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| 1 | Ribavirin:Past,present and future显示文摘Before the advent of direct acting antiviral agents(DAAs) ribavirin, associated to pegylated-interferon played a crucial role in the treatment of chronic hepatitis C, preventing relapses and breakthroughs. In the present era of new potent DAAs, a place is still devoted to the drug. Ribavirin associated with sofosbuvir alone is efficient in the treatment of most cases of G2 infected patients. All options currently available for the last difficult-to-treat cirrhotic G3 patients contain ribavirin. Reducing treatment duration to 12 wk in G1 or G4 cirrhotic compensated patients is feasible thanks to ribavirin. Retreating patients with acquired anti NS5 A resistance-associated variants using ribavirin-based strategies could be useful. The addition of ribavirin with DAAs combinations however, leads to more frequent but mild adverse events especially in cirrhotic patients. Preliminary data with interferon-free second generation DAAs combinations without ribavirin suggest that future of the drug is jeopardized even in difficult-totreat patients: The optimization of ribavirin dosage according to an early monitoring of blood levels has been suggested to be relevant in double therapy with peginterferon or sofosbuvir but not with very potent combinations of more than two DAAs. | Véronique Loustaud-Ratti Marilyne Debette-Gratien Jérémie Jacques Sophie Alain Pierre Marquet DenisSautereau Annick Rousseau Paul Carrier | 2016 | World Journal of Hepatology2016，8，2： | 3 |
| 2 | HCV ‐associated B ‐cell non‐ H odgkin lymphomas and new direct antiviral agents显示文摘 | Paul Carrier Arnaud Jaccard Jérémie Jacques Tessa Tabouret Marilyne Debette‐Gratien Julie Abraham Laura Mesturoux Pierre Marquet Sophie Alain Denis Sautereau Marie Essig Véronique Loustaud‐Ratti | 2015 | Liver Int2015，，10： | 2 |
| 3 | Choice under uncertainty with the best and worst in mind: Neo-additive capacities显示文摘 | Alain Chateauneuf Jürgen Eichberger Simon Grant | 2007 | Journal of Economic Theory2007，，1： | 2 |
| 4 | Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial显示文摘 | Robert J Motzer Bernard Escudier Stéphane Oudard Thomas E Hutson Camillo Porta Sergio Bracarda Viktor Grünwald John A Thompson Robert A Figlin Norbert Hollaender Gladys Urbanowitz William J Berg Andrea Kay David Lebwohl Alain Ravaud | 2008 | The Lancet2008，，9637： | 2 |
| 5 | Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage IB–IIIA non-small-cell lung cancer (Adjuvant Navelbine International Trialist Association [ANITA]): a randomised controlled trial显示文摘 | Jean-Yves Douillard Rafael Rosell Mario De Lena Francesco Carpagnano Rodryg Ramlau Jose Luis Gonzáles-Larriba Tomasz Grodzki Jose Rodrigues Pereira Alain Le Groumellec Vito Lorusso Claude Clary Antonio J Torres Jabrail Dahabreh Pierre-Jean Souquet Julio A | 2006 | Lancet Oncology2006，，9： | 2 |
| 6 | The effect of monetary policy on real house price growth in South Africa: a factor-augmented vector autoregression (FAVAR) approach 显示文摘 | GUPTA R MARIUS J ALAIN K | 2010 | Econ Modelling2010，27，1： | 1 |
| 7 | Assessment of diabetes screening by general practitioners in France: the EPIDIA Study 显示文摘 | Cogneau J Beverley B Alain W | 2006 | DiabeticMed2006，23，7： | 1 |
| 8 | mTORCl-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs 显示文摘 | Dowling R J Topisirovic I Alain T | 2010 | Science2010，328，5982： | 1 |
| 9 | Evolution of nanoporosity in dealloying显示文摘 | Jonah E Michael J A Alain K | 2001 | Nature2001，410，： | 1 |
| 10 | On the nonlinear deformations of thin unsymmetric 0/90 composite plates under hygrothermal loads 显示文摘 | Marco G Jerome M Frederic J Alain V | 2006 | Composites Part A2006，37，4： | 1 |
| 11 | Cultivating the uncultured:limits,advances and future challenges显示文摘 | Alain K Querellon J | | 0，，： | 1 |
| 12 | An analytical approach to the performance evaluation of master-slave computational model显示文摘 | Alain J M Sophie L B Zhen L | 1998 | Parallel Computing1998，24，56： | 1 |
| 13 | Three generations of asynchronous microprocessors 显示文摘 | Alain J M Mika N Wong G G | 2003 | Design & Test of Computers2003，20，： | 1 |
| 14 | On the nonlineardeformations of thin unsymmetric 0/90composite plates underhygrothermal loads显示文摘 | Marco G Jerome M Frédéric J Alain V | 2006 | Composites Part A2006，37，4： | 1 |
| 15 | Quercetiin 3- and chromones from Callrna vulgaris显示文摘 | ALAIN S ALBERT J C MOUAD K | 1994 | Photochemistry1994，36，4： | 1 |
| 16 | Genetic algorithms using multi -objectives in a multi-agent system 显示文摘 | Alain C Galinho T Vaeher J | 2000 | Robotics and Autonomous Systems2000，33，： | 1 |
| 17 | Evolution of Nanoporosity in Dealloying 显示文摘 | Erlebacher Jonah Aziz Michael J Karma Alain | 2001 | Nature2001，410，： | 1 |
| 18 | A genetic explanation of Slaughter's concept of field cancerization:evidence and clinical implications显示文摘 | Boudewijn J M Braakhuis Maarten P Tabor J Alain Kummer | 2003 | Cancer Research2003，63，8： | 1 |
| 19 | Effects of FeCl3 on the pyrolysis of coal or coal tar pitch 显示文摘 | Boudou J P Begin D Alain E | 1998 | Fuel1998，77，6： | 1 |
| 20 | Incomplete Resolution of ST-Segment Elevation is a marker of Transient Mierocieulatory Dsfunction After Stenting for Acute Myocardial Infarction 显示文摘 | Laurent J Pierre C Alain F | 2003 | Cireulation2003，107，： | 1 |
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