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1Accuracy of clinical diagnosis of idiopathic Parkinson's disease:a clinicopathologic study of 100 cases显示文摘Hughes A J Daniel SE Kilford L 1992J Neurol Neurosurg Psychiatry1992,55,3:10
2Safety and efficacy of stent-assisted coiling for acutely ruptured wide-necked intracranial aneurysms:comparison of LVIS stents with laser-cut stents显示文摘Background:To compare the safety and efficacy of LVIS stent-assisted coiling with those of laser-cut stent-assisted coiling for the treatment of acutely ruptured wide-necked intracranial aneurysms.Methods:Patients with acutely ruptured wide-necked intracranial aneurysms treated with LVIS stent-assisted coiling(LVIS stent group)and laser-cut stent-assisted coiling(laser-cut stent group)were retrospectively reviewed from January 2014 to December 2017.Propensity score matching was used to adjust for potential differences in age,sex,aneurysm location,aneurysm size,neck width,Hunt-Hess grade,and modified Fisher grade.Perioperative procedure-related complications and clinical and angiographic follow-up outcomes were compared.Univariate and multivariate analyses were performed to determine the associations between procedure-related complications and potential risk factors.Results:A total of 142 patients who underwent LVIS stent-assisted coiling and 93 patients who underwent laser-cut stent-assisted coiling were enrolled after 1:2 propensity score matching.The angiographic follow-up outcomes showed that the LVIS stent group had a slightly higher complete occlusion rate and lower recurrence rate than the laser-cut stent group(92.7%vs 80.6%;3.7%vs 9.7%,P=0.078).The clinical outcomes at discharge and follow-up between the two groups demonstrated no significant differences(P=0.495 and P=0.875,respectively).The rates of intraprocedural thrombosis,postprocedural thrombosis,postoperative early rebleeding,and procedure-related death were 0.7%(1/142),1.4%(2/142),2.8%(4/142),and 2.1%(3/142)in the LVIS stent group,respectively,and 4.3%(4/93),2.2%(2/93),1.1%(1/93),and 3.2%(3/93)in the laser-cut stent group,respectively(P=0.082,0.649,0.651,and 0.683).Nevertheless,the rates of overall procedure-related complications and intraprocedural rupture in the LVIS stent group were significantly lower than those in the laser-cut stent group(5.6%vs 14.0%,P=0.028;0.7%vs 6.5%,P=0.016).Multivariate analysis showed that laser-cut stent-assisted coiling was an independent predictor for overall procedurerelated complications(OR=2.727,P=0.037);a history of diabetes(OR=7.275,P=0.027)and other cerebrovascular diseases(OR=8.083,P=0.022)were independent predictors for ischemic complications,whereas none of the factors were predictors for hemorrhagic complications.Conclusions:Compared with laser-cut stent-assisted coiling,LVIS stent-assisted coiling for the treatment of acutely ruptured wide-necked intracranial aneurysms could reduce the rates of overall procedure-related complications and intraprocedural rupture.Gaici Xue Qiao Zuo Xiaoxi Zhang Haishuang Tang Rui Zhao Qiang Li Yibin Fang Pengfei Yang Bo Hong Yi Xu Qinghai Huang Jianmin Liu 2021Chinese Neurosurgical Journal2021,7,2:8
3Quality improvement of nursing on patients with complex cerebral arteriovenous malformation undergoing hybrid surgery:a prospective single-center study显示文摘Background:We sought to explore an optimal clinical nursing mode following a hybrid surgery for cerebral arteriovenous malformation.Methods:Patients with complex cerebral arteriovenous malformations seen in our neurosurgery department from January 2016 to December 2017 were prospectively enrolled.The hybrid surgery protocol included“angiographic diagnosis,surgical resection,and intraoperative angiographic evaluation”and“angiographic diagnosis and embolization,surgical resection,and intraoperative angiographic evaluation”.The patients were randomly stratified into intensive care group and routine care group.After surgery,intensive or routine care was provided,and the prognosis of patients was evaluated,with a subsequent comparative analysis.Results:A total of 109 cases were divided into the routine nursing group(n=54 cases)and intensive nursing group(n=55 cases).There were no significant differences between the two groups in baseline data before surgery.Postoperative lung infection in the intensive nursing group was significantly less frequent than those in the routine nursing group(5.5%vs.18.5%,P=0.039)with pulmonary infection and lower extremity venous thrombosis(5.5%vs.24.1%,P=0.006).The average hospital stay in the intensive nursing group was 14.4±5.78 days,which was significantly lower than that in the routine nursing group(19.3±6.38 days,P=0.013).At 3 months’follow-up after surgery,the Generic Quality of Life Inventory-74(GQOLI-74)dimension score and GQOLI-74 total score in the enhanced group were significantly better than those in the routine nursing group(P=0.017 and 0.023,respectively).Conclusions:Intensive postoperative nursing can improve the safety of patients after hybrid surgery,reduce the postoperative complications and the average length of hospital stay,and improve the quality of life of patients.Dong-Hong Zhao Rui Xue Xiao-Rong Sun 2021Chinese Neurosurgical Journal2021,7,3:4
