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| 1 | Human mesenchymal stem cells overexpressing pigment epitheliumderived factor inhibit hepatocellular carcinoma in nude mice(摘要)显示文摘 | Gao, Y Yao, A Zhang, W Lu, S Yu, Y Deng, L Yin, A Xia, Y Sun, B Wang, X | 2010 | 南京医科大学学报(自然科学版)2010，30，8： | 25 |
| 2 | Clinical application of concentrated bone marrow aspirate in orthopaedics:A systematic review显示文摘AIM To examine the evidence behind the use of concentrated bone marrow aspirate(c BMA) in cartilage, bone, and tendon repair; establish proof of concept for the use of cB MA in these biologic environments; and provide the level and quality of evidence substantiating the use of cB MA in the clinical setting.METHODS We conducted a systematic review according to PRISMA guidelines. EMBASE, MEDLINE, and Web of Knowledge databases were screened for the use of cB MA in the repair of cartilage, bone, and tendon repair. We extracted data on tissue type, cB MA preparation, cB MA concentration, study methods, outcomes, and level of evidence and reported the results in tables and text.RESULTS A total of 36 studies met inclusion/exclusion criteria and were included in this review. Thirty-one of 36(86%) studies reported the method of centrifugation and preparation of cB MA with 15(42%) studies reporting either a cell concentration or an increase from baseline. Variation of c BMA application was seen amongst the studies evaluated. Twenty-one of 36(58%) were level of evidence Ⅳ, 12/36(33%) were level of evidence Ⅲ, and 3/36(8%) were level of evidence Ⅱ. Studies evaluated full thickness chondral lesions(7 studies), osteochondral lesions(10 studies), osteoarthritis(5 studies), nonunion or fracture(9 studies), or tendon injuries(5 studies). Significant clinical improvement with the presence of hyaline-like values and lower incidence of fibrocartilage on T2 mapping was found in patients receiving cB MA in the treatment of cartilaginous lesions. Bone consolidation and time to bone union was improved in patients receiving cB MA. Enhanced healingrates, improved quality of the repair surface on ultrasound and magnetic resonance imaging, and a decreased risk of re-rupture was demonstrated in patients receiving cB MA as an adjunctive treatment in tendon repair. CONCLUSION The current literature demonstrates the potential benefits of utilizing c BMA for the repair of cartilaginous lesions, bony defects, and tendon injuries in the clinical setting. This study also demonstrates discrepancies between the literature with regards to various methods of centrifugation, variable cell count concentrations, and lack of standardized outcome measures. Future studies should attempt to examine the integral factors necessary for tissue regeneration and renewal including stem cells, growth factors and a biologic scaffold. | Arianna L Gianakos Li Sun Jay N Patel Donald M Adams Frank A Liporace | 2017 | World Journal of Orthopedics2017，8，6： | 5 |
| 3 | SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer显示文摘 | Andreas I Papadakis Chong Sun Theo A Knijnenburg Yibo Xue Wipawadee Gremrum Michael Holzel Wouter Nijkamp Lodewyk FA Wessels Roderick L Beijersbergen Rene Bernards Sidong Huang | 2015 | Cell Research2015，25，4： | 4 |
| 4 | Standardizing catch and effort data of the Taiwanese distant-water longline fishery in the western and central Pacific Ocean for bigeye tuna, Thunnus obesus显示文摘 | Su N J Yeh S Z Sun C L Punt A E Chen Y Wang S P | | Fisheries Research0，90，13： | 1 |
