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| 1 | 冠状动脉内影像学临床应用专家共识(第一部分):对冠状动脉介入治疗的指导与优化显示文摘欧洲心血管介入协会(EAPCI)专家组系统总结了血管内超声(IVUS)和光学相干断层成像(OCT)这两种血管内影像学检查临床应用指征的现有证据,提供了关于IVUS和OCT指导经皮冠状动脉介入治疗(PCI)的应用价值,并明确了最可能从腔内影像学指导的介入治疗中获得临床收益的患者或病变类型,同时详细论述了PCI前如何使用IVUS或OCT优化支架尺寸(支架长度和直径)和手术策略的选择。此外,专家推荐对支架失败(支架内再狭窄或支架内血栓形成)的患者应常规进行冠状动脉内影像学检查,并首选OCT。最后,重点论述了IVUS和OCT在指导PCI和评估支架失败两个方面的优势和局限性,并对未来需要深入研究的领域进行了展望。 | Lorenz Raber Gary S Mintz Konstantinos C Koskinas Thomas W Johnson Niels R Holm Yoshinubo Onuma Maria D Radu Michael Joner Bo Yu Haibo Jia Nicolas Meneveau Jose M.de la Torre Hemandez Javier Escaned Jonathan Hill Francesco Prati Antonio Colombo Carlo di Mario Evelyn Regar Davide Capodanno William Wijns Robert A Byme Giulio Guagliumi | 2019 | 中华心血管病杂志2019，47，1： | 17 |
| 2 | Endoscopic submucosal dissection training with pig models in a Western country显示文摘AIM:To test a strategy for endoscopic submucosal dissection(ESD) training in animal models designed to overcome the initial learning curve.METHODS:ESD was attempted in ex vivo and in vivo pig models.Thirty ESD procedures were attempted in the esophagus(n=9) or the stomach(n=21).The ex vivo model was used until initial competence was achieved.In the in vivo model,several ESD procedures were performed in up to 3 sessions.The following variables were analyzed:specimen size,complete and en bloc resection rate,time for circumferential incision,time for submucosal dissection,total ESD duration,and complications.RESULTS:Complete resection was achieved in 28 cases(en bloc 27);2 could not be completed(one perforation,one technical diff iculty).The mean ± SD time for circumferential incision was 36.2±16.8 min(range:8-87 min),and the mean±SD time for submucosal dissection was 45.1±35.7 min(range:9-196 min).The mean±SD size of the resected specimens was 45.2±17.8 mm.The mean±SD total resection time was signif icantly increased for the gastric cases performed in the f irst half of the study(n=13) than in the second half(n=8)(98.9±62.4 min vs 61.7±17.6 min,P=0.04),although the specimen size did not differ.CONCLUSION:Training in animal models could help endoscopists overcome the learning curve before starting ESD in humans. | Adolfo Parra-Blanco María Rosa Arnau David Nicolás-Pérez Antonio Z Gimeno-García Nicolás González Juan A Díaz-Acosta Alejandro Jiménez Enrique Quintero | 2010 | World Journal of Gastroenterology2010，16，23： | 9 |
| 3 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 4 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet . 2013 (9867)2013，，9867： | 2 |
| 5 | Nitrate is reduced by heterotrophic bacteria but not transterred to prochlorococcus in non-axenic cultures显示文摘 | Antonio L L Jesus D Sabah E A | 2002 | FEMS Microbiology Ecology2002，1，： | 1 |
| 6 | 查看详情显示文摘 | László P Juan F G R Péter F Attila G Mihály D László A Bienvenida G Antonio M | | 0，，03： | 1 |
| 7 | Accelerated Cooling of Steel Plates: The Time Has Come显示文摘 | Antonio A G Jose Herbert D S | 2008 | Journal of ASTM International2008，5，8： | 1 |
| 8 | Some aspects of niching genetic algorithms applied to electromagnetic device optimization显示文摘 | Antonio G Lowther D A | 2000 | IEEE Transactions on Magnetics2000，36，4： | 1 |
| 9 | Mammary hamartomas: An immunohistochemical study of 41 cases 显示文摘 | Chiacchio R Panico L D'Antonio A | 1994 | Pathol Res Pract1994，190，： | 1 |
| 10 | Late Remodeling Around a Proximally HA-coated Tapered Titanium Femoral Component显示文摘 | Capello W N D'Antonio J A Geesink R G | | 0，，： | 1 |
| 11 | Oxidation of aromatic sub- strates in water/goethite slurry by means of hydrogen peroxide显示文摘 | Andreozzi R Antonio A D Marotta R | 2002 | Water Research2002，36，19： | 1 |
| 12 | Oxidation of aromatic substrates in water/goethite slurry by means of hydrogen peroxide 显示文摘 | Roberto A Antonio D Raffaele M | 2002 | Water Res2002，36，19： | 1 |
| 13 | Use of pruning waste compost as a component in soilless growing media显示文摘 | Benito M Masaguer A Antonio R D | 2005 | Bioresource Technology2005，96，： | 1 |
| 14 | 显示文摘 | Tadeu A Antonio J Mateus D | 2004 | Applied Acoustics2004，65，1： | 1 |
| 15 | Role of IL-15 in immune-mediated and infectious diseases显示文摘 | Antonio D S Sandra A C Francesea V | 2011 | Cytokine Growth Factor Rev2011，22，1： | 1 |
| 16 | Shrub expansion in montane meadows显示文摘 | Berlow E L D Antonio C M Reynolds S A | 2002 | Ecological Applications2002，12，4： | 1 |
| 17 | Biological Signatures of Asymptomatic Extra- and Intracranial Atherosclerosis: The Barcelona-AsIA (Asymptomatic Intracranial Atherosclerosis) Study显示文摘 | Elena López-Cancio Amparo Galán Laura Dorado Marta Jiménez María Hernández Mónica Millán Silvia Reverté Anna Su?ol Jaume Barallat Anna Massuet Maria Teresa Alzamora Antonio Dávalos Juan Francisco Arenillas | 2012 | Stroke2012，，10： | 1 |
| 18 | Measurement and simulation of climate inside Almeria type greenhouses using computational fluiddynamics显示文摘 | Francisco D M Diege L V Antonio J A | 2004 | Agricultural and forest Meteorology2004，，125： | 1 |
| 19 | In situ Ru K-edge X-ray absorption fine structure studies of electroprecipitated ruthenium dioxide film with relevance to supercapacitor applications显示文摘 | MO Y ANTONIO M R SCHERSON D A | 2000 | Phys Chem B2000，104，： | 1 |
| 20 | Transforming growth factor al- pha,amphiregulin and cripto-1 are frequently expressed in advanced human ovarian carcinomas显示文摘 | D'Antonio A Losito S Pignata S | 2002 | Int J Oncol2002，21，5： | 1 |
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