4Glioblastoma vaccine tumor therapy research progress显示文摘Glioblastoma(GBM)is the most common primary malignancy of the central nervous system in adults.The prognosis for late-stage glioblastoma(World Health Organization grade IV astrocytic glioma)is very poor.Novel treatment options are sought after and evaluated by clinicians and researchers,and remarkable advances have been made in surgical techniques,radiotherapy,and chemotherapy.However,the treatment of glioblastoma remains extremely difficult and it can extend the lives of patients by only a few months.There has been notable progress in the field of immunotherapy,particularly with the use of tumor vaccines,for treating glioblastoma;especially peptide vaccines and cell-based vaccines such as dendritic cell vaccines and tumor cell vaccines.However,the results of the current clinical trials for vaccination are not satisfactory.This article reviews the progress in the development of vaccines for glioblastoma.Tong Zhao Chunwang Li Hongliang Ge Yuanxiang Lin Dezhi Kang 2022Chinese Neurosurgical Journal2022,8,2:3
5Diagnosis, treatment, and misdiagnosis analysis of 28 cases of central nervous system echinococcosis显示文摘Background:To explore central nervous system(CNS)involvement in this disease,from the perspectives of diagnosis,treatment,and misdiagnosis Methods:Twenty-eight patients with CNS echinococcosis were included in this retrospective study,including 18 males(64.3%)and 10(35.7%)females.The average age of all the patients were 23.5 years(ranged 4–60 years).Twenty-three(23)patients(82.1%)received the first surgical resection in our hospital.Five(5)patients(17.9%)gave up surgical treatment for multiple-organ hydatidosis and previous surgery history at other hospitals,and albendazole was applied for a long-term(3–6 months)adjunct therapy for the 5 patients.The average follow-up time was 8 years.Results:For the 28 patients,23 cases received surgical treatments,and the diagnosis was confirmed by pathological examinations.The diagnosis of 4 cases of brain echinococcosis and 2 cases of spinal cord echinococcosis could not be confirmed,resulting in a misdiagnosis rate of 21.4%(6/28).For the pathological examination,a total of 17 cases were infected with Echinococcus granulosus(including 2 cases of spinal cord echinococcosis),and 6 cases were infected with Echinococcus alveolaris.Conclusion:The diagnosis should be specifically considered in endemic regions.The clinical features of CNS hydatidosis were intracranial space-occupying lesions.For the treatment,the surgical removal of cysts should be necessary.In addition,the adjuvant therapy with drug and intraoperative prophylaxis is also suggested.The misdiagnosis may have resulted from atypical clinical features and radiographic manifestations,as well as the accuracy of hydatid immunologic test.Guojia Du Yandong Li Pan Wu Xin Wang Riqing Su Yandong Fan Dangmurenjiafu Geng 2021Chinese Neurosurgical Journal2021,7,4:3
6Risk factors for the incidence of apoplexy in pituitary adenoma: a single-center study from southwestern China显示文摘Background:Although the incidence and clinical manifestations of pituitary apoplexy were reported by a few researches,the results are not consistent.This study aimed to explore the risk factors associated with an incidence of apoplexy in pituitary adenomas.Methods:The clinical information of 843 patients with pituitary adenoma from the Department of Neurological Surgery,1st Affiliated Hospital of Kunming Medical University,was reviewed.The incidence,clinical manifestation,and potential risk factors for pituitary apoplexy were analyzed by a case-control study.Results:In total,121 patients(14.4%)with macroadenoma were suffered from pituitary apoplexy.Headache,vomiting,and visual impairment are the top 3 symptoms for the pituitary apoplexy.Logistic regression results showed that the hypertension(hypertension vs non-hypertension OR=2.765,95%CI:1.41~5.416),tumor type(negative staining vs.positive staining,OR=1.501,95%CI:1.248~5.235),and tumor size(diameter>2 cm vs.diameter≤2 cm,OR=3.952,95%CI:2.211~7.053)are independent factors associated with pituitary apoplexy.Conclusion:Our results indicate that the risk factors for the incidence of pituitary apoplexy depend mainly on properties of the tumor itself(tumor size and pathologic type)and the blood pressure of patients.Yao Li Yuan Qian Yisheng Qiao Xiaoxiang Chen Jiaotian Xu Chao Zhang Wei Wang Junjun Li Xingli Deng 2020Chinese Neurosurgical Journal2020,6,4:3