| 5 | Isolation and purification of coumarin compounds from Cortex fraxinus by high - speed counter - current chromatography 显示文摘 | R M Liu Q H Sun A L Sun | 2005 | J Chromatogr A2005，1072，： | 1 |
| 6 | Markers of inflammation predict the long-term risk of developing chronic kidney disease:a population-based cohort study 显示文摘 | Shankar A Sun L Klein EB | 2011 | Kidney Int2011，80，： | 1 |
| 7 | In vitro activities of retigeric acid B alone and in combination with azole antifungal agents against Can- dida albicans显示文摘 | Sun L Sun S Cheng A | 2009 | Antimicrob Agents Chemother2009，53，4： | 1 |
| 8 | Protective effect of N-acetyl-L-cysteine on amyloid beta-peptide-induced learning and memory deficits in mice显示文摘 | Fu A L Dong Z H Sun M J | 2006 | Brain Res2006，1109，1： | 1 |
| 9 | Preparation, characterization, and application of modified chitosan sorbents for elemental mercury removal显示文摘 | ZHANG A XIANG J SUN L HU S LI P SHI J FU P SU S | 2009 | Ind Eng Chem Res2009，48，10： | 1 |
| 10 | From GO to S phase:a view of the roles played by the retinoblastoma(Rb)family members in the Rb-E2F pathway显示文摘 | Sun A Bagella L Tutton S | 2007 | J Cell Biochem2007，102，6： | 1 |
| 11 | Preparative isolation and purification of costunolide and dehydrocostuslactone from Aucklandia lappa Decne by high-speed counter-current chromatography 显示文摘 | Li A F Sun A L Liu R M | 2005 | J Chromatogr A2005，1076，12： | 1 |
| 12 | Adsorption properties of N-succinylchitosan and cross linked N-succinyl-chitosan resin with Pb(Ⅱ) as template ions显示文摘 | Sun S L Wang A Q | 2006 | Sep Purif Technol2006，51，3： | 1 |
| 13 | An RNA recog-nition motif-containing protein is required for plastid RNA edi-ting in Arabidopsis and maize显示文摘 | SUN T GERMAIN A GILOTEAUX L | 2013 | Proc Natl Acad Sci USA2013，110，12： | 1 |
| 14 | Desert heat island study in winter by mobile transect and remote sensing techniques 显示文摘 | Sun C Y Brazel A Chow W T L | 2009 | Theoretical & Applied Climatology2009，98，： | 1 |
| 15 | Validation of real-time three-dimensional echocardiography for quantifying left ventricular volumes in the presence of a left ventricular aneurysm: in vitro and in vivo studies显示文摘 | Jian Xin Qin Michael Jones Takahiro Shiota Neil L Greenberg Hiroyuki Tsujino Michael S Firstenberg Pankaj C Gupta Arthur D Zetts Yong Xu Jing Ping Sun Lisa A Cardon Jill A Odabashian Scott D Flamm Richard D White Julio A Panza James D Thomas | 2000 | Journal of the American College of Cardiology2000，，3： | 1 |
| 16 | The preparation of nano-sized H ZSM-5 zeolite and its application in the aromatization of methanol 显示文摘 | NI Y M SUN A M WU X L HAl G L HU J L LI T LI G X | 2011 | Microporous and Mesoporous Materials2011，143，2： | 1 |
| 17 | Mini-flank supra-12 th rib incision for open partial nephrectomy for renal tumor with RENAL nephrometry score>/=10:an innovation of traditional open surgery显示文摘 | Wang H Sun L A Wang Y | 2015 | Medicine(Baltimore)2015，94，13： | 1 |
| 18 | Prevalence of metabolically healthy obesity and its impacts on incidences of hypertension, dia- betes and the metabolic syndrome in Taiwan 显示文摘 | Hwang L C Bai C H Sun C A | 2012 | Asia Pac J Clin Nutr2012，21，2： | 1 |
| 19 | Performance assessment of active frequency drifting islanding detection methods显示文摘 | Lopes L A C Sun H | 2006 | IEEE Transactions on Energy Conversion2006，21，1： | 1 |
| 20 | CARD15 genotype and phenotype analysis in 55 pediatric patients with Crohn disease from Saxony, Germany显示文摘 | Sun L Roesler J Rosen- Wolff A | 2003 | J Pediatr Gastroenterol Nutr2003，37，： | 1 |
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