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14篇 您的检索式：作者名="ALUN G"

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		题名	作者	年代	出处	被引量
	1	Calcium signaling and T-type calcium channels in cancer cell cycling显示文摘Regulation of intracellular calcium is an important signaling mechanism for cell proliferation in both normal and cancerous cells. In normal epithelial cells, free calcium concentration is essential for cells to enter and accomplish the S phase and the M phase of the cell cycle. In contrast, cancerous cells can pass these phases of the cell cycle with much lower cytoplasmic free calcium concentrations, indicating an alternative mechanism has developed for fulfilling the intracellular calcium requirement for an increased rate of DNA synthesis and mitosis of fast replicating cancerous cells. The detailed mechanism underlying the altered calcium loading pathway remains unclear; however, there is a growing body of evidence that suggests the T-type Ca2+ channel is abnormally expressed in cancerous cells and that blockade of these channels may reduce cell proliferation in addition to inducing apoptosis. Recent studies also show that the expression of T-type Ca2+ channels in breast cancer cells is proliferation state dependent, i.e. the channels are expressed at higher levels during the fast-replication period, and once the cells are in a non-proliferation state, expression of this channel isminimal. Therefore, selectively blocking calcium entry into cancerous cells may be a valuable approach for preventing tumor growth. Since T-type Ca2+ channels are not expressed in epithelial cells, selective T-type Ca2+ channel blockers may be useful in the treatment of certain types of cancers.	James T Taylor Xiang-Bin Zeng Jonathan E Pottle Kevin Lee Alun R Wang Stephenie G Yi lennifer A S Scruggs Suresh S Sikka Ming Li	2008	World Journal of Gastroenterology2008，14，32：	12
	2	The relationship between apolipoprotein AI-containing lipoprotein fractions and environmental factors: the prospective epidemiological study of myocardial infarction (PRIME study)显示文摘	Gérald Luc Jean-Marie Bard Alun Evans Dominique Arveiler Jean-Bernard Ruidavets Philippe Amouyel Pierre Ducimetiere	2000	Atherosclerosis2000，，2：	1
	3	Interleukin-18 and the Risk of Coronary Heart Disease in European Men: The Prospective Epidemiological Study of Myocardial Infarction (PRIME)显示文摘	Stefan Blankenberg Gérald Luc Pierre Ducimetière Dominique Arveiler Jean Ferrières Philippe Amouyel Alun Evans Fran?ois Cambien Laurence Tiret	2003	Circulation: Journal of the American Heart Association2003，，20：	1
	4	Agricultural land protection in China: a case study of local governance in Zhejiang Province显示文摘	SKINNER MARK W KUHN RICHARD G JOSEPH ALUN E	2001	Land Use Policy2001，6，18：	1
	5	Agricultural land protection in China: a case study of local governance in Zhejiang province显示文摘	Mark W S Richard G K Alun E J	2001	Land Use Policy2001，18，2：	1
	6	Interleukin-18 and the Risk of Coronary Heart Disease in European Men: The Prospective Epidemiological Study of Myocardial Infarction (PRIME)显示文摘	Stefan Blankenberg Gérald Luc Pierre Ducimetière Dominique Arveiler Jean Ferrières Philippe Amouyel Alun Evans Fran?ois Cambien Laurence Tiret	2003	Circulation: Journal of the American Heart Association2003，，20：	1
	7	Lipoprotein (a) as a predictor of coronary heart disease: the PRIME Study显示文摘	Gérald Luc Jean-Marie Bard Dominique Arveiler Jean Ferrieres Alun Evans Philippe Amouyel Jean-Charles Fruchart Pierre Ducimetiere	2002	Atherosclerosis2002，，2：	1
	8	Lack of association between complement factor H polymorphisms and coronary artery disease or myocardial infarction显示文摘	Viviane Nicaud Carole Francomme Jean-Bernard Ruidavets Gérald Luc Dominique Arveiler Frank Kee Alun Evans Caroline Morrison Stefan Blankenberg Fran?ois Cambien Laurence Tiret	2007	Journal of Molecular Medicine2007，，7：	1
	9	Hydroxyproline Quantification for the Estimation of Collagen in Tissue Using Multiple Reaction Monitoring Mass Spectrometry 显示文摘	MICHELLE L C PETER G A ALUN J	2008	Journal of Chromatography A2008，1212，：	1
	10	Agricultural land protection in China:a case study of local governance in Zhejiang province显示文摘	Mark W S Richard G K Alun E J		0，，02：	1
	11	Jones Effects of Resistance Exercise Volume and Nutritional Supplementation on Anabolic and Catabolic Hormones 显示文摘	ALUN G WILLIAMS A Naim Ismail Anita Sharma David A	2002	Eur J Appl Physiol2002，，86：	1
	12	The symptomatic ca- rotid plaque显示文摘	Jonathan G Roger M Greenhalgh - Alun H	2000	Stroke2000，31，2：	1
	13	Similarity of polygenic profiles limits the potential for elite human physical performance显示文摘	ALUN G WILLIAMS JONATHAN P FOLLAND	2008	J Physiol2008，586，1：	1
	14	Plasma cystatin-C and development of coronary heart disease: The PRIME Study显示文摘	Gérald Luc Jean-Marie Bard Céline Lesueur Dominique Arveiler Alun Evans Philippe Amouyel Jean Ferrieres Irène Juhan-Vague Jean-Charles Fruchart Pierre Ducimetiere	2005	Atherosclerosis2005，，2：	1

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