Morphological study on colonic pathology in ulcerative colitis treated by moxibustion

查看全文 作　　者：Huan Gan [1]Wu;Li Bin [1]Zhou;Da Ren [2]Shi;Shi Min [1]Liu;Hui Rong [1]Liu;Bi Meng [3]Zhang;Han Ping [1]Chen;Lin Shan [1]Zhang

机构地区：[1]Shanghai Institute of Acupuncture-Moxibustion and Meridians,Shanghai 200030,China;[2]Tumor Hospital,Shanghai Medical University,Shanghai 200032,China;[3]Zhejiang Traditional Chinese Medicine College,Hangzhou 310009,Zhejiang Province,China

出　　处：《World Journal of Gastroenterology》索引2000年第6卷第6期,共5页

基　　金：the National Science Foudation of China,No.39670899.39970922 摘　　要：AIM To observe the therapeutic effect ofmoxibustion on ulcerative colitis and itsinfluence on the colonic mucosal morphology.METHODS Forty-six patients with ulcerativecolitis were randomly divided into themoxibustion with herbal medicine underneathgroup and the western medicine group.Thirtypatients were treated with the abovemoxibustion and 16 patients with Salicylayefapyridine(SASP).The colonic mucosa of 13patients in the moxibustion group was observedby colonoscopy before and after the treatment.Mucin was also analyzed by H.E and AB-PASstaining.RESULTS Seventeen patients were clinicallycured,12 were improved and 1 unchanged in themoxibustion group.In the control group,5patients were clinically cured,7 improved and 4unchanged.Thirteen patients with active UCwere taken as the subjects for histopathologicanalysis in this study.The colonic mucosallesions were remarkably improved and thecharacteristic of the mucin also changed.Inmost sections,the chronic inflammation ofmucosa was geatly ameliorated(P<0.01).Theinflammatory cell infiltratation much decreased and neutrophils,disapeared in most sections(P<0.001).The goblet cells significantlyincreased(P<0.001);crypt paracrypt abscessor mucosal ulceration was seen(P<0.001).CONCLUSION The rate of cure of ulcerative colitis by moxibustion with herbal medicine beneath is superior to that by SASP. This sort of moxibustion can effectively improve the colonic mucosal lesions and restore the proportion of mucoprotein to near normal. 关键词：COLITIS ulcerative/therapy MOXIBUSTION intestinal MUCOSA morphological study

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Morphological study on colonic pathology in ulcerative colitis treated by moxibustion

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