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| 1 | Circular noncoding RNAs as potential therapies and circulating biomarkers for cardiovascular diseases显示文摘在染色体宽的分析和定序 RNA 技术的最近的前进导致了小 noncoding RNA 的发现,例如 microRNAs (米尔) ,以及两线性长 noncoding RNA (lncRNAs ) 和圆形的长 noncoding RNA (circRNAs ) 。在心血管的疾病(CVD ) 的治疗,预后和诊断的米尔和 lncRNAs 的重要性广泛地被报导了。我们以前也为 CVD 在治疗并且作为 biomarkers 考察了他们的含意。更最近, circRNAs 也在 CVD 作为重要管理者出现了。CircRNAs 是被背送信人前 RNA (pre-mRNAs ) 的特定的区域拼接产生的圆形的染色体产品。对 circRNAs 的成长兴趣导致了他们的 pathophysiological 功能的一个宽数组的发现。CircRNAs 被显示了是象心肌的梗塞,动脉粥样硬化,心肌症和心脏的纤维变性那样的 CVD 的关键管理者。因此, circRNAs 最近为 CVD 作为潜在的治疗学的目标和 biomarkers 被建议了。在这评论,我们在 circRNAs 上总结文学的当前的状态,以他们的生物的续生说和行动的全球机制开始。我们然后在各种各样的 CVD 提供他们的参与的一个提要。最后,我们为 CVD 的早察觉作为 biomarkers 强调 circRNAs 的大潜力,并且讨论作为有希望的 biomarkers 加亮 circRNAs 的利用的几项专利和最近的报纸。 | Ahmed S BAYOUMI Tatsuya AONUMA Jian-peng TEOH Yao-liang TANG II-man KIM | 2018 | Acta Pharmacologica Sinica2018，39，7： | 16 |
| 2 | Early Repolarization Is an Independent Predictor of Occurrences of Ventricular Fibrillation in the Very Early Phase of Acute Myocardial Infarction显示文摘 | Yoshihisa Naruse Hiroshi Tada Yoshie Harimura Mayu Hayashi Yuichi Noguchi Akira Sato Kentaro Yoshida Yukio Sekiguchi Kazutaka Aonuma | 2012 | Circulation: Arrhythmia and Electrophysiology2012，，3： | 2 |
| 3 | Retinal cell death by light damage 显示文摘 | Aonuma H Yamazaki R Watanabe I | 1999 | Jpn J Ophthalmol1999，43，： | 1 |
| 4 | How to diagnose,locate,and ablate coronary cusp ventriculartachycardia显示文摘 | Aonuma K Yamauchi Y | 2002 | J Cardiovasc Electrophysiol2002，13，6： | 1 |
| 5 | Critical role of nitric oxide-cGMP cascade in the formation of cAMP- dependent long-term memory显示文摘 | MATSUMOTO Y UNOKI S AONUMA H | 2006 | Learn Mere2006，13，： | 1 |
| 6 | Chronic hemodynamic effects after radiofrequency catheter ablation of frequent monomorphic ventricular premature beats 显示文摘 | Sekiguchi Y Aonuma Y Obayashi T | 2005 | Cardiovasc Electrophysiol2005，16，10： | 1 |
| 7 | Electrocardiographic characteristics of repetitive monomorphic right ventricular tachyear- dia originating near the His-bundle显示文摘 | Yamauehi Y Aonuma K Takahashi A | 2005 | J Cardiovasc EIectrophysi- o12005，16，10： | 1 |
| 8 | Osteocyte calciumsignaling response to bone matrix deformation 显示文摘 | ADACHI T B AONUMA Y ITO S I | 2009 | J Biomech2009，42，15： | 1 |
| 9 | Rapid identification of Plasmodium-carrying mosquitoes using loop-mediated isothermal amplification 显示文摘 | Aonuma H Suzuki M Iseki H | 2008 | Biochem Biophys Res Commun2008，376，4： | 1 |
| 10 | Identification and expression analysis of the genes involved in serotonin biosynthesis and transduction in the field cricket Gryllus bimaculatus显示文摘 | WATANABE T SADAMOTO H AONUMA H | 2011 | Insect Molecular Biology2011，20，5： | 1 |
| 11 | Rapid identification of Plasmodium-carrying mosquitoes using loop-mediated isothermal amplification 显示文摘 | Aonuma H Suzuki M Iseki H | 2008 | Biochem Biophys Res Commuu2008，376，4： | 1 |
| 12 | Astrocyte differentiation of neural prcursor cells is enhanced by retinoic acid through a change in epigenetic modification显示文摘 | Asano H Aonuma M Sanosaka T | | 0，，： | 1 |
| 13 | Electrocardiographic characteristics of left ventricular outflow tract tachycardia 显示文摘 | Hachiya H Aonuma K Yamauchi Y | 2000 | PACE2000，23，12： | 1 |
| 14 | Electrocar- diographic and electrophysiologic characteristics of ventric- ular tachycardia originating within the pulmonal-y artery 显示文摘 | Sekiguchi Y Aonuma K Takahashi A | 2005 | J Am Coil Cardiol2005，45，6： | 1 |
| 15 | How to diagnose,locate, and ablate coronary cusp ventricular tachycardia 显示文摘 | Hachiya H Aonuma K Yamauchi Y | 2002 | J Cardiovasc Electrophysiol2002，13，： | 1 |
| 16 | Investigation of a novel algorithm for synchronized left-ventricular pacing and ambulatory optimization of cardiac resynchronization therapy: Results of the adaptive CRT trial显示文摘 | David O. Martin Bernd Lemke David Birnie Henry Krum Kathy Lai-Fun Lee Kazutaka Aonuma Maurizio Gasparini Randall C. Starling Goran Milasinovic Tyson Rogers Alex Sambelashvili John Gorcsan Mahmoud Houmsse | 2012 | Heart Rhythm2012，，11： | 1 |
| 17 | Dissimilar metal joining of ZK60 magnesium alloy and titanium by friction stir welding 显示文摘 | Masayuki Aonuma Kazuhiro Nakata | 2012 | Materials Science and Engineering B2012，，177： | 1 |
| 18 | Dissimilar metal joining of ZK60 magnesium alloy and titanium by friction stir welding显示文摘 | Masayuki Aonuma Kazuhiro Nakata | 2012 | Materials Science and Engineering B2012，177，： | 1 |
| 19 | Rapid identification of plasmodium-carrying mosquitoes using loop-mediated isothermal amplification显示文摘 | Aonuma H | 2008 | Biochem Biophys Res Commun2008，376，4： | 1 |
| 20 | Low serum levels of undercarboxylated osteocalcin in postmenopausal osteoporotic women receiving an inhibitor of bone resorption显示文摘 | Aonuma H Miyakoshi N Hongo M | 2009 | Tohoku J Exp Med2009，218，3： | 1 |
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