7Hydrodynamic mechanism of syringomyelia:its relation to myelocele显示文摘Gardner WJ 1965J Neurol Neurosurg Psychiatry1965,28,:2
8Protein kinase inhibition by fasudil hydrochloride promotes neurological recovery after spinal cord injury in rats显示文摘Masahito Hara Masakazu Takayasu Kazuhiko Watanabe 2000J Neurosurg (Spine 1)2000,93,:2
9Experimental intracerebral mass: time-ralated effects on local cerebral blood flow显示文摘Kingman T A Mendelow A D Graham D I 1987J Neurosurg1987,,67:2
10Relationship between visual evoked potentials and intracranial pressure显示文摘York DH Pulliam MW Rosenfeld JG 1981J Neurosurg1981,55,:2
11Reconstruction clipping of ruptured anterior circulation aneurysms via supraorbital lateral keyhole approach显示文摘Background:Intracranial aneurysm(IA)is a serious disease.Analyze and review the cases of anterior circulation ruptured IA by supraorbital lateral keyhole approach,and summarize the experiences of this approach.Methods:Retrospective analysis of 16 cases of ruptured anterior circulation IA in our department from January 2019 to June 2020,CT angiography(CTA)was performed before operation.Analyzing the IA’s parameters by 3D-CT reconstruction.The IA was clipped by supraorbital lateral keyhole approach combined with the 3D-skull reconstruction.Extraventricular drainage was performed before craniotomy.Intraoperative neurophysiological monitoring was performed during the operation.After operation,fluorescein angiography and vascular ultrasound were performed to check the clipping effect.Intracranial pressure monitor was performed postoperatively.CTA was reexamined one week after operation.The modified Rankin Scale(MRS)was performed 6 months after operation.Results:There were 7 males(43.8%)and 9 females(56.2%),and the average age is 52.31±11.12 years old.Among them,11 patients(68.8%)were anterior communicating artery aneurysms and 5(31.2%)were middle cerebral artery aneurysms.All patients were out of hospital within 10 days without any death,without cerebral infarction,cerebrospinal fluid leakage and neurological impairments.About mRS score,after 6 months follow-up,8 cases(50%)had 0 point,4 cases(25%)had 1 point,and 4 cases(25%)had 2 points.Conclusions:For ruptured anterior circulation IA,the supraorbital lateral keyhole approach combined with ventricular drainage,intraoperative electrophysiological monitoring,and intraoperative vascular ultrasound is a safe and minimally invasive treatment.The application of reconstruction clipping can reconstruct the diameter of parent vessel and reduce the recurrence rate of IA.Yuzhang Wu Yan Zhao Shengping Yu Fan Li Shifei Cai Chao Peng Zhen Wang Yifan Yang Bangyue Wang Xinyu Yang 2022Chinese Neurosurgical Journal2022,8,2:2
12Treatment of intracranial gliomas with bone marrow- derived dendritic cells pulsed with tumor antigens显示文摘Linda M Liau MD Keith L 1999J Neurosurg1999,90,6:2
13Control of temporal lobe epilepsy following en bloc resection of low-grade tumors显示文摘Peter JK Minal H Ivan J 1993J Neurosurg1993,78,:2
14Calcitonin gene-related peptide-LI in SAH in man signs of activation of the trigemino cerebrovascular 显示文摘Juul R Edvinsson L Jisrole S 1990Br J Neurosurg1990,4,3:2
15A multicenter prospective randomized controlled trial of the efficacy of mild hypothermia or severely head injured patients with low intracranial pressure显示文摘Shiozaki T Hayakata T Tanoda M 2001J Neurosurg2001,94,:2
16Radiological assessment of hydrocephalus: new theories and implications for therapy显示文摘Dan Greitz 2004Neurosurgical Review2004,,3:2
17Apoptosis Occurs after Cerebral Contusions in Humans显示文摘Ng Ivan Yeo Tseng-Tsai Tang Wen-Ying 2000Neurosurg2000,46,4:2
18Sympathetic skin response:a method of assessing unmyelinated axon dysfunction in peripheral neuropathies显示文摘Shahani BT Halperin JJ Boulu P 1984J Neurol Neurosurg Psychiatry1984,47,5:2
19Gamma knife radiosurgery for pituitary adenomas显示文摘Izawa M Hayashi M Nakay K 2000J Neurosurg2000,93,3:2
20Disseminated intravascular coagulation associated with massive brain injury显示文摘Keimowitz R M Annis B L 1973J Neurosurg1973,39,2:2
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