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| 1 | Cancer immunotherapy: a brief review of the history, possibilities, and challenges ahead显示文摘The knowledge that the body possesses natural defenses to combat cancer existed long before the modern period,with multiple anecdotal reports of tumors miraculously disappearing,sometimes spontaneously or after a febrile or infectious episode.Spontaneous tumor regression of untreated malignant tumors is currently a well-accepted albeit rare phenomenon,and it is recognized that immunosuppression is associated with a higher cancer risk.The treatment of bladder carcinoma by intravesical administration of live attenuated Bacillus Calmette-Guérin bacteria was shown to be very effective in 1976 and is now standard treatment.Effective immunity against cancer involves complex interactions between the tumor,the host,and the environment.Cancer immunotherapy uses various strategies to augment tumor immunity and represents a paradigm shift in treating cancer,since attention has become more focused on the“biologic passport”of the individual tumor rather than the site of origin of the tumor.The different types of cancer immunotherapies discussed here include biologic modifiers,such as cytokines and vaccines,adoptive cell therapies,oncolytic viruses,and antibodies against immune checkpoint inhibitors,such as the co-inhibitory T-cell receptor PD-1 and one of its ligands,programmed death-ligand 1. | Stanley J.Oiseth Mohamed S.Aziz | 2017 | Journal of Cancer Metastasis and Treatment2017,3,1: | 4 |
| 2 | Systemic treatment of advanced pancreatic cancer显示文摘 | Volker Heinemann Michael Haas Stefan Boeck | 2011 | Cancer Treatment Reviews2011,,7: | 3 |
| 3 | Treatment of hepatocellular carcinoma显示文摘 | Jonathan M. Schwartz MD John M. Ham MD | 2003 | Current Treatment Options in Gastroenterology2003,,6: | 3 |
| 4 | Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR显示文摘 | Volker Heinemann Sebastian Stintzing Thomas Kirchner Stefan Boeck Andreas Jung | 2008 | Cancer Treatment Reviews2008,,3: | 3 |
| 5 | Biologic therapies in the metastatic colorectal cancer treatment continuum – Applying current evidence to clinical practice显示文摘 | Marc Peeters Timothy Price | 2011 | Cancer Treatment Reviews2011,,5: | 3 |
| 6 | Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors显示文摘 | Noel Weidner | 1995 | Breast Cancer Research and Treatment1995,,2: | 3 |
| 7 | The systemic inflammation-based Glasgow Prognostic Score: A decade of experience in patients with cancer显示文摘 | Donald C. McMillan | 2012 | Cancer Treatment Reviews2012,,: | 3 |
| 8 | Role of the microenvironment in hepatocellular carcinoma development and progression显示文摘 | Sheng-Di Wu Yu-Shui Ma Ying Fang Li-Li Liu Da Fu Xi-Zhong Shen | 2011 | Cancer Treatment Reviews2011,,3: | 3 |
| 9 | Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): A literature review显示文摘 | Kiran Gupta Jeffrey D. Miller Jim Z. Li Mason W. Russell Claudie Charbonneau | 2007 | Cancer Treatment Reviews2007,,3: | 3 |
| 10 | Chemopreventive effects of dietary phytochemicals against cancer invasion and metastasis: Phenolic acids, monophenol, polyphenol, and their derivatives显示文摘 | Chia-Jui Weng Gow-Chin Yen | 2011 | Cancer Treatment Reviews2011,,1: | 2 |
| 11 | Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy显示文摘 | Hiroto Izumi Takayuki Torigoe Hiroshi Ishiguchi Hidetaka Uramoto Yoichiro Yoshida Mizuho Tanabe Tomoko Ise Tadashi Murakami Takeshi Yoshida Minoru Nomoto Kimitoshi Kohno | 2003 | Cancer Treatment Reviews2003,,6: | 2 |
| 12 | Interleukin-6 signaling pathway in targeted therapy for cancer显示文摘 | Yuqi Guo Feng Xu TianJian Lu Zhenfeng Duan Zhan Zhang | 2012 | Cancer Treatment Reviews2012,,7: | 2 |
| 13 | The role of the PI3K/AKT/mTOR pathway in brain tumor metastasis显示文摘The PI3K/AKT/mTOR(PAM)pathway is involved in a variety of cellular functions and often contributes to oncogenesis and cancer progression.It has been recognized that this pathway is frequently activated in the most common central nervous system cancers of adults and children,malignant gliomas and medulloblastomas(MB).In these tumors,the PAM network controls key functions necessary for cell invasion and metastasis,such as cell motility.This review summarizes the current knowledge about the role of PAM signaling in cell invasion and metastasis in gliomas and MB.Current approaches to inhibit cell invasion and metastasis by targeting the PAM pathway will also be discussed. | Silvia Crespo Marcus Kind Alexandre Arcaro | 2016 | Journal of Cancer Metastasis and Treatment2016,2,1: | 2 |
| 14 | A signature of immune function genes associated with recurrence-free survival in breast cancer patients显示文摘 | Maria Libera Ascierto Maciej Kmieciak Michael O. Idowu Rose Manjili Yingdong Zhao Margaret Grimes Catherine Dumur Ena Wang Viswanathan Ramakrishnan Xiang-Yang Wang Harry D. Bear Francesco M. Marincola Masoud H. Manjili | 2012 | Breast Cancer Research and Treatment2012,,3: | 2 |
| 15 | Targeting the Immune System in the Treatment of Non-Small-Cell Lung Cancer显示文摘 | Deepa Rangachari Julie R. Brahmer | 2013 | Current Treatment Options in Oncology2013,,4: | 2 |
| 16 | Current status and future perspectives in gastric cancer management显示文摘 | D.H. Roukos | 2000 | Cancer Treatment Reviews2000,,4: | 2 |
| 17 | Elevated Serum Periostin Levels in Patients with Bone Metastases from Breast but not Lung Cancer显示文摘 | Hidefumi Sasaki Chih-Yi Yu Meiru Dai Carmen Tam Massimo Loda Daniel Auclair Lan Bo Chen Anthony Elias | 2003 | Breast Cancer Research and Treatment2003,,3: | 2 |
| 18 | Gastric cancer: Advances in adjuvant and adjunct therapy显示文摘 | Katsuhiko Higuchi MD Alexandria Phan MD Jaffer A. Ajani MD | 2003 | Current Treatment Options in Oncology2003,,5: | 2 |
| 19 | Current Paradigm and Future Directions for Treatment of Helicobacter pylori Infection显示文摘 | Jason Ferreira Steven F. Moss | 2014 | Current Treatment Options in Gastroenterology2014,,: | 2 |
| 20 | Predictive and prognostic significance of cytoplasmic expression of ELAV-like protein HuR in invasive breast cancer treated with neoadjuvant chemotherapy显示文摘 | Jun Wang Dali Li Baocheng Wang Yun Wu | 2013 | Breast Cancer Research and Treatment2013,,2: | 2 |