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| 1 | Current concepts on osteonecrosis of the femoral head显示文摘It is estimated that 20000 to 30000 new patients are diagnosed with osteonecrosis annually accounting for approximately 10% of the 250000 total hip arthroplasties done annually in the United States. Thelack of level 1 evidence in the literature makes it difficult to identify optimal treatment protocols to manage patients with pre-collapse avascular necrosis of the femoral head, and early intervention prior to collapse is critical to successful outcomes in joint preserving procedures. There have been a variety of traumatic and atraumatic factors that have been identified as risk factors for osteonecrosis, but the etiology and pathogenesis still remains unclear. Current osteonecrosis diagnosis is dependent upon plain anteroposterior and frog-leg lateral radiographs of the hip, followed by magnetic resonance imaging(MRI). Generally, the first radiographic changes seen by radiograph will be cystic and sclerotic changes in the femoral head. Although the diagnosis may be made by radiograph, plain radiographs are generally insufficient for early diagnosis, therefore MRI is considered the most accurate benchmark. Treatment options include pharmacologic agents such as bisphosphonates and statins, biophysical treatments, as well as joint-preserving and joint-replacing surgeries. the surgical treatment of osteonecrosis of the femoral head can be divided into two major branches: femoral head sparing procedures(FHSP) and femoral head replacement procedures(FHRP). In general, FHSP are indicated at pre-collapse stages with minimal symptoms whereas FHRP are preferred at post-collapse symptomatic stages. It is difficult to know whether any treatment modality changes the natural history of core decompression since the true natural history of core decompression has not been delineated. | Joaquin Moya-Angeler Arianna L Gianakos Jordan C Villa Amelia Ni Joseph M Lane | 2015 | World Journal of Orthopedics2015，6，8： | 94 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Long-term Changes in Corneal Morphology Induced by Overnight Orthokeratology显示文摘 | Amelia Nieto-Bona Ana Gonzá lez-Mesa Ma Paz Nieto-Bona Cé sar Villa-Collar Amalia Lorente-Velá zquez | 2011 | Current Eye Research2011，，10： | 2 |
| 4 | Croce miR-15 and miR-16 induce apoptosisby targeting BCL2显示文摘 | Amelia C Carlo M | 2005 | PNAS2005，39，13： | 1 |
| 5 | Portopulmonary hypertension- Clinical and investigative medicine显示文摘 | Eugenia H Amelia V Gregorio C | 2011 | Med Clin Exper2011，34，3： | 1 |
| 6 | Strategically managed buyer-supplier relationships and performance outcomes显示文摘 | AMELIA S C JOHN N P | 1999 | Journal of Operations Management1999，，17： | 1 |
| 7 | Trucking industry demand for urban shared use freight terminals显示文摘 | Amelia C Regan Thomas F Golob | 2005 | Transportation2005，32，： | 1 |
| 8 | Mir-15 and mir-16 induce apoptosis by targeting Bcl-2 显示文摘 | AMELIA C GEORGE A C MULLER F | 2005 | Proc Natl Acad Sci USA2005，102，13： | 1 |
| 9 | Impacts of Infor- mation Technology on Personal Travel and Commercial Vehicle Operations: Research Challenges and Opportunities显示文摘 | Thomas F G Amelia C R | 2001 | Transporta- tion Research Part C2001，9，2： | 1 |
| 10 | AmiGO:online access to ontology and annotation data显示文摘 | Seth C Amelia I Christopher J | 2009 | Bioinformatics2009，25，： | 1 |
| 11 | Relationship between slightly elevated NT-proBNP and alterations in diastolic function detected by echocardiography in patients without structural heart disease显示文摘 | Antonio Barragán Juan Lacalzada Alejandro de la Rosa Antonia María de Vera Amelia Duque César Perera Antonio Lara Ignacio Laynez | 2007 | International Journal of Cardiology2007，，3： | 1 |
| 12 | A comparison of imaging conditions for wave-equation shot-profile migration 显示文摘 | Jorg S Jesse C C Amelia N | 2008 | Geophysics2008，73，6： | 1 |
| 13 | A Unique 7p/12q Chromosomal Abnormality Associated With Recurrent Abortion and Hypofibrinogenemia显示文摘 | Kitchens Amelia C | 1987 | Blood1987，170，4： | 1 |
| 14 | miR-15 and miR-16 induce apoptosis by targeting BCL2 显示文摘 | Amelia C George AC Muller F | 2005 | Proc Natl Acad Sci2005，102，13： | 1 |
| 15 | A comparison of imaging conditions for wave-equation shot-file migration显示文摘 | Jorg Schleicher Jesse C Costa Amelia Novais | 2008 | Geophysics2008，73，6： | 1 |
| 16 | Modification of the surface properties of an activated carbon by oxygen plasma treatment显示文摘 | A B Garcla Amelia M-A C A L Leon | 1998 | Fuel1998，77，6： | 1 |
| 17 | The perceived usefulness of different sources of traffic information to trucking operations 显示文摘 | THOMAS F G AMELIA C R | 2002 | Transportation Research Part E2002，38，2： | 1 |
| 18 | Activity of cabazi- taxel in castration-resistant prostate cancer progressing after docetaxel and next-generation endocrine agents 显示文摘 | Pezaro C J Omlin A G Amelia A | 2014 | Eur Urol2014，66，3： | 1 |
| 19 | Long-term doxycyclinecontrolled expression of human tyrosine hydroxylase atter direct adenovirus-mediated gene transfer to a rat model of Parkinson's diease显示文摘 | Olga C Amelia SC Phillippe C | 1999 | PNAS1999，96，12： | 1 |
| 20 | Mathematical modeling of the heat and mass transfer in a stationary potato sphere impinged by a single round liquid jet in a hydro fluidization system显示文摘 | Juan M Peralta Amelia C Rubiolo Susana E Zorrilla | 2012 | Journal of Food Engineering2012，109，3： | 1 |
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