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| 1 | Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents显示文摘AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary obstruction.METHODS:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French PS.Palliative patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university centers.Primary endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 years.Survival analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive characteristics.RESULTS:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for analyses.Time to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=0.006.Time to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of life.From an initially planned 120 patients,only 85 patients were recruited.CONCLUSION:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life. | Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E Kowalski Myriam Martel Viviane Adam | 2013 | World Journal of Gastroenterology2013，19，46： | 6 |
| 2 | Competing models of entrepreneurial intentions显示文摘 | Krueger J R Norris F Reilly Michael D and Carsrud Alan L | 2000 | Journal of Business Venturing2000，15，56： | 1 |
| 3 | A test method for wash-off pressure sensitive adhesives显示文摘 | BRYAN D L ALAN D R P | 1996 | International Journal of Adhesion and Adhesives1996，16，1： | 1 |
| 4 | Early microbial translocation blockade reduces SIV-mediated inflammation and viral replication显示文摘 | Kristoff Jan Haret-Richter George Ma Dongzhu Ribeiro Ruy M Xu Cuiling Cornell Elaine Stock Jennifer L He Tianyu Mobley Adam D Ross Samantha Trichel Anita Wilson Cara Tracy Russell Landay Alan Apetrei Cristian Pandrea Ivona | 2014 | Journal of Clinical Investigation2014，，： | 1 |
| 5 | Effect of granulocyte-monocyte colony-stimulating factor therapy on leukocyte function and clearance of serious infection in nonneutropenic patients显示文摘 | Alan J R Peter K L Adrienne D | 2005 | Chest2005，127，： | 1 |
| 6 | Baloon dilatation of the aortic valve in the fetus:a report of two cases显示文摘 | Maxwell D Alan L Tynan | | 0，，05： | 1 |
| 7 | Microwave pyrolysis,a novel process for recycling waste automotive engine oil显示文摘 | SU S L ALAN D R HOWARD A C | | 0，，35： | 1 |
| 8 | A QTL affecting daily feed intake maps to Chromosome2in pigs显示文摘 | Ross D H Chris S H Alan L A | 2005 | Mammalian Genome2005，16，6： | 1 |
| 9 | Electrical stimulation of repair of bone显示文摘 | Lavine L S Alan J Grodzinsky D | 1987 | J Bone Joint Surg1987，69，4： | 1 |
| 10 | Micropower impulse radar:a Novel technology for rapid,real-time detection of pneumothorax显示文摘 | Phillip D L Tracey W Alan G | 2011 | Emergency Medicine International2011，，3： | 1 |
| 11 | Phylogeny, mor- phology and pathogenicity of diaporthe and phomopsis spe- cies on almond in Portugal 显示文摘 | Eugenio L F D Jorge M S Alan J L P | 2010 | Fungal Diversity2010，44，： | 1 |
| 12 | Evaluation of an alternative IMS dissociation procedure for use with method 1623:detection of Cryptosporidium in water显示文摘 | Ware M W Wymer L Alan Lindquist H D | 2003 | Journal of Microbiological Methods2003，55，： | 1 |
| 13 | American Academy of Pediatrics ad hoe task force on definition of the medical home: the medical home 显示文摘 | Michael D John L Alan E | 1992 | Pediatrics1992，90，5： | 1 |
| 14 | Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for obsessive compulsive disorder显示文摘 | Scott L Rauch Darin D Dougherty G.Rees Cosgrove Edwin H Cassem Nathaniel M Alpert Bruce H Price Andrew A Nierenberg Helen S Mayberg Lee Baer Michael A Jenike Alan J Fischman | 2001 | Biological Psychiatry2001，，9： | 1 |
| 15 | Polymorphic forms of expressed bovine interferon-τ genes: relative transcript abundance during early placental development, promoter sequences of genes and biological activites of protein products显示文摘 | Alan D E Sandra F L Limin L | 2001 | Endocrinology2001，142，： | 1 |
| 16 | Global and regional burden of disease and risk factors,2001:systematic analysis of population health data显示文摘 | ALAN D L COLIIN D M MAJID E | 2006 | Lancet2006，367，： | 1 |
| 17 | Manipulation and mobilization the cervical spine显示文摘 | ERIC L H PETER D A ALAN H A | 1996 | Spine1996，21，： | 1 |
| 18 | 显示文摘 | Kimberly Y Donaldson Alan L Giger | 1992 | J Am Ceramic1992，75，11： | 1 |
| 19 | Electrical stimulation of repa1r of bone显示文摘 | Lavine L S Alan J Grodzinsky D | 1987 | J Bone Joint Surg1987，69，4： | 1 |
| 20 | Micropower impulse radar: a novel technology for rapid,real-time detection of pneumothorax显示文摘 | Phillip D L Traeey W Alan G | 2011 | Eme- rgency Medicine International2011，3，： | 1 |
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