONCLUSION: TACE combined with immediate RFA is a safe and effective treatment for large solitary HCCs. Severe pain is a major side effect, but can be controlled by morphine. | Zhi-Jun Wang Mao-Qiang Wang Feng Duan Peng Song Feng-Yong Liu Zhong-Fei Chang Yan Wang Jie-Yu Yan Kai Li | 2013 | World Journal of Gastroenterology2013，19，26： | 24 |
| 18 | TACE联合其他手段治疗肝癌发展现状显示文摘 | 张金山 | 2008 | 中国介入影像与治疗学2008，5，2： | 24 |
| 19 | Arterial spin labeling in neuroimaging显示文摘Arterial spin labeling(ASL) is a magnetic resonance imaging technique for measuring tissue perfusion using a freely diffusible intrinsic tracer.As compared with other perfusion techniques,ASL offers several advantages and is now available for routine clinical practice in many institutions.Its noninvasive nature and ability to quantitatively measure tissue perfusion make ASL ideal for research and clinical studies.Recent technical advances have increased its sensitivity and also extended its potential applications.This review focuses on some basic knowledge of ASL perfusion,emerging techniques and clinical applications in neuroimaging. | Sasitorn Petcharunpaisan Joana Ramalho Mauricio Castillo | 2010 | World Journal of Radiology2010，2，10： | 23 |
| 20 | 下肢动脉硬化闭塞症的治疗进展显示文摘下肢动脉硬化闭塞症( arteriosclerosis obliterans , ASO)是在动脉粥样硬化基础上发生的下肢动脉闭塞性疾病,是外周动脉疾病( peripheral arterial disease, PAD)的重要组成部分,也是造成下肢缺血的主要原因,可导致间歇性跛行、静息痛、肢端溃疡和肢体坏疽,且该病多合并心脑血管疾病,治疗风险大,致残率及致死率高。随着人类生活水平的提高和老龄化的趋势,下肢动脉硬化闭塞症的发生率逐年上升,且随年龄的增长而增加,70岁以上人群患病率达到15%~33.8%[1,2]。对于PAD的治疗,目前有较多的方法。选择恰当有效的治疗方法,可以减少致残率、致死率,对于改善患者生存质量意义重大。现将该病的治疗方法综述如下。 | 庄金满 李选 | 2014 | 中国微创外科杂志2014，14，9： | 23 |
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