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| 1 | Tomato lycopene attenuates myocardial infarction induced by isoproterenol:Electrocardiographic,biochemical and anti-apoptotic study显示文摘Objective:To assess the protective effects of lycopene on electrocardiographic,hemodynamic, biochemical and apoptotic changes in isoproterenol induced myocardial infarction.Methods: Myocardial infarction was induced in rats by subcutaneous injection of isoproterenol(200 mg/kg) for two consecutive days at an interval of 24 h.Rats were treated with lycopene(10 mg/kg/day, p.o.) for a period of 30 days and isoproterenol(ISO) was injected on the 29th and 30th day.At the end of experiment i.e.on the 31st day electrocardiographic,hemodynamic,biochemical and apoptotic changes were monitored from control and experimental groups.Results:ISO injected ruts showed a significant alteration in electrocardiograph pattern and hemodynamic changes(i.e. systolic,diastolic and mean arterial pressure).It also showed significant increase in C-reactive protein,myeloperoxidase,nitrite levels and Caspase-3 protease activity.In addition,it also exhibited alteration in the levels of electrolytes(Na^+,K^+ and Ca^(2+),vitamin E,uric acid and serum protein.Cel electrophoresis of ISO injected rats showed increase in DNA fragmentation.Triphenyl tetrazolium chloride staining of the heart section shows increase area of infarction in ISO injected rats.Pre-co-treatment with lycopene significantly prevented the ISO induced ullerution in ECC, haemodynamic,biochemical and apoptotic changes.Conclusions:The present result shows that treatment of lycopene in ISO injected rats significantly attenuates induced myocardial infarction. | Aman Upaganlawar Vaibhav Patel Balaraman R | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，5： | 6 |
| 2 | Natural variations in the contents of structural elements of water-extractable non-starch polysaccharides in white flour 显示文摘 | Anderson R Westerlund E Aman P | 1994 | Journal of Cereal Science1994，19，： | 1 |
| 3 | Application of HPLC coupled with DAD, APcI-MS and NMR to the analysis of lutein and zeaxanthin stereoisomers in thermally processed vegetables显示文摘 | AMAN R BIEHL J CARLE R | 2005 | Food Chemistry2005，92，： | 1 |
| 4 | Application of HPLC coupled with DAD, APCI-MS and NMR to the analysis of lutein and zeaxanthin stereoisomers in thermally processed vegetables显示文摘 | Aman R Biehl J Carle R | 2005 | Food Chem2005，92，： | 1 |
| 5 | Discovery of a new class of immunoglobulin heavy chain from fugu 显示文摘 | Savan R Aman A Saot K | 2005 | Eur J Im- munol2005，35，11： | 1 |
| 6 | The immunoregulatory mediator maerophage migration inhibitory factor catalyzes a tautomerization reaction显示文摘 | Rosengren E Bueala R Aman P | 1996 | Mol Med1996，2，1： | 1 |
| 7 | The species concept for prokaryotes 显示文摘 | Rosello M R Aman R | 2001 | FEMS Microbe Review2001，25，： | 1 |
| 8 | The species concept for prokaryotes 显示文摘 | Rosello M R Aman R | 2001 | FEMS Microbiology Reviews2001，25，1： | 1 |
| 9 | Selection for haploidy inducing protential in maize显示文摘 | Aman M A Sarkar K R | 1978 | Indian Journal of Genet and Plant Breeding1978，38，3： | 1 |
| 10 | Multiplex PCR for rapid diagnosis of tuberculous meningitis显示文摘 | Kusum S Aman S Pallab R | 2011 | J Neurol2011，258，： | 1 |
| 11 | The value of synovial fluid analysis in the assessment of knee joint destruction in arthritis in a three-year follow up study显示文摘 | Aman S Risteli J Luukkainen R | | 0，，9： | 1 |
| 12 | Preparation of (2R,3R)-Ethyl 1-1-Benzhydryl-3-(4-bromophenyl)aziridine 2-Carboxylate显示文摘 | AMAN A D ROBERTO M R WILLIAM D W | 2011 | Org Synth2011，88，： | 1 |
| 13 | Application of HPLC coupled with DAD,APcI-MS and NMR to the analysis of lutein and zeaxanthin stereoisomers in thermally processed vegetables显示文摘 | Aman R Beihl J Carle R | 2005 | Food Chemistry2005，92，44： | 1 |
| 14 | Enhanced pro- duction of cellulose degrading CMCase by newly isolated strain of Aspergillus versicolor 显示文摘 | QAISAR S ZOHRA R AMAN A | 2014 | Carbohydrate Polymers2014，104，15： | 1 |
| 15 | Isolation of carotenoids from plant materials and dietary supplements by high-speed counter-current chromatography显示文摘 | AMAN R CARLE R CONRAD J | 2005 | J Chromatogra A2005，1074，： | 1 |
| 16 | Multiplex PCR for rapid diagnosis of tuberculous meningitis显示文摘 | Kusum S Aman S Pallab R | 2011 | J Neurol2011，258，10： | 1 |
| 17 | Multiplex PCR for rapid diagnosis of tuberculous meningitis显示文摘 | Kusum S Aman S Pallab R | | 0，，10： | 1 |
| 18 | Selection for haploidy inducing potential in maize显示文摘 | AMAN M A SARKAR K R | | 0，，03： | 1 |
| 19 | Characterisation of dietary fibre components in rye products 显示文摘 | Rakha A Aman P Andersson R | 2010 | Food Chemistry2010，119，3： | 1 |
| 20 | Grandual enzymatic modification of barley and potato amylopectin显示文摘 | Frigard T Andersson R Aman P | 2001 | Carbohydrate Polymers2001，47，： | 1 |